Impact of aortic valve calcification, as measured by MDCT, on survival in patients with aortic stenosis: Results of an international registry study

Journal of the American College of Cardiology

Volumn 64, Issue 12, 2014, Pages 1202-1213

  Clavel, Marie Annick ^a   Pibarot, Philippe ^b   Messika Zeitoun, David ^c,d   Capoulade, Romain ^b   Malouf, Joseph ^a   Aggarval, Shivani ^a   Araoz, Phillip A ^a   Michelena, Hector I ^a   Cueff, Caroline ^c   Larose, Eric ^b   Miller, Jordan D ^a   Vahanian, Alec ^c,d   Enriquez Sarano, Maurice ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITÉ LAVAL   (Canada)

^c BICHAT HOSPITAL   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

aortic valve calcification; aortic valve stenosis; Doppler echocardiography; multidetector computed tomography; survival

Indexed keywords

ADULT; AGE; AGED; AORTA STENOSIS; AORTA VALVE CALCIFICATION; AORTA VALVE DISEASE; ARTICLE; CLINICAL TRIAL; CONSERVATIVE TREATMENT; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE SEVERITY; DOPPLER ECHOCARDIOGRAPHY; FEMALE; FOLLOW UP; GENDER; HEART HEMODYNAMICS; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; MULTIDETECTOR COMPUTED TOMOGRAPHY; OVERALL SURVIVAL; PREDICTIVE VALUE; SURVIVAL RATE; SYMPTOM; AORTA VALVE; AORTA VALVE STENOSIS; CALCINOSIS; INTERNATIONAL COOPERATION; MIDDLE AGED; PATHOLOGY; PROCEDURES; PROSPECTIVE STUDY; RADIOGRAPHY; REGISTER; TRENDS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AORTIC VALVE; AORTIC VALVE STENOSIS; CALCINOSIS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTERNATIONALITY; MALE; MIDDLE AGED; MULTIDETECTOR COMPUTED TOMOGRAPHY; PROSPECTIVE STUDIES; REGISTRIES; SURVIVAL RATE;

EID: 84908022512     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2014.05.066     Document Type: Article

References (38)

1. R.O. Bonow, B.A. Carabello, and C. Kanu ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons J Am Coll Cardiol 48 2006 e1 e148
2. A. Vahanian, O. Alfieri, and F. Andreotti Guidelines on the management of valvular heart disease (version 2012) Eur Heart J 33 2012 2451 2496
3. J. Ross Jr., and E. Braunwald Aortic stenosis Circulation 38 1968 61 67
4. C.M. Otto Calcific aortic valve disease: outflow obstruction is the end stage of a systemic disease process Eur Heart J 30 2009 1940 1942
5. B. Iung, G. Baron, and E.G. Butchart A prospective survey of patients with valvular heart disease in Europe: the Euro Heart Survey on Valvular Heart Disease Eur Heart J 24 2003 1231 1243
6. J. Malouf, T. Le Tourneau, and P. Pellikka Aortic valve stenosis in community medical practice: determinants of outcome and implications for aortic valve replacement J Thorac Cardiovasc Surg 144 2012 1421 1427
7. D. Messika-Zeitoun, M.C. Aubry, and D. Detaint Evaluation and clinical implications of aortic valve calcification measured by electron-beam computed tomography Circulation 110 2004 356 362
8. M.J. Blaha, M.J. Budoff, and J.J. Rivera Relation of aortic valve calcium detected by cardiac computed tomography to all-cause mortality Am J Cardiol 106 2010 1787 1791
9. D. Pradelli, G. Faden, and G. Mureddu Impact of aortic or mitral valve sclerosis and calcification on cardiovascular events and mortality: a meta-analysis Int J Cardiol 170 2013 e51 e55
10. S.R. Aggarwal, M.A. Clavel, and D. Messika-Zeitoun Sex differences in aortic valve calcification measured by multidetector computed tomography in aortic stenosis Circ Cardiovasc Imaging 6 2013 40 47
11. M.A. Clavel, D. Messika-Zeitoun, and P. Pibarot The complex nature of discordant severe calcified aortic valve disease grading: new insights from combined Doppler-echocardiographic and computed tomographic study J Am Coll Cardiol 62 2013 2329 2338
12. R. Rosenhek, T. Binder, and G. Porenta Predictors of outcome in severe, asymptomatic aortic stenosis N Engl J Med 343 2000 611 617
13. R. Rosenhek, U. Klaar, and C. Scholten Risk stratification in mild and moderate aortic stenosis by assessment of aortic valve calcification (abstr) J Am Coll Cardiol 41 Suppl A 2003 506A
14. H. Utsunomiya, H. Yamamoto, and T. Kitagawa Incremental prognostic value of cardiac computed tomography angiography in asymptomatic aortic stenosis: significance of aortic valve calcium score Int J Cardiol 168 2013 5205 5211
15. H. Baumgartner, J. Hung, and J. Bermejo Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice J Am Soc Echocardiogr 22 2009 1 23 quiz 101-2
16. C. Cueff, J.M. Serfaty, and C. Cimadevilla Measurement of aortic valve calcification using multislice computed tomography: correlation with haemodynamic severity of aortic stenosis and clinical implication for patients with low ejection fraction Heart 97 2010 721 726
17. A.S. Agatston, W.R. Janowitz, F.J. Hildner, N.R. Zusmer, M. Viamonte Jr., and R. Detrano Quantification of coronary artery calcium using ultrafast computed tomography J Am Coll Cardiol 15 1990 827 832
18. S. Palta, A.M. Pai, K.S. Gill, and R.G. Pai New insights into the progression of aortic stenosis: implications for secondary prevention Circulation 101 2000 2497 2502
19. S. Achenbach, V. Delgado, J. Hausleiter, P. Schoenhagen, J.K. Min, and J.A. Leipsic SCCT expert consensus document on computed tomography imaging before transcatheter aortic valve implantation (TAVI)/transcatheter aortic valve replacement (TAVR) J Cardiovasc Comput Tomogr 6 2012 366 380
20. B.A. Carabello Introduction to aortic stenosis Circ Res 113 2013 179 185
21. J. Monckeberg [Normal histological construction and sclerosis of the aortic valves.] Virchows Arch Pathol Anat 176 1904 472 514
22. C.M. Otto, J. Kuusisto, D.D. Reichenbach, A.M. Gown, and K.D. O'Brien Characterization of the early lesion of 'degenerative' valvular aortic stenosis. Histological and immunohistochemical studies Circulation 90 1994 844 853
23. D. Messika-Zeitoun, L.F. Bielak, and P.A. Peyser Aortic valve calcification: determinants and progression in the population Arterioscler Thromb Vasc Biol 27 2007 642 648
24. D.S. Owens, R. Katz, J. Takasu, R. Kronmal, M.J. Budoff, and K.D. O'Brien Incidence and progression of aortic valve calcium in the Multi-ethnic Study of Atherosclerosis (MESA) Am J Cardiol 105 2010 701 708
25. J.D. Miller, R.M. Weiss, and D.D. Heistad Calcific aortic valve stenosis: methods, models, and mechanisms Circ Res 108 2011 1392 1412
26. M.A. Clavel, J.G. Dumesnil, R. Capoulade, P. Mathieu, M. Senechal, and P. Pibarot Outcome of patients with aortic stenosis, small valve area, and low-flow, low-gradient despite preserved left ventricular ejection fraction J Am Coll Cardiol 60 2012 1259 1267
27. J.G. Dumesnil, P. Pibarot, and B. Carabello Paradoxical low flow and/or low gradient severe aortic stenosis despite preserved left ventricular ejection fraction: implications for diagnosis and treatment Eur Heart J 31 2010 281 289
28. H.I. Michelena, E. Margaryan, and F.A. Miller Inconsistent echocardiographic grading of aortic stenosis: is the left ventricular outflow tract important? Heart 99 2013 921 931
29. D. Messika-Zeitoun, J.M. Serfaty, and E. Brochet Multimodal assessment of the aortic annulus diameter: implications for transcatheter aortic valve implantation J Am Coll Cardiol 55 2010 186 194
30. L. Kadem, J.G. Dumesnil, R. Rieu, L.G. Durand, D. Garcia, and P. Pibarot Impact of systemic hypertension on the assessment of aortic stenosis Heart 91 2005 354 361
31. C. Blais, I.G. Burwash, and G. Mundigler Projected valve area at normal flow rate improves the assessment of stenosis severity in patients with low-flow, low-gradient aortic stenosis: the multicenter TOPAS (Truly or Pseudo-Severe Aortic Stenosis) study Circulation 113 2006 711 721
32. M.A. Clavel, I.G. Burwash, and G. Mundigler Validation of conventional and simplified methods to calculate projected valve area at normal flow rate in patients with low flow, low gradient aortic stenosis: the multicenter TOPAS (True or Pseudo Severe Aortic Stenosis) study J Am Soc Echocardiogr 23 2010 380 386
33. R.A. Nishimura, J.A. Grantham, H.M. Connolly, H.V. Schaff, S.T. Higano, and D.R. Holmes Jr. Low-output, low-gradient aortic stenosis in patients with depressed left ventricular systolic function: the clinical utility of the dobutamine challenge in the catheterization laboratory Circulation 106 2002 809 813
34. Z. Hachicha, J.G. Dumesnil, P. Bogaty, and P. Pibarot Paradoxical low-flow, low-gradient severe aortic stenosis despite preserved ejection fraction is associated with higher afterload and reduced survival Circulation 115 2007 2856 2864
35. P. Lancellotti, J. Magne, and E. Donal Clinical outcome in asymptomatic severe aortic stenosis: insights from the new proposed aortic stenosis grading classification J Am Coll Cardiol 59 2012 235 243
36. J. Adda, C. Mielot, and R. Giorgi Low-flow, low-gradient severe aortic stenosis despite normal ejection fraction is associated with severe left ventricular dysfunction as assessed by speckle-tracking echocardiography: a multicenter study Circ Cardiovasc Imaging 5 2012 27 35
37. M.A. Clavel, P.V. Ennezat, and S. Marechaux Stress echocardiography to assess stenosis severity and predict outcome in patients with paradoxical low-flow, low-gradient aortic stenosis and preserved LVEF J Am Coll Cardiol Img 6 2013 175 183
38. R.R. Makkar, G.P. Fontana, and H. Jilaihawi Transcatheter aortic-valve replacement for inoperable severe aortic stenosis N Engl J Med 366 2012 1696 1704