Induction of iNOS expression and antimicrobial activity by interferon (IFN)-β is distinct from IFN-γ in Burkholderia pseudomallei-infected mouse macrophages

Clinical and Experimental Immunology

Volumn 136, Issue 2, 2004, Pages 277-283

  Utaisincharoen, P ^a   Anuntagool, N ^b   Arjcharoen, S ^a   Limposuwan, K ^a   Chaisuriya, P ^b   Sirisinha, S ^a,b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b Laboratory of Immunology   (Thailand)

Author keywords

Antimicrobial activity; Burkholderia pseudomallei; IFN ; IFN ; iNOS IRF 1

Indexed keywords

ANTIINFECTIVE AGENT; BETA INTERFERON; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 1;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; BACTERICIDAL ACTIVITY; BURKHOLDERIA PSEUDOMALLEI; CELL ACTIVATION; CELL STIMULATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INDUCTION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BURKHOLDERIA PSEUDOMALLEI; CELL COUNT; CELL LINE; DNA-BINDING PROTEINS; IMMUNOBLOTTING; INTERFERON REGULATORY FACTOR-1; INTERFERON TYPE II; INTERFERON-BETA; MACROPHAGE ACTIVATION; MACROPHAGES; MELIOIDOSIS; MICE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHOPROTEINS;

EID: 2142816722     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02445.x     Document Type: Article

References (31)

1. Dharakul T, Songsivilai S. The many facets of melioidosis. Trends Microbiol 1999; 7:138-46.
2. Leelarasame S, Bovonkitti S. Melioidosis: review and update. Rev Infect Dis 1989; 11:413-25.
3. Yabuuchi E, Arakawa M. Burkholderia pseudomallei and melioidosis: be aware in temperate area. Microbiol Immunol 1993; 37:823-36.
4. Jone A, Beveridge TJ. Woods DE. Intracellular survival of Burkholderia pseudomallei. Infect Immun 1996; 64:782-90.
5. Harley VS, Dance DAB, Drasar BJ, Tovey G. Effects of Burkhoderia pseudomallei and other Burkhoderia species on eukaryotic cells in tissue culture. Microbios 1998; 96:71-93.
6. Kespichayawattana W, Rattanachetkul S, Wanun T, Utaisincharoen P, Sirisinha S. Burkholderia pseudomallei induces cell fusion and actin-associate membrane protusion: a possible mechanism for cell-to-cell spreading. Infect Immun; 200 (68):5377-84.
7. Utaisincharoen P, Tangthawornchaikul N, Kespichayawattana W, Chaisuriya P, Sirisinha S. Burkholderia pseudomallei interferes with inducible nitric oxide synthase (iNOS) production: a possible mechanism of evading macrophage killing. Microbiol Immunol 2001; 45:307-13.
8. Bogdan C, Rollinghoff M, Difenbach A. Reactive oxygen and reactive nitrogen intermediate in innate and specific immunity. Curr Opin Immunol 2000; 12:64-76.
9. Bogdan C, Rollinghoff M, Diefenbach A. The role of nitric oxide in innate immunity. Immunol Rev 2000; 173:17-26.
10. Santanirad P, Harley VS, Dance DAB, Drasar BS, Bancroft GJ. Obligatory role in gamma interferon for host survival in murine model of infection with Burkholderia pseudomallei. Infect Immun 1999; 67:3593-600.
11. Utaisincharoen P, Anuntagool N, Limposuwan K, Chaisuriya P, Sirisinha S. Involvement of IFN-β in enhancing inducible nitric oxide synthase (iNOS) production and antimicrobial activity of B. pseudomallei infected macrophages. Infect Immun 2003; 71:3053-7.
12. Kamijo R, Harda H, Matsuyama T et al. Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science 1994; 263:1612-5.
13. Martin E, Nathan C, Xie QW. Role of interferon regulatory factor in induction of nitric oxide synthase. J Exp Med 1994; 180:977-84.
14. Jacob AT, Ignarro LJ. LPS-induced expression of IFN-β mediated the timing of iNOS induction in RAW 264.7 macrophages. J Biol Chem 2001; 51:47950-7.
15. Taniguchi T, Ogasawara K, Takaoka A, Tanaka N. IRF family of transcription factors as regulators of host defense. Ann Rev Immunol 2001; 19:623-55.
16. Miyamoto M, Fujita T, Kimura Y et al. Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory element. Cell 1988; 54:903-13.
17. - clinical isolate. Clin Diagn Lab Immunol 1998; 5:225-9.
18. Kawahara K, Dejsirilert S, Danbara H, Ezaki T. Extraction and characterization of lipopolysaccharide from Pseudomonas pseudomallei. FEMS Microbiol Lett 1992; 96:129-34.
19. Wuthiekanun V, Smith MD, Dance DAB, Walsh AL, Pitt TL, White NJ. Biochemical characteristics of clinical and environmental isolates of Burkholderia pseudomallei. J Med Microbiol 1996; 45:408-12.
20. MacMicking J, Xie Q, Nathan C. Nitric oxide and macrophages function. Ann Rev Immunol 1997; 15:323-50.
21. Diefenbach A, Schindler H, Donhauser N et al. Type I interferon (IFN alpha/beta) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite. Immunity 1998; 8:77-87.
22. MacMicking J, North R, LaCourse R, Mudgett J, Shah S, Nathan C. Identification of NOS2 as a protective locus against tuberculosis. Proc Natl Acad Sci USA 1997; 94:5243-8.
23. MacMicking J, Nathan C, Horn G et al. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 1995; 81:641-50.
24. Chan E, Morris K, Belisle J et al. Induction of inducible nitric oxide synthase-NO by lipoarabinomannan of Mycrobacterium turberculosis is mediated by MEK1-ERK, MKK7-JNK, and NF-κB signaling pathway. Infect Immun 2001; 69:2001-10.
25. Lorsbach R, Russell S. A specific sequence of stimulation is required to induce synthesis of the antimicrobial molecule nitric oxide by mouse macrophages. Infect Immun 1992; 60:2133-5.
26. Zhang X, Alley E, Russell S, Morrison D. Necessity and sufficiency of beta interferon for nitric oxide production in mouse peritoneal macrophages. Infect Immun 1994; 62:33-40.
27. Mattner J, Schindler H, Diefenbach A, Rollinghoff M, Gresser I, Bogdan C. Regulation of type 2 nitric oxide synthase by type I interferon in macrophages infected with Leishmania major. Eur J Immunol 2000; 30:2257-67.
28. Utaisincharoen P, Tangthawornchaikul N, Kespichayawattana W, Anuntagool N, Chaisuriya P, Sirisinha S. Kinetic studies of the production of nitric oxide and tumor necrosis factor-alpha in macrophages stimulated with Burkholderia pseudomallei endotoxin. Clin Exp Immunol 2000; 122:324-9.
29. Miyagi K, Kawakami K, Saito A. Role of reactive nitrogen and oxygen intermediates in gamma interferon stimulated murine macrophage bactericidal activity against Burkholderia pseudomallei. Infect Immun 1997; 67:4108-13.
30. Shtrichman R, Samuel C. The role of gamma interferon in antimicrobial immunity. Curr Opin Microbiol 2001; 4:251-9.
31. Decker T, Stockinger S, Karaghiosoff M, Muller M, Kovarik P. IFNs and STATs in innate immunity to microorganisms. J Clin Invest 2002; 109:1271-7.