메뉴 건너뛰기




Volumn 44, Issue 9, 2014, Pages 2802-2810

Dendritic cell-based therapeutic vaccine elicits polyfunctional HIV-specific T-cell immunity associated with control of viral load

(18)  Lévy, Yves a,b,c,d   Thiébaut, Rodolphe a,d,e,f   Montes, Monica d,g,h   Lacabaratz, Christine a,b,d   Sloan, Louis g,i   King, Bryan i   Pérusat, Sophie a,e   Harrod, Carson d,g,h   Cobb, Amanda g,h   Roberts, Lee K g   Surenaud, Mathieu a,b,d   Boucherie, Céline a   Zurawski, Sandra d,g,h   Delaugerre, Constance j   Richert, Laura a,d,e,f   Cĥene, Geneviève a,d,e   Banchereau, Jacques a,b,d,g,h,k   Palucka, Karolina d,g,h  

a INSERM   (France)
f INRIA   (France)

Author keywords

Antiretroviral therapy interruption; Dendritic cell; Lipopeptides; T cells; Vaccination

Indexed keywords

CYTOKINE; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; LIPOPEPTIDE;

EID: 84907841767     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201344433     Document Type: Article
Times cited : (97)

References (29)
  • 2
    • 63849131879 scopus 로고    scopus 로고
    • Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
    • Scheid, J. F., Mouquet, H., Feldhahn, N., Seaman, M. S., Velinzon, K., Pietzsch, J., Ott, R. G. et al., Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature. 2009. 458: 636-640.
    • (2009) Nature , vol.458 , pp. 636-640
    • Scheid, J.F.1    Mouquet, H.2    Feldhahn, N.3    Seaman, M.S.4    Velinzon, K.5    Pietzsch, J.6    Ott, R.G.7
  • 4
    • 40049085127 scopus 로고    scopus 로고
    • Preparation for antiretroviral interruption by boosting the immune system
    • Levy, Y., Preparation for antiretroviral interruption by boosting the immune system. Curr. Opin. HIV AIDS. 2008. 3: 118-123.
    • (2008) Curr. Opin. HIV AIDS. , vol.3 , pp. 118-123
    • Levy, Y.1
  • 5
    • 80051668754 scopus 로고    scopus 로고
    • Challenges in dendritic cells-based therapeutic vaccination in HIV-1 infection Workshop in dendritic cell-based vaccine clinical trials in HIV-1
    • Garcia, F. and Routy, J. P., Challenges in dendritic cells-based therapeutic vaccination in HIV-1 infection Workshop in dendritic cell-based vaccine clinical trials in HIV-1. Vaccine 2011. 29: 6454-6463.
    • (2011) Vaccine , vol.29 , pp. 6454-6463
    • Garcia, F.1    Routy, J.P.2
  • 6
    • 11144283687 scopus 로고    scopus 로고
    • Therapeutic dendritic-cell vaccine for chronic HIV-1 infection
    • Lu, W., Arraes, L. C., Ferreira, W. T. and Andrieu, J. M., Therapeutic dendritic-cell vaccine for chronic HIV-1 infection. Nat. Med. 2004. 10: 1359-1365.
    • (2004) Nat. Med. , vol.10 , pp. 1359-1365
    • Lu, W.1    Arraes, L.C.2    Ferreira, W.T.3    Andrieu, J.M.4
  • 7
    • 84872037286 scopus 로고    scopus 로고
    • A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication
    • Garcia, F., Climent, N., Guardo, A. C., Gil, C., Leon, A., Autran, B., Lifson, J. D. et al., A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication. Sci. Transl. Med. 2013. 5: 166ra2.
    • (2013) Sci. Transl. Med. , vol.5
    • Garcia, F.1    Climent, N.2    Guardo, A.C.3    Gil, C.4    Leon, A.5    Autran, B.6    Lifson, J.D.7
  • 8
    • 84857045791 scopus 로고    scopus 로고
    • mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients
    • Van Gulck, E., Vlieghe, E., Vekemans, M., Van Tendeloo, V. F., Van De Velde, A., Smits, E., Anguille, S. et al.,mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients. AIDS 2012. 26: F1-12.
    • (2012) AIDS , vol.26 , pp. F1-12
    • Van Gulck, E.1    Vlieghe, E.2    Vekemans, M.3    Van Tendeloo, V.F.4    Van De Velde, A.5    Smits, E.6    Anguille, S.7
  • 10
    • 4043060710 scopus 로고    scopus 로고
    • Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know
    • Pantaleo, G. and Koup, R. A., Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know. Nat. Med. 2004. 10: 806-810.
    • (2004) Nat. Med. , vol.10 , pp. 806-810
    • Pantaleo, G.1    Koup, R.A.2
  • 11
    • 33646380363 scopus 로고    scopus 로고
    • Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases
    • Pantaleo, G. and Harari, A., Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases. Nat. Rev. Immunol. 2006. 6: 417-423.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 417-423
    • Pantaleo, G.1    Harari, A.2
  • 12
    • 37049027525 scopus 로고    scopus 로고
    • Preserved central memory and activated effector memory CD4+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study
    • Potter, S. J., Lacabaratz, C., Lambotte, O., Perez-Patrigeon, S., Vingert, B., Sinet, M., Colle, J. H. et al., Preserved central memory and activated effector memory CD4+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study. J. Virol. 2007. 81: 13904-13915.
    • (2007) J. Virol. , vol.81 , pp. 13904-13915
    • Potter, S.J.1    Lacabaratz, C.2    Lambotte, O.3    Perez-Patrigeon, S.4    Vingert, B.5    Sinet, M.6    Colle, J.H.7
  • 13
    • 34249852256 scopus 로고    scopus 로고
    • HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
    • Saez-Cirion, A., Lacabaratz, C., Lambotte, O., Versmisse, P., Urrutia, A., Boufassa, F., Barre-Sinoussi, F. et al., HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype. Proc. Natl. Acad. Sci. U S A 2007. 104: 6776-6781.
    • (2007) Proc. Natl. Acad. Sci. U S A , vol.104 , pp. 6776-6781
    • Saez-Cirion, A.1    Lacabaratz, C.2    Lambotte, O.3    Versmisse, P.4    Urrutia, A.5    Boufassa, F.6    Barre-Sinoussi, F.7
  • 14
    • 79551690940 scopus 로고    scopus 로고
    • Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers
    • Williams, L. D., Bansal, A., Sabbaj, S., Heath, S. L., Song, W., Tang, J., Zajac, A. J. et al., Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers. J. Virol. 2011. 85: 2316-2324.
    • (2011) J. Virol. , vol.85 , pp. 2316-2324
    • Williams, L.D.1    Bansal, A.2    Sabbaj, S.3    Heath, S.L.4    Song, W.5    Tang, J.6    Zajac, A.J.7
  • 15
    • 67649234772 scopus 로고    scopus 로고
    • IL-21R on T cells is critical for sustained functionality and control of chronic viral infection
    • Frohlich, A., Kisielow, J., Schmitz, I., Freigang, S., Shamshiev, A. T., Weber, J., Marsland, B. J. et al., IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science (80). 2009. 324: 1576-1580.
    • (2009) Science , vol.80 , Issue.324 , pp. 1576-1580
    • Frohlich, A.1    Kisielow, J.2    Schmitz, I.3    Freigang, S.4    Shamshiev, A.T.5    Weber, J.6    Marsland, B.J.7
  • 16
    • 4644249757 scopus 로고    scopus 로고
    • Loss of HIV-1-specific CD8(+) T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4(+) T cells
    • Lichterfeld, M., Kaufmann, D. E., Yu, X. G., Mui, S. K.,Addo, M. M., Johnston, M. N., Cohen, D. et al., Loss of HIV-1-specific CD8(+) T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4(+) T cells. J. Exp. Med. 2004. 200: 701-712.
    • (2004) J. Exp. Med. , vol.200 , pp. 701-712
    • Lichterfeld, M.1    Kaufmann, D.E.2    Yu, X.G.3    Mui, S.K.4    Addo, M.M.5    Johnston, M.N.6    Cohen, D.7
  • 17
    • 4644271443 scopus 로고    scopus 로고
    • CD4+ T cells are required for the maintenance, not programming, ofmemory CD8+ T cells after acute infection
    • Sun, J. C., Williams, M. A. and Bevan, M. J., CD4+ T cells are required for the maintenance, not programming, ofmemory CD8+ T cells after acute infection. Nat. Immunol. 2004. 5: 927-933.
    • (2004) Nat. Immunol. , vol.5 , pp. 927-933
    • Sun, J.C.1    Williams, M.A.2    Bevan, M.J.3
  • 18
    • 0032418812 scopus 로고    scopus 로고
    • The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses
    • Kalams, S. A. and Walker, B. D., The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses. J. Exp. Med. 1998. 188: 2199-2204.
    • (1998) J. Exp. Med. , vol.188 , pp. 2199-2204
    • Kalams, S.A.1    Walker, B.D.2
  • 20
    • 0036839574 scopus 로고    scopus 로고
    • Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses
    • Hel, Z., Nacsa, J., Tryniszewska, E., Tsai, W. P., Parks, R. W., Montefiori, D. C., Felber, B. K. et al., Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses. J. Immunol. 2002. 169: 4778-4787.
    • (2002) J. Immunol. , vol.169 , pp. 4778-4787
    • Hel, Z.1    Nacsa, J.2    Tryniszewska, E.3    Tsai, W.P.4    Parks, R.W.5    Montefiori, D.C.6    Felber, B.K.7
  • 22
    • 77954080011 scopus 로고    scopus 로고
    • Perforin expression directly ex vivo by HIVspecific CD8 T-cells is a correlate of HIV elite control
    • Hersperger, A. R., Pereyra, F., Nason, M., Demers, K., Sheth, P., Shin, L. Y., Kovacs, C. M. et al., Perforin expression directly ex vivo by HIVspecific CD8 T-cells is a correlate of HIV elite control. PLoS Pathog. 2010. 6: e1000917.
    • (2010) PLoS Pathog , vol.6
    • Hersperger, A.R.1    Pereyra, F.2    Nason, M.3    Demers, K.4    Sheth, P.5    Shin, L.Y.6    Kovacs, C.M.7
  • 23
    • 77956608213 scopus 로고    scopus 로고
    • Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR
    • Klechevsky, E., Flamar, A. L., Cao, Y., Blanck, J. P., Liu, M., O'Bar, A., Agouna-Deciat, O. et al., Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR. Blood 2010. 116: 1685-1697.
    • (2010) Blood , vol.116 , pp. 1685-1697
    • Klechevsky, E.1    Flamar, A.L.2    Cao, Y.3    Blanck, J.P.4    Liu, M.5    O'Bar, A.6    Agouna-Deciat, O.7
  • 24
    • 0342647378 scopus 로고    scopus 로고
    • Multiepitopic B- and T-cell responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine
    • Gahery-Segard, H., Pialoux, G., Charmeteau, B., Sermet, S., Poncelet, H., Raux, M., Tartar, A. et al., Multiepitopic B- and T-cell responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine. J. Virol. 2000. 74: 1694-1703.
    • (2000) J. Virol. , vol.74 , pp. 1694-1703
    • Gahery-Segard, H.1    Pialoux, G.2    Charmeteau, B.3    Sermet, S.4    Poncelet, H.5    Raux, M.6    Tartar, A.7
  • 25
    • 84859101981 scopus 로고    scopus 로고
    • Effect of intermittent interleukin-2 therapy on CD4+ T-cell counts following antiretroviral cessation in patients with HIV
    • Levy, Y., Thiebaut, R., Gougeon, M. L., Molina, J. M., Weiss, L., Girard, P. M., Venet, A. et al., Effect of intermittent interleukin-2 therapy on CD4+ T-cell counts following antiretroviral cessation in patients with HIV. AIDS. 2012. 26: 711-720.
    • (2012) AIDS , vol.26 , pp. 711-720
    • Levy, Y.1    Thiebaut, R.2    Gougeon, M.L.3    Molina, J.M.4    Weiss, L.5    Girard, P.M.6    Venet, A.7
  • 26
    • 20144381894 scopus 로고    scopus 로고
    • Immunological and virological efficacy of a therapeutic immunization combined with interleukin-2 in chronically HIV-1 infected patients
    • Levy, Y., Gahery Segard, H., Durier, C., Lascaux, A. S., Goujard, C., Meiffredy, V., Rouzioux, C. et al., Immunological and virological efficacy of a therapeutic immunization combined with interleukin-2 in chronically HIV-1 infected patients. AIDS. 2005. 19: 279-286.
    • (2005) AIDS , vol.19 , pp. 279-286
    • Levy, Y.1    Gahery Segard, H.2    Durier, C.3    Lascaux, A.S.4    Goujard, C.5    Meiffredy, V.6    Rouzioux, C.7
  • 28
    • 0035733108 scopus 로고    scopus 로고
    • The control of the false discovery rate in multiple testing under dependency
    • Benjamini, Y. and Yekutieli, D., The control of the false discovery rate in multiple testing under dependency. Ann. Stat. 2001. 29: 1165-1188.
    • (2001) Ann. Stat. , vol.29 , pp. 1165-1188
    • Benjamini, Y.1    Yekutieli, D.2
  • 29
    • 0034370950 scopus 로고    scopus 로고
    • On the adaptive control of the false discovery rate in multiple testing with independent statistics
    • Benjamini, Y. and Hochberg, Y., On the adaptive control of the false discovery rate in multiple testing with independent statistics. J. Educ. Behav. Stat. 2000. 25: 60-83.
    • (2000) J. Educ. Behav. Stat , vol.25 , pp. 60-83
    • Benjamini, Y.1    Hochberg, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.