Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype

American Journal of Respiratory and Critical Care Medicine

Volumn 186, Issue 5, 2012, Pages 404-411

  Lugogo, Njira L ^a   Hollingsworth, John W ^a   Howell, Druhan L ^b   Que, Loretta G ^a   Francisco, Dave ^a   Church, Tony D ^a   Potts Kant, Erin N ^a   Ingram, Jennifer L ^a   Wang, Ying ^a   Jung, Sin Ho ^a   Kraft, Monica ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Environmental lung disease; Innate immunity; Leptin; Lipopolysaccharide; Tumor necrosis factor

Indexed keywords

ADIPOCYTOKINE; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; LEPTIN; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADULT; AGED; ARTICLE; ASTHMA; BODY MASS; BRONCHOSCOPY; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MALE; OBESITY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; ANALYSIS OF VARIANCE; ASTHMA; BIOLOGICAL MARKERS; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOSCOPY; CASE-CONTROL STUDIES; CELLS, CULTURED; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; LEPTIN; LINEAR MODELS; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; MALE; MIDDLE AGED; OBESITY; OVERWEIGHT; PHENOTYPE; YOUNG ADULT;

EID: 84865824614     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201109-1671OC     Document Type: Article

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