A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explants

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Barnable, Patrick ^a   Calenda, Giulia ^a   Ouattara, Louise ^a   Gettie, Agegnehu ^b   Blanchard, James ^c   Jean Pierre, Ninochka ^a   Kizima, Larisa ^a   Rodríguez, Aixa ^a   Abraham, Ciby ^a   Menon, Radhika ^a   Seidor, Samantha ^a   Cooney, Michael L ^a   Roberts, Kevin D ^a   Sperling, Rhoda ^d   Piatak, Michael ^e   Lifson, Jeffrey D ^e   Fernandez Romero, Jose A ^a   Zydowsky, Thomas M ^a   Robbiani, Melissa ^a   Teleshova, Natalia ^a  

^a POPULATION COUNCIL   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CARRAGEENAN PLUS MIV 150; CARRAGEENAN PLUS MIV 150 PLUS ZINC ACETATE; MIV 150; PLACEBO; UNCLASSIFIED DRUG; ZINC ACETATE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CARRAGEENAN; GEL; PYRIDINE DERIVATIVE; UREA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; EX VIVO STUDY; EXPLANT; FEMALE; GEL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IN VIVO STUDY; NONHUMAN; PROTECTION; REPEATED DRUG DOSE; RHESUS MONKEY; SEMINAL PLASMA; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; UTERINE CERVIX MUCOSA; VAGINA MUCOSA; VIRUS TRANSMISSION; ADMINISTRATION AND DOSAGE; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DRUG EFFECTS; GENETICS; INTRAVAGINAL DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; MUCOSA; SIMIAN IMMUNODEFICIENCY VIRUS; TISSUE CULTURE TECHNIQUE; VAGINA; VIROLOGY; VIRUS REPLICATION;

MACACA; SIMIAN-HUMAN IMMUNODEFICIENCY VIRUS;

ADMINISTRATION, INTRAVAGINAL; ANIMALS; ANTI-HIV AGENTS; CARRAGEENAN; CHEMISTRY, PHARMACEUTICAL; FEMALE; GELS; HUMANS; MACACA MULATTA; MUCOUS MEMBRANE; PYRIDINES; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; TISSUE CULTURE TECHNIQUES; UREA; VAGINA; VIRUS REPLICATION; ZINC ACETATE;

EID: 84907908413     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108109     Document Type: Article

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