Identifying roles of " Jun-Chen-Zuo-Shi" component herbs of QiShenYiQi formula in treating acute myocardial ischemia by network pharmacology

Chinese Medicine (United Kingdom)

Volumn 9, Issue 1, 2014, Pages

  Wu, Leihong ^a   Wang, Yi ^a   Li, Zheng ^b   Zhang, Boli ^b   Cheng, Yiyu ^a   Fan, Xiaohui ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHINESE DRUG; HERBACEOUS AGENT; JUN CHEN ZUO SHI; QISHENYIQI; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTRAGALUS MEMBRANACEUS; DALBERGIA; DALBERGIA SISSOO; HEART MUSCLE ISCHEMIA; NONHUMAN; PANAX NOTOGINSENG; PROTEIN PROTEIN INTERACTION; RAT; SALVIA; SALVIA MILTIORRRHIZA;

EID: 84907954937     PISSN: None     EISSN: 17498546     Source Type: Journal    
DOI: 10.1186/1749-8546-9-24     Document Type: Article

References (33)

1. Barabasi AL, Gulbahce N, Loscalzo J. Network medicine: a network-based approach to human disease. Nat Rev Genet 2011, 12(1):56-68. 10.1038/nrg2918, 3140052, 21164525.
2. Yang J, Li Z, Fan X, Cheng Y. A Three Step Network Based Approach (TSNBA) to finding disease molecular signature and key regulators: a case study of IL-1 and TNF-Alpha stimulated inflammation. PLoS One 2014, 9(4):e94360. 10.1371/journal.pone.0094360, 3991618, 24747419.
3. Clercq ED. Perspectives of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection. Farmaco 1999, 54(2):26-45.
4. Xiao S, Luo K, Wen X, Fan X, Cheng Y. A pre-classification strategy for identification of compounds in traditional Chinese medicine analogous formulas by high-performance liquid chromatography-Mass spectrometry. J Pharm Biomed Anal 2014, 92:82-89.
5. Wang L, Zhou GB, Liu P, Song JH, Liang Y, Yan XJ, Xu F, Wang BS, Mao JH, Shen ZX, Chen SJ, Chen Z. Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. Proc Natl Acad Sci U S A 2008, 105(12):4826-4831. 10.1073/pnas.0712365105, 2290784, 18344322.
6. Li S, Zhang B, Jiang D, Wei Y, Zhang N. Herb network construction and co-module analysis for uncovering the combination rule of traditional Chinese herbal formulae. BMC Bioinformatics 2010, 11(Suppl 11):S6.
7. Li S, Zhang B, Zhang N. Network target for screening synergistic drug combinations with application to traditional Chinese medicine. BMC Syst Biol 2011, 5(Suppl 1):S10.
8. Liang X, Li H, Li S. A novel network pharmacology approach to analyse traditional herbal formulae: the Liu-Wei-Di-Huang pill as a case study. Mol Biosyst 2014, 10(5):1014-1022. 10.1039/c3mb70507b, 24492828.
9. Wang L, Li Z, Shao Q, Li X, Ai N, Zhao X, Fan X. Dissecting active ingredients of Chinese medicine by content-weighted ingredient-target network. Mol Biosyst 2014, 10(7):1905-1911. 10.1039/c3mb70581a, 24781185.
10. Wang L, Li Z, Zhao X, Liu W, Liu Y, Yang J, Li X, Fan X, Cheng Y. A network study of chinese medicine xuesaitong injection to elucidate a complex mode of action with multicompound, multitarget, and multipathway. Evid Based Complement Alternat Med 2013, 2013:652373. 3766588, 24058375.
11. Wu L, Wang Y, Nie J, Fan X, Cheng Y. A network pharmacology approach to evaluating the efficacy of Chinese medicine using genome-wide transcriptional expression data. Evid Based Complement Alternat Med 2013, 2013:8.
12. Zhang YF, Shi PY, Yao H, Shao Q, Fan XH. Metabolite profiling and pharmacokinetics of herbal compounds following oral administration of a cardiovascular multi-herb medicine (Qishen Yiqi Pills) in rat. Curr Drug Metab 2012, 13(5):510-523. 10.2174/1389200211209050510, 22292791.
13. Li X, Wu L, Liu W, Jin Y, Chen Q, Wang L, Fan X, Li Z, Cheng Y. A network pharmacology study of Chinese medicine QiShenYiQi to reveal its underlying multi-compound, multi-target, multi-pathway mode of action. PLoS One 2014, 9(5):e95004. 10.1371/journal.pone.0095004, 4015902, 24817581.
14. Shang H, Dai G, Hang J, Xiang Y, Wang Y, Zhang J, Du W, Mao J, Yao C, Weng W, Wen TC. Myocardial infarction secondary prevention study (MISPS). Geriatr Cardiol 2006, 3(2):116-119.
15. Zhang L, Wang Y, Yu L, Liu L, Qu H, Wang Y, Gao X, Zhang B, Cheng Y. QI-SHEN-YI-QI accelerates angiogenesis after myocardial infarction in rats. Int J Cardiol 2009, 143(1):105-109.
16. Hong C, Wang Y, Lou J, Liu Q, Qu H, Cheng Y. Analysis of myocardial proteomic alteration after Qishenyiqi formula treatment in acute infarcted rat hearts. Zhongguo Zhong Yao Za Zhi 2009, 34(8):1018-1021.
17. Pfeffer MA, Pfeffer JM, Fishbein MC, Fletcher PJ, Spadaro J, Kloner RA, Braunwald E. Myocardial infarct size and ventricular function in rats. Circ Res 1979, 44(4):503-512. 10.1161/01.RES.44.4.503, 428047.
18. Yamaguchi F, Sanbe A, Takeo S. Cardiac sarcoplasmic reticular function in rats with chronic heart failure following myocardial infarction. J Mol Cell Cardiol 1997, 29(2):753-763. 10.1006/jmcc.1996.0319, 9140832.
19. Wu L, Li X, Yang J, Liu Y, Fan X, Cheng Y. CHD@ZJU: a knowledgebase providing network-based research platform on coronary heart disease. Database 2013, 2013:bat047. 3697781, 23818526.
20. Dwinell MR, Worthey EA, Shimoyama M, Bakir-Gungor B, DePons J, Laulederkind S, Lowry T, Nigram R, Petri V, Smith J, Stoddard A, Twigger SN, Jacob HJ. The Rat Genome Database 2009: variation, ontologies and pathways. Nucleic Acids Res 2009, 37(Database issue):D744-D749. 2686558, 18996890.
21. Keshava Prasad TS, Goel R, Kandasamy K, Keerthikumar S, Kumar S, Mathivanan S, Telikicherla D, Raju R, Shafreen B, Venugopal A, Balakrishnan L, Marimuthu A, Banerjee S, Somanathan DS, Sebastian A, Rani S, Ray S, Kishore CJH, Kanth S, Ahmed M, Kashyap MK, Mohmood R, Ramachandra YL, Krishna V, Rahiman BA, Mohan S, Ranganathan P, Ramabadran S, Chaerkady R, Pandey A. Human protein reference database-2009 update. Nucleic Acids Res 2009, 37(Database issue):D767-D772. 2686490, 18988627.
22. Stark C, Breitkreutz BJ, Reguly T, Boucher L, Breitkreutz A, Tyers M. BioGRID: a general repository for interaction datasets. Nucleic Acids Res 2006, 34(Database issue):D535-D539. 1347471, 16381927.
23. Smoot ME, Ono K, Ruscheinski J, Wang PL, Ideker T. Cytoscape 2.8: new features for data integration and network visualization. Bioinformatics 2011, 27(3):431-432. 10.1093/bioinformatics/btq675, 3031041, 21149340.
24. Fang H, Harris SC, Su Z, Chen M, Qian F, Shi L, Perkins R, Tong W. ArrayTrack: An FDA and public genomic tool. Methods Mol Biol 2009, 563:379-398. 10.1007/978-1-60761-175-2_20, 19597796.
25. Bohr DF, Webb RC. Vascular smooth muscle function and its changes in hypertension. Am J Med 1984, 77(4A):3-16.
26. Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001, 2(8):675-680. 10.1038/90609, 11477402.
27. Krijnen PAJ, Nijmeijer R, Meijer CJLM, Visser CA, Hack CE, Niessen HWM. Apoptosis in myocardial ischaemia and infarction. J Clin Pathol 2002, 55(11):801-811. 10.1136/jcp.55.11.801, 1769793, 12401816.
28. Chiarugi V, Magnelli L, Cinelli M. Complex interplay among apoptosis factors: RB, p53, E2F, TGF-beta, cell cycle inhibitors and the bcl2 gene family. Pharmacol Res 1997, 35(4):257-261. 10.1006/phrs.1997.0140, 9264039.
29. Gui D, Guo Y, Wang F, Liu W, Chen J, Chen Y, Huang J, Wang N. Astragaloside IV, a novel antioxidant, prevents glucose-induced Podocyte Apoptosis In Vitro and In Vivo. PLoS One 2012, 7(6):e39824. 10.1371/journal.pone.0039824, 3382154, 22745830.
30. Zhao Z, Wang W, Wang F, Zhao K, Han Y, Xu W, Tang L. Effects of Astragaloside IV on heart failure in rats. Chin Med 2009, 4:6. 10.1186/1749-8546-4-6, 2674594, 19338675.
31. Bujak M, Frangogiannis NG. The role of TGF-β Signaling in Myocardial Infarction and Cardiac Remodeling. Cardiovasc Res 2007, 74(2):184-195. 10.1016/j.cardiores.2006.10.002, 1924687, 17109837.
32. Kuerbitz SJ, Plunkett BS, Walsh WV, Kastan MB. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci 1992, 89(16):7491-7495. 10.1073/pnas.89.16.7491, 49736, 1323840.
33. Keane MP, Strieter RM. Chemokine signaling in inflammation. Crit Care Med 2000, 28(4):N13-N26.