Evaluation of levetiracetam and valproic acid as low-dose monotherapies for children with typical benign childhood epilepsy with centrotemporal spikes (BECTS)

Seizure

Volumn 23, Issue 9, 2014, Pages 756-761

  Xiao, Fenglai ^a   An, Dongmei ^a   Deng, Hanyu ^a   Chen, Sihan ^a   Ren, Jiechuan ^a   Zhou, Dong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Benign childhood epilepsy with centrotemporal spikes; Levetiracetam; Low dosage; Monotherapy; Valproic acid

Indexed keywords

ETIRACETAM; VALPROIC ACID; ANTICONVULSIVE AGENT; PIRACETAM;

ARTICLE; BEHAVIOR DISORDER; BENIGN CHILDHOOD EPILEPSY; BENIGN CHILDHOOD EPILEPSY WITH CENTROTEMPORAL SPIKE; BODY MASS; CHILD; CLINICAL ASSESSMENT; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTROLLED STUDY; DIZZINESS; DROWSINESS; DRUG DOSE ESCALATION; DRUG EFFICACY; EEG ABNORMALITY; ELECTROENCEPHALOGRAM; EVENING DOSAGE; FEMALE; FOLLOW UP; HAIR LOSS; HEMATOLOGIC DISEASE; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; ONSET AGE; OUTCOME ASSESSMENT; RETROSPECTIVE STUDY; SOMNOLENCE; SPIKE; TREATMENT OUTCOME; WEIGHT GAIN; ANALOGS AND DERIVATIVES; CASE CONTROL STUDY; COHORT ANALYSIS; DRUG EFFECTS; ELECTROENCEPHALOGRAPHY; EPILEPSY, ROLANDIC; PATHOPHYSIOLOGY;

ANTICONVULSANTS; BRAIN WAVES; CASE-CONTROL STUDIES; CHILD; COHORT STUDIES; ELECTROENCEPHALOGRAPHY; EPILEPSY, ROLANDIC; FEMALE; HUMANS; MALE; PIRACETAM; VALPROIC ACID;

EID: 84907701558     PISSN: 10591311     EISSN: 15322688     Source Type: Journal    
DOI: 10.1016/j.seizure.2014.06.006     Document Type: Article

References (41)

1. R. Guerrini, and S. Pellacani Benign childhood focal epilepsies Epilepsia 53 September 2012 9 18
2. J.R. Hughes Benign epilepsy of childhood with centrotemporal spikes (BECTS): to treat or not to treat, that is the question Epilepsy Behav 19 November (3) 2010 197 203
3. P.M. Kavros, T. Clarke, L.J. Strug, J.M. Halperin, N.J. Dorta, and D.K. Pal Attention impairment in rolandic epilepsy: systematic review Epilepsia 49 September (9) 2008 1570 1580
4. F.F. Perkins, J. Breier, M.H. McManis, E. Castillo, J. Wheless, and A.L. McGregor Benign rolandic epilepsy - perhaps not so benign: use of magnetic source imaging as a predictor of outcome J Child Neurol 23 April (4) 2008 389 393
5. D.P. Sarco, K. Boyer, S.M. Lundy-Krigbaum, M. Takeoka, F. Jensen, and M. Gregas Benign rolandic epileptiform discharges are associated with mood and behavior problems Epilepsy Behav 22 October (2) 2011 298 303
6. R. Samaitienė, J. Norku¯nienė, G. Jurkevičienė, and J. Grikinienė Behavioral problems in children with benign childhood epilepsy with centrotemporal spikes treated and untreated with antiepileptic drugs Medicina (Kaunas) 48 7 2012 338 344
7. R. Guerrini Epilepsy in children Lancet 367 9509 2006 499 524
8. I. Borggraefe, M. Bonfert, T. Bast, B.A. Neubauer, K.J. Schotten, and K. Maßmann Levetiracetam vs. sulthiame in benign epilepsy with centrotemporal spikes in childhood: a double-blinded, randomized, controlled trial (German HEAD Study) Eur J Paediatr Neurol 17 September (5) 2013 507 514
9. D.S. Khurana, S.V. Kothare, I. Valencia, J.J. Melvin, and A. Legido Levetiracetam monotherapy in children with epilepsy Pediatr Neurol 36 April (4) 2007 227 230
10. T. Glauser, E. Ben-Menachem, B. Bourgeois, A. Cnaan, C. Guerreiro, and R. Kalviainen Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes Epilepsia 54 January (3) 2013 551 563
11. C.L. Corman, N.M. Leung, and A.H. Guberman Weight gain in epileptic patients during treatment with valproic acid: a retrospective study Can J Neurol Sci 24 August (3) 1997 240 244
12. U.C. Wieshmann, and G.A. Baker Self-reported feelings of anger and aggression towards others in patients on levetiracetam: data from the UK antiepileptic drug register BMJ Open 3 March (3) 2013 e002564 e002574
13. ILAE Proposal for revised classification of epilepsies and epileptic syndromes. Commission on Classification and Terminology of the International League against Epilepsy Epilepsia 30 July (4) 1989 389 399
14. P. Li, F. Yang, F. Xiong, T. Huo, Y. Tong, and S. Yang Nutritional status and risk factors of overweight and obesity for children aged 9-15 years in Chengdu, Southwest China BMC Public Health 12 August (1) 2012 1
15. C.S. Camfield, and P.R. Camfield Rolandic epilepsy has little effect on adult life 30 years later: a population-based study Neurology 82 February (13) 2014 1162 1166
16. E.A. Lukyanetz, V.M. Shkryl, and P.G. Kostyuk Selective blockade of N-type calcium channels by levetiracetam Epilepsia 43 January (1) 2002 9 18
17. B.A. Lynch, N. Lambeng, K. Nocka, P. Kensel-Hammes, S.M. Bajjalieh, and A. Matagne The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam Proc Natl Acad Sci U S A 101 June (26) 2004 9861 9866
18. S.P. Khomiakova, K.I. Mukhin, A.S. Petrukhin, and A.A. Alikhanova Diagnosis and treatment of Rolandic epilepsy Zhurnal nevrologii i psikhiatrii imeni SS Korsakova/Ministerstvo zdravookhraneniia i meditsinsko promyshlennosti Rossisko Federatsii Vserossiskoe obshchestvo nevrologov Vserossiskoe obshchestvo psikhiatrov 99 3 1999 16 21 Available from http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=10205836&retmode=ref&cmd=prlinks
19. M. Obeid, and A.W. Pong Efficacy and tolerability of high oral doses of Levetiracetam in children with epilepsy Epilepsy Res 91 September (1) 2010 101 105
20. G. Coppola, E. Franzoni, A. Verrotti, C. Garone, J. Sarajlija, and F.F. Operto Levetiracetam or oxcarbazepine as monotherapy in newly diagnosed benign epilepsy of childhood with centrotemporal spikes (BECTS): an open-label, parallel group trial Brain Dev 29 June (5) 2007 281 284
21. A. Verrotti, G. Coppola, R. Manco, G. Ciambra, P. Iannetti, and S. Grosso Levetiracetam monotherapy for children and adolescents with benign rolandic seizures Seizure 16 April (3) 2007 271 275
22. X. Zou, Z. Hong, and D. Zhou Hair loss with levetiracetam in five patients with epilepsy Seizure 23 February (2) 2014 158 160
23. J.W. Wheless, D.F. Clarke, A. Arzimanoglou, and D. Carpenter Treatment of pediatric epilepsy: European expert opinion, 2007 Epileptic Disord 9 December (4) 2007 353 412
24. A. Verrotti, C. D'Egidio, A. Mohn, G. Coppola, P. Parisi, and F. Chiarelli Antiepileptic drugs, sex hormones, and PCOS Epilepsia 52 February (2) 2011 199 211
25. T.A. Glauser, A. Cnaan, S. Shinnar, D.G. Hirtz, D. Dlugos, and D. Masur Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: initial monotherapy outcomes at 12 months Epilepsia 54 November (1) 2012 141 155
26. H. Kanemura, F. Sano, Y.-I. Maeda, K. Sugita, and M. Aihara Valproate sodium enhances body weight gain in patients with childhood epilepsy: a pathogenic mechanisms and open-label clinical trial of behavior therapy Seizure 21 September (7) 2012 496 500
27. J. Fang, S. Chen, N. Tong, L. Chen, D. An, and J. Mu Metabolic syndrome among Chinese obese patients with epilepsy on sodium valproate Seizure 21 October (8) 2012 578 582
28. K. Gordon, H. Bawden, P. Camfield, S. Mann, and P. Orlik Valproic acid treatment of learning disorder and severely epileptiform EEG without clinical seizures J Child Neurol 11 January (1) 1996 41 43
29. H. Kanemura, F. Sano, T. Tando, H. Hosaka, K. Sugita, and M. Aihara EEG improvements with antiepileptic drug treatment can show a high correlation with behavioral recovery in children with ADHD Epilepsy Behav 27 June (3) 2013 443 448
30. R.E. Bautista On the nature of interictal epileptiform discharges Clin Neurophysiol 124 November (11) 2013 2073 2074
31. S. Ebus, J. Arends, J. Hendriksen, E. van der Horst, N. de la Parra, and R. Hendriksen Cognitive effects of interictal epileptiform discharges in children Eur J Paediatr Neurol 16 November (6) 2012 697 706
32. J. Nicolai, S. Ebus, D.P. Biemans, J. Arends, J. Hendriksen, and J.S. Vles The cognitive effects of interictal epileptiform EEG discharges and short nonconvulsive epileptic seizures Epilepsia 53 June (6) 2012 1051 1059
33. U. Stephani, and G. Carlsson The spectrum from BCECTS to LKS: the rolandic EEG trait? Impact on cognition Epilepsia 47 November (s2) 2006 67 70
34. M. Wolff, N. Weiskopf, E. Serra, H. Preissl, N. Birbaumer, and I.K. Mann Benign partial epilepsy in childhood: selective cognitive deficits are related to the location of focal spikes determined by combined EEG/MEG Epilepsia 46 10 2005 1661 1667
35. J. Nicolai, I. van der Linden, J.B. Arends, S.G. van Mil, J.W. Weber, and J.S. Vles EEG characteristics related to educational impairments in children with benign childhood epilepsy with centrotemporal spikes Epilepsia 48 November (11) 2007 2093 2100
36. G. Lesca, G. Rudolf, N. Bruneau, N. Lozovaya, A. Labalme, and N. Boutry-Kryza GRIN2A mutations in acquired epileptic aphasia and related childhood focal epilepsies and encephalopathies with speech and language dysfunction Nat Genet 45 August (9) 2013 1061 1066
37. E. Tovia, H. Goldberg-Stern, B. Ben Zeev, E. Heyman, N. Watemberg, and A. Fattal-Valevski The prevalence of atypical presentations and comorbidities of benign childhood epilepsy with centrotemporal spikes Epilepsia 52 June (8) 2011 1483 1488
38. R. Massa, A. de Saint-Martin, R. Carcangiu, G. Rudolf, C. Seegmuller, and C. Kleitz EEG criteria predictive of complicated evolution in idiopathic rolandic epilepsy Neurology 57 September (6) 2001 1071 1079
39. B. Bali, L.L. Kull, L.J. Strug, T. Clarke, P.L. Murphy, and C.I. Akman Autosomal dominant inheritance of centrotemporal sharp waves in rolandic epilepsy families Epilepsia 48 December (12) 2007 2266 2272
40. V. Belcastro, C. D'Egidio, P. Striano, and A. Verrotti Metabolic and endocrine effects of valproic acid chronic treatment Epilepsy Res 107 November (1-2) 2013 1 8
41. R. Guerrini Valproate as a mainstay of therapy for pediatric epilepsy Paediatr Drugs 8 2 2006 113 129