Angiopoietin-like 7, a novel pro-angiogenetic factor over-expressed in cancer

Angiogenesis

Volumn 17, Issue 4, 2014, Pages 881-896

  Parri, Matteo ^a   Pietrovito, Laura ^b   Grandi, Alberto ^a   Campagnoli, Susanna ^a   De Camilli, Elisa ^c   Bianchini, Francesca ^d   Marchiò, Serena ^e,f   Bussolino, Federico ^e,f   Jin, Boquan ^g   Sarmientos, Paolo ^a   Grandi, Guido ^h   Viale, Giuseppe ^c,i   Pileri, Piero ^a   Chiarugi, Paola ^b   Grifantini, Renata ^a  

^a Externautics SpA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^d UNIVERSITY OF FLORENCE   (Italy)

^e UNIVERSITY OF TURIN   (Italy)

^f CANDIOLO CANCER INSTITUTE   (Italy)

^g FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^h NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

ⁱ UNIVERSITY OF MILAN   (Italy)

Author keywords

Angiogenesis; Angiopoietin like; ANGPTL7; Cancer; Tissue microarray

Indexed keywords

ANGIOPOIETIN; ANGIOPOIETIN LIKE 7; PROTEIN ANGPTL7; UNCLASSIFIED DRUG; ANGPTL7 PROTEIN, HUMAN; CULTURE MEDIUM;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER GROWTH; CELL DIFFERENTIATION; CELL INVASION; CELL MOTILITY; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; MALE; MELANOMA CELL LINE; MOUSE; NEOPLASM; NONHUMAN; OVARY CANCER; PROGENITOR CELL LINE; PROSTATE CANCER; PROTEIN EXPRESSION; REGULATORY MECHANISM; TISSUE MICROARRAY; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; VASCULARIZATION; CELL HYPOXIA; CELL MOTION; CHEMISTRY; COLORECTAL TUMOR; CULTURE MEDIUM; CYTOLOGY; DNA MICROARRAY; ENDOCRINE SYSTEM; ENDOTHELIUM CELL; EXOSOME; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); TUMOR CELL LINE; TUMOR INVASION;

ANGIOPOIETINS; CELL DIFFERENTIATION; CELL HYPOXIA; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CULTURE MEDIA, CONDITIONED; ENDOCRINE SYSTEM; ENDOTHELIAL CELLS; EXOSOMES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASM INVASIVENESS; NEOVASCULARIZATION, PATHOLOGIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; UP-REGULATION;

EID: 84907592713     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-014-9435-4     Document Type: Article

References (41)

1. Santulli G (2014) Angiopoietin-like proteins: a comprehensive look. Front Endocrinol (Lausanne) 5:4
2. Oike Y, Ito Y, Maekawa H, Morisada T, Kubota Y, Akao M, Urano T, Yasunaga K, Suda T (2004) Angiopoietin-related growth factor (AGF) promotes angiogenesis. Blood 103:3760-3765
3. Morisada T, Kubota Y, Urano T, Suda T, Oike Y (2006) Angiopoietins and angiopoietin-like proteins in angiogenesis. Endothelium 13:71-79
4. Oike Y, Yasunaga K, Suda T (2004) Angiopoietin-related/angiopoietin-like proteins regulate angiogenesis. Int J Hematol 80:21-28
5. Hato T, Tabata M, Oike Y (2008) The role of angiopoietin-like proteins in angiogenesis and metabolism. Trends Cardiovasc Med 18:6-14
6. Zhu P, Goh YY, Chin HF, Kersten S, Tan NS (2012) Angiopoietin-like 4: a decade of research. Biosci Rep 32:211-219
7. Zhang CC, Kaba M, Ge G, Xie K, Tong W, Hug C, Lodish HF (2006) Emerging roles of lipasin as a critical lipid regulator. Nat Med 12:240-245
8. Kadomatsu T, Tabata M, Oike Y (2011) Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases. FEBS J 278:559-564
9. Oike Y, Akao M, Yasunaga K, Yamauchi T, Morisada T, Ito Y, Urano T, Kimura Y, Kubota Y, Maekawa H, Miyamoto T, Miyata K, Matsumoto S, Sakai J, Nakagata N, Takeya M, Koseki H, Ogawa Y, Kadowaki T, Suda T (2005) Angiopoietin-related growth factor antagonizes obesity and insulin resistance. Nat Med 11:400-408
10. Oike Y, Tabata M (2009) Angiopoietin-like proteins-potential therapeutic targets for metabolic syndrome and cardiovascular disease. Circ J 73:2192-2197
11. Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, Viale A, Olshen AB, Gerald WL, Massague J (2005) Genes that mediate breast cancer metastasis to lung. Nature 436:518-524
12. Endo M, Nakano M, Kadomatsu T, Fukuhara S, Kuroda H, Mikami S, Hato T, Aoi J, Horiguchi H, Miyata K, Odagiri H, Masuda T, Harada M, Horio H, Hishima T, Nomori H, Ito T, Yamamoto Y, Minami T, Okada S, Takahashi T, Mochizuki N, Iwase H, Oike Y (2012) Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis. Cancer Res 72:1784-1794
13. Aoi J, Endo M, Kadomatsu T, Miyata K, Nakano M, Horiguchi H, Ogata A, Odagiri H, Yano M, Araki K, Jinnin M, Ito T, Hirakawa S, Ihn H, Oike Y (2011) Angiopoietin-like protein 2 is an important facilitator of inflammatory carcinogenesis and metastasis. Cancer Res 71:7502-7512
14. Marchio S, Soster M, Cardaci S, Muratore A, Bartolini A, Barone V, Ribero D, Monti M, Bovino P, Sun J, Giavazzi R, Asioli S, Cassoni P, Capussotti L, Pucci P, Bugatti A, Rusnati M, Pasqualini R, Arap W, Bussolino F (2012) A complex of alpha6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6. EMBO Mol Med 4:1156-1175
15. Peek R, van Gelderen BE, Bruinenberg M, Kijlstra A (1998) Molecular cloning of a new angiopoietinlike factor from the human cornea. Invest Ophthalmol Vis Sci 39:1782-1788
16. Peek R, Kammerer RA, Frank S, Otte-Holler I, Westphal JR (2002) The angiopoietin-like factor cornea-derived transcript 6 is a putative morphogen for human cornea. J Biol Chem 277:686-693
17. Kuchtey J, Kallberg ME, Gelatt KN, Rinkoski T, Komaromy AM, Kuchtey RW (2008) Angiopoietin-like 7 secretion is induced by glaucoma stimuli and its concentration is elevated in glaucomatous aqueous humor. Invest Ophthalmol Vis Sci 49:3438-3448
18. Nehme A, Lobenhofer EK, Stamer WD, Edelman JL (2009) Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells. BMC Med Genomics 2:58
19. Stevens AL, Wishnok JS, Chai DH, Grodzinsky AJ, Tannenbaum SR (2008) A sodium dodecyl sulfate-polyacrylamide gel electrophoresis-liquid chromatography tandem mass spectrometry analysis of bovine cartilage tissue response to mechanical compression injury and the inflammatory cytokines tumor necrosis factor alpha and interleukin-1beta. Arthritis Rheum 58:489-500
20. Bouis D, Hospers GA, Meijer C, Dam W, Peek R, Mulder NH (2003) Effects of the CDT6/ANGX gene on tumour growth in immune competent mice. In Vivo 17:157-161
21. Bouis DR, Dam WA, Meijer C, Mulder NH, Hospers GA (2007) CDT6-expression can alter tumor sensitivity to chemotherapy. Anticancer Res 27:2325-2329
22. Grifantini R, Pagani M, Pierleoni A, Grandi A, Parri M, Campagnoli S, Pileri P, Cattaneo D, Canidio E, Pontillo A, De CE, Bresciani A, Marinoni F, Pedrazzoli E, Nogarotto R, Abrignani S, Viale G, Sarmientos P, Grandi G (2011) A novel polyclonal antibody library for expression profiling of poorly characterized, membrane and secreted human proteins. J Proteomics 75:532-547
23. Margheri F, Chilla A, Laurenzana A, Serrati S, Mazzanti B, Saccardi R, Santosuosso M, Danza G, Sturli N, Rosati F, Magnelli L, Papucci L, Calorini L, Bianchini F, Del RM, Fibbi G (2011) Endothelial progenitor cell-dependent angiogenesis requires localization of the full-length form of uPAR in caveolae. Blood 118:3743-3755
24. Serrati S, Margheri F, Pucci M, Cantelmo AR, Cammarota R, Dotor J, Borras-Cuesta F, Fibbi G, Albini A, Del RM (2009) TGFbeta1 antagonistic peptides inhibit TGFbeta1-dependent angiogenesis. Biochem Pharmacol 77:813-825
25. Raposo G, Nijman HW, Stoorvogel W, Liejendekker R, Harding CV, Melief CJ, Geuze HJ (1996) B lymphocytes secrete antigen-presenting vesicles. J Exp Med 183:1161-1172
26. Lundberg M, Thorsen SB, Assarsson E, Villablanca A, Tran B, Gee N, Knowles M, Nielsen BS, Gonzalez CE, Martin R, Nilsson O, Fermer C, Schlingemann J, Christensen IJ, Nielsen HJ, Ekstrom B, Andersson C, Gustafsson M, Brunner N, Stenvang J, Fredriksson S (2011) Multiplexed homogeneous proximity ligation assays for high-throughput protein biomarker research in serological material. Mol Cell Proteomics 10:M110
27. Wu Y, Al-Ameen MA, Ghosh G (2014) Integrated effects of matrix mechanics and vascular endothelial growth factor (VEGF) on capillary sprouting. Ann Biomed Eng 42:1024-1036
28. Yang YH, Wang Y, Lam KS, Yau MH, Cheng KK, Zhang J, Zhu W, Wu D, Xu A (2008) Suppression of the Raf/MEK/ERK signaling cascade and inhibition of angiogenesis by the carboxyl terminus of angiopoietin-like protein 4. Arterioscler Thromb Vasc Biol 28:835-840
29. Potente M, Gerhardt H, Carmeliet P (2011) Basic and therapeutic aspects of angiogenesis. Cell 146:873-887
30. Carmeliet P, Jain RK (2011) Molecular mechanisms and clinical applications of angiogenesis. Nature 473:298-307
31. Liu H, Paradis H, Gendron RL, Choi DW, Chapon P, Tseng S, Kao C, Kao W (2001) ANGX/CDT6 a novel fibrinogen/angiopoietin-like factor that enhances angiogenesis in vivo. Invest Ophthalmol Vis Sci 42:S478
32. Asahara T, Kawamoto A, Masuda H (2011) Concise review: circulating endothelial progenitor cells for vascular medicine. Stem Cells 29:1650-1655
33. Timmermans F, Plum J, Yoder MC, Ingram DA, Vandekerckhove B, Case J (2009) Endothelial progenitor cells: identity defined? J Cell Mol Med 13:87-102
34. Sasaki H, Suzuki A, Shitara M, Hikosaka Y, Okuda K, Moriyama S, Yano M, Fujii Y (2012) Angiopoietin-like protein ANGPTL2 gene expression is correlated with lymph node metastasis in lung cancer. Oncol Lett 4:1325-1328
35. Benita Y, Kikuchi H, Smith AD, Zhang MQ, Chung DC, Xavier RJ (2009) An integrative genomics approach identifies hypoxia inducible factor-1 (HIF-1)-target genes that form the core response to hypoxia. Nucleic Acids Res 37:4587-4602
36. Katoh Y, Katoh M (2006) Comparative integromics on angiopoietin family members. Int J Mol Med 17:1145-1149
37. Reis M, Liebner S (2013) Wnt signaling in the vasculature. Exp Cell Res 319:1317-1323
38. Liu JJ, Wilson SE (2001) Characterization of human and mouse angiopoietin-like factor CDT6 promoters. Invest Ophthalmol Vis Sci 42:2776-2783
39. Santulli G, Ciccarelli M, Palumbo G, Campanile A, Galasso G, Ziaco B, Altobelli GG, Cimini V, Piscione F, D'Andrea LD, Pedone C, Trimarco B, Iaccarino G (2009) In vivo properties of the proangiogenic peptide QK. J Transl Med 7:41
40. Santulli G, Basilicata MF, De SM, Del GC, Anastasio A, Sorriento D, Saviano M, Del GA, Trimarco B, Pedone C, Zaccaro L, Iaccarino G (2011) Evaluation of the anti-angiogenic properties of the new selective alphaVbeta3 integrin antagonist RGDechiHCit. J Transl Med 9:7
41. Santulli G, Cipolletta E, Sorriento D, Del GC, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G (2012) CaMK4 gene deletion induces hypertension. J Am Heart Assoc 1:e001081