Force spectroscopy studies on protein-ligand interactions: A single protein mechanics perspective

FEBS Letters

Volumn 588, Issue 19, 2014, Pages 3613-3620

  Hu, Xiaotang ^a   Li, Hongbin ^a,b  

^a TIANJIN UNIVERSITY   (China)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Binding assay; Force spectroscopy; Mechanical stability; Protein unfolding; Protein ligand interaction

Indexed keywords

CHAPERONIN 60; EARLY PREGNANCY FACTOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; LIGAND; PROTEIN;

BINDING AFFINITY; ENZYME KINETICS; HUMAN; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REVIEW; SIGNAL TRANSDUCTION; SINGLE MOLECULE FORCE SPECTROSCOPY; SPECTROSCOPY; THERMODYNAMICS; ATOMIC FORCE MICROSCOPY; BINDING ASSAY; CHEMISTRY; FORCE SPECTROSCOPY; MECHANICAL STABILITY; MECHANICS; METABOLISM; METHODOLOGY; OPTICAL TWEEZERS; PROTEIN BINDING; PROTEIN UNFOLDING; PROTEIN-LIGAND INTERACTION; ULTRASTRUCTURE;

BINDING ASSAY; FORCE SPECTROSCOPY; MECHANICAL STABILITY; PROTEIN UNFOLDING; PROTEIN-LIGAND INTERACTION;

HUMANS; LIGANDS; MECHANICAL PROCESSES; MICROSCOPY, ATOMIC FORCE; OPTICAL TWEEZERS; PROTEIN BINDING; PROTEIN UNFOLDING; PROTEINS; SPECTRUM ANALYSIS;

EID: 84907808419     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.04.009     Document Type: Review

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