Tandem pore domain halothane-inhibited K+channel subunits THIK1 and THIK2 assemble and form active channels

Journal of Biological Chemistry

Volumn 289, Issue 41, 2014, Pages 28202-28212

  Blin, Sandy ^a   Chatelain, Franck C ^a   Feliciangeli, Sylvain ^a   Kang, Dawon ^b   Lesage, Florian ^a   Bichet, Delphine ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b Gyeongsang National University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETICS; ENERGY TRANSFER;

ACTIVE CHANNELS; BASAL ACTIVITIES; CURRENT KINETICS; DOMINANT NEGATIVE; ENDOPLASMIC RETICULUM; INTRACELLULAR RETENTION; RESONANCE ENERGY TRANSFER; SEQUENCE HOMOLOGY;

CELL MEMBRANES;

HETERODIMER; HOMODIMER; POTASSIUM CHANNEL; TANDEM PORE DOMAIN HALOTHANE INHIBITED POTASSIUM CHANNEL 1; TANDEM PORE DOMAIN HALOTHANE INHIBITED POTASSIUM CHANNEL 2; UNCLASSIFIED DRUG; CHLORIDE; KCNK13 PROTEIN, HUMAN; POTASSIUM; RECOMBINANT PROTEIN; TANDEM PORE DOMAIN POTASSIUM CHANNEL; THIK-2 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CHANNEL GATING; CONTROLLED STUDY; DIMERIZATION; ELECTROPHYSIOLOGY; ENDOPLASMIC RETICULUM; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; MUTATION; NONHUMAN; POTASSIUM CURRENT; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DOG; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; ION TRANSPORT; KINETICS; MDCK CELL LINE; MEMBRANE POTENTIAL; METABOLISM; MOLECULAR GENETICS; OOCYTE; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; CHLORIDES; DOGS; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; ION TRANSPORT; KINETICS; MADIN DARBY CANINE KIDNEY CELLS; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

EID: 84907638175     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.600437     Document Type: Article

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