Sclerostin deficiency is linked to altered bone composition

Journal of Bone and Mineral Research

Volumn 29, Issue 10, 2014, Pages 2144-2151

  Hassler, Norbert ^a   Roschger, Andreas ^a   Gamsjaeger, Sonja ^a   Kramer, Ina ^b   Lueger, Sonja ^a   Van Lierop, Antoon ^c   Roschger, Paul ^a   Klaushofer, Klaus ^a   Paschalis, Eleftherios P ^a   Kneissel, Michaela ^b   Papapoulos, Socrates ^c  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^b NOVARTIS PHARMA AG   (Switzerland)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Bone; Bone mineral density distribution; Mineral maturity crystallinity; Mineralization kinetics; Proteoglycans; Quantitative backscattered electron imaging; Raman microspectroscopy; Sclerostin deficiency

Indexed keywords

PROTEOGLYCAN; SCLEROSTIN; BONE MORPHOGENETIC PROTEIN; GENETIC MARKER; GLYCOPROTEIN; SOST PROTEIN, HUMAN; SOST PROTEIN, MOUSE;

ADOLESCENT; ADULT; ANIMAL TISSUE; ARTICLE; BONE MINERALIZATION; BONE STRENGTH; BONE TISSUE; CHILD; CONTROLLED STUDY; CORTICAL BONE; HUMAN; HUMAN TISSUE; MINERALIZATION; MOUSE; NONHUMAN; OSTEOSCLEROSIS; PROTEIN DEFICIENCY; SCLEROSTIN DEFICIENCY; ANALYSIS OF VARIANCE; ANIMAL; BONE DENSITY; DEFICIENCY; ELECTRON; FLUORESCENCE MICROSCOPY; GENETIC MARKER; HYPEROSTOSIS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PRESCHOOL CHILD; RAMAN SPECTROMETRY; SYNDACTYLY; YOUNG ADULT;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; ANIMALS; BONE DENSITY; BONE MORPHOGENETIC PROTEINS; CALCIFICATION, PHYSIOLOGIC; CHILD; CHILD, PRESCHOOL; ELECTRONS; GENETIC MARKERS; GLYCOPROTEINS; HUMANS; HYPEROSTOSIS; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; SPECTRUM ANALYSIS, RAMAN; SYNDACTYLY; YOUNG ADULT;

EID: 84907626894     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2259     Document Type: Article

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