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Volumn 50, Issue 10, 2014, Pages 918-923

Targeting the epidermal growth factor receptor for head and neck cancer chemoprevention

Author keywords

Cetuximab; Chemoprevention; Epidermal growth factor receptor; Erlotinib; Leukoplakia; Oral premalignant lesions

Indexed keywords

AFATINIB; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; PANITUMUMAB; RETINOID; VANDETANIB; ZALUTUMUMAB; ANTINEOPLASTIC AGENT;

EID: 84907875359     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2013.12.024     Document Type: Article
Times cited : (22)

References (51)
  • 2
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    • J.A. Bonner, P.M. Harari, J. Giralt, N. Azarnia, D.M. Shin, and R.B. Cohen Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck N Engl J Med 354 6 2006 567 578
    • (2006) N Engl J Med , vol.354 , Issue.6 , pp. 567-578
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3    Azarnia, N.4    Shin, D.M.5    Cohen, R.B.6
  • 4
    • 34250180582 scopus 로고    scopus 로고
    • Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy
    • J.B. Vermorken, J. Trigo, R. Hitt, P. Koralewski, E. Diaz-Rubio, and F. Rolland Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy J Clin Oncol 25 16 2007 2171 2177
    • (2007) J Clin Oncol , vol.25 , Issue.16 , pp. 2171-2177
    • Vermorken, J.B.1    Trigo, J.2    Hitt, R.3    Koralewski, P.4    Diaz-Rubio, E.5    Rolland, F.6
  • 5
    • 79953169590 scopus 로고    scopus 로고
    • Primary efficacy and safety results of SPECTRUM, a phase 3 trial in patients (pts) with recurrent and/or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) receiving chemotherapy with or without panitumumab (pmab)
    • abstr. LBA26
    • J.B. Vermorken, J. Stohlmacher, I. Davidenko, L. Licitra, E. Winquist, and K. Skladowski Primary efficacy and safety results of SPECTRUM, a phase 3 trial in patients (pts) with recurrent and/or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) receiving chemotherapy with or without panitumumab (pmab) Ann Oncol 21 8 2010 abstr. LBA26
    • (2010) Ann Oncol , vol.21 , Issue.8
    • Vermorken, J.B.1    Stohlmacher, J.2    Davidenko, I.3    Licitra, L.4    Winquist, E.5    Skladowski, K.6
  • 6
    • 79953183347 scopus 로고    scopus 로고
    • Zalutumumab plus best supportive care versus best supportive care alone in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after failure of platinum-based chemotherapy: An open-label, randomised phase 3 trial
    • J.P. Machiels, S. Subramanian, A. Ruzsa, G. Repassy, I. Lifirenko, and A. Flygare Zalutumumab plus best supportive care versus best supportive care alone in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after failure of platinum-based chemotherapy: an open-label, randomised phase 3 trial Lancet Oncol 12 4 2011 333 343
    • (2011) Lancet Oncol , vol.12 , Issue.4 , pp. 333-343
    • Machiels, J.P.1    Subramanian, S.2    Ruzsa, A.3    Repassy, G.4    Lifirenko, I.5    Flygare, A.6
  • 7
    • 28544432807 scopus 로고    scopus 로고
    • Phase II trial of gefitinib 250 mg daily in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck
    • E.E. Cohen, M.A. Kane, M.A. List, B.E. Brockstein, B. Mehrotra, and D. Huo Phase II trial of gefitinib 250 mg daily in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck Clin Cancer Res 11 23 2005 8418 8424
    • (2005) Clin Cancer Res , vol.11 , Issue.23 , pp. 8418-8424
    • Cohen, E.E.1    Kane, M.A.2    List, M.A.3    Brockstein, B.E.4    Mehrotra, B.5    Huo, D.6
  • 8
    • 0037674062 scopus 로고    scopus 로고
    • Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck
    • E.E. Cohen, F. Rosen, W.M. Stadler, W. Recant, K. Stenson, and D. Huo Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck J Clin Oncol 21 10 2003 1980 1987
    • (2003) J Clin Oncol , vol.21 , Issue.10 , pp. 1980-1987
    • Cohen, E.E.1    Rosen, F.2    Stadler, W.M.3    Recant, W.4    Stenson, K.5    Huo, D.6
  • 9
    • 64649097892 scopus 로고    scopus 로고
    • Phase III study of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck [corrected]
    • J.S. Stewart, E.E. Cohen, L. Licitra, C.M. Van Herpen, C. Khorprasert, and D. Soulieres Phase III study of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck [corrected] J Clin Oncol 27 11 2009 1864 1871
    • (2009) J Clin Oncol , vol.27 , Issue.11 , pp. 1864-1871
    • Stewart, J.S.1    Cohen, E.E.2    Licitra, L.3    Van Herpen, C.M.4    Khorprasert, C.5    Soulieres, D.6
  • 10
    • 1842772526 scopus 로고    scopus 로고
    • Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck
    • D. Soulieres, N.N. Senzer, E.E. Vokes, M. Hidalgo, S.S. Agarwala, and L.L. Siu Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck J Clin Oncol 22 1 2004 77 85
    • (2004) J Clin Oncol , vol.22 , Issue.1 , pp. 77-85
    • Soulieres, D.1    Senzer, N.N.2    Vokes, E.E.3    Hidalgo, M.4    Agarwala, S.S.5    Siu, L.L.6
  • 11
    • 78649386294 scopus 로고    scopus 로고
    • BIBW 2992 versus cetuximab in patients with metastatic or recurrent head and neck cancer (SCCHN) after failure of platinum-containing therapy with a cross-over period for progressing patients: Preliminary results of a randomized, open-label phase II study
    • abstr. 5501
    • T.Y. Seiwert, P.M. Clement, D. Cupissol, J.D. Campo, Hd Mont-Serrat, and H.C. Thurm BIBW 2992 versus cetuximab in patients with metastatic or recurrent head and neck cancer (SCCHN) after failure of platinum-containing therapy with a cross-over period for progressing patients: Preliminary results of a randomized, open-label phase II study J Clin Oncol 28 15S 2010 abstr. 5501
    • (2010) J Clin Oncol , vol.28 , Issue.15 S
    • Seiwert, T.Y.1    Clement, P.M.2    Cupissol, D.3    Campo, J.D.4    Mont-Serrat, H.5    Thurm, H.C.6
  • 13
    • 0037115674 scopus 로고    scopus 로고
    • Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
    • K.K. Ang, B.A. Berkey, X. Tu, H.Z. Zhang, R. Katz, and E.H. Hammond Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma Cancer Res 62 24 2002 7350 7356
    • (2002) Cancer Res , vol.62 , Issue.24 , pp. 7350-7356
    • Ang, K.K.1    Berkey, B.A.2    Tu, X.3    Zhang, H.Z.4    Katz, R.5    Hammond, E.H.6
  • 14
    • 0033056070 scopus 로고    scopus 로고
    • A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil
    • M.C. Etienne, X. Pivot, J.L. Formento, R.J. Bensadoun, P. Formento, and O. Dassonville A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil Br J Cancer 79 11-12 1999 1864 1869
    • (1999) Br J Cancer , vol.79 , Issue.1112 , pp. 1864-1869
    • Etienne, M.C.1    Pivot, X.2    Formento, J.L.3    Bensadoun, R.J.4    Formento, P.5    Dassonville, O.6
  • 15
    • 13244291646 scopus 로고    scopus 로고
    • Prognostic value of the epidermal growth factor receptor (EGRF) and p53 in advanced head and neck squamous cell carcinoma patients treated with induction chemotherapy
    • R. Hitt, E. Ciruelos, M.L. Amador, A. Benito, J.J. Sanchez, and C. Ballestin Prognostic value of the epidermal growth factor receptor (EGRF) and p53 in advanced head and neck squamous cell carcinoma patients treated with induction chemotherapy Eur J Cancer 41 3 2005 453 460
    • (2005) Eur J Cancer , vol.41 , Issue.3 , pp. 453-460
    • Hitt, R.1    Ciruelos, E.2    Amador, M.L.3    Benito, A.4    Sanchez, J.J.5    Ballestin, C.6
  • 16
    • 0032478998 scopus 로고    scopus 로고
    • Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
    • J. Rubin Grandis, M.F. Melhem, W.E. Gooding, R. Day, V.A. Holst, and M.M. Wagener Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival J Natl Cancer Inst 90 11 1998 824 832
    • (1998) J Natl Cancer Inst , vol.90 , Issue.11 , pp. 824-832
    • Rubin Grandis, J.1    Melhem, M.F.2    Gooding, W.E.3    Day, R.4    Holst, V.A.5    Wagener, M.M.6
  • 17
    • 0029963984 scopus 로고    scopus 로고
    • Coexpression of epidermal growth factor receptor and TGF-alpha and survival in upper aerodigestive tract cancer
    • W.J. Issing, C. Liebich, T.P. Wustrow, and A. Ullrich Coexpression of epidermal growth factor receptor and TGF-alpha and survival in upper aerodigestive tract cancer Anticancer Res 16 1 1996 283 288
    • (1996) Anticancer Res , vol.16 , Issue.1 , pp. 283-288
    • Issing, W.J.1    Liebich, C.2    Wustrow, T.P.3    Ullrich, A.4
  • 18
    • 0027183870 scopus 로고
    • Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer
    • J.R. Grandis, and D.J. Tweardy Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer Cancer Res 53 15 1993 3579 3584
    • (1993) Cancer Res , vol.53 , Issue.15 , pp. 3579-3584
    • Grandis, J.R.1    Tweardy, D.J.2
  • 19
    • 0029831041 scopus 로고    scopus 로고
    • Quantitative immunohistochemical analysis of transforming growth factor-alpha and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck
    • J. Rubin Grandis, M.F. Melhem, E.L. Barnes, and D.J. Tweardy Quantitative immunohistochemical analysis of transforming growth factor-alpha and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck Cancer 78 6 1996 1284 1292
    • (1996) Cancer , vol.78 , Issue.6 , pp. 1284-1292
    • Rubin Grandis, J.1    Melhem, M.F.2    Barnes, E.L.3    Tweardy, D.J.4
  • 20
    • 0028292482 scopus 로고
    • Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis
    • D.M. Shin, J.Y. Ro, W.K. Hong, and W.N. Hittelman Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis Cancer Res 54 12 1994 3153 3159
    • (1994) Cancer Res , vol.54 , Issue.12 , pp. 3153-3159
    • Shin, D.M.1    Ro, J.Y.2    Hong, W.K.3    Hittelman, W.N.4
  • 21
    • 0031693838 scopus 로고    scopus 로고
    • Increased expression of epidermal growth factor receptor in normal epithelium adjacent to head and neck carcinomas independent of tobacco and alcohol abuse
    • M.G. van Oijen, G. Rijksen, F.W. ten Broek, and P.J. Slootweg Increased expression of epidermal growth factor receptor in normal epithelium adjacent to head and neck carcinomas independent of tobacco and alcohol abuse Oral Dis 4 1 1998 4 8
    • (1998) Oral Dis , vol.4 , Issue.1 , pp. 4-8
    • Van Oijen, M.G.1    Rijksen, G.2    Ten Broek, F.W.3    Slootweg, P.J.4
  • 22
    • 0013650320 scopus 로고    scopus 로고
    • Asynchronous modulation of transforming growth factor alpha and epidermal growth factor receptor protein expression in progression of premalignant lesions to head and neck squamous cell carcinoma
    • J. Rubin Grandis, D.J. Tweardy, and M.F. Melhem Asynchronous modulation of transforming growth factor alpha and epidermal growth factor receptor protein expression in progression of premalignant lesions to head and neck squamous cell carcinoma Clin Cancer Res 4 1 1998 13 20
    • (1998) Clin Cancer Res , vol.4 , Issue.1 , pp. 13-20
    • Rubin Grandis, J.1    Tweardy, D.J.2    Melhem, M.F.3
  • 24
    • 0032847979 scopus 로고    scopus 로고
    • Transforming growth factor alpha (TGF-alpha) expression in dysplastic oral leukoplakia: Modulation by 13-cis retinoic acid
    • S.W. Beenken, M.T. Sellers, P. Huang, G. Peters, H. Krontiras, and P. Dixon Transforming growth factor alpha (TGF-alpha) expression in dysplastic oral leukoplakia: modulation by 13-cis retinoic acid Head Neck 21 6 1999 566 573
    • (1999) Head Neck , vol.21 , Issue.6 , pp. 566-573
    • Beenken, S.W.1    Sellers, M.T.2    Huang, P.3    Peters, G.4    Krontiras, H.5    Dixon, P.6
  • 26
    • 33748653109 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas
    • C.H. Chung, K. Ely, L. McGavran, M. Varella-Garcia, J. Parker, and N. Parker Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas J Clin Oncol 24 25 2006 4170 4176
    • (2006) J Clin Oncol , vol.24 , Issue.25 , pp. 4170-4176
    • Chung, C.H.1    Ely, K.2    McGavran, L.3    Varella-Garcia, M.4    Parker, J.5    Parker, N.6
  • 27
    • 34250155320 scopus 로고    scopus 로고
    • Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer
    • S. Temam, H. Kawaguchi, A.K. El-Naggar, J. Jelinek, H. Tang, and D.D. Liu Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer J Clin Oncol 25 16 2007 2164 2170
    • (2007) J Clin Oncol , vol.25 , Issue.16 , pp. 2164-2170
    • Temam, S.1    Kawaguchi, H.2    El-Naggar, A.K.3    Jelinek, J.4    Tang, H.5    Liu, D.D.6
  • 28
    • 0027162572 scopus 로고
    • Increased polysomies of chromosomes 7 and 17 during head and neck multistage tumorigenesis
    • N. Voravud, D.M. Shin, J.Y. Ro, J.S. Lee, W.K. Hong, and W.N. Hittelman Increased polysomies of chromosomes 7 and 17 during head and neck multistage tumorigenesis Cancer Res 53 12 1993 2874 2883
    • (1993) Cancer Res , vol.53 , Issue.12 , pp. 2874-2883
    • Voravud, N.1    Shin, D.M.2    Ro, J.Y.3    Lee, J.S.4    Hong, W.K.5    Hittelman, W.N.6
  • 29
    • 70249110475 scopus 로고    scopus 로고
    • Multiple pathways in the FGF signaling network are frequently deregulated by gene amplification in oral dysplasias
    • I.F. Tsui, C.F. Poh, C. Garnis, M.P. Rosin, L. Zhang, and W.L. Lam Multiple pathways in the FGF signaling network are frequently deregulated by gene amplification in oral dysplasias Int J Cancer 125 9 2009 2219 2228
    • (2009) Int J Cancer , vol.125 , Issue.9 , pp. 2219-2228
    • Tsui, I.F.1    Poh, C.F.2    Garnis, C.3    Rosin, M.P.4    Zhang, L.5    Lam, W.L.6
  • 30
    • 0034833599 scopus 로고    scopus 로고
    • Quantitation of epidermal growth factor receptor gene amplification by competitive polymerase chain reaction in pre-malignant and malignant oral epithelial lesions
    • H. Nagatsuka, Y. Ishiwari, H. Tsujigiwa, K. Nakano, and N. Nagai Quantitation of epidermal growth factor receptor gene amplification by competitive polymerase chain reaction in pre-malignant and malignant oral epithelial lesions Oral Oncol 37 7 2001 599 604
    • (2001) Oral Oncol , vol.37 , Issue.7 , pp. 599-604
    • Nagatsuka, H.1    Ishiwari, Y.2    Tsujigiwa, H.3    Nakano, K.4    Nagai, N.5
  • 31
    • 83455235876 scopus 로고    scopus 로고
    • Unique FISH patterns associated with cancer progression of oral dysplasia
    • C.F. Poh, Y. Zhu, E. Chen, K.W. Berean, L. Wu, and L. Zhang Unique FISH patterns associated with cancer progression of oral dysplasia J Dent Res 91 1 2012 52 57
    • (2012) J Dent Res , vol.91 , Issue.1 , pp. 52-57
    • Poh, C.F.1    Zhu, Y.2    Chen, E.3    Berean, K.W.4    Wu, L.5    Zhang, L.6
  • 32
    • 0031820926 scopus 로고    scopus 로고
    • Increased number of proliferating cells in oral epithelium from smokers and ex-smokers
    • M.G. van Oijen, M.M. Gilsing, G. Rijksen, G.J. Hordijk, and P.J. Slootweg Increased number of proliferating cells in oral epithelium from smokers and ex-smokers Oral Oncol 34 4 1998 297 303
    • (1998) Oral Oncol , vol.34 , Issue.4 , pp. 297-303
    • Van Oijen, M.G.1    Gilsing, M.M.2    Rijksen, G.3    Hordijk, G.J.4    Slootweg, P.J.5
  • 33
    • 19944432973 scopus 로고    scopus 로고
    • Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: Evidence for the role of epidermal growth factor receptor and its ligands
    • D. Moraitis, B. Du, M.S. De Lorenzo, J.O. Boyle, B.B. Weksler, and E.G. Cohen Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands Cancer Res 65 2 2005 664 670
    • (2005) Cancer Res , vol.65 , Issue.2 , pp. 664-670
    • Moraitis, D.1    Du, B.2    De Lorenzo, M.S.3    Boyle, J.O.4    Weksler, B.B.5    Cohen, E.G.6
  • 34
    • 0029929233 scopus 로고    scopus 로고
    • Cell, tissue and organ culture as in vitro models to study the biology of squamous cell carcinomas of the head and neck
    • P.G. Sacks Cell, tissue and organ culture as in vitro models to study the biology of squamous cell carcinomas of the head and neck Cancer Metastasis Rev 15 1 1996 27 51
    • (1996) Cancer Metastasis Rev , vol.15 , Issue.1 , pp. 27-51
    • Sacks, P.G.1
  • 35
    • 21344457895 scopus 로고    scopus 로고
    • Tobacco smoke stimulates the transcription of amphiregulin in human oral epithelial cells: Evidence of a cyclic AMP-responsive element binding protein-dependent mechanism
    • B. Du, N.K. Altorki, L. Kopelovich, K. Subbaramaiah, and A.J. Dannenberg Tobacco smoke stimulates the transcription of amphiregulin in human oral epithelial cells: evidence of a cyclic AMP-responsive element binding protein-dependent mechanism Cancer Res 65 13 2005 5982 5988
    • (2005) Cancer Res , vol.65 , Issue.13 , pp. 5982-5988
    • Du, B.1    Altorki, N.K.2    Kopelovich, L.3    Subbaramaiah, K.4    Dannenberg, A.J.5
  • 36
    • 34548727489 scopus 로고    scopus 로고
    • Tobacco smoke induces urokinase-type plasminogen activator and cell invasiveness: Evidence for an epidermal growth factor receptor dependent mechanism
    • B. Du, H. Leung, K.M. Khan, C.G. Miller, K. Subbaramaiah, and D.J. Falcone Tobacco smoke induces urokinase-type plasminogen activator and cell invasiveness: evidence for an epidermal growth factor receptor dependent mechanism Cancer Res 67 18 2007 8966 8972
    • (2007) Cancer Res , vol.67 , Issue.18 , pp. 8966-8972
    • Du, B.1    Leung, H.2    Khan, K.M.3    Miller, C.G.4    Subbaramaiah, K.5    Falcone, D.J.6
  • 37
    • 60549085049 scopus 로고    scopus 로고
    • Effects of tobacco smoke on gene expression and cellular pathways in a cellular model of oral leukoplakia
    • Z.H. Gumus, B. Du, A. Kacker, J.O. Boyle, J.M. Bocker, and P. Mukherjee Effects of tobacco smoke on gene expression and cellular pathways in a cellular model of oral leukoplakia Cancer Prev Res (Phila) 1 2 2008 100 111
    • (2008) Cancer Prev Res (Phila) , vol.1 , Issue.2 , pp. 100-111
    • Gumus, Z.H.1    Du, B.2    Kacker, A.3    Boyle, J.O.4    Bocker, J.M.5    Mukherjee, P.6
  • 38
    • 0025261739 scopus 로고
    • Expression of epidermal growth factor receptor, polyamine levels, ornithine decarboxylase activity, micronuclei, and transglutaminase i in a 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis model
    • D.M. Shin, I.B. Gimenez, J.S. Lee, K. Nishioka, M.J. Wargovich, and S. Thacher Expression of epidermal growth factor receptor, polyamine levels, ornithine decarboxylase activity, micronuclei, and transglutaminase I in a 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis model Cancer Res 50 8 1990 2505 2510
    • (1990) Cancer Res , vol.50 , Issue.8 , pp. 2505-2510
    • Shin, D.M.1    Gimenez, I.B.2    Lee, J.S.3    Nishioka, K.4    Wargovich, M.J.5    Thacher, S.6
  • 39
    • 65549155414 scopus 로고    scopus 로고
    • Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma
    • J.J. Sheu, C.H. Hua, L. Wan, Y.J. Lin, M.T. Lai, and H.C. Tseng Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma Cancer Res 69 6 2009 2568 2576
    • (2009) Cancer Res , vol.69 , Issue.6 , pp. 2568-2576
    • Sheu, J.J.1    Hua, C.H.2    Wan, L.3    Lin, Y.J.4    Lai, M.T.5    Tseng, H.C.6
  • 40
    • 79551711693 scopus 로고    scopus 로고
    • Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma
    • R.J. Leeman-Neill, R.R. Seethala, S.V. Singh, M.L. Freilino, J.S. Bednash, and S.M. Thomas Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma Cancer Prev Res (Phila) 4 2 2011 230 237
    • (2011) Cancer Prev Res (Phila) , vol.4 , Issue.2 , pp. 230-237
    • Leeman-Neill, R.J.1    Seethala, R.R.2    Singh, S.V.3    Freilino, M.L.4    Bednash, J.S.5    Thomas, S.M.6
  • 41
    • 84907873192 scopus 로고    scopus 로고
    • A phase II trial of cetuximab in high-risk premalignant lesions of the upper aerodigestive tract
    • [abstr. 5528]
    • J.A. Califano, R.L. Ferris, J.B. Epstein, M.B. Gillespie, L.E. Feldman, and M.K. Gibson A phase II trial of cetuximab in high-risk premalignant lesions of the upper aerodigestive tract J Clin Oncol 30 suppl. 2012 [abstr. 5528]
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Califano, J.A.1    Ferris, R.L.2    Epstein, J.B.3    Gillespie, M.B.4    Feldman, L.E.5    Gibson, M.K.6
  • 42
    • 0032556189 scopus 로고    scopus 로고
    • Phenotype and genotype of advanced premalignant head and neck lesions after chemopreventive therapy
    • L. Mao, A.K. El-Naggar, V. Papadimitrakopoulou, D.M. Shin, H.C. Shin, and Y. Fan Phenotype and genotype of advanced premalignant head and neck lesions after chemopreventive therapy J Natl Cancer Inst 90 20 1998 1545 1551
    • (1998) J Natl Cancer Inst , vol.90 , Issue.20 , pp. 1545-1551
    • Mao, L.1    El-Naggar, A.K.2    Papadimitrakopoulou, V.3    Shin, D.M.4    Shin, H.C.5    Fan, Y.6
  • 43
    • 59149101065 scopus 로고    scopus 로고
    • Randomized trial of 13-cis retinoic acid compared with retinyl palmitate with or without beta-carotene in oral premalignancy
    • V.A. Papadimitrakopoulou, J.J. Lee, W.N. William Jr., J.W. Martin, M. Thomas, and E.S. Kim Randomized trial of 13-cis retinoic acid compared with retinyl palmitate with or without beta-carotene in oral premalignancy J Clin Oncol 27 4 2009 599 604
    • (2009) J Clin Oncol , vol.27 , Issue.4 , pp. 599-604
    • Papadimitrakopoulou, V.A.1    Lee, J.J.2    William, W.N.3    Martin, J.W.4    Thomas, M.5    Kim, E.S.6
  • 44
    • 0029929885 scopus 로고    scopus 로고
    • Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment
    • L. Mao, J.S. Lee, Y.H. Fan, J.Y. Ro, J.G. Batsakis, and S. Lippman Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment Nat Med 2 6 1996 682 685
    • (1996) Nat Med , vol.2 , Issue.6 , pp. 682-685
    • Mao, L.1    Lee, J.S.2    Fan, Y.H.3    Ro, J.Y.4    Batsakis, J.G.5    Lippman, S.6
  • 45
    • 0033975644 scopus 로고    scopus 로고
    • Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia
    • M.P. Rosin, X. Cheng, C. Poh, W.L. Lam, Y. Huang, and J. Lovas Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia Clin Cancer Res 6 2 2000 357 362
    • (2000) Clin Cancer Res , vol.6 , Issue.2 , pp. 357-362
    • Rosin, M.P.1    Cheng, X.2    Poh, C.3    Lam, W.L.4    Huang, Y.5    Lovas, J.6
  • 46
    • 84866182142 scopus 로고    scopus 로고
    • Loss of heterozygosity (LOH) profiles-validated risk predictors for progression to oral cancer
    • L. Zhang, C.F. Poh, M. Williams, D.M. Laronde, K. Berean, and P.J. Gardner Loss of heterozygosity (LOH) profiles-validated risk predictors for progression to oral cancer Cancer Prev Res (Phila) 5 9 2012 1081 1089
    • (2012) Cancer Prev Res (Phila) , vol.5 , Issue.9 , pp. 1081-1089
    • Zhang, L.1    Poh, C.F.2    Williams, M.3    Laronde, D.M.4    Berean, K.5    Gardner, P.J.6
  • 47
    • 0037112440 scopus 로고    scopus 로고
    • 3p14 and 9p21 loss is a simple tool for predicting second oral malignancy at previously treated oral cancer sites
    • M.P. Rosin, W.L. Lam, C. Poh, N.D. Le, R.J. Li, and T. Zeng 3p14 and 9p21 loss is a simple tool for predicting second oral malignancy at previously treated oral cancer sites Cancer Res 62 22 2002 6447 6450
    • (2002) Cancer Res , vol.62 , Issue.22 , pp. 6447-6450
    • Rosin, M.P.1    Lam, W.L.2    Poh, C.3    Le, N.D.4    Li, R.J.5    Zeng, T.6
  • 48
    • 33745683516 scopus 로고    scopus 로고
    • Progress in chemoprevention drug development: The promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer-a plan to move forward
    • G.J. Kelloff, S.M. Lippman, A.J. Dannenberg, C.C. Sigman, H.L. Pearce, and B.J. Reid Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer-a plan to move forward Clin Cancer Res 12 12 2006 3661 3697
    • (2006) Clin Cancer Res , vol.12 , Issue.12 , pp. 3661-3697
    • Kelloff, G.J.1    Lippman, S.M.2    Dannenberg, A.J.3    Sigman, C.C.4    Pearce, H.L.5    Reid, B.J.6
  • 49
    • 5444275938 scopus 로고    scopus 로고
    • The convergence of cancer prevention and therapy in early-phase clinical drug development
    • J.L. Abbruzzese, and S.M. Lippman The convergence of cancer prevention and therapy in early-phase clinical drug development Cancer Cell 6 4 2004 321 326
    • (2004) Cancer Cell , vol.6 , Issue.4 , pp. 321-326
    • Abbruzzese, J.L.1    Lippman, S.M.2
  • 50
    • 84874914651 scopus 로고    scopus 로고
    • Chemoprevention of head and neck cancer by simultaneous blocking of epidermal growth factor receptor and cyclooxygenase-2 signaling pathways: Preclinical and clinical studies
    • D.M. Shin, H. Zhang, N.F. Saba, A.Y. Chen, S. Nannapaneni, and A.R. Amin Chemoprevention of head and neck cancer by simultaneous blocking of epidermal growth factor receptor and cyclooxygenase-2 signaling pathways: preclinical and clinical studies Clin Cancer Res 19 5 2013 1244 1256
    • (2013) Clin Cancer Res , vol.19 , Issue.5 , pp. 1244-1256
    • Shin, D.M.1    Zhang, H.2    Saba, N.F.3    Chen, A.Y.4    Nannapaneni, S.5    Amin, A.R.6
  • 51
    • 78649279329 scopus 로고    scopus 로고
    • Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis
    • G. Zhou, R. Hasina, K. Wroblewski, T.P. Mankame, C.L. Doci, and M.W. Lingen Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis Cancer Prev Res (Phila) 3 11 2010 1493 1502
    • (2010) Cancer Prev Res (Phila) , vol.3 , Issue.11 , pp. 1493-1502
    • Zhou, G.1    Hasina, R.2    Wroblewski, K.3    Mankame, T.P.4    Doci, C.L.5    Lingen, M.W.6


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