A General Efficient and Flexible Approach for Genome-Wide Association Analyses of Imputed Genotypes in Family-Based Designs

Genetic Epidemiology

Volumn 38, Issue 6, 2014, Pages 560-571

  Cobat, Aurélie ^a   Abel, Laurent ^b,c   Alcaïs, Alexandre ^b,c,d   Schurr, Erwin ^a,e  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b IMAGINE INSTITUTE   (France)

^c ROCKEFELLER UNIVERSITY   (United States)

^d The Rockefeller University ^*  (France)

^e RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

Family based association test; Genetic imputation; Genome wide association studies; Leprosy

Indexed keywords

INTERLEUKIN 23 RECEPTOR; IL23R PROTEIN, HUMAN; INTERLEUKIN RECEPTOR; RAB PROTEIN; RAB32 PROTEIN, HUMAN;

ARTICLE; CHROMOSOME 1; CHROMOSOME 6; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE TRAIT LOCUS; FAMILY STUDY; GENE; GENE DOSAGE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC LINKAGE; HETEROZYGOSITY; HUMAN; IL23R GENE; LEPROSY; PATHOGENESIS; QUANTITATIVE TRAIT LOCUS; RAB32 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC ERROR; ALLELE; BIOLOGICAL MODEL; FAMILY-BASED ASSOCIATION TEST; GENETIC IMPUTATION; GENETICS; GENOME-WIDE ASSOCIATION STUDIES; GENOTYPE; NUCLEAR FAMILY; PATHOLOGY; PHENOTYPE;

FAMILY-BASED ASSOCIATION TEST; GENETIC IMPUTATION; GENOME-WIDE ASSOCIATION STUDIES; LEPROSY;

ALLELES; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 6; DISEASE SUSCEPTIBILITY; GENETIC LINKAGE; GENETIC LOCI; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LEPROSY; MODELS, GENETIC; NUCLEAR FAMILY; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RAB GTP-BINDING PROTEINS; RECEPTORS, INTERLEUKIN;

EID: 84907811699     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.21842     Document Type: Article

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