Validation of statistical imputation of allele-level multilocus phased genotypes from ambiguous HLA assignments

Tissue Antigens

Volumn 84, Issue 3, 2014, Pages 285-292

  Madbouly, A ^a   Gragert, L ^a   Freeman, J ^a   Leahy, N ^a   Gourraud, P A ^b   Hollenbach, J A ^c   Kamoun, M ^d   Fernandez Vina, M ^e   Maiers, M ^a  

^a NATIONAL MARROW DONOR PROGRAM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^d HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^e STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Expectation maximization; Human leukocyte antigen; Imputation; Maximum likelihood; Typing ambiguity; Typing resolution

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; HLA DRB1 ANTIGEN; HLA ANTIGEN;

ALLELE; AMBIGUITY; ARTICLE; COMPUTER MODEL; ENTROPY; ETHNICITY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ALGORITHM; GENOTYPE; HAPLOTYPE; HLA MATCHING; HLA SYSTEM; HUMAN; IMMUNOGENETICS; POPULATION GENETICS; PREDICTION; PRIORITY JOURNAL; RACE; REGISTER; SEROLOGY; SIMULATION; STATISTICAL ANALYSIS; VALIDATION STUDY; BIOLOGICAL MODEL; COMPUTER SIMULATION; DONOR; ETHNIC GROUP; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY TEST; PROCEDURES; STATISTICS AND NUMERICAL DATA; UNITED STATES;

ALLELES; COMPUTER SIMULATION; ETHNIC GROUPS; GENE FREQUENCY; GENETIC LOCI; GENOTYPE; HAPLOTYPES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; REGISTRIES; TISSUE DONORS; UNITED STATES;

EID: 84907597807     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/tan.12390     Document Type: Article

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