-
1
-
-
34249820803
-
Hsp90: A novel target for the disruption of multiple signaling cascades
-
Bishop SC, Burlison JA and Blagg BS: Hsp90: a novel target for the disruption of multiple signaling cascades. Curr Cancer Drug Targets 7: 369-388, 2007.
-
(2007)
Curr Cancer Drug Targets
, vol.7
, pp. 369-388
-
-
Bishop, S.C.1
Burlison, J.A.2
Blagg, B.S.3
-
4
-
-
84889579193
-
The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide
-
Lee WY, Chen YC, Shih CM, et al: The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide. Toxicol Appl Pharmacol 274: 55-62, 2014.
-
(2014)
Toxicol Appl Pharmacol
, vol.274
, pp. 55-62
-
-
Lee, W.Y.1
Chen, Y.C.2
Shih, C.M.3
-
5
-
-
38049094510
-
Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo
-
Schwock J, Pham NA, Cao MP and Hedley DW: Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo. Cancer Chemother Pharmacol 61: 669-681, 2008.
-
(2008)
Cancer Chemother Pharmacol
, vol.61
, pp. 669-681
-
-
Schwock, J.1
Pham, N.A.2
Cao, M.P.3
Hedley, D.W.4
-
6
-
-
33645975518
-
Chaperoning oncogenes: Hsp90 as a target of geldanamycin
-
Neckers L: Chaperoning oncogenes: Hsp90 as a target of geldanamycin. Handb Exp Pharmacol 172: 259-277, 2006.
-
(2006)
Handb Exp Pharmacol
, vol.172
, pp. 259-277
-
-
Neckers, L.1
-
7
-
-
78549234304
-
A novel class of specific Hsp90 small molecule inhibitors demonstrate in vitro and in vivo anti-tumor activity in human melanoma cells
-
Mehta PP, Kung PP, Yamazaki S, et al: A novel class of specific Hsp90 small molecule inhibitors demonstrate in vitro and in vivo anti-tumor activity in human melanoma cells. Cancer Lett 300: 30-39, 2011.
-
(2011)
Cancer Lett
, vol.300
, pp. 30-39
-
-
Mehta, P.P.1
Kung, P.P.2
Yamazaki, S.3
-
8
-
-
84907854408
-
Study on the cell signal transductions of cell proliferation and apoptosis induced by VEGF-C in cervical carcinoma
-
Du X and Mi R: Study on the cell signal transductions of cell proliferation and apoptosis induced by VEGF-C in cervical carcinoma. Xian Dai Fu Chan Ke Za Zhi 11: 877-880, 885, 2011.
-
(2011)
Xian Dai Fu Chan Ke Za Zhi
, vol.11
-
-
Du, X.1
Mi, R.2
-
9
-
-
29244492286
-
Radiation and new molecular agents, part II: Targeting HDAC, HSP90, IGF-1R, PI3K, and Ras
-
Chinnaiyan P, Allen GW and Harari PM: Radiation and new molecular agents, part II: targeting HDAC, HSP90, IGF-1R, PI3K, and Ras. Semin Radiat Oncol 16: 59-64, 2006.
-
(2006)
Semin Radiat Oncol
, vol.16
, pp. 59-64
-
-
Chinnaiyan, P.1
Allen, G.W.2
Harari, P.M.3
-
10
-
-
0038637205
-
The heat shock protein 90-binding geldanamycin inhibits cancer cell proliferation, down-regulates oncoproteins, and inhibits epidermal growth factor-induced invasion in thyroid cancer cell lines
-
Park JW, Yeh MW, Wong MG, et al: The heat shock protein 90-binding geldanamycin inhibits cancer cell proliferation, down-regulates oncoproteins, and inhibits epidermal growth factor-induced invasion in thyroid cancer cell lines. J Clin Endocrinol Metab 88: 3346-3353, 2003.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 3346-3353
-
-
Park, J.W.1
Yeh, M.W.2
Wong, M.G.3
-
11
-
-
1642268986
-
Hsp90 isoforms: Functions, expression and clinical importance
-
Sreedhar AS, Kalmár E, Csermely P and Shen YF: Hsp90 isoforms: functions, expression and clinical importance. FEBS Lett 562: 11-15, 2004.
-
(2004)
FEBS Lett
, vol.562
, pp. 11-15
-
-
Sreedhar, A.S.1
Kalmár, E.2
Csermely, P.3
Shen, Y.F.4
-
12
-
-
33845913216
-
Intracellular and extracellular functions of heat shock proteins: Repercussions in cancer therapy
-
Schmitt E, Gehrmann M, Brunet M, Multhoff G and Garrido C: Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy. J Leukoc Biol 81: 15-27, 2007.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 15-27
-
-
Schmitt, E.1
Gehrmann, M.2
Brunet, M.3
Multhoff, G.4
Garrido, C.5
-
13
-
-
84879098944
-
ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system
-
Polier S, Samant RS, Clarke PA, et al: ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system. Nat Chem Biol 9: 307-312, 2013.
-
(2013)
Nat Chem Biol
, vol.9
, pp. 307-312
-
-
Polier, S.1
Samant, R.S.2
Clarke, P.A.3
-
14
-
-
0034892432
-
Hsp90: Chaperoning signal transduction
-
Richter K and Buchner J: Hsp90: chaperoning signal transduction. J Cell Physiol 188: 281-290, 2001.
-
(2001)
J Cell Physiol
, vol.188
, pp. 281-290
-
-
Richter, K.1
Buchner, J.2
-
15
-
-
27744520377
-
The expression of HSP60 and HSP10 in large bowel carcinomas with lymph node metastase
-
Cappello F, David S, Rappa F, et al: The expression of HSP60 and HSP10 in large bowel carcinomas with lymph node metastase. BMC Cancer 5: 139, 2005.
-
(2005)
BMC Cancer
, vol.5
, pp. 139
-
-
Cappello, F.1
David, S.2
Rappa, F.3
-
16
-
-
33846861747
-
Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors
-
Powers MV and Workman P: Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors. Endocr Relat Cancer 13 (Suppl 1): 125-135, 2006.
-
(2006)
Endocr Relat Cancer
, vol.13
, pp. 125-135
-
-
Powers, M.V.1
Workman, P.2
-
17
-
-
31544454764
-
Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death
-
Georgakis GV, Li Y, Rassidakis GZ, et al: Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death. Clin Cancer Res 12: 584-590, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 584-590
-
-
Georgakis, G.V.1
Li, Y.2
Rassidakis, G.Z.3
-
18
-
-
31544436323
-
Antimyeloma activity of heat shock protein-90 inhibition
-
Mitsiades CS, Mitsiades NS, McMullan CJ, et al: Antimyeloma activity of heat shock protein-90 inhibition. Blood 107: 1092-1100, 2006.
-
(2006)
Blood
, vol.107
, pp. 1092-1100
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.J.3
-
19
-
-
34250380627
-
Survivin, a member of the inhibitor of apoptosis family, is induced by photodynamic therapy and is a target for improving treatment response
-
Ferrario A, Rucker N, Wong S, Luna M and Gomer CJ: Survivin, a member of the inhibitor of apoptosis family, is induced by photodynamic therapy and is a target for improving treatment response. Cancer Res 67: 4989-4995, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 4989-4995
-
-
Ferrario, A.1
Rucker, N.2
Wong, S.3
Luna, M.4
Gomer, C.J.5
-
20
-
-
84876707777
-
The chaperone Hsp90: Changing partners for demanding clients
-
Röhl A, Rohrberg J and Buchner J: The chaperone Hsp90: changing partners for demanding clients. Trends Biochem Sci 38: 253-262, 2013.
-
(2013)
Trends Biochem Sci
, vol.38
, pp. 253-262
-
-
Röhl, A.1
Rohrberg, J.2
Buchner, J.3
-
21
-
-
84901257251
-
HSP90 Inhibitors: Current development and potential in cancer therapy
-
Sidera K and Patsavoudi E: HSP90 Inhibitors: current development and potential in cancer therapy. Recent Pat Anticancer Drug Discov 9: 1-20, 2014.
-
(2014)
Recent Pat Anticancer Drug Discov
, vol.9
, pp. 1-20
-
-
Sidera, K.1
Patsavoudi, E.2
-
22
-
-
33646725129
-
A biochemical rationale for the anticancer effects of Hsp90 inhibitors: Slow, tight binding inhibition by geldanamycin and its analogues
-
Gooljarsingh LT, Fernandes C, Yan K, et al: A biochemical rationale for the anticancer effects of Hsp90 inhibitors: slow, tight binding inhibition by geldanamycin and its analogues. Proc Natl Acad Sci USA 103: 7625-7630, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7625-7630
-
-
Gooljarsingh, L.T.1
Fernandes, C.2
Yan, K.3
-
23
-
-
33747679267
-
Analysis of expression of heat shock protein-90 (HSP90) and the effects of HSP90 inhibitor (17-AAG) in multiple myeloma
-
Duus J, Bahar HI, Venkataraman G, et al: Analysis of expression of heat shock protein-90 (HSP90) and the effects of HSP90 inhibitor (17-AAG) in multiple myeloma. Leuk Lymphoma 47: 1369-1378, 2006.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 1369-1378
-
-
Duus, J.1
Bahar, H.I.2
Venkataraman, G.3
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