-
1
-
-
48949098573
-
Safety, efficacy and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa double-blind randomised placebo-controlled trial
-
Lannfelt L, Blennow K, Zetterberg H, Batsman S, Ames D, Harrison J, et al.Safety, efficacy and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa double-blind randomised placebo-controlled trial. Lancet Neurology 2008;7:779-86.
-
(2008)
Lancet Neurology
, vol.7
, pp. 779-786
-
-
Lannfelt, L.1
Blennow, K.2
Zetterberg, H.3
Batsman, S.4
Ames, D.5
Harrison, J.6
-
2
-
-
10744224267
-
Metal-protein attenuation with iodo-chlorhroxyquin(clioquinol) targeting Aß amyloid deposition and toxicity in Alzheimer disease:a pilot phase 2 clinical trial
-
Ritchie CW, Bush AI, Mackinnon A, et al.Metal-protein attenuation with iodo-chlorhroxyquin(clioquinol) targeting Aß amyloid deposition and toxicity in Alzheimer disease:a pilot phase 2 clinical trial. Archives of Neurology 2003;60:1685-91.
-
(2003)
Archives of Neurology
, vol.60
, pp. 1685-1691
-
-
Ritchie, C.W.1
Bush, A.I.2
Mackinnon, A.3
-
4
-
-
0242381784
-
Why participate in an Alzheimer's disease clinical trial? Is it of benefit to carers and patients?
-
Mastwyk M, Macfarlane S, LoGiudice D, Sullivan KA. Why participate in an Alzheimer's disease clinical trial? Is it of benefit to carers and patients?. International Psychogeriatrics IPA 2003;15(2):149-56.
-
(2003)
International Psychogeriatrics IPA
, vol.15
, Issue.2
, pp. 149-156
-
-
Mastwyk, M.1
Macfarlane, S.2
LoGiudice, D.3
Sullivan, K.A.4
-
5
-
-
18444399243
-
Treatment of Alzheimer's disease with clioquinol
-
Regland B, Lehmann W, Abedini I, Blennow K, Jonsson M, Karlsson I, et al.Treatment of Alzheimer's disease with clioquinol. Dementia and Geriatric Cognitive Disorders 2001;12(6):408-14.
-
(2001)
Dementia and Geriatric Cognitive Disorders
, vol.12
, Issue.6
, pp. 408-414
-
-
Regland, B.1
Lehmann, W.2
Abedini, I.3
Blennow, K.4
Jonsson, M.5
Karlsson, I.6
-
6
-
-
46149107512
-
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxyquinolone analogs is associated with decreased interstitial Aß
-
Adlard PA, Cherny RA, Finkelstein DI, et al.Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxyquinolone analogs is associated with decreased interstitial Aß. Neuron 2008;59:43-55.
-
(2008)
Neuron
, vol.59
, pp. 43-55
-
-
Adlard, P.A.1
Cherny, R.A.2
Finkelstein, D.I.3
-
7
-
-
84887346660
-
Cochrane Handbook for Systematic Reviews of Interventions
-
editors. John Wiley & Sons, Ltd 5.1.0 [updated March 2011]
-
Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions 5.1.0 [updated March 2011]. The Cochrane Library. John Wiley & Sons, Ltd, 2011, issue 1:Chapter 8.
-
(2011)
The Cochrane Library
, Issue.1
-
-
Higgins, J.P.T.1
Green, S.2
-
8
-
-
0035997249
-
Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins
-
Attwood CS, Martins RN, Smith MA, Perry G. Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides 2002;23:1343-50.
-
(2002)
Peptides
, vol.23
, pp. 1343-1350
-
-
Attwood, C.S.1
Martins, R.N.2
Smith, M.A.3
Perry, G.4
-
9
-
-
0031695197
-
Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
-
Brookmeyer R, Gray S, Kawas C. Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. American Journal of Public Health 1998;88:1337-42.
-
(1998)
American Journal of Public Health
, vol.88
, pp. 1337-1342
-
-
Brookmeyer, R.1
Gray, S.2
Kawas, C.3
-
10
-
-
0027980901
-
Rapid induction of Alzheimer Aß amyloid formation by zinc
-
Bush AI, Pettingell WH, Maulthaup G, et al.Rapid induction of Alzheimer Aß amyloid formation by zinc. Science 1994;265:1464-7.
-
(1994)
Science
, vol.265
, pp. 1464-1467
-
-
Bush, A.I.1
Pettingell, W.H.2
Maulthaup, G.3
-
11
-
-
0037386086
-
The metallobiology of Alzheimer's disease
-
Bush AI. The metallobiology of Alzheimer's disease. Trends Neuroscience 2003;26:207-14.
-
(2003)
Trends Neuroscience
, vol.26
, pp. 207-214
-
-
Bush, A.I.1
-
12
-
-
0034964390
-
Treatment with copper-zinc chelator markedly and rapidly inhibits ß-amyloid accumulation in Alzheimer's disease transgenic mice
-
Cherny RA, Atwood CS, Xilianas ME, et al.Treatment with copper-zinc chelator markedly and rapidly inhibits ß-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron 2001;30:665-76.
-
(2001)
Neuron
, vol.30
, pp. 665-676
-
-
Cherny, R.A.1
Atwood, C.S.2
Xilianas, M.E.3
-
13
-
-
84870406840
-
-
3th revised. Washington, DC: American Psychiatric Association,
-
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 3th revised. Washington, DC: American Psychiatric Association, 1987.
-
(1987)
Diagnostic and Statistical Manual of Mental Disorders
-
-
-
14
-
-
84870465485
-
-
4th Edition. Washington, DC: American Psychiatric Association,
-
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th Edition. Washington, DC: American Psychiatric Association, 1994.
-
(1994)
Diagnostic and Statistical Manual of Mental Disorders
-
-
-
15
-
-
77954344206
-
PBT2 rapidly improves cognition in Alzheimer's disease: additional phase II analyses
-
Faux NG, Ritchie CW, Gunn A, et al.PBT2 rapidly improves cognition in Alzheimer's disease: additional phase II analyses. Journal of Alzheimers Disease 2010;20(2):509-16.
-
(2010)
Journal of Alzheimers Disease
, vol.20
, Issue.2
, pp. 509-516
-
-
Faux, N.G.1
Ritchie, C.W.2
Gunn, A.3
-
16
-
-
0016823810
-
Mini-mental state: a practical method for grading the cognitive state of patients for the clinician
-
Folstein MF, Folstein SE, McHugh PR. Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatry Research 1975;12:189-98.
-
(1975)
Journal of Psychiatry Research
, vol.12
, pp. 189-198
-
-
Folstein, M.F.1
Folstein, S.E.2
McHugh, P.R.3
-
17
-
-
34548639338
-
A neuropsychological test battery for use in Alzheimer disease clinical trials
-
Harrison J, Minassian SL, Jenkins L, et al.A neuropsychological test battery for use in Alzheimer disease clinical trials. Archives of Neurology 2007;64:1323-9.
-
(2007)
Archives of Neurology
, vol.64
, pp. 1323-1329
-
-
Harrison, J.1
Minassian, S.L.2
Jenkins, L.3
-
18
-
-
0028114429
-
The Clinician Interview-Based Impression (CIBI): A clinician's global change rating scale in Alzheimer's disease
-
Knopman DS, Knapp MJ, Gracon SI, Davis, CS. The Clinician Interview-Based Impression (CIBI): A clinician's global change rating scale in Alzheimer's disease. Neurology 1994;44:2315.
-
(1994)
Neurology
, vol.44
, pp. 2315
-
-
Knopman, D.S.1
Knapp, M.J.2
Gracon, S.I.3
Davis, C.S.4
-
19
-
-
80052674365
-
Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial. (Erratum)
-
Lannfelt L, Blennow K, Zetterberg H, Batsman S, Ames D, Harrison J, et al.Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial. (Erratum). Lancet Neurology 2009;8(11):981.
-
(2009)
Lancet Neurology
, vol.8
, Issue.11
, pp. 981
-
-
Lannfelt, L.1
Blennow, K.2
Zetterberg, H.3
Batsman, S.4
Ames, D.5
Harrison, J.6
-
20
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1994;34:939-44.
-
(1994)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
21
-
-
85041732428
-
Prana Completes Review of Development Programme
-
16th June 2005
-
Prana Completes Review of Development Programme. http://www.pranabio.com/downloads/Media%20Releases/2005%2016%20June%20Prana%20Completes%20Review%20of%20Development%20Plan.pdf 16th June 2005.
-
-
-
-
24
-
-
7244236841
-
A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide-the first step of a fatal cascade
-
Wirths O, Multhaup G, Bayer TA. A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide-the first step of a fatal cascade. Neurochemistry 2004;91:513-20.
-
(2004)
Neurochemistry
, vol.91
, pp. 513-520
-
-
Wirths, O.1
Multhaup, G.2
Bayer, T.A.3
-
25
-
-
0033974529
-
Changes in uptake of vitamin B12 and trace metals in brains of mice treated with clioquinol
-
Yassin MS, Ekblom J, Xilinas M, Gottfries CG, Oreland L. Changes in uptake of vitamin B12 and trace metals in brains of mice treated with clioquinol. Journal of Neurological Science 2000;173:40-4.
-
(2000)
Journal of Neurological Science
, vol.173
, pp. 40-44
-
-
Yassin, M.S.1
Ekblom, J.2
Xilinas, M.3
Gottfries, C.G.4
Oreland, L.5
|