-
1
-
-
80755145883
-
Regulation of placenta growth factor by microRNA-125b in hepatocellular cancer
-
Alpini G, Glaser SS, Zhang JP, Francis H, Han Y, Gong J, Stokes A, Francis T, Hughart N, and Hubble L et al. (2011) Regulation of placenta growth factor by microRNA-125b in hepatocellular cancer. J Hepatol 55:1339-1345.
-
(2011)
J Hepatol
, vol.55
, pp. 1339-1345
-
-
Alpini, G.1
Glaser, S.S.2
Zhang, J.P.3
Francis, H.4
Han, Y.5
Gong, J.6
Stokes, A.7
Francis, T.8
Hughart, N.9
Hubble, L.10
-
2
-
-
79251567720
-
DNA methylation of the first exon is tightly linked to transcriptional silencing
-
Brenet F, Moh M, Funk P, Feierstein E, Viale AJ, Socci ND, and Scandura JM (2011) DNA methylation of the first exon is tightly linked to transcriptional silencing. PLoS ONE 6:e14524.
-
(2011)
PLoS ONE
, vol.6
, pp. e14524
-
-
Brenet, F.1
Moh, M.2
Funk, P.3
Feierstein, E.4
Viale, A.J.5
Socci, N.D.6
Scandura, J.M.7
-
3
-
-
80052223077
-
MicroRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer
-
Buffa FM, Camps C, Winchester L, Snell CE, Gee HE, Sheldon H, Taylor M, Harris AL, and Ragoussis J (2011) MicroRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Res 71:5635-5645.
-
(2011)
Cancer Res
, vol.71
, pp. 5635-5645
-
-
Buffa, F.M.1
Camps, C.2
Winchester, L.3
Snell, C.E.4
Gee, H.E.5
Sheldon, H.6
Taylor, M.7
Harris, A.L.8
Ragoussis, J.9
-
4
-
-
78751483761
-
MiR-200b targets Ets-1 and is downregulated by hypoxia to induce angiogenic response of endothelial cells
-
Chan YC, Khanna S, Roy S, and Sen CK (2011) miR-200b targets Ets-1 and is downregulated by hypoxia to induce angiogenic response of endothelial cells. J Biol Chem 286:2047-2056.
-
(2011)
J Biol Chem
, vol.286
, pp. 2047-2056
-
-
Chan, Y.C.1
Khanna, S.2
Roy, S.3
Sen, C.K.4
-
5
-
-
48549091046
-
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis
-
Datta J, Kutay H, Nasser MW, Nuovo GJ, Wang B, Majumder S, Liu CG, Volinia S, Croce CM, and Schmittgen TD et al. (2008) Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res 68: 5049-5058.
-
(2008)
Cancer Res
, vol.68
, pp. 5049-5058
-
-
Datta, J.1
Kutay, H.2
Nasser, M.W.3
Nuovo, G.J.4
Wang, B.5
Majumder, S.6
Liu, C.G.7
Volinia, S.8
Croce, C.M.9
Schmittgen, T.D.10
-
6
-
-
33748302836
-
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
-
Dews M, Homayouni A, Yu D, Murphy D, Sevignani C, Wentzel E, Furth EE, Lee WM, Enders GH, and Mendell JT et al. (2006) Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet 38:1060-1065.
-
(2006)
Nat Genet
, vol.38
, pp. 1060-1065
-
-
Dews, M.1
Homayouni, A.2
Yu, D.3
Murphy, D.4
Sevignani, C.5
Wentzel, E.6
Furth, E.E.7
Lee, W.M.8
Enders, G.H.9
Mendell, J.T.10
-
7
-
-
77952299722
-
MiR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma
-
Furuta M, Kozaki KI, Tanaka S, Arii S, Imoto I, and Inazawa J (2010) miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis 31:766-776.
-
(2010)
Carcinogenesis
, vol.31
, pp. 766-776
-
-
Furuta, M.1
Kozaki, K.I.2
Tanaka, S.3
Arii, S.4
Imoto, I.5
Inazawa, J.6
-
8
-
-
5444227862
-
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach
-
Gius D, Cui H, Bradbury CM, Cook J, Smart DK, Zhao S, Young L, Brandenburg SA, Hu Y, and Bisht KS et al. (2004) Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. Cancer Cell 6:361-371.
-
(2004)
Cancer Cell
, vol.6
, pp. 361-371
-
-
Gius, D.1
Cui, H.2
Bradbury, C.M.3
Cook, J.4
Smart, D.K.5
Zhao, S.6
Young, L.7
Brandenburg, S.A.8
Hu, Y.9
Bisht, K.S.10
-
9
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D and Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
10
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, Xue W, Zender L, Magnus J, and Ridzon D et al. (2007) A microRNA component of the p53 tumour suppressor network. Nature 447:1130-1134.
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
De Stanchina, E.4
Xuan, Z.5
Liang, Y.6
Xue, W.7
Zender, L.8
Magnus, J.9
Ridzon, D.10
-
11
-
-
80053435478
-
Hypomethylation of the hsa-miR-191 locus causes high expression of hsa-mir-191 and promotes the epithelial-to-mesenchymal transition in hepatocellular carcinoma
-
He Y, Cui Y, Wang W, Gu J, Guo S, Ma K, and Luo X (2011) Hypomethylation of the hsa-miR-191 locus causes high expression of hsa-mir-191 and promotes the epithelial-to-mesenchymal transition in hepatocellular carcinoma. Neoplasia 13: 841-853.
-
(2011)
Neoplasia
, vol.13
, pp. 841-853
-
-
He, Y.1
Cui, Y.2
Wang, W.3
Gu, J.4
Guo, S.5
Ma, K.6
Luo, X.7
-
12
-
-
21044439177
-
Approval summary: Azacitidine for treatment of myelodysplastic syndrome subtypes
-
Kaminskas E, Farrell A, Abraham S, Baird A, Hsieh LS, Lee SL, Leighton JK, Patel H, Rahman A, and Sridhara R et al.; FDA (2005) Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypes. Clin Cancer Res 11: 3604-3608.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3604-3608
-
-
Kaminskas, E.1
Farrell, A.2
Abraham, S.3
Baird, A.4
Hsieh, L.S.5
Lee, S.L.6
Leighton, J.K.7
Patel, H.8
Rahman, A.9
Sridhara, R.10
-
13
-
-
20944450160
-
Combinatorial microRNA target predictions
-
Krek A, Grün D, Poy MN, Wolf R, Rosenberg L, Epstein EJ, MacMenamin P, da Piedade I, Gunsalus KC, and Stoffel M et al. (2005) Combinatorial microRNA target predictions. Nat Genet 37:495-500.
-
(2005)
Nat Genet
, vol.37
, pp. 495-500
-
-
Krek, A.1
Grün, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
Epstein, E.J.6
Macmenamin, P.7
Da Piedade, I.8
Gunsalus, K.C.9
Stoffel, M.10
-
14
-
-
84856241901
-
MicroRNA-mediated drug resistance in breast cancer
-
Kutanzi KR, Yurchenko OV, Beland FA, Checkhun VF, and Pogribny IP (2011) MicroRNA-mediated drug resistance in breast cancer. Clin Epigenetics 2:171-185.
-
(2011)
Clin Epigenetics
, vol.2
, pp. 171-185
-
-
Kutanzi, K.R.1
Yurchenko, O.V.2
Beland, F.A.3
Checkhun, V.F.4
Pogribny, I.P.5
-
15
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee Y, Kim M, Han J, Yeom KH, Lee S, Baek SH, and Kim VN (2004) MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23:4051-4060.
-
(2004)
EMBO J
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Baek, S.H.6
Kim, V.N.7
-
16
-
-
77955970299
-
MicroRNA and cancer
-
Li M, Li J, Ding X, He M, and Cheng SY (2010) microRNA and cancer. AAPS J 12: 309-317.
-
(2010)
AAPS J
, vol.12
, pp. 309-317
-
-
Li, M.1
Li, J.2
Ding, X.3
He, M.4
Cheng, S.Y.5
-
17
-
-
38749105154
-
Recent advances in P-glycoprotein-mediated multidrug resistance reversal mechanisms
-
Li X, Li JP, Yuan HY, Gao X, Qu XJ, Xu WF, and Tang W (2007) Recent advances in P-glycoprotein-mediated multidrug resistance reversal mechanisms. Methods Find Exp Clin Pharmacol 29:607-617.
-
(2007)
Methods Find Exp Clin Pharmacol
, vol.29
, pp. 607-617
-
-
Li, X.1
Li, J.P.2
Yuan, H.Y.3
Gao, X.4
Qu, X.J.5
Xu, W.F.6
Tang, W.7
-
18
-
-
69249096109
-
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
-
Li Y, VandenBoom TG, 2nd, Kong D, Wang Z, Ali S, Philip PA, and Sarkar FH (2009) Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res 69:6704-6712.
-
(2009)
Cancer Res
, vol.69
, pp. 6704-6712
-
-
Li, Y.1
Vandenboom, T.G.2
Kong, D.3
Wang, Z.4
Ali, S.5
Philip, P.A.6
Sarkar, F.H.7
-
19
-
-
33947145218
-
Increased store-operated and 1-oleoyl-2-acetyl-sn-glycerolinduced calcium influx in monocytes is mediated by transient receptor potential canonical channels in human essential hypertension
-
Liu DY, Thilo F, Scholze A, Wittstock A, Zhao ZG, Harteneck C, Zidek W, Zhu ZM, and Tepel M (2007) Increased store-operated and 1-oleoyl-2-acetyl-sn-glycerolinduced calcium influx in monocytes is mediated by transient receptor potential canonical channels in human essential hypertension. J Hypertens 25:799-808.
-
(2007)
J Hypertens
, vol.25
, pp. 799-808
-
-
Liu, D.Y.1
Thilo, F.2
Scholze, A.3
Wittstock, A.4
Zhao, Z.G.5
Harteneck, C.6
Zidek, W.7
Zhu, Z.M.8
Tepel, M.9
-
20
-
-
23044484221
-
Expression profiling of ABC transporters in a drug-resistant breast cancer cell line using AmpArray
-
Liu Y, Peng H, and Zhang JT (2005) Expression profiling of ABC transporters in a drug-resistant breast cancer cell line using AmpArray. Mol Pharmacol 68: 430-438.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 430-438
-
-
Liu, Y.1
Peng, H.2
Zhang, J.T.3
-
21
-
-
84862109179
-
Global microRNA expression profiling of high-risk ER1 breast cancers from patients receiving adjuvant tamoxifen mono-therapy: A DBCG study
-
Lyng MB, Lænkholm AV, Søkilde R, Gravgaard KH, Litman T, and Ditzel HJ (2012) Global microRNA expression profiling of high-risk ER1 breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG study. PLoS ONE 7: e36170.
-
(2012)
PLoS ONE
, vol.7
, pp. e36170
-
-
Lyng, M.B.1
Lænkholm, A.V.2
Søkilde, R.3
Gravgaard, K.H.4
Litman, T.5
Ditzel, H.J.6
-
22
-
-
84867061497
-
Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells
-
Ma X, Cai Y, He D, Zou C, Zhang P, Lo CY, Xu Z, Chan FL, Yu S, and Chen Y et al. (2012) Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells. Proc Natl Acad Sci USA 109:16282-16287.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 16282-16287
-
-
Ma, X.1
Cai, Y.2
He, D.3
Zou, C.4
Zhang, P.5
Lo, C.Y.6
Xu, Z.7
Chan, F.L.8
Yu, S.9
Chen, Y.10
-
23
-
-
84899626532
-
Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance
-
Ma X, Chen Z, Hua D, He D, Wang L, Zhang P, Wang J, Cai Y, Gao C, and Zhang X et al. (2014) Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance. Proc Natl Acad Sci U S A 111: 6389-6394.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 6389-6394
-
-
Ma, X.1
Chen, Z.2
Hua, D.3
He, D.4
Wang, L.5
Zhang, P.6
Wang, J.7
Cai, Y.8
Gao, C.9
Zhang, X.10
-
24
-
-
79958176952
-
Elevated expression of CUEDC2 protein confers endocrine resistance in breast cancer
-
Pan X, Zhou T, Tai YH, Wang C, Zhao J, Cao Y, Chen Y, Zhang PJ, Yu M, and Zhen C et al. (2011) Elevated expression of CUEDC2 protein confers endocrine resistance in breast cancer. Nat Med 17:708-714.
-
(2011)
Nat Med
, vol.17
, pp. 708-714
-
-
Pan, X.1
Zhou, T.2
Tai, Y.H.3
Wang, C.4
Zhao, J.5
Cao, Y.6
Chen, Y.7
Zhang, P.J.8
Yu, M.9
Zhen, C.10
-
25
-
-
65349162096
-
Let-7 and miR-200 microRNAs: Guardians against pluripotency and cancer progression
-
Peter ME (2009) Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression. Cell Cycle 8:843-852.
-
(2009)
Cell Cycle
, vol.8
, pp. 843-852
-
-
Peter, M.E.1
-
26
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak K and Weinberg RA (2009) Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 9:265-273.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
27
-
-
12344308462
-
Estrogen receptor-negative breast carcinomas: A review of morphology and immunophenotypical analysis
-
Putti TC, El-Rehim DM, Rakha EA, Paish CE, Lee AH, Pinder SE, and Ellis IO (2005) Estrogen receptor-negative breast carcinomas: a review of morphology and immunophenotypical analysis. Mod Pathol 18:26-35.
-
(2005)
Mod Pathol
, vol.18
, pp. 26-35
-
-
Putti, T.C.1
El-Rehim, D.M.2
Rakha, E.A.3
Paish, C.E.4
Lee, A.H.5
Pinder, S.E.6
Ellis, I.O.7
-
28
-
-
33745248430
-
MicroRNA target predictions in animals
-
Rajewsky N (2006) microRNA target predictions in animals. Nat Genet 38 (Suppl): S8-S13.
-
(2006)
Nat Genet
, vol.38
, pp. S8-S13
-
-
Rajewsky, N.1
-
29
-
-
6344281172
-
Identification of mammalian microRNA host genes and transcription units
-
Rodriguez A, Griffiths-Jones S, Ashurst JL, and Bradley A (2004) Identification of mammalian microRNA host genes and transcription units. Genome Res 14 (10A): 1902-1910.
-
(2004)
Genome Res
, vol.14
, Issue.10 A
, pp. 1902-1910
-
-
Rodriguez, A.1
Griffiths-Jones, S.2
Ashurst, J.L.3
Bradley, A.4
-
30
-
-
33749598345
-
Epigenetic activation of tumor suppressor microRNAs in human cancer cells
-
Saito Y and Jones PA (2006) Epigenetic activation of tumor suppressor microRNAs in human cancer cells. Cell Cycle 5:2220-2222.
-
(2006)
Cell Cycle
, vol.5
, pp. 2220-2222
-
-
Saito, Y.1
Jones, P.A.2
-
31
-
-
77953022034
-
Implication of microRNAs in drug resistance for designing novel cancer therapy
-
Sarkar FH, Li Y, Wang Z, Kong D, and Ali S (2010) Implication of microRNAs in drug resistance for designing novel cancer therapy. Drug Resist Updat 13:57-66.
-
(2010)
Drug Resist Updat
, vol.13
, pp. 57-66
-
-
Sarkar, F.H.1
Li, Y.2
Wang, Z.3
Kong, D.4
Ali, S.5
-
32
-
-
84886443752
-
MicroRNAs in the tumour microenvironment: Big role for small players
-
Soon P and Kiaris H (2013) MicroRNAs in the tumour microenvironment: big role for small players. Endocr Relat Cancer 20:R257-R267.
-
(2013)
Endocr Relat Cancer
, vol.20
, pp. R257-R267
-
-
Soon, P.1
Kiaris, H.2
-
33
-
-
71149113328
-
Decitabine treatment of patients with higher-risk myelodysplastic syndromes
-
Steensma DP (2009) Decitabine treatment of patients with higher-risk myelodysplastic syndromes. Leuk Res 33 (Suppl 2):S12-S17.
-
(2009)
Leuk Res
, vol.33
, pp. S12-S17
-
-
Steensma, D.P.1
-
34
-
-
84868282332
-
Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems
-
Tang H, Lee M, Sharpe O, Salamone L, Noonan EJ, Hoang CD, Levine S, Robinson WH, and Shrager JB (2012) Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems. FASEB J 26:4710-4721.
-
(2012)
FASEB J
, vol.26
, pp. 4710-4721
-
-
Tang, H.1
Lee, M.2
Sharpe, O.3
Salamone, L.4
Noonan, E.J.5
Hoang, C.D.6
Levine, S.7
Robinson, W.H.8
Shrager, J.B.9
-
35
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
Tavazoie SF, Alarcón C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL, and Massagué J (2008) Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451:147-152.
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
Alarcón, C.2
Oskarsson, T.3
Padua, D.4
Wang, Q.5
Bos, P.D.6
Gerald, W.L.7
Massagué, J.8
-
36
-
-
84866550833
-
Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer
-
Wee EJ, Peters K, Nair SS, Hulf T, Stein S, Wagner S, Bailey P, Lee SY, Qu WJ, and Brewster B et al. (2012) Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer. Oncogene 31: 4182-4195.
-
(2012)
Oncogene
, vol.31
, pp. 4182-4195
-
-
Wee, E.J.1
Peters, K.2
Nair, S.S.3
Hulf, T.4
Stein, S.5
Wagner, S.6
Bailey, P.7
Lee, S.Y.8
Qu, W.J.9
Brewster, B.10
-
37
-
-
79951938163
-
DNA methylation of tumor suppressor miRNA genes: A lesson from the miR-34 family
-
Wong KY, Yu L, and Chim CS (2011) DNA methylation of tumor suppressor miRNA genes: a lesson from the miR-34 family. Epigenomics 3:83-92.
-
(2011)
Epigenomics
, vol.3
, pp. 83-92
-
-
Wong, K.Y.1
Yu, L.2
Chim, C.S.3
|