Interaction of interferon gamma-induced reactive oxygen species with ceftazidime leads to synergistic killing of intracellular burkholderia pseudomallei

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 10, 2014, Pages 5954-5963

  Mosovsky, Kara ^a   Silva, Ediane ^a   Troyer, Ryan ^a   Propst Graham, Katie ^a   Dow, Steven ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUTHIONINE SULFOXIMINE; CEFTAZIDIME; REACTIVE OXYGEN METABOLITE; RECOMBINANT GAMMA INTERFERON; GAMMA INTERFERON;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL LOAD; BACTERICIDAL ACTIVITY; BURKHOLDERIA PSEUDOMALLEI; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; EXPERIMENTAL INFECTION; FEMALE; FIBROBLAST CULTURE; FLUORESCENCE MICROSCOPY; GIANT CELL; IMMUNOSTIMULATION; IMMUNOTHERAPY; INTRACELLULAR KILLING; MACROPHAGE; MELIOIDOSIS; MOUSE; NONHUMAN; PHAGOCYTOSIS; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL CULTURE; CELL LINE; CHEMISTRY; DRUG EFFECTS; FLOW CYTOMETRY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM;

ANIMALS; BURKHOLDERIA PSEUDOMALLEI; CEFTAZIDIME; CELL LINE; CELLS, CULTURED; FEMALE; FLOW CYTOMETRY; INTERFERON-GAMMA; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED ICR; MICROSCOPY, FLUORESCENCE; REACTIVE OXYGEN SPECIES;

EID: 84907909027     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02781-14     Document Type: Article

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