Activation of ERK and P53 regulates copper oxide nanoparticle-induced cytotoxicity in keratinocytes and fibroblasts

International Journal of Nanomedicine

Volumn 9, Issue 1, 2014, Pages 4763-4772

  Luo, Cheng ^a   Li, Yan ^b   Yang, Liang ^a   Zheng, Yan ^b   Long, Jiangang ^a   Jia, Jinjing ^b   Xiao, Shengxiang ^b   Liu, Jiankang ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Cell cycle arrest; CuONP; Cyclic pifithrin ; MAPK; Nutlin 3

Indexed keywords

COPPER NANOPARTICLE; COPPER OXIDE NANOPARTICLE; CYCLIN A; CYCLIN B1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NUTLIN 3; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; COPPER; CUPROUS OXIDE; METAL NANOPARTICLE;

ANIMAL CELL; ARTICLE; CELL LEVEL; CELL POPULATION; CELL VIABILITY; CELL VIABILITY LOSS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; G2 PHASE CELL CYCLE CHECKPOINT; GROWTH INHIBITION; HUMAN; HUMAN CELL; KERATINOCYTE; MIGRATION INHIBITION; MOLECULAR PATHOLOGY; MOUSE; NEWBORN; NONHUMAN; RAT; SKIN FIBROBLAST; ZETA POTENTIAL; ANIMAL; CELL CYCLE CHECKPOINT; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; FIBROBLAST; METABOLISM;

ANIMALS; CELL CYCLE CHECKPOINTS; CELL LINE; CELL SURVIVAL; COPPER; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HUMANS; KERATINOCYTES; METAL NANOPARTICLES; MICE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84907880591     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S67688     Document Type: Article

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