Novel inhibitory effects of cardamonin on thromboxane A2-induced scratching response: Blocking of Gh/transglutaminase-2 binding to thromboxane A2 receptor

Pharmacology Biochemistry and Behavior

Volumn 126, Issue , 2014, Pages 131-135

  Park, Mi Kyung ^a   Choi, Jin Kyu ^b   Kim, Hyun Ji ^a   Nakahata, Norimichi ^c   Lim, Kyung Min ^d   Kim, Soo Youl ^e   Lee, Chang Hoon ^a  

^a Dongguk University   (South Korea)

^b Seoul National University   (South Korea)

^c TOHOKU UNIVERSITY   (Japan)

^d Ewha Womans University   (South Korea)

^e National Cancer Center   (South Korea)

Author keywords

Antipruritic; Cardamonin; Gh Transglutaminase 2; Itching; TXA2 receptor; U46619

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ANTIPRURITIC AGENT; CARDAMONIN; PLANT MEDICINAL PRODUCT; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR; UNCLASSIFIED DRUG; CHALCONE DERIVATIVE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDRAZINE DERIVATIVE; PROTEIN BINDING; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; TRITIUM;

A549 CELL LINE; ALPINIA; ALPINIA KATSUMADAI; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG COMPETITION; EMBRYO; ENZYME BINDING; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PRURITUS; RECEPTOR BINDING; SCRATCHING; SIGNAL TRANSDUCTION; THROMBOCYTE; TREATMENT RESPONSE; ANIMAL; ANIMAL BEHAVIOR; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; RADIOASSAY;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; BEHAVIOR, ANIMAL; BLOOD PLATELETS; CELL LINE; CHALCONES; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEINS; HUMANS; HYDRAZINES; MICE; PROTEIN BINDING; PRURITUS; RADIOLIGAND ASSAY; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; THROMBOXANE A2; TRANSGLUTAMINASES; TRITIUM;

EID: 84907979169     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2014.09.011     Document Type: Article

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