Pressure natriuresis and the renal control of arterial blood pressure

Journal of Physiology

Volumn 592, Issue 18, 2014, Pages 3955-3967

  Ivy, Jessica R ^a   Bailey, Matthew A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; SODIUM;

ARTERIAL PRESSURE; BLOOD PRESSURE REGULATION; DRUG EFFECT; EXTRACELLULAR SPACE; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; HEREDITARY HYPERTENSION; HUMAN; HYPERTENSION; INFLAMMATION; KIDNEY BLOOD FLOW; KIDNEY DENERVATION; KIDNEY FUNCTION; KIDNEY MEDULLA; KIDNEY PERFUSION; KIDNEY TRANSPLANTATION; KIDNEY TUBULE ABSORPTION; NATRIURESIS; NEPHRON; NONHUMAN; PATIENT COMPLIANCE; RADIOFREQUENCY ABLATION; RENAL SYMPATHETIC NERVE ACTIVITY; RENAL SYSTEM PARAMETERS; REVIEW; SODIUM URINE LEVEL; THERAPY EFFECT; ADRENERGIC SYSTEM; ANIMAL; BLOOD PRESSURE; GENETICS; INNERVATION; KIDNEY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; BLOOD PRESSURE; HUMANS; HYPERTENSION; KIDNEY; NATRIURESIS; SYMPATHETIC NERVOUS SYSTEM;

EID: 84907857737     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2014.271676     Document Type: Review

References (99)

1. Ashek A, Menzies RI, Mullins LJ, Bellamy CO, Harmar AJ, Kenyon CJ, Flatman PW, Mullins JJ & Bailey MA (2012). Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat. PLoS One 7, e36311.
2. Averina VA, Othmer HG, Fink GD & Osborn JW(2012). A new conceptual paradigm for the haemodynamics of salt-sensitive hypertension: a mathematical modelling approach. J Physiol 590, 5975-5992.
3. Bailey MA (2004). Inhibition of bicarbonate reabsorption in the rat proximal tubule by activation of luminal P2Y1 receptors. Am J Physiol Renal Physiol 287, F789-F796.
4. BaileyMA, Paterson JM,Hadoke PW, Wrobel N, Bellamy CO, Brownstein DG, Seckl JR & Mullins JJ (2008). A switch in the mechanism of hypertension in the syndrome of apparent mineralocorticoid excess. J Am Soc Nephrol 19, 47-58.
5. Bankir L, Bochud M, Maillard M, Bovet P, Gabriel A & Burnier M (2008). Nighttime blood pressure and nocturnal dipping are associated with daytime urinary sodium excretion in African subjects. Hypertension 51, 891-898.
6. Bhatt DL, Kandzari DE, O'Neill WW, D'Agostino R, Flack JM, Katzen BT, Leon MB, Liu M, Mauri L, Negoita M et al. (2014). A controlled trial of renal denervation for resistant hypertension. N Engl J Med 370, 1393-1401.
7. Biancardi VC, Son SJ, Ahmadi S, Filosa JA & Stern JE (2014). Circulating angiotensin II gains access to the hypothalamus and brain stem during hypertension via breakdown of the blood-brain barrier. Hypertension 63, 572-579.
8. Blaustein MP, Leenen FH, Chen L, Golovina VA, Hamlyn JM, Pallone TL, Van Huysse JW, Zhang J & WierWG (2012). How NaCl raises blood pressure: a new paradigm for the pathogenesis of salt-dependent hypertension. Am J Physiol Heart Circ Physiol 302, H1031-H1049.
9. Botero-Velez M, Curtis JJ & Warnock DG (1994). Brief report: Liddle's syndrome revisited-a disorder of sodium reabsorption in the distal tubule. N Engl J Med 330, 178-181.
10. Brenner BM, Garcia DL & Anderson S (1988). Glomeruli and blood pressure. Less of one, more the other? Am J Hypertens 1, 335-347.
11. Burchell AE, LoboMD, Sulke N, Sobotka PA & Paton JF (2014). Arteriovenous anastomosis: is this the way to control hypertension? Hypertension 64, 6-12.
12. Burnstock G, Evans LC & Bailey MA (2014). Purinergic signalling in the kidney in health and disease. Purinergic Signal 10, 71-101.
13. Campese VM & Kogosov E (1995). Renal afferent denervation prevents hypertension in rats with chronic renal failure. Hypertension 25, 878-882.
14. Cannon WB (1929). Organization for physiological homeostasis. Physiol Rev 9, 399-431.
15. Chandrashekar J, Kuhn C, Oka Y, Yarmolinsky DA, Hummler E, Ryba NJ & Zuker CS (2010). The cells and peripheral representation of sodium taste in mice. Nature 464, 297-301.
16. Chapman K, Holmes M & Seckl J (2013). 11ß-Hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action. Physiol Rev 93, 1139-1206.
17. Chobanian AV (2009). The hypertension paradox-more uncontrolled disease despite improved therapy. N Engl J Med 361, 878-887.
18. Crowley SD, Gurley SB, Herrera MJ, Ruiz P, Griffiths R, Kumar AP, Kim HS, Smithies O, Le TH & Coffman TM (2006). Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. Proc Natl Acad Sci U S A 103, 17985-17990.
19. Crowley SD, Song YS, Lin EE, Griffiths R, Kim HS & Ruiz P (2010). Lymphocyte responses exacerbate angiotensin II-dependent hypertension. Am J Physiol Regul Integr Comp Physiol 298, R1089-R1097.
20. Curtis JJ, Luke RG, Dustan HP, Kashgarian M,Whelchel JD, Jones P & Diethelm AG (1983). Remission of essential hypertension after renal transplantation. N Engl J Med 309, 1009-1015.
21. Dagan A, Gattineni J, Habib S & Baum M (2010). Effect of prenatal dexamethasone on postnatal serum and urinary angiotensin II levels. Am J Hypertens 23, 420-424.
22. Dagan A, Kwon HM, Dwarakanath V & Baum M (2008). Effect of renal denervation on prenatal programming of hypertension and renal tubular transporter abundance. Am J Physiol Renal Physiol 295, F29-F34.
23. Dautzenberg M, Keilhoff G & Just A (2011). Modulation of the myogenic response in renal blood flow autoregulation by NO depends on endothelial nitric oxide synthase (eNOS), but not neuronal or inducible NOS. J Physiol 589, 4731-4744.
24. DiBona GF & Kopp UC (1997). Neural control of renal function. Physiol Rev 77, 75-197.
25. Donazzan L, Mahfoud F, Linz D, Ewen S, Ukena C & Bohm M (2014). Novel and nonpharmacologic approaches to cardio-protection in hypertension. Curr Hypertens Rep 16, 430.
26. Eckardt KU, Coresh J, Devuyst O, Johnson RJ, Kottgen A, Levey AS & Levin A (2013). Evolving importance of kidney disease: from subspecialty to global health burden. Lancet 382, 158-169.
27. Ehret GB, O'Connor AA,Weder A, Cooper RS & Chakravarti A (2009). Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. Eur J Hum Genet 17, 1650-1657.
28. Esler MD, Krum H, Sobotka PA, Schlaich MP, Schmieder RE & Bohm M (2010). Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial. Lancet 376, 1903-1909.
29. Evans JG & Rose G (1971). Hypertension. Br Med Bull 27, 37-42.
30. Evans LC, Holmes MC, Mullins JJ & Bailey MA (2012a). Evaluation of salt appetite in brain specific 11 beta hydroxysteroid dehydrogenase type 2 knockout mice. FASEB J 26, Abstract.
31. Evans LC, Livingstone DE, Kenyon CJ, Jansen MA, Dear JW, Mullins JJ & Bailey MA (2012b). A urine-concentrating defect in 11ß-hydroxysteroid dehydrogenase type 2-null mice. Am J Physiol Renal Physiol 303, F494-F502.
32. Faber JE & Brody MJ (1985). Afferent renal nerve-dependent hypertension following acute renal artery stenosis in the conscious rat. Circ Res 57, 676-688.
33. Fadl Elmula FE,Hoffmann P, Fossum E, Brekke M, Gjonnaess E, Hjornholm U, Kjaer VN, Rostrup M, Kjeldsen SE, Os I et al. (2013). Renal sympathetic denervation in patients with treatment-resistant hypertension after witnessed intake of medication before qualifying ambulatory blood pressure. Hypertension 62, 526-532.
34. Fisher JP & Paton JF (2012). The sympathetic nervous system and blood pressure in humans: implications for hypertension. J HumHypertens 26, 463-475.
35. Franco M, Tapia E, Bautista R, Pacheco U, Santamaria J, Quiroz Y, Johnson RJ & Rodriguez-Iturbe B (2013). Impaired pressure natriuresis resulting in salt-sensitive hypertension is caused by tubulointerstitial immune cell infiltration in the kidney. Am J Physiol Renal Physiol 304, F982-F990.
36. Garcia-Estan J & Roman RJ (1989). Role of renal interstitial hydrostatic pressure in the pressure diuresis response. Am J Physiol Renal Physiol 256, F63-F70.
37. Garvin JL, Herrera M & Ortiz PA (2011). Regulation of renal NaCl transport by nitric oxide, endothelin, and ATP: clinical implications. Annu Rev Physiol 73, 359-376.
38. Gourine A, Bondar SI, Spyer KM & Gourine AV (2008). Beneficial effect of the central nervous system ß-adrenoceptor blockade on the failing heart. Circ Res 102, 633-636.
39. Graham LA, Padmanabhan S, Fraser NJ, Kumar S, Bates JM, Raffi HS,Welsh P, Beattie W, Hao S, Leh S et al. (2014). Validation of uromodulin as a candidate gene for human essential hypertension. Hypertension 63, 551-558.
40. Grisk O, Heukaufer M, Steinbach A, Gruska S & Rettig R (2004). Analysis of arterial pressure regulating systems in renal post-transplantation hypertension. J Hypertens 22, 199-207.
41. Grisk O, Rose HJ, Lorenz G & Rettig R (2002). Sympathetic-renal interaction in chronic arterial pressure control. Am J Physiol Regul Integr Comp Physiol 283, R441-R450.
42. Gurley SB, Riquier-Brison AD, Schnermann J, Sparks MA, Allen AM, Haase VH, Snouwaert JN, Le TH, McDonough AA, Koller BH & Coffman TM (2011). AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure. Cell Metab 13, 469-475.
43. Guyton AC, Coleman TG & Granger HJ (1972). Circulation: overall regulation. Annu Rev Physiol 34, 13-46.
44. Guzik TJ, Hoch NE, Brown KA, McCann LA, Rahman A, Dikalov S, Goronzy J,Weyand C & Harrison DG (2007). Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction. J ExpMed 204, 2449-2460.
45. Haas JA, Granger JP & Knox FG (1986). Effect of renal perfusion pressure on sodium reabsorption from proximal tubules of superficial and deep nephrons. Am J Physiol Renal Physiol 250, F425-F429.
46. Hall JE, Mizelle HL,Woods LL & Montani JP (1988). Pressure natriuresis and control of arterial pressure during chronic norepinephrine infusion. J Hypertens 6, 723-731.
47. Harrap SB, Stebbing M, Hopper JL, Hoang HN & Giles GG (2000). Familial patterns of covariation for cardiovascular risk factors in adults: The Victorian Family Heart Study. Am J Epidemiol 152, 704-715.
48. Hart EC, McBryde FD, Burchell AE, Ratcliffe LE, Stewart LQ, Baumbach A, Nightingale A & Paton JF (2013). Translational examination of changes in baroreflex function after renal denervation in hypertensive rats and humans. Hypertension 62, 533-541.
49. Hermida RC, Ayala DE, Smolensky MH, Fernandez JR, Mojon A, Crespo JJ, Rios MT, Moya A & Portaluppi F (2014). Chronotherapeutics of conventional blood pressure-lowering medications: simple, low-cost means of improving management and treatment outcomes of hypertensive-related disorders. Curr Hypertens Rep 16, 412.
50. Hester RL, Brown AJ, Husband L, Iliescu R, Pruett D, Summers R & Coleman TG (2011). HumMod: a modeling environment for the simulation of integrative human physiology. Front Physiol 2, 12.
51. Howard JP, Nowbar AN & Francis DP (2013). Size of blood pressure reduction from renal denervation: insights from meta-analysis of antihypertensive drug trials of 4,121 patients with focus on trial design: the CONVERGE report. Heart 99, 1579-1587.
52. Hunter RW, Ivy JR & Bailey MA (2014). Glucocorticoids and renal sodium transport: implications for hypertension and salt sensitivity. J Physiol. 592:1731-1744.
53. Huysmans FT, van Heusden FH,Wetzels JF, Hoitsma AJ & Koene RA (1988). Antihypertensive effect of beta blockade in renal transplant recipients with or without host kidneys. Transplantation 46, 234-237.
54. Johns EJ (2014). The neural regulation of the kidney in hypertension and renal failure. Exp Physiol 99, 289-294.
55. Johns EJ, Kopp UC & DiBona GF (2011). Neural control of renal function. Compr Physiol 1, 731-767.
56. Judge SJ & Dorrington KL (2013). Unsupported assumption in model of salt-sensitive hypertension. J Physiol 591, 2963.
57. Katholi RE, Naftilan AJ, Bishop SP & Oparil S (1983). Role of the renal nerves in the maintenance of DOCA-salt hypertension in the rat. Influence on the renal vasculature and sodium excretion. Hypertension 5, 427-435.
58. Kearney PM,Whelton M, Reynolds K, Muntner P,Whelton PK & He J (2005). Global burden of hypertension: analysis of worldwide data. Lancet 365, 217-223.
59. Khattab AM, Shackleton CH, Hughes BA, Bodalia JB & New MI (2014). Remission of hypertension and electrolyte abnormalities following renal transplantation in a patient with apparent mineralocorticoid excess well documented throughout childhood. J Pediatr Endocrinol Metab 27, 17-21.
60. Kleinewietfeld M, Manzel A, Titze J, Kvakan H, Yosef N, Linker RA, Muller DN & Hafler DA (2013). Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature 496, 518-522.
61. Kopf D,Waldherr R & Rettig R (1993). Source of kidney determines blood pressure in young renal transplanted rats. Am J Physio Renal Physioll 265, F104-F111.
62. Krum H, Schlaich MP, Sobotka PA, Bohm M, Mahfoud F, Rocha-Singh K, Katholi R & Esler MD (2014). Percutaneous renal denervation in patients with treatment-resistant hypertension: final 3-year report of the Symplicity HTN-1 study. Lancet 383, 622-629.
63. Krum H, Schlaich M,Whitbourn R, Sobotka PA, Sadowski J, Bartus K, Kapelak B,Walton A, Sievert H, Thambar S et al. (2009). Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study. Lancet 373, 1275-1281.
64. Kubota J, Nishimura H, Ueyama M & Kawamura K (1993). Effects of renal denervation on pressure-natriuresis in spontaneously hypertensive rats. Jpn Circ J 57, 1097-1105.
65. Lewington S, Clarke R, Qizilbash N, Peto R & Collins R (2002). Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 360, 1903-1913.
66. Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, Amann M, Anderson HR, Andrews KG, Aryee M et al. (2012). A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380, 2224-2260.
67. McDonough AA (2010). Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure. Am J Physiol Regul Integr Comp Physiol 298, R851-R861.
68. Machnik A, NeuhoferW, Jantsch J, Dahlmann A, Tammela T, Machura K, Park JK, Beck FX, Muller DN, DererWet al. (2009). Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med 15, 545-552.
69. McHugh MI, Tanboga H, Marcen R, Liano F, Robson V & Wilkinson R (1980). Hypertension following renal transplantation: the role of the host's kidney. Q J Med 49, 395-403.
70. Malsure S, Wang Q, Charles RP, Sergi C, Perrier R, Christensen BM, Maillard M, Rossier BC & Hummler E (2014). Colon-specific deletion of epithelial sodium channel causes sodium loss and aldosterone resistance. J Am Soc Nephrol. 25, 1453-1464.
71. Marvar PJ, Thabet SR, Guzik TJ, Lob HE,McCann LA,Weyand C, Gordon FJ & Harrison DG (2010). Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. Circ Res 107, 263-270.
72. Mullins LJ, Bailey MA & Mullins JJ (2006). Hypertension, kidney, and transgenics: a fresh perspective. Physiol Rev 86, 709-746.
73. Nguyen MT, Lee DH, Delpire E & McDonough AA (2013). Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition. Am J Physiol Renal Physiol 305, F510-F519.
74. O'Connor PM & Cowley AW Jr (2010). Modulation of pressure-natriuresis by renal medullary reactive oxygen species and nitric oxide. Curr Hypertens Rep 12, 86-92.
75. Padmanabhan S, Melander O, Johnson T, Di Blasio AM, Lee WK, Gentilini D, Hastie CE, Menni C, Monti MC, Delles C et al. (2010). Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet 6, e1001177.
76. Padmanabhan S, Newton-Cheh C & Dominiczak AF (2012). Genetic basis of blood pressure and hypertension. Trends Genet 28, 397-408.
77. Peacock J, Diaz KM, Viera AJ, Schwartz JE & Shimbo D (2014). Unmasking masked hypertension: prevalence, clinical implications, diagnosis, correlates and future directions. J HumHypertens 28, 521-528.
78. Pons H, Ferrebuz A, Quiroz Y, Romero-Vasquez F, Parra G, Johnson RJ & Rodriguez-Iturbe B (2013). Immune reactivity to heat shock protein 70 expressed in the kidney is cause of salt-sensitive hypertension. Am J Physiol Renal Physiol 304, F289-F299.
79. Rampoldi L, Scolari F, Amoroso A, Ghiggeri G & Devuyst O (2011). The rediscovery of uromodulin (Tamm-Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease. Kidney Int 80, 338-347.
80. Rettig R, Folberth C, Stauss H, Kopf D,Waldherr R & Unger T (1990). Role of the kidney in primary hypertension: a renal transplantation study in rats. Am J Physiol Renal Physiol 258, F606-F611.
81. Rettig R & Grisk O (2005). The kidney as a determinant of genetic hypertension: evidence from renal transplantation studies. Hypertension 46, 463-468.
82. Rodriguez-Iturbe B, Pons H, Quiroz Y, Lanaspa MA & Johnson RJ (2014). Autoimmunity in the pathogenesis of hypertension. Nat Rev Nephrol 10, 56-62.
83. Roman RJ (1988). Pressure-diuresis in volume-expanded rats. Tubular reabsorption in superficial and deep nephrons. Hypertension 12, 177-183.
84. Roman RJ, Cowley AW Jr, Garcia-Estan J & Lombard JH (1988). Pressure-diuresis in volume-expanded rats. Cortical and medullary hemodynamics. Hypertension 12, 168-176.
85. Roman RJ & Kaldunski ML (1988). Renal cortical and papillary blood flow in spontaneously hypertensive rats. Hypertension 11, 657-663.
86. Rudemiller N, Lund H, Jacob HJ, Geurts AM & Mattson DL (PhysGen Knockout Program)(2014). CD247 modulates blood pressure by altering T-lymphocyte infiltration in the kidney. Hypertension 63, 559-564.
87. Schafer JA (1990). Transepithelial osmolality differences, hydraulic conductivities, and volume absorption in the proximal tubule. Annu Rev Physiol 52, 709-726.
88. Schlaich MP, Sobotka PA, Krum H, Lambert E & Esler MD (2009). Renal sympathetic-nerve ablation for uncontrolled hypertension. N Engl J Med 361, 932-934.
89. Sega R, Facchetti R, Bombelli M, Cesana G, Corrao G, Grassi G & Mancia G (2005). Prognostic value of ambulatory and home blood pressures compared with office blood pressure in the general population: follow-up results from the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study. Circulation 111, 1777-1783.
90. Terker AS, Yang CL, McCormick JA, Meermeier NP, Rogers SL, Grossmann S, Trompf K, Delpire E, Loffing J & Ellison DH (2014). Sympathetic stimulation of thiazide-sensitive sodium chloride cotransport in the generation of salt-sensitive hypertension. Hypertension 64, 178-184.
91. Toprak A,Wang H, Chen W, Paul T, Ruan L, Srinivasan S & Berenson G (2009). Prehypertension and black-white contrasts in cardiovascular risk in young adults: Bogalusa Heart Study. J Hypertens 27, 243-250.
92. Wadei HM & Textor SC (2012). The role of the kidney in regulating arterial blood pressure. Nat Rev Nephrol 8, 602-609.
93. Warnock DG, Kusche-Vihrog K, Tarjus A, Sheng S, Oberleithner H, Kleyman TR & Jaisser F (2014). Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells. Nat Rev Nephrol 10, 146-157.
94. Wellcome Trust Case Control Consortium (2007). Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678.
95. Wiig H, Schroder A, Neuhofer W, Jantsch J, Kopp C, Karlsen TV, Boschmann M, Goss J, Bry M, Rakova N et al. (2013). Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. J Clin Invest 123, 2803-2815.
96. Winternitz SR, Katholi RE & Oparil S (1980). Role of the renal sympathetic nerves in the development and maintenance of hypertension in the spontaneously hypertensive rat. J Clin Invest 66, 971-978.
97. Xue B, Beltz TG, Yu Y, Guo F, Gomez-Sanchez CE, Hay M & Johnson AK (2011). Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. Am J Physiol Heart Circ Physiol 300, H555-H564.
98. Ye S, Zhong H, Yanamadala V & Campese VM (2002). Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity. Am J Hypertens 15, 717-724.
99. Zubcevic J,Waki H, Raizada MK & Paton JFR (2011). Autonomic-immune-vascular interaction: an emerging concept for neurogenic hypertension. Hypertension 57, 1026-1033.