State of the Art Review: HLA Matching and Outcome of Unrelated Donor Umbilical Cord Blood Transplants

Biology of Blood and Marrow Transplantation

Volumn 14, Issue 1, 2008, Pages 1-6

  Kamani, Naynesh ^a   Spellman, Stephen ^b   Hurley, Carolyn Katovich ^c   Barker, Juliet N ^d   Smith, Franklin O ^e   Oudshoorn, Machteld ^f   Bray, Robert ^g   Smith, Anajane ^h   Williams, Thomas M ⁱ   Logan, Brent ^j   Eapen, Mary ^j   Anasetti, Claudio ^k   Setterholm, Michelle ^b   Confer, Dennis L ^b  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^b NATIONAL MARROW DONOR PROGRAM   (United States)

^c GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^f Europdonor Foundation   (Netherlands)

^g EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h SEATTLE CANCER CARE ALLIANCE   (United States)

ⁱ UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^j MEDICAL COLLEGE OF WISCONSIN   (United States)

^k H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; HLA DQB1 ANTIGEN;

ALLELE; CRYOPRESERVATION; EDITORIAL; ENGRAFTMENT; GRAFT RECIPIENT; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA MATCHING; HLA TYPING; HUMAN; OUTCOME ASSESSMENT; PRACTICE GUIDELINE; SURVIVAL; UMBILICAL CORD BLOOD;

CORD BLOOD STEM CELL TRANSPLANTATION; GENOTYPE; GRAFT SURVIVAL; GRAFT VS HOST DISEASE; HISTOCOMPATIBILITY TESTING; HUMANS; SENSITIVITY AND SPECIFICITY; TRANSPLANTATION, HOMOLOGOUS;

EID: 37349091178     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2007.11.003     Document Type: Editorial

References (28)

1. Kurtzberg J., Laughlin M., Graham M.L., et al. Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N Engl J Med 335 (1996) 157-166
2. Eapen M., Rubinstein P., Zhang M.J., et al. Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study. Lancet 369 (2007) 1947-1954
3. Rocha V., Cornish J., Sievers E.L., et al. Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia. Blood 97 (2001) 2962-2971
4. Laughlin M.J., Barker J., Bambach B., et al. Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors. N Engl J Med 344 (2001) 1815-1822
5. Laughlin M.J., Eapen M., Rubinstein P., et al. Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia. N Engl J Med 351 (2004) 2265-2275
6. Barker J.N., Davies S.M., DeFor T., Ramsay N.K., Weisdorf D.J., and Wagner J.E. Survival after transplantation of unrelated donor umbilical cord blood is comparable to that of human leukocyte antigen-matched unrelated donor bone marrow: results of a matched-pair analysis. Blood 97 (2001) 2957-2961
7. Gluckman E., and Rocha V. Donor selection for unrelated cord blood transplants. Curr Opin Immunol 18 (2006) 565-570
8. Hurley C., Baxter-Lowe L.A., Davies S., et al. National Marrow Donor Program HLA matching guidelines for unrelated marrow transplants. Biol Blood Marrow Transplant 9 (2003) 610-615
9. Petersdorf E.W., Longton G.M., Anasetti C., et al. The significance of HLA-DRB1 matching on clinical outcome after HLA-A, B, DR identical unrelated donor marrow transplantation. Blood 86 (1995) 1606-1613
10. Flomenberg N., Baxter-Lowe L.A., Confer D., et al. Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. Blood 104 (2004) 1923-1930
11. Morishima Y., Sasazuki T., Inoki H., et al. The clinical significance of human leukocyte antigen (HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched unrelated donors. Blood 99 (2002) 4200-4206
12. Petersdorf E.W., Anasetti C., Martin P.J., et al. Limits of HLA mismatching in unrelated hematopoietic cell transplantation. Blood 104 (2004) 2976-2980
13. Lee SJ, Klein J, Haagenson M, et al. The contribution of high resolution donor-recipient HLA matching to the success of unrelated donor marrow transplantation. Prepublished online September 4, 2007; doi 10.1182/blood-2007-06-097386.
14. Kernan N.A., Carter S.L., Wagner J.E., et al. Umbilical cord blood transplantation in pediatric patients: results of the prospective, multi-institutional cord blood transplantation study (COBLT). Tandem BMT Meetings Abstract (2006)
15. Kogler G., Enczmann J., Rocha V., Gluckman E., and Wernet P. High-resolution HLA typing by sequencing for HLA-A, -B, -C, -DR, -DQ in 122 unrelated cord blood/patient pair transplants hardly improves long-term clinical outcome. Bone Marrow Transplant 36 (2005) 1033-1041
16. Ohnuma K., Isoyama K., Ikuta K., et al. The influence of HLA genotyping compatibility on clinical outcome after cord blood transplantation from unrelated donors. J Hematother Stem Cell Res 9 (2000) 541-550
17. Cornetta K., Laughlin M., Carter S., et al. Umbilical cord blood transplantation in adults: results of the prospective Cord Blood Transplantation (COBLT). Biol Blood Marrow Transplant 11 (2005) 149-160
18. Kurtzberg J, Carter SL, Wagner JE, et al. Results of the Cord Blood Transplantation Study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with leukemia. Submitted.
19. Petersdorf E.W., Longton G.M., Anasetti C., et al. Definition of HLA-DQ as a transplantation antigen. Proc Natl Acad Sci USA 93 (1996) 15358-15363
20. Hurley C.K., Fernandez-Vina M., Hildebrand W.H., et al. A high degree of HLA diversity arises from limited allelic diversity: analysis of 1775 unrelated bone marrow transplant donor-recipient pairs. Hum Immunol 68 (2007) 30-40
21. Rocha V., Labopin M., Sanz G., et al. Acute Leukemia Working Party of European Blood and Marrow Transplant Group; Eurocord-Netcord Registry. Transplants of umbilical-cord blood or bone marrow from unrelated donors in adults with acute leukemia. N Engl J Med 351 (2004) 2276-2285
22. Rubinstein P., Carrier C., Scaradavou A., et al. Outcomes among 562 recipients of placental-blood transplants from unrelated donors. N Engl J Med 339 (1998) 1565-1577
23. Gluckman E., Rocha V., Boyer-Chammard A., et al. Outcome of cord-blood transplantation from related and unrelated donors. Eurocord Transplant Group and the European Blood and Marrow Transplantation Group. N Engl J Med 337 (1997) 373-381
24. Wagner J.E., Rosenthal J., Sweetman R., et al. Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: analysis of engraftment and acute graft-versus-host disease. Blood 88 (1996) 795-802
25. Wagner J.E., Barker J.N., DeFor T.E., et al. Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival. Blood 100 (2002) 1611-1618
26. Migliaccio A.R., Adamson J.W., Stevens C.E., Dobrila N.L., Carrier C.M., and Rubinstein P. Cell dose and speed of engraftment in placental/umbilical cord blood transplantation: graft progenitor cell content is a better predictor than nucleated cell quantity. Blood 96 (2000) 2717-2722
27. Gluckman E., Rocha V., Arcese W., et al. Factors associated with outcomes of unrelated cord blood transplant: guidelines for donor choice. Exp Hematol 32 (2004) 397-407
28. Gibbons R. Analysis of the NYBC, NMDP and NHLBI Cord Blood Data. IOM Report. Cord blood: establishing a National Hematopoietic Stem Cell Bank Program. IOM (2005) 265-273