β3GnT8 regulates the metastatic potential of colorectal carcinoma cells by altering the glycosylation of CD147

Oncology Reports

Volumn 31, Issue 4, 2014, Pages 1795-1801

  Ni, Jianlong ^a   Jiang, Zhi ^a   Shen, Li ^a   Gao, Liping ^a   Yu, Meiyun ^a   Xu, Xu ^a   Zou, Shitao ^b   Hua, Dong ^b   Wu, Shiliang ^a  

^a SOOCHOW UNIVERSITY   (China)

^b Soochow University   (China)

Author keywords

Colorectal carcinoma cells; HG CD147; Metastasis; Polylactosamine; 3GnT8

Indexed keywords

BETA 1,3 N ACETYLGLUCOSAMINYLTRANSFERASE 8; BETA 1,6 BRANCHED POLYLACTOSAMINE; CD147 ANTIGEN; N ACETYLGLUCOSAMINYLTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL MIGRATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; WESTERN BLOTTING;

ADENOCARCINOMA; ANTIGENS, CD147; BLOTTING, WESTERN; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; FLOW CYTOMETRY; GLYCOSYLATION; HUMANS; N-ACETYLGLUCOSAMINYLTRANSFERASES; NEOPLASM INVASIVENESS; TRANSFECTION;

EID: 84907686629     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3042     Document Type: Article

References (30)

1. Demetriou M, Granovsky M, Quaggin S and Dennis JW: Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation. Nature 409: 733-739, 2001.
2. Dennis JW, Granovsky M and Warren CE: Glycoprotein glycosylation and cancer progression. Biochim Biophys Acta 1473: 21-34, 1999.
3. Saitoh O, Wang WC, Lotan R and Fukuda M: Differential glycosylation and cell surface expression of lysosomal membrane glycoproteins in sublines of a human colon cancer exhibiting distinct metastatic potentials. J Biol Chem 267: 5700-5711, 1992.
4. Figer A, Perez-Staub N, Carola E, et al: FOLFOX in patients aged between 76 and 80 years with metastatic colorectal cancer: an exploratory cohort of the OPTIMOX1 study. Cancer 110: 2666-2671, 2007.
5. Mansouri D, McMillan DC, Crighton EM and Horgan PG: Screening for colorectal cancer: what is the impact on the determinants of outcome? Crit Rev Oncol Hematol 85: 342-349, 2013.
6. Ishida H, Togayachi A, Sakai T, et al: A novel β1,3-N- acetylglucosaminyltransferase (β3Gn-T8), which synthesizes poly-N-acetyllactosamine, is dramatically upregulated in colon cancer. FEBS Lett 579: 71-78, 2005.
7. Shen L, Liu Z, Tu Y, Xu L, Sun X and Wu S: Regulation of MMP-2 expression and activity by β-1,3-N-acetylglucosaminyltransferase-8 in AGS gastric cancer cells. Mol Biol Rep 38: 1541-1550, 2011.
8. Polette M, Gilles C, Marchand V, et al: Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers. J Histochem Cytochem 45: 703-709, 1997.
9. Ellis SM, Nabeshima K and Biswas C: Monoclonal antibody preparation and purification of a tumor cell collagenase-stimulatory factor. Cancer Res 49: 3385-3391, 1989.
10. Yu XL, Jiang JL, Li L, Feng Q, Xu J and Chen ZN: The glycosylation characteristic of hepatoma-associated antigen HAb18G/CD147 in human hepatoma cells. Int J Biochem Cell Biol 38: 1939-1945, 2006.
11. Sun J and Hemler ME: Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions. Cancer Res 61: 2276-2281, 2001.
12. Carvalho FC, Soares SG, Tamarozzi MB, Rego EM and Roque-Barreira MC: The recognition of N-glycans by the lectin Artin M mediates cell death of a human myeloid leukemia cell line. PLoS One 6: e27892, 2011.
13. Naka R, Kamoda S, Ishizuka A, Kinoshita M and Kakehi K: Analysis of total N-glycans in cell membrane fractions of cancer cells using a combination of serotonin affinity chromatography and normal phase chromatography. J Proteome Res 5: 88-97, 2006.
14. Mitsui Y, Yamada K, Hara S, Kinoshita M, Hayakawa T and Kakehi K: Comparative studies on glycoproteins expressing polylactosamine-type N-glycans in cancer cells. J Pharm Biomed Anal 70: 718-726, 2012.
15. Huang C, Zhou J, Wu S, Shan Y, Teng S and Yu L: Cloning and tissue distribution of the human B3GALT7 gene, a member of the beta1,3- glycosyltransferase family. Glycoconj J 21: 267-273, 2004.
16. Yamamoto H, Swoger J, Greene S, et al: β1,6-N-acetylglucosamine- bearing N-glycans in human gliomas: implications for a role in regulating invasivity. Cancer Res 60: 134-142, 2000.
17. Fernandes B, Sagman U, Auger M, Demetrio M and Dennis JW: β1-6 branched oligosaccharides as a marker of tumor progression in human breast and colon neoplasia. Cancer Res 51: 718-723, 1991.
18. Hakomori S: Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism. Cancer Res 56: 5309-5318, 1996.
19. van den Eijnden DH, Koenderman AH and Schiphorst WE: Biosynthesis of blood group i-active polylactosaminoglycans. Partial purification and properties of an UDP-GlcNAc:N-acetyllactosaminide β1→3-N- acetylglucosaminyltransferase from Novikoff tumor cell ascites fluid. J Biol Chem 263: 12461-12471, 1988.
20. Flatmark K, Maelandsmo GM, Martinsen M, Rasmussen H and Fodstad O: Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice. Eur J Cancer 40: 1593-1598, 2004.
21. Kusakai G, Suzuki A, Ogura T, Kaminishi M and Esumi H: Strong association of ARK5 with tumor invasion and metastasis. J Exp Clin Cancer Res 23: 263-268, 2004.
22. Seko A and Yamashita K: Activation of β1,3-N- acetylglucosaminyltransferase-2 (beta3Gn-T2) by β3Gn-T8. Possible involvement of β3Gn-T8 in increasing poly-N-acetyllactosamine chains in differentiated HL-60 cells. J Biol Chem 283: 33094-33100, 2008.
23. Krishnan V, Bane SM, Kawle PD, Naresh KN and Kalraiya RD: Altered melanoma cell surface glycosylation mediates organ specific adhesion and metastasis via lectin receptors on the lung vascular endothelium. Clin Exp Metastasis 22: 11-24, 2005.
24. Demetriou M, Nabi IR, Coppolino M, Dedhar S and Dennis JW: Reduced contact-inhibition and substratum adhesion in epithelial cells expressing GlcNAc-transferase V. J Cell Biol 130: 383-392, 1995.
25. Tang W, Chang SB and Hemler ME: Links between CD147 function, glycosylation, and caveolin-1. Mol Biol Cell 15: 4043-4050, 2004.
26. Guo H, Zucker S, Gordon MK, Toole BP and Biswas C: Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells. J Biol Chem 272: 24-27, 1997.
27. Zucker S, Hymowitz M, Rollo EE, et al: Tumorigenic potential of extracellular matrix metalloproteinase inducer. Am J Pathol 158: 1921-1928, 2001.
28. Caudroy S, Polette M, Nawrocki-Raby B, et al: EMMPRIN-mediated MMP regulation in tumor and endothelial cells. Clin Exp Metastasis 19: 697-702, 2002.
29. Fan J, Wang S, Yu S, He J, Zheng W and Zhang J: N- acetylglucosaminyltransferase IVa regulates metastatic potential of mouse hepatocarcinoma cells through glycosylation of CD147. Glycoconj J 29: 323-334, 2012.
30. Huang W, Luo WJ, Zhu P, et al: Modulation of CD147-induced matrix metalloproteinase activity: role of CD147 N-glycosylation. Biochem J 449: 437-448, 2013.