Levetiracetam or oxcarbazepine as monotherapy in newly diagnosed benign epilepsy of childhood with centrotemporal spikes (BECTS): An open-label, parallel group trial

Brain and Development

Volumn 29, Issue 5, 2007, Pages 281-284

  Coppola, Giangennaro ^a   Franzoni, Emilio ^b   Verrotti, Alberto ^c   Garone, Caterina ^b   Sarajlija, Jasenka ^b   Operto, Francesca Felicia ^a   Pascotto, Antonio ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF CHIETI   (Italy)

Author keywords

Benign rolandic epilepsy; Children; Levetiracetam; Monotherapy; Oxcarbazepine

Indexed keywords

CARBAMAZEPINE; CLOBAZAM; ETIRACETAM; LAMOTRIGINE; OXCARBAZEPINE; TOPIRAMATE; VALPROIC ACID;

ADD ON THERAPY; ADOLESCENT; ARTICLE; BEHAVIOR DISORDER; BENIGN CHILDHOOD EPILEPSY; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DECREASED APPETITE; DROWSINESS; DRUG DOSE INCREASE; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG SUBSTITUTION; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HEADACHE; HEMATOLOGIC DISEASE; HUMAN; MALE; MONOTHERAPY; RANDOMIZED CONTROLLED TRIAL; SEDATION; SEIZURE; SIDE EFFECT;

ADOLESCENT; ANTICONVULSANTS; CARBAMAZEPINE; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPILEPSY, ROLANDIC; FEMALE; HUMANS; MALE; PILOT PROJECTS; PIRACETAM; PROSPECTIVE STUDIES; SLEEP STAGES;

EID: 33947612119     PISSN: 03877604     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.braindev.2006.09.008     Document Type: Article

References (19)

1. Panayiotopoulos C.P. Benign childhood partial seizures and related epileptic syndromes (1999), John Libbey & Company Ltd, London
2. Bourgeois B.F. Drug treatment of benign focal epilepsies of childhood. Epilepsia 41 (2000) 1057-1058
3. Doose H., Baier W.K., Ernst J.P., Tuxhorn I., and Volzke E. Benign partial epilepsy-treatment with sulthiame. Dev Med Child Neurol 30 (1988) 683-684
4. Rating D. Treatment in typical and atypical rolandic epilepsy. Epileptic Disord 2 Suppl 1 (2000) S69-S72
5. Bourgeois B.F., Brown L.W., Pellock J.M., et al. Gabapentin (Neurontin) monotherapy in children with benign childhood epilepsy with centrotemporal spikes (BECTS): a 36-week, double-blind, placebo-controlled study (abstract). Epilepsia 39 Suppl 6 (1998) S163
6. Rating D., Wolf C., and Bast T. Sulthiame as monotherapy in children with benign childhood epilepsy with centrotemporal spikes: a 6-month randomized, double-blind, placebo-controlled study. Sulthiame Study Group. Epilepsia 41 (2000) 1284-1288
7. Bello-Espinosa L.E., and Roberts S.L. Levetiracetam for benign epilepsy of childhood with centrotemporal spikes-three cases. Seizure 12 (2003) 157-159
8. Barron T.F., Hunt S.L., Hoban T.F., and Price M.L. Lamotrigine monotherapy in children. Pediatr Neurol 23 (2000) 160-163
9. Tzitiridou M., Panou T., Ramantani G., Kambas A., Spyroglou K., and Panteliadis C. Oxcarbazepine monotherapy in benign childhood epilepsy with centrotemporal spikes: a clinical and cognitive evaluation. Epilepsy Behav 7 (2005) 458-467
10. French J.A., Kanner A.M., Bautista J., Abou-Khalil B., Browne T., Harden C.L., et al. Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology; Quality Standards Subcommittee of the American Academy of Neurology; American Epilepsy Society. Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy
11. French J.A., Kanner A.M., Bautista J., Abou-Khalil B., Browne T., Harden C.L., et al. Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology; Quality Standards Subcommittee of the American Academy of Neurology; American Epilepsy Society. Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 62 (2004) 1252-1260
12. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989;30:389-99.
13. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia 1981;22:489-501.
14. Glauser T.A., Pellock J.M., Bebin E.M., Fountain N.B., Ritter F.J., Jensen C.M., et al. Efficacy and safety of levetiracetam in children with partial seizures: an open-label trial. Epilepsia 43 (2002) 518-524
15. Wheless J.W., and Ng Y.T. Levetiracetam in refractory pediatric epilepsy. J Child Neurol 17 (2002) 413-415
16. Coppola G., Mangano S., Tortorella G., Pelliccia A., Fels A., Romano A., et al. Levetiracetam during 1-year follow-up in children, adolescents, and young adults with refractory epilepsy. Epilepsy Res 59 (2004) 35-42
17. Koukkari M.W., and Guarino E.J. Retrospective study of the use of levetiracetam in childhood seizure disorders. J Child Neurol 19 (2004) 944-947
18. Grosso S., Franzoni E., Coppola G., Iannetti P., Verrotti A., Cordelli D.M., et al. Efficacy and safety of levetiracetam: An add-on trial in children with refractory epilepsy. Seizure 14 (2005) 248-253
19. Chapman K., Holland K., and Erenberg G. Seizure exacerbation associated with oxcarbazepine in idiopathic focal epilepsy of childhood. Neurology 61 (2003) 1012-1013