Upregulation of eIF5B controls cell-cycle arrest and specific developmental stages

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 41, 2014, Pages E4315-E4322

  Lee, Sooncheol ^a   Truesdell, Samuel S ^a   Bukhari, Syed I A ^a   Lee, Ju Huck ^a   LeTonqueze, Olivier ^a   Vasudevan, Shobha ^a   Steitz, Joan A ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Early serum starvation; EIF2 phosphorylation; Embryonic stem cells

Indexed keywords

CULTURE MEDIUM; EUKARYOTIC INITIATION FACTOR-5B; INITIATION FACTOR; INITIATION FACTOR 2; METHIONINE TRANSFER RNA;

ANIMAL; CELL CYCLE CHECKPOINT; CELL LINE; CELL SURVIVAL; CULTURE MEDIUM; CYTOLOGY; EMBRYONIC STEM CELL; GENETICS; HUMAN; METABOLISM; MOUSE; OOCYTE; PHOSPHORYLATION; PROTEIN SYNTHESIS; UPREGULATION; XENOPUS LAEVIS;

ANIMALS; CELL CYCLE CHECKPOINTS; CELL LINE; CELL SURVIVAL; CULTURE MEDIA, SERUM-FREE; EMBRYONIC STEM CELLS; EUKARYOTIC INITIATION FACTOR-2; EUKARYOTIC INITIATION FACTORS; HUMANS; MICE; OOCYTES; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RNA, TRANSFER, MET; UP-REGULATION; XENOPUS LAEVIS;

EID: 84907925008     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1320477111     Document Type: Article

References (31)

1. Jackson RJ, Hellen CU, Pestova TV (2010) The mechanism of eukaryotic translation initiation and principles of its regulation. Nat Rev Mol Cell Biol 11(2):113-127.
2. Sonenberg N, Hinnebusch AG (2009) Regulation of translation initiation in eukaryotes: Mechanisms and biological targets. Cell 136(4):731-745.
3. Gray NK, Wickens M (1998) Control of translation initiation in animals. Annu Rev Cell Dev Biol 14:399-458.
4. Radford HE, Meijer HA, de Moor CH (2008) Translational control by cytoplasmic polyadenylation in Xenopus oocytes. Biochim Biophys Acta 1779(4):217-229.
5. Mortensen RD, Serra M, Steitz JA, Vasudevan S (2011) Posttranscriptional activation of gene expression in Xenopus laevis oocytes by microRNA-protein complexes (microRNPs). Proc Natl Acad Sci USA 108(20):8281-8286.
6. Sampath P, et al. (2008)A hierarchical network controls protein translation duringmurine embryonic stem cell self-renewal and differentiation. Cell Stem Cell 2(5):448-460.
7. Ingolia NT, Lareau LF, Weissman JS (2011) Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell 147(4): 789-802.
8. Taieb F, Thibier C, Jessus C (1997) On cyclins, oocytes, and eggs. Mol Reprod Dev 48(3): 397-411.
9. Coller HA, Sang L, Roberts JM (2006) A new description of cellular quiescence. PLoS Biol 4(3):e83.
10. Loayza-Puch F, et al. (2013) p53 induces transcriptional and translational programs to suppress cell proliferation and growth. Genome Biol 14(4):R32.
11. Allen GS, Frank J (2007) Structural insights on the translation initiation complex: Ghosts of a universal initiation complex. Mol Micro biol 63(4):941-950.
12. Terenin IM, Dmitriev SE, Andreev DE, Shatsky IN (2008) Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2. Nat Struct Mol Biol 15(8):836-841.
13. Shin BS, et al. (2011) Structural integrity of α-helix H12 in translation initiation factor eIF5B is critical for 80S complex stability. RNA 17(4):687-696.
14. Pestova TV, et al. (2000) The joining of ribosomal subunits in eukaryotes requires eIF5B. Nature 403(6767):332-335.
15. Strunk BS, Novak MN, Young CL, Karbstein K (2012) A translation-like cycle is a quality control checkpoint for maturing 40S ribosome subunits. Cell 150(1):111-121.
16. Lebaron S, et al. (2012) Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits. Nat Struct Mol Biol 19(8):744-753.
17. Thakor N, Holcik M (2012) IRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress. Nucleic Acids Res 40(2):541-552.
18. White JP, Reineke LC, Lloyd RE (2011) Poliovirus switches to an eIF2-independent mode of translation during infection. J Virol 85(17):8884-8893.
19. Pestova TV, de Breyne S, Pisarev AV, Abaeva IS, Hellen CU (2008) eIF2-dependent and eIF2-independent modes of initiation on the CSFV IRES: A common role of domain II. EMBO J 27(7):1060-1072.
20. Carrera P, et al. (2000) VASA mediates translation through interaction with a Drosophila yIF2 homolog. Mol Cell 5(1):181-187.
21. Zeenko VV, et al. (2008) An efficient in vitro translation system from mammalian cells lacking the translational inhibition caused by eIF2 phosphorylation. RNA 14(3): 593-602.
22. Shin BS, et al. (2011) Initiation factor eIF2γ promotes eIF2-GTP-Met-tRNAi(Met) ternary complex binding to the 40S ribosome. Nat Struct Mol Biol 18(11):1227-1234.
23. De Smedt V, et al. (2002) Thr-161 phosphorylation of monomeric Cdc2. Regulation by protein phosphatase 2C in Xenopus oocytes. J Biol Chem 277(32):28592-28600.
24. Wang X, Yang P (2008) In vitro differentiation of mouse embryonic stem (mES) cells using the hanging drop method. J Vis Exp (17):825, 10.3791/825.
25. Balachandran S, Barber GN (2004) Defective translational control facilitates vesicular stomatitis virus oncolysis. Cancer Cell 5(1):51-65.
26. Elsby R, et al. (2011) The alpha subunit of eukaryotic initiation factor 2B (eIF2B) is required for eIF2-mediated translational suppression of vesicular stomatitis virus. J Virol 85(19):9716-9725.
27. Khaleghpour K, Pyronnet S, Gingras AC, Sonenberg N (1999) Translational homeostasis: Eukaryotic translation initiation factor 4E control of 4E-binding protein 1 and p70 S6 kinase activities. Mol Cell Biol 19(6):4302-4310.
28. Galicia-Vázquez G, Cencic R, Robert F, Agenor AQ, Pelletier J (2012) A cellular response linking eIF4AI activity to eIF4AII transcription. RNA 18(7):1373-1384.
29. Montine KS, Henshaw EC (1989) Serum growth factors cause rapid stimulation of protein synthesis and dephos phorylation of eIF-2 in serum deprived Ehrlich cells Biochimica et Biophysica Acta (BBA). Molecular Cell Research 1014(3):282-288.
30. Loughran G, Sachs MS, Atkins JF, Ivanov IP (2012) Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5. Nucleic Acids Res 40(7): 2898-2906.
31. Koritzinsky M, et al. (2006) Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control. EMBO J 25(5): 1114-1125.