-
1
-
-
79960013099
-
Bioelectronic delivery of electrons to cytochrome P450 enzymes
-
Krishnan, S.; Schenkman, J. B.; Rusling, J. F. Bioelectronic delivery of electrons to cytochrome P450 enzymes J. Phys. Chem. B 2011, 115, 8371-8380
-
(2011)
J. Phys. Chem. B
, vol.115
, pp. 8371-8380
-
-
Krishnan, S.1
Schenkman, J.B.2
Rusling, J.F.3
-
2
-
-
0035425177
-
Engineering and design in the bioelectrochemistry of metalloproteins
-
Gilardi, G.; Fantuzzi, A.; Sadeghi, S. J. Engineering and design in the bioelectrochemistry of metalloproteins Curr. Opin. Struc. Biol. 2001, 11, 491-499
-
(2001)
Curr. Opin. Struc. Biol.
, vol.11
, pp. 491-499
-
-
Gilardi, G.1
Fantuzzi, A.2
Sadeghi, S.J.3
-
3
-
-
0033569516
-
Pharmacogenomics: Translating functional genomics into rational therapeutics
-
Evans, W. E.; Relling, M. V. Pharmacogenomics: Translating functional genomics into rational therapeutics Science 1999, 286, 487-491
-
(1999)
Science
, vol.286
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
4
-
-
33751222848
-
Electrical contacting of redox proteins by nanotechnological means
-
Willner, B.; Katz, E.; Willner, I. Electrical contacting of redox proteins by nanotechnological means Curr. Opin. Biotechnol. 2006, 17, 589-596
-
(2006)
Curr. Opin. Biotechnol.
, vol.17
, pp. 589-596
-
-
Willner, B.1
Katz, E.2
Willner, I.3
-
5
-
-
67650517516
-
Electrochemically driven drug metabolism by membranes containing human cytochrome P450
-
Mie, Y.; Suzuki, M.; Komatsu, Y. Electrochemically driven drug metabolism by membranes containing human cytochrome P450 J. Am. Chem. Soc. 2009, 131, 6646-6647
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 6646-6647
-
-
Mie, Y.1
Suzuki, M.2
Komatsu, Y.3
-
6
-
-
18044384858
-
Cytochrome P450 biosensors - A review
-
Bistolas, N.; Wollenbergera, U.; Jung, C.; Scheller, F. W. Cytochrome P450 biosensors - A review Biosens. Bioelectron 2005, 20, 2408-2423
-
(2005)
Biosens. Bioelectron
, vol.20
, pp. 2408-2423
-
-
Bistolas, N.1
Wollenbergera, U.2
Jung, C.3
Scheller, F.W.4
-
7
-
-
1542706401
-
Direct electrochemistry of cytochrome P450cam
-
Kazlauskaite, J.; Westlake, A. C. G.; Wong, L. L.; Hill, H. A. O. Direct electrochemistry of cytochrome P450cam Chem. Commun. 1996, 2189-2190
-
(1996)
Chem. Commun.
, pp. 2189-2190
-
-
Kazlauskaite, J.1
Westlake, A.C.G.2
Wong, L.L.3
Hill, H.A.O.4
-
8
-
-
79551694936
-
Efficient bioelectronic actuation of the natural catalytic pathway of human metabolic cytochrome P450s
-
Krishnan, S.; Wasalathanthri, D.; Zhao, L. L.; Schenkman, J. B.; Rusling, J. F. Efficient bioelectronic actuation of the natural catalytic pathway of human metabolic cytochrome P450s J. Am. Chem. Soc. 2011, 133, 1459-1465
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 1459-1465
-
-
Krishnan, S.1
Wasalathanthri, D.2
Zhao, L.L.3
Schenkman, J.B.4
Rusling, J.F.5
-
9
-
-
56449113774
-
Protein and electrode engineering for the covalent immobilization of P450 BMP on gold
-
Ferrero, V. E. V.; Andolfi, L.; Nardo, D. G.; Sadeghi, S. J.; Fantuzzi, A.; Cannistraro, S.; Gilardi, G. Protein and electrode engineering for the covalent immobilization of P450 BMP on gold Anal. Chem. 2008, 80, 8438-8446
-
(2008)
Anal. Chem.
, vol.80
, pp. 8438-8446
-
-
Ferrero, V.E.V.1
Andolfi, L.2
Nardo, D.G.3
Sadeghi, S.J.4
Fantuzzi, A.5
Cannistraro, S.6
Gilardi, G.7
-
10
-
-
0142025155
-
BM3 measured by direct methods
-
BM3 measured by direct methods Eur. J. Biochem. 2003, 270, 4082-4088
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 4082-4088
-
-
Fleming, B.D.1
Tian, Y.2
Bell, S.G.3
Wong, L.4
Urlacher, V.5
Hill, H.A.O.6
-
11
-
-
0038016455
-
Epoxidation of styrene by human cyt P450 1A2 by thin film electrolysis and peroxide activation compared to solution reactions
-
Estavillo, C.; Lu, Z.; Jansson, I.; Schenkman, J. B.; Rusling, J. F. Epoxidation of styrene by human cyt P450 1A2 by thin film electrolysis and peroxide activation compared to solution reactions Biophys. Chem. 2003, 104, 291-296
-
(2003)
Biophys. Chem.
, vol.104
, pp. 291-296
-
-
Estavillo, C.1
Lu, Z.2
Jansson, I.3
Schenkman, J.B.4
Rusling, J.F.5
-
12
-
-
0038054179
-
An amperometric biosensor with human CYP3A4 as a novel drug screening tool
-
Joseph, S.; Rusling, J. F.; Lvov, Y. M.; Friedberg, T.; Fuhr, U. An amperometric biosensor with human CYP3A4 as a novel drug screening tool Biochem. Pharmacol. 2003, 65, 1817-1826
-
(2003)
Biochem. Pharmacol.
, vol.65
, pp. 1817-1826
-
-
Joseph, S.1
Rusling, J.F.2
Lvov, Y.M.3
Friedberg, T.4
Fuhr, U.5
-
13
-
-
84884999874
-
Human cytochrome P450 3A4 and a carbon nanofiber modified film electrode as a platform for the simple evaluation of drug metabolism and inhibition reactions
-
Xue, Q.; Kato, D.; Kamata, T.; Guo, Q. H.; You, T. Y.; Niwa, O. Human cytochrome P450 3A4 and a carbon nanofiber modified film electrode as a platform for the simple evaluation of drug metabolism and inhibition reactions Analyst 2013, 138, 6463-6468
-
(2013)
Analyst
, vol.138
, pp. 6463-6468
-
-
Xue, Q.1
Kato, D.2
Kamata, T.3
Guo, Q.H.4
You, T.Y.5
Niwa, O.6
-
14
-
-
54549096953
-
Electrochemistry of cytochrome P450 2B6 on electrodes modified with zirconium dioxide nanoparticles and platin components
-
Peng, L.; Yang, X. D.; Zhang, Q. Q.; Liu, S. Q. Electrochemistry of cytochrome P450 2B6 on electrodes modified with zirconium dioxide nanoparticles and platin components Electroanal. 2008, 20, 803-807
-
(2008)
Electroanal.
, vol.20
, pp. 803-807
-
-
Peng, L.1
Yang, X.D.2
Zhang, Q.Q.3
Liu, S.Q.4
-
15
-
-
40649086027
-
Electrochemistry of cytochrome P450 enzyme on nanoparticle-containing membrane-coated electrode and its applications for drug sensing
-
Liu, S. Q.; Peng, L.; Yang, X. D.; Wu, Y. F.; He, L. Electrochemistry of cytochrome P450 enzyme on nanoparticle-containing membrane-coated electrode and its applications for drug sensing Anal. Biochem. 2008, 375, 209-216
-
(2008)
Anal. Biochem.
, vol.375
, pp. 209-216
-
-
Liu, S.Q.1
Peng, L.2
Yang, X.D.3
Wu, Y.F.4
He, L.5
-
16
-
-
84863918889
-
Electrochemically driven drug metabolism via cytochrome P450 2C9 isozyme microsomes with cytochrome P450 reductase and indium tin oxide nanoparticle composites
-
Xu, X.; Wei, W.; Huang, M. H.; Yao, L.; Liu, S. Q. Electrochemically driven drug metabolism via cytochrome P450 2C9 isozyme microsomes with cytochrome P450 reductase and indium tin oxide nanoparticle composites Chem. Commun. 2012, 48, 7802-7804
-
(2012)
Chem. Commun.
, vol.48
, pp. 7802-7804
-
-
Xu, X.1
Wei, W.2
Huang, M.H.3
Yao, L.4
Liu, S.Q.5
-
17
-
-
84870013862
-
Electrochemically-driven and dynamic enhancement of drug metabolism via cytochrome P450 microsomes on colloidal gold/graphene nanocomposites
-
Huang, M. H.; Xu, X.; Yang, H.; Liu, S. Q. Electrochemically-driven and dynamic enhancement of drug metabolism via cytochrome P450 microsomes on colloidal gold/graphene nanocomposites RSC Adv. 2012, 2, 12844-12850
-
(2012)
RSC Adv.
, vol.2
, pp. 12844-12850
-
-
Huang, M.H.1
Xu, X.2
Yang, H.3
Liu, S.Q.4
-
18
-
-
84876540871
-
Reduction of graphene oxide with l -lysine to prepare reduced graphene oxide stabilized with polysaccharide polyelectrolyte
-
Ma, J. K.; Wang, X. R.; Liu, Y.; Wu, T.; Liu, Y.; Guo, Y. Q.; Li, R. Q.; Sun, X. Y.; Wu, F.; Li, C. B.; Gao, J. P. Reduction of graphene oxide with l -lysine to prepare reduced graphene oxide stabilized with polysaccharide polyelectrolyte J. Mater. Chem. A 2013, 1, 2192-2201
-
(2013)
J. Mater. Chem. A
, vol.1
, pp. 2192-2201
-
-
Ma, J.K.1
Wang, X.R.2
Liu, Y.3
Wu, T.4
Liu, Y.5
Guo, Y.Q.6
Li, R.Q.7
Sun, X.Y.8
Wu, F.9
Li, C.B.10
Gao, J.P.11
-
19
-
-
84876549371
-
In situ synthesis of the reduced graphene oxide-polyethyleneimine composite and its gas barrier properties
-
Liu, H. Y.; Kuila, T.; Kim, N. H.; Ku, B. C.; Lee, J. H. In situ synthesis of the reduced graphene oxide-polyethyleneimine composite and its gas barrier properties J. Mater. Chem. A 2013, 1, 3739-3746
-
(2013)
J. Mater. Chem. A
, vol.1
, pp. 3739-3746
-
-
Liu, H.Y.1
Kuila, T.2
Kim, N.H.3
Ku, B.C.4
Lee, J.H.5
-
20
-
-
84886085585
-
Surface modification and PEGylation of branched polyethyleneimine for improved biocompatibility
-
Wen, S. H.; Zheng, F. Y.; Shen, M. W.; Shi, X. Y. Surface modification and PEGylation of branched polyethyleneimine for improved biocompatibility J. Appl. Polym. Sci. 2013, 128, 3807-3813
-
(2013)
J. Appl. Polym. Sci.
, vol.128
, pp. 3807-3813
-
-
Wen, S.H.1
Zheng, F.Y.2
Shen, M.W.3
Shi, X.Y.4
-
21
-
-
84873689153
-
Flow injection chemiluminescence immunoassay of microcystin-LR by using PEI-modified magnetic beads as capturer and HRP-functionalized silica nanoparticles as signal amplifier
-
Lu, J. S.; Wei, W.; Yin, L. H.; Pu, Y. P.; Liu, S. Q. Flow injection chemiluminescence immunoassay of microcystin-LR by using PEI-modified magnetic beads as capturer and HRP-functionalized silica nanoparticles as signal amplifier Analyst 2013, 138, 1483-1489
-
(2013)
Analyst
, vol.138
, pp. 1483-1489
-
-
Lu, J.S.1
Wei, W.2
Yin, L.H.3
Pu, Y.P.4
Liu, S.Q.5
-
22
-
-
0036046179
-
Human variability in polymorphic CYP2D6 metabolism: Is the kinetic default uncertainty factor adequate?
-
Dorne, J. L. C. M.; Walton, K.; Slob, W.; Renwick, A. G. Human variability in polymorphic CYP2D6 metabolism: Is the kinetic default uncertainty factor adequate? Food Chem. Toxicol. 2002, 40, 1633-1656
-
(2002)
Food Chem. Toxicol.
, vol.40
, pp. 1633-1656
-
-
Dorne, J.L.C.M.1
Walton, K.2
Slob, W.3
Renwick, A.G.4
-
23
-
-
0025805934
-
Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism
-
Gaedigk, A.; Blum, M.; Gaedigk, R.; Eichelbaum, M.; Meyer, U. A. Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism Am. J. Hum. Genet. 1991, 48, 943-950
-
(1991)
Am. J. Hum. Genet.
, vol.48
, pp. 943-950
-
-
Gaedigk, A.1
Blum, M.2
Gaedigk, R.3
Eichelbaum, M.4
Meyer, U.A.5
-
24
-
-
0029916361
-
Investigation of xenobiotic metabolism by CYP2D6 and CYP2C19: Importance of enantioselective analytical methods
-
Marzo, A.; Balant, L. P. Investigation of xenobiotic metabolism by CYP2D6 and CYP2C19: Importance of enantioselective analytical methods J. Chromatogr. B 1996, 678, 73-92
-
(1996)
J. Chromatogr. B
, vol.678
, pp. 73-92
-
-
Marzo, A.1
Balant, L.P.2
-
25
-
-
84860250546
-
3,4,9,10-Perylenetetracarboxylic dianhydride functionalized graphene sheet as labels for ultrasensitive electrochemiluminescent detection of thrombin
-
Gan, X. X.; Yuan, R.; Chai, Y. Q.; Yuan, Y. L.; Cao, Y. L.; Liao, Y. H.; Liu, H. J. 3,4,9,10-Perylenetetracarboxylic dianhydride functionalized graphene sheet as labels for ultrasensitive electrochemiluminescent detection of thrombin Anal. Chim. Acta 2012, 726, 67-72
-
(2012)
Anal. Chim. Acta
, vol.726
, pp. 67-72
-
-
Gan, X.X.1
Yuan, R.2
Chai, Y.Q.3
Yuan, Y.L.4
Cao, Y.L.5
Liao, Y.H.6
Liu, H.J.7
-
26
-
-
49249148639
-
General expression of the linear potential sweep voltammogram in the case of diffusionless electrochemical systems
-
Laviron, E. General expression of the linear potential sweep voltammogram in the case of diffusionless electrochemical systems J. Electroanal. Chem. 1979, 101, 19-28
-
(1979)
J. Electroanal. Chem.
, vol.101
, pp. 19-28
-
-
Laviron, E.1
-
27
-
-
84900674271
-
Electrochemical detection of human cytochrome P450 2A6 inhibition: A step toward reducing dependence on smoking
-
Castrignano, S.; Ortolani, A.; Sadeghi, S. J.; Nardo, G. D.; Allegr, P.; Gilardi, G. Electrochemical detection of human cytochrome P450 2A6 inhibition: A step toward reducing dependence on smoking Anal. Chem. 2014, 86, 2760-2766
-
(2014)
Anal. Chem.
, vol.86
, pp. 2760-2766
-
-
Castrignano, S.1
Ortolani, A.2
Sadeghi, S.J.3
Nardo, G.D.4
Allegr, P.5
Gilardi, G.6
-
28
-
-
37349032819
-
Biochemical applications of ultrathin films of enzymes, polyions and DNA
-
Rusling, J. F.; Hvastkovs, E. G.; Hull, D. O.; Schenkman, J. B. Biochemical applications of ultrathin films of enzymes, polyions and DNA Chem. Commun. 2008, 141-154
-
(2008)
Chem. Commun.
, pp. 141-154
-
-
Rusling, J.F.1
Hvastkovs, E.G.2
Hull, D.O.3
Schenkman, J.B.4
-
29
-
-
0034946742
-
Identification of cytochrome P-450 isoforms responsible for cis -tramadol metabolism in human liver microsomes
-
Subraahmanyam, V.; Renwick, A. B.; Walters, D. G.; Young, P. J.; Price, R. J.; Tonelli, A. P.; Lake, B. G. Identification of cytochrome P-450 isoforms responsible for cis -tramadol metabolism in human liver microsomes Drug Metab. Dispos. 2001, 29, 1146-1155
-
(2001)
Drug Metab. Dispos.
, vol.29
, pp. 1146-1155
-
-
Subraahmanyam, V.1
Renwick, A.B.2
Walters, D.G.3
Young, P.J.4
Price, R.J.5
Tonelli, A.P.6
Lake, B.G.7
-
30
-
-
0019035135
-
Rotating ring-disk enzyme electrode for biocatalysis kinetic studies and characterization of the immobilized enzyme layer
-
Kamin, R. A.; Wilson, G. S. Rotating ring-disk enzyme electrode for biocatalysis kinetic studies and characterization of the immobilized enzyme layer Anal. Chem. 1980, 52, 1198-1205
-
(1980)
Anal. Chem.
, vol.52
, pp. 1198-1205
-
-
Kamin, R.A.1
Wilson, G.S.2
-
31
-
-
0025671780
-
Glucose fast-response amperometric sensor based on glucose oxidase immobilized in an electropolymerized poly(o -phenylenediamine) film
-
Malitesta, C.; Palmisano, F.; Torsi, L.; Zambonin, P. G. Glucose fast-response amperometric sensor based on glucose oxidase immobilized in an electropolymerized poly(o -phenylenediamine) film Anal. Chem. 1990, 62, 2735-2740
-
(1990)
Anal. Chem.
, vol.62
, pp. 2735-2740
-
-
Malitesta, C.1
Palmisano, F.2
Torsi, L.3
Zambonin, P.G.4
-
32
-
-
79956086806
-
A new standardized electrochemical array for drug metabolic profiling with human cytochromes P450
-
Fantuzzi, A.; Mak, L. H.; Capria, E.; Dodhia, V.; Panicco, P.; Collins, S.; Gilardi, G. A new standardized electrochemical array for drug metabolic profiling with human cytochromes P450 Anal. Chem. 2011, 83, 3831-3839
-
(2011)
Anal. Chem.
, vol.83
, pp. 3831-3839
-
-
Fantuzzi, A.1
Mak, L.H.2
Capria, E.3
Dodhia, V.4
Panicco, P.5
Collins, S.6
Gilardi, G.7
-
33
-
-
77956032548
-
Nitrogen-doped ordered mesoporous graphitic arrays with high electrocatalytic activity for oxygen reduction
-
Liu, R. L.; Wu, D. Q.; Feng, X. L.; Müllen, K. Nitrogen-doped ordered mesoporous graphitic arrays with high electrocatalytic activity for oxygen reduction Angew. Chem., Int. Ed. 2010, 122, 2619-2623
-
(2010)
Angew. Chem., Int. Ed.
, vol.122
, pp. 2619-2623
-
-
Liu, R.L.1
Wu, D.Q.2
Feng, X.L.3
Müllen, K.4
-
34
-
-
42449134525
-
Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice
-
Raffa, R. B.; S, D. J., Jr. Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice J. Pharmacol. Exp. Ther. 2008, 325, 500-506
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.325
, pp. 500-506
-
-
Raffa Jr. R.B.S, D.J.1
-
35
-
-
77953554845
-
Control of human cytochrome P450 2E1 electrocatalytic response as a result of unique orientation on gold electrodes
-
Mak, L. H.; Sadeghi, S. J.; Fantuzzi, A.; Gilardi, G. Control of human cytochrome P450 2E1 electrocatalytic response as a result of unique orientation on gold electrodes Anal. Chem. 2010, 82, 5357-5362
-
(2010)
Anal. Chem.
, vol.82
, pp. 5357-5362
-
-
Mak, L.H.1
Sadeghi, S.J.2
Fantuzzi, A.3
Gilardi, G.4
-
36
-
-
0037369622
-
Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: Comparison with fluoxetine and quinidine
-
Bertelsen, K. M.; Venkatakrishnan, K.; Moltke, L. L. V.; Obach, R. S.; Greenblatt, D. J. Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: Comparison with fluoxetine and quinidine Drug Metab. Dispos. 2003, 31, 289-293
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 289-293
-
-
Bertelsen, K.M.1
Venkatakrishnan, K.2
Moltke, L.L.V.3
Obach, R.S.4
Greenblatt, D.J.5
-
37
-
-
0032815783
-
Comparison of CYP2D6 content and metoprolol oxidation between microsomes isolated from human livers and small intestines
-
Madani, S.; Paine, M. F.; Lewis, L.; Thummel, K. E.; Shen, D. D. Comparison of CYP2D6 content and metoprolol oxidation between microsomes isolated from human livers and small intestines Pharm. Res. 1999, 16, 1199-1205
-
(1999)
Pharm. Res.
, vol.16
, pp. 1199-1205
-
-
Madani, S.1
Paine, M.F.2
Lewis, L.3
Thummel, K.E.4
Shen, D.D.5
-
38
-
-
34047209775
-
Mixture models and subpopulation classification: A pharmacokinetic simulation study and application to metoprolol CYP2D6 phenotype
-
Kaila, N.; Straka, R. J.; Brundage, R. C. Mixture models and subpopulation classification: A pharmacokinetic simulation study and application to metoprolol CYP2D6 phenotype J. Pharmacokinet. Phar. 2007, 34, 141-156
-
(2007)
J. Pharmacokinet. Phar.
, vol.34
, pp. 141-156
-
-
Kaila, N.1
Straka, R.J.2
Brundage, R.C.3
-
39
-
-
33645129348
-
Catalytic roles of CYP2D6.10 and CYP2D6.36 enzymes in mexiletine metabolism: In vitro functional analysis of recombinant proteins expressed in Saccharomyces cerevisiae
-
Hanioka, N.; Okumura, Y.; Saito, Y.; Hichiya, H.; Soyama, A.; Saito, K.; Ueno, K.; Sawada, J.; Sawada, J.; Narimatsu, S. Catalytic roles of CYP2D6.10 and CYP2D6.36 enzymes in mexiletine metabolism: In vitro functional analysis of recombinant proteins expressed in Saccharomyces cerevisiae Biochem. Pharmacol. 2006, 71, 1386-1395
-
(2006)
Biochem. Pharmacol.
, vol.71
, pp. 1386-1395
-
-
Hanioka, N.1
Okumura, Y.2
Saito, Y.3
Hichiya, H.4
Soyama, A.5
Saito, K.6
Ueno, K.7
Sawada, J.8
Sawada, J.9
Narimatsu, S.10
-
40
-
-
0027390996
-
Stereoselective hydroxylation of mexiletine in human liver microsomes: Implication of P450IID6-A preliminary report
-
Vandamme, N.; Broly, F.; Libersa, C.; Courseau, C.; Lhermitte, M. Stereoselective hydroxylation of mexiletine in human liver microsomes: Implication of P450IID6-A preliminary report J. Cardiovasc. Pharm. 1993, 21, 77-83
-
(1993)
J. Cardiovasc. Pharm.
, vol.21
, pp. 77-83
-
-
Vandamme, N.1
Broly, F.2
Libersa, C.3
Courseau, C.4
Lhermitte, M.5
-
41
-
-
33746042623
-
In silico prediction of drug binding to CYP2D6: Idetification of a new metobolite of metoclopramide
-
Yu, J. L.; Paine, M. J. I.; Maréchal, J. D.; Kemp, C. A.; Ward, C. J.; Brown, S.; Sutcliffe, M. J.; Roberts, G. C. K.; Rankin, E. M.; Wolf, C. R. In silico prediction of drug binding to CYP2D6: Idetification of a new metobolite of metoclopramide Drug Metab. Dispos. 2006, 34, 1386-1392
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 1386-1392
-
-
Yu, J.L.1
Paine, M.J.I.2
Maréchal, J.D.3
Kemp, C.A.4
Ward, C.J.5
Brown, S.6
Sutcliffe, M.J.7
Roberts, G.C.K.8
Rankin, E.M.9
Wolf, C.R.10
-
42
-
-
0036177763
-
The gastroprokinetic and antiemetic drug metoclopramide is a substrate and inhibitor of cytochrome P450 2D6
-
Desta, Z.; Wu, G. M.; Morocho, A. M.; Flockhart, D. A. The gastroprokinetic and antiemetic drug metoclopramide is a substrate and inhibitor of cytochrome P450 2D6 Drug Metab. Dispos. 2002, 30, 336-343
-
(2002)
Drug Metab. Dispos.
, vol.30
, pp. 336-343
-
-
Desta, Z.1
Wu, G.M.2
Morocho, A.M.3
Flockhart, D.A.4
-
43
-
-
0032793678
-
Involvment of CYP2E1 as a low-affinity enzyme in phenacetin O-deethylation in human liver microsomes
-
Kobayashi, K.; Nakajima, M.; Oshima, K.; Shimada, N.; Yokoi, T.; Chiba, K. Involvment of CYP2E1 as a low-affinity enzyme in phenacetin O-deethylation in human liver microsomes Drug Metab. Dispos. 1999, 27, 860-865
-
(1999)
Drug Metab. Dispos.
, vol.27
, pp. 860-865
-
-
Kobayashi, K.1
Nakajima, M.2
Oshima, K.3
Shimada, N.4
Yokoi, T.5
Chiba, K.6
-
44
-
-
0035199681
-
The effect of CYP2C19 and CYP2D6 genotypes on the metabolism of clomipramine in Japanese psychiatric patients
-
Yokono, A.; Morpta, S.; Someya, T.; Hirokane, G.; Okawa, M.; Shimoda, K. The effect of CYP2C19 and CYP2D6 genotypes on the metabolism of clomipramine in Japanese psychiatric patients J. Clin. Psychopharm. 2001, 21, 549-555
-
(2001)
J. Clin. Psychopharm.
, vol.21
, pp. 549-555
-
-
Yokono, A.1
Morpta, S.2
Someya, T.3
Hirokane, G.4
Okawa, M.5
Shimoda, K.6
-
45
-
-
0026046988
-
A three-dimensional molecular template for substrates of human cytochrome P450 involved in debrisoquine 4-hydroxylation
-
Islam, S. A.; Wolf, C. R.; Lennard, M. S.; Sternberg, M. J. E. A three-dimensional molecular template for substrates of human cytochrome P450 involved in debrisoquine 4-hydroxylation Carcinogenesis 1991, 12, 2211-2219
-
(1991)
Carcinogenesis
, vol.12
, pp. 2211-2219
-
-
Islam, S.A.1
Wolf, C.R.2
Lennard, M.S.3
Sternberg, M.J.E.4
-
46
-
-
0037413558
-
Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities
-
Venhorst, J.; Laak, A. M.; Commandeur, J. N. M.; Funae, Y.; Hiroi, T.; Vermeulen, N. P. E. Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities J. Med. Chem. 2003, 46, 74-86
-
(2003)
J. Med. Chem.
, vol.46
, pp. 74-86
-
-
Venhorst, J.1
Laak, A.M.2
Commandeur, J.N.M.3
Funae, Y.4
Hiroi, T.5
Vermeulen, N.P.E.6
-
47
-
-
47649131927
-
Relationship of cytochrome P450 pharmacogenetics to the effects of yohimbine on gastrointestinal transit and catecholamines in healthy subjects
-
Bharucha, A. E.; Skaar, T.; Andrews, C. N.; Camilleri, M.; Philips, S.; Seide, B.; Burton, D.; Baxter, K.; Zinsmeister, A. R. Relationship of cytochrome P450 pharmacogenetics to the effects of yohimbine on gastrointestinal transit and catecholamines in healthy subjects Neurogastroenterol. Motil. 2008, 20, 891-899
-
(2008)
Neurogastroenterol. Motil.
, vol.20
, pp. 891-899
-
-
Bharucha, A.E.1
Skaar, T.2
Andrews, C.N.3
Camilleri, M.4
Philips, S.5
Seide, B.6
Burton, D.7
Baxter, K.8
Zinsmeister, A.R.9
|