Nonsterile glove use in addition to hand hygiene to prevent late-onset infection in preterm infants: Randomized clinical trial

JAMA Pediatrics

Volumn 168, Issue 10, 2014, Pages 909-916

  Kaufman, David A ^a   Blackman, Amy ^a   Conaway, Mark R ^a   Sinkin, Robert A ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAPENEM DERIVATIVE; CEPHALOSPORIN DERIVATIVE; CORTICOSTEROID DERIVATIVE; FLUCONAZOLE; HISTAMINE H2 RECEPTOR ANTAGONIST; PROTON PUMP INHIBITOR;

ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL COLONIZATION; CATHETER INFECTION; CENTRAL VENOUS CATHETER; CONTROLLED STUDY; CORTICOSTEROID THERAPY; FEMALE; GASTROSCHISIS; GESTATIONAL AGE; GLOVE; HAND WASHING; HUMAN; INFANT; INFECTION CONTROL; INFECTION PREVENTION; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NECROTIZING ENTEROCOLITIS; NEWBORN; NEWBORN INFECTION; NEWBORN INTENSIVE CARE; NONSTERILE GLOVE; PERIPHERAL VENOUS CATHETER; PREMATURITY; PROPHYLAXIS; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; URINARY TRACT INFECTION; VANCOMYCIN RESISTANT ENTEROCOCCUS; COMPARATIVE STUDY; CROSS INFECTION; INFANT, PREMATURE, DISEASES; MULTIMODALITY CANCER THERAPY; PROCEDURES; SURGICAL GLOVE; TREATMENT OUTCOME;

COMBINED MODALITY THERAPY; CROSS INFECTION; FEMALE; GLOVES, SURGICAL; HAND HYGIENE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; INFECTION CONTROL; MALE; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84908004786     PISSN: 21686203     EISSN: 21686211     Source Type: Journal    
DOI: 10.1001/jamapediatrics.2014.953     Document Type: Article

References (33)

1. Stoll BJ, Hansen NI, Adams-Chapman I, et al; National Institute of Child Health and Human Development Neonatal Research Network. Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infection. JAMA. 2004;292(19): 2357-2365.
2. Holman RC, Stoll BJ, Curns AT, Yorita KL, Steiner CA, Schonberger LB. Necrotising enterocolitis hospitalisations among neonates in the United States. Paediatr Perinat Epidemiol. 2006;20(6): 498-506.
3. Geffers C, Baerwolff S, Schwab F, Gastmeier P. Incidence of healthcare-associated infections in high-risk neonates: results from the German surveillance system for very-low-birthweight infants. J Hosp Infect. 2008;68(3):214-221.
4. Stoll BJ, Hansen NI, Bell EF, et al; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network. Pediatrics. 2010;126(3):443-456.
5. Goldmann D. System failure versus personal accountability: the case for clean hands. N Engl J Med. 2006;355(2):121-123.
6. Larson E, Silberger M, Jakob K, et al. Assessment of alternative hand hygiene regimens to improve skin health among neonatal intensive care unit nurses. Heart Lung. 2000;29(2):136-142.
7. Cohen B, Saiman L, Cimiotti J, Larson E. Factors associated with hand hygiene practices in two neonatal intensive care units. Pediatr Infect Dis J. 2003;22(6):494-499.
8. Boyce JM, Pittet D; Healthcare Infection Control Practices Advisory Committee; HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force; Society for Healthcare Epidemiology of America/Association for Professionals in Infection Control/Infectious Diseases Society of America. Guideline for hand hygiene in health-care settings: recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. MMWR Recomm Rep. 2002;51(RR-16):1-45.
9. Kaufman D, Fairchild KD. Clinical microbiology of bacterial and fungal sepsis in very-low-birth-weight infants. Clin Microbiol Rev. 2004;17(3):638-680.
10. Pessoa-Silva CL, Dharan S, Hugonnet S, et al. Dynamics of bacterial hand contamination during routine neonatal care. Infect Control Hosp Epidemiol. 2004;25(3):192-197.
11. Tenorio AR, Badri SM, Sahgal NB, et al. Effectiveness of gloves in the prevention of hand carriage of vancomycin-resistant enterococcus species by health care workers after patient care. Clin Infect Dis. 2001;32(5):826-829.
12. McFarland LV, Mulligan ME, Kwok RY, Stamm WE. Nosocomial acquisition of Clostridium difficile infection. N Engl J Med. 1989;320(4):204-210.
13. Ng PC,Wong HL, Lyon DJ, et al. Combined use of alcohol hand rub and gloves reduces the incidence of late onset infection in very low birthweight infants. Arch Dis Child Fetal Neonatal Ed. 2004;89(4):F336-F340.
14. Yin J, Schweizer ML, Herwaldt LA, Pottinger JM, Perencevich EN. Benefits of universal gloving on hospital-acquired infections in acute care pediatric units. Pediatrics. 2013;131(5):e1515-e1520. doi:10.1542/peds.2012-3389.
15. Kilbride HW, Wirtschafter DD, Powers RJ, Sheehan MB. Implementation of evidence-based potentially better practices to decrease nosocomial infections. Pediatrics. 2003;111(4 pt 2):e519-e533.
16. Kilbride HW, Powers R, Wirtschafter DD, et al. Evaluation and development of potentially better practices to prevent neonatal nosocomial bacteremia. Pediatrics. 2003;111(4, pt 2):e504-e518.
17. Schelonka RL, Scruggs S, Nichols K, Dimmitt RA, CarloWA. Sustained reductions in neonatal nosocomial infection rates following a comprehensive infection control intervention. J Perinatol. 2006;26(3):176-179.
18. Pessoa-Silva CL, Hugonnet S, Pfister R, et al. Reduction of health care-associated infection risk in neonates by successful hand hygiene promotion. Pediatrics. 2007;120(2):e382-e390.
19. World Health Organization.World Health Organization Guidelines on Hand Hygiene in Health Care. Geneva, Switzerland:Word Health Organization; 2009.
20. Stoll BJ, Hansen N, Fanaroff AA, et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics. 2002;110(2, pt 1): 285-291.
21. Fanaroff AA, Korones SB,Wright LL, et al; The National Institute of Child Health and Human Development Neonatal Research Network. Incidence, presenting features, risk factors and significance of late onset septicemia in very low birth weight infants. Pediatr Infect Dis J. 1998;17(7): 593-598.
22. BellMJ, Ternberg JL, Feigin RD, et al. Neonatal necrotizing enterocolitis: therapeutic decisions based upon clinical staging. Ann Surg. 1978;187(1):1-7.
23. Alshaikh B, YeeW, Lodha A, Henderson E, Yusuf K, Sauve R. Coagulase-negative staphylococcus sepsis in preterm infants and long-term neurodevelopmental outcome. J Perinatol. 2014;34(2):125-129.
24. Alshaikh B, Yusuf K, Sauve R. Neurodevelopmental outcomes of very low birth weight infants with neonatal sepsis: systematic review and meta-analysis. J Perinatol. 2013;33(7): 558-564.
25. Shah DK, Doyle LW, Anderson PJ et al. Adverse neurodevelopment in preterm infants with postnatal sepsis or necrotizing enterocolitis is mediated by white matter abnormalities on magnetic resonance imaging at term. J Pediatr. 2008;153(2):170-175.e1. doi:10.1016/j.jpeds.2008.02.033.
26. Bauer S, Eliakim A, Pomeranz A, et al. Urinary tract infection in very low birth weight preterm infants. Pediatr Infect Dis J. 2003;22(5):426-430.
27. Miettinen O, Nurminen M. Comparative analysis of two rates. Stat Med. 1985;4(2): 213-226.
28. Vermont Oxford Network Database. Nightingale internet reporting system. Burlington: Vermont Oxford Network; 2008-2011. https://nightingale.vtoxford.org. Accessed July 3, 2014.
29. Milstone AM, Elward A, Song X, et al; Pediatric SCRUB Trial Study Group. Daily chlorhexidine bathing to reduce bacteraemia in critically ill children: a multicentre, cluster-randomised, crossover trial. Lancet. 2013;381(9872):1099-1106.
30. HuskinsWC, Huckabee CM, O'Grady NP, et al; STAR∗ICU Trial Investigators. Intervention to reduce transmission of resistant bacteria in intensive care. N Engl J Med. 2011;364(15):1407-1418.
31. Jain R, Kralovic SM, Evans ME, et al. Veterans Affairs initiative to prevent methicillin-resistant Staphylococcus aureus infections. N Engl J Med. 2011;364(15):1419-1430.
32. Rutter N. Clinical consequences of an immature barrier. Semin Neonatol. 2000;5(4):281-287.
33. Lemyre B, XiuW, Bouali NR, et al. A decrease in the number of cases of necrotizing enterocolitis associated with the enhancement of infection prevention and control measures during a Staphylococcus aureus outbreak in a neonatal intensive care unit. Infect Control Hosp Epidemiol. 2012;33(1):29-33.