PCB153 and p,p′-DDE disorder thyroid hormones via thyroglobulin, deiodinase 2, transthyretin, hepatic enzymes and receptors

Environmental Science and Pollution Research

Volumn 21, Issue 19, 2014, Pages 11361-11369

  Liu, Changjiang ^a,b   Ha, Mei ^c   Li, Lianbing ^a   Yang, Kedi ^b  

^a Chongqing Key Laboratory of Birth Defects and Reproductive Health   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c Chongqing There Gorges College   (China)

Author keywords

Deiodinase; Hepatic enzyme; Hormone receptor; p,p DDE; PCB153; Thyroglobulin; Thyroid hormone; Transthyretin

Indexed keywords

DDE; DOSE-RESPONSE RELATIONSHIP; ENZYME ACTIVITY; HOMEOSTASIS; HORMONE; ORGANIC POLLUTANT; PCB; RODENT;

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 2,4,5,2',4',5'-HEXACHLOROBIPHENYL; CYP3A1 PROTEIN, RAT; CYTOCHROME P450 1A1; CYTOCHROME P450 2B1; CYTOCHROME P450 3A; GLUCURONOSYLTRANSFERASE; IODIDE PEROXIDASE; LIOTHYRONINE; MESSENGER RNA; POLLUTANT; POLYCHLORINATED BIPHENYL; PREALBUMIN; THYROGLOBULIN; THYROID HORMONE RECEPTOR; THYROTROPIN; THYROXINE;

ANIMAL; BLOOD; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HYPOTHALAMUS; LIVER; MALE; METABOLISM; POLLUTANT; SPRAGUE DAWLEY RAT; TOXICITY;

ANIMALS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 CYP3A; DICHLORODIPHENYL DICHLOROETHYLENE; ENVIRONMENTAL POLLUTANTS; GLUCURONOSYLTRANSFERASE; HYPOTHALAMUS; IODIDE PEROXIDASE; LIVER; MALE; POLYCHLORINATED BIPHENYLS; PREALBUMIN; RATS, SPRAGUE-DAWLEY; RECEPTORS, THYROID HORMONE; RNA, MESSENGER; THYROGLOBULIN; THYROTROPIN; THYROXINE; TRIIODOTHYRONINE;

EID: 84907806472     PISSN: 09441344     EISSN: 16147499     Source Type: Journal    
DOI: 10.1007/s11356-014-3093-3     Document Type: Article

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