A thermostable salmonella phage endolysin, Lys68, with broad bactericidal properties against gram-negative pathogens in presence of weak acids

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Oliveira, Hugo ^a   Thiagarajan, Viruthachalam ^b   Walmagh, Maarten ^c   Sillankorva, Sanna ^a   Lavigne, Rob ^c   Neves Petersen, Maria Teresa ^d,e   Kluskens, Leon D ^a   Azeredo, Joana ^a  

^a UNIVERSITY OF MINHO   (Portugal)

^b BHARATHIDASAN UNIVERSITY   (India)

^c LABORATORY OF GENE TECHNOLOGY   (Belgium)

^d INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATORY   (Portugal)

^e AALBORG UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; BACTERICIDE; CITRIC ACID; EDETIC ACID; MALIC ACID; SALMONELLA PHAGE ENDOLYSIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ENDOLYSIN; MALIC ACID DERIVATIVE; PROTEINASE;

ARTICLE; BACTERIAL LOAD; BACTERIAL OUTER MEMBRANE; BACTERICIDAL ACTIVITY; BIOFILM; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; GRAM NEGATIVE BACTERIUM; MEMBRANE DAMAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PROTEIN REFOLDING; PSEUDOMONAS; SALMONELLA TYPHIMURIUM; THERMOSTABILITY; CELL MEMBRANE PERMEABILITY; CHEMISTRY; DRUG EFFECTS; ENZYME STABILITY; GENETICS; HYDROLYSIS; METABOLISM; SALMONELLA PHAGE; THERMODYNAMICS;

NEGIBACTERIA; SALMONELLA;

ANTI-BACTERIAL AGENTS; CELL MEMBRANE PERMEABILITY; CITRIC ACID; ENDOPEPTIDASES; ENZYME STABILITY; GRAM-NEGATIVE BACTERIA; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MALATES; SALMONELLA PHAGES; THERMODYNAMICS;

EID: 84907855839     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108376     Document Type: Article

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