A process economic assessment of hydrocarbon biofuels production using chemoautotrophic organisms

Bioresource Technology

Volumn 172, Issue , 2014, Pages 201-211

  Khan, Nymul E ^a   Myers, John A ^a,b   Tuerk, Amalie L ^a,c   Curtis, Wayne R ^a  

^a The Pennsylvania State University   (United States)

^b Motiva Enterprises LLC   (United States)

^c UNIVERSITY OF DELAWARE   (United States)

Author keywords

Bioreactor kLa cost review; Carbon fixation; Electrofuels; Ralstonia eutropha; Rhodobacter capsulatus

Indexed keywords

BACTERIA; BIOREACTORS; C (PROGRAMMING LANGUAGE); CARBON; CARBON DIOXIDE; CRUDE OIL; ECONOMIC ANALYSIS; FUELS; HYDROCARBONS; MASS TRANSFER; OPERATING COSTS;

CAPITAL AND OPERATING COSTS; CARBON FIXATION; ELECTROFUELS; GAS-LIQUID MASS-TRANSFER COEFFICIENT; LEVELIZED COST OF ELECTRICITIES; MAINTENANCE REQUIREMENT; RALSTONIA EUTROPHA; RHODOBACTER CAPSULATUS;

COST BENEFIT ANALYSIS;

BIOFUEL; BOTRYOCOCCENE; CARBON DIOXIDE; CHEMICAL COMPOUND; HYDROCARBON; HYDROGEN; OXYGEN; UNCLASSIFIED DRUG; TRITERPENE;

BACTERIUM; BIOENGINEERING; BIOFUEL; BIOREACTOR; CARBON FIXATION; CHEMOAUTOTROPHY; COST ANALYSIS; HYDROCARBON;

ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BIOFUEL PRODUCTION; BIOREACTOR; CELL GROWTH; CHEMICAL COMPOSITION; CHEMOAUTOTROPHY; COST BENEFIT ANALYSIS; CUPRIAVIDUS NECATOR; ECONOMIC ASPECT; ELECTRICITY; GAS; HOST SELECTION; LIQUID; MASS; MEAN RESIDENCE TIME; NONHUMAN; POPULUS; PROCESS MODEL; PRODUCTIVITY; PROGRAM FEASIBILITY; RHODOBACTER CAPSULATUS; SENSITIVITY ANALYSIS; SIMULATION; ECONOMICS; METABOLISM; STATISTICAL MODEL;

CUPRIAVIDUS NECATOR; RHODOBACTER CAPSULATUS;

BIOFUELS; BIOREACTORS; CHEMOAUTOTROPHIC GROWTH; CUPRIAVIDUS NECATOR; MODELS, ECONOMIC; RHODOBACTER CAPSULATUS; TRITERPENES;

EID: 84907569561     PISSN: 09608524     EISSN: 18732976     Source Type: Journal    
DOI: 10.1016/j.biortech.2014.08.118     Document Type: Article

References (44)

1. Alper H., Miyaoku K., Stephanopoulos G. Construction of lycopene-overproducing 2 strains by combining systematic and combinatorial gene knockout targets. Nat. Biotechnol. 2005, 23:612-616.
2. Bartels J.R., Pate M.B., Olson N.K. An economic survey of hydrogen production from conventional and alternative energy sources. Int. J. Hydrogen Energy 2010, 35:8371-8384.
3. Beekwilder J., van Houwelingen A., Cankar K., van Dijk A.D.J., de Jong R.M., Stoopen G., Bouwmeester H., Achkar J., Sonke T., Bosch D. Valencene synthase from the heartwood of Nootka cypress (Callitropsis nootkatensis) for biotechnological production of valencene. Plant Biotechnol. J. 2014, 12:174-182.
4. Bredwell M.D., Worden R.M. Mass-transfer properties of microbubbles. 1. Experimental studies. Biotechnol. Prog. 1998, 14:31-38.
5. Cosby G.M., Gay D.W. Clean water testing of innovative surface aerators promises significant savings for chattanooga's moccasin bend WWTP. Proc. Water Environ. Fed. 2003, 272-281.
6. De Castro C., Carpintero Ó., Frechoso F., Mediavilla M., de Miguel L.J. A top-down approach to assess physical and ecological limits of biofuels. Energy 2014, 64:506-512.
7. Derenne S., Largeau C., Hetényi M., Brukner-Wein A., Connan J., Lugardon B. Chemical structure of the organic matter in a Pliocene maar-type shale: implicated Botryococcus race strains and formation pathways. Geochim. Cosmochim. Acta 1997, 61:1879-1889.
8. Farmer W.R., Liao J.C. Precursor balancing for metabolic engineering of lycopene production in Escherichia coli. Biotechnol. Prog. 2001, 17:57-61.
9. Goto S., Smith J.M. Trickle-bed reactor performance. Part I. Holdup and mass transfer effects. AIChE J. 1975, 21:706-713.
10. Gruenspecht, H., 2012. Annual Energy Outlook 2012, Report#: DOE/EIA-0383. URL <>. http://www.eia.gov/forecasts/aeo/pdf/0383%282012%29.pdf.
11. Hammerschlag R. Ethanol's energy return on investment: a survey of the literature 1990-present. Environ. Sci. Technol. 2006, 40:1744-1750.
12. Hensirisak P., Parasukulsatid P., Agblevor F.A, Cundiff J.S., Velander W.H. Scale-up of microbubble dispersion generator for aerobic fermentation. Appl. Biochem. Biotechnol. 2002, 101:211-227.
13. Hildebrand A., Schlacta T., Warmack R., Kasuga T., Fan Z. Engineering Escherichia coli for improved ethanol production from gluconate. J. Biotechnol. 2013, 168:101-106.
14. Hillen L.W., Pollard G., Wake L.V., White N. Hydrocracking of the oils of Botryococcus braunii to transport fuels. Biotechnol. Bioeng. 1982, 24:193-205.
15. Hoekema S., Douma R.D.R.D., Janssen M., Tramper J., Wijffels R.H. Controlling light-use by Rhodobacter capsulatus continuous cultures in a flat-panel photobioreactor. Biotechnol. Bioeng. 2006, 95:613-626.
16. Hsiao T., Bacani F., Carvalho E., Curtis W.R. Development of a low capital investment reactor system: application for plant cell suspension culture. Biotechnol. Prog. 1999, 15:114-122.
17. Hunter, C., Daldal, F., Thurnauer, M.C., Beatty, J.T. (Eds.), 2009. Advances in Photosynthesis and Respiration, vol 28. In: The Purple Phototrophic Bacteria. Springer, Dordrecht, The Netherlands.
18. IRENA, 2012. Renewable Power Generation Costs in 2012: an Overview. URL <>. http://costing.irena.org/media/2769/Overview_Renewable-Power-Generation-Costs-in-2012.pdf.
19. Ishizaki A., Tanaka K. Batch culture of Alcaligenes eutrophus ATCC 17697T using recycled gas closed circuit culture system. J. Ferment. Bioeng. 1990, 69:170-174.
20. Khan, N.E., Myers, J.A., Johnson, R., Rajangam, A., Nybo, E., Chappell, J., Curtis, W., 2013. Progress and Economic Considerations for the Biological Production of Triterpene Biofuels From Gases. In: AICHE 2013 Annual Meeting. Pittsburgh, PA.
21. Khatri W., Hendrix R., Niehaus T., Chappell J., Curtis W.R. Hydrocarbon production in high density Botryococcus braunii race B continuous culture. Biotechnol. Bioeng. 2014, 111:493-503.
22. Kim S.-W., Kim J.-B., Jung W.-H., Kim J.-H., Jung J.-K. Over-production of beta-carotene from metabolically engineered Escherichia coli. Biotechnol. Lett. 2006, 28:897-904.
23. Larachi F., Laurent A., Midoux N., Wild G. Experimental study of a trickle-bed reactor operating at high pressure: two-phase pressure drop and liquid saturation. Chem. Eng. Sci. 1991, 46:1233-1246.
24. Lewis W.P., Gay D.W. New surface aerators reduced Yuba City's oxygen dissolution power draw by 33%. Proc. Water Environ. Fed. 2003, 392-401.
25. Linek V., Vacek V., Beneš P. A critical review and experimental verification of the correct use of the dynamic method for the determination of oxygen transfer in aerated agitated vessels to water, electrolyte solutions and viscous liquids. Chem. Eng. J. 1987, 34:11-34.
26. Mccarty P.L. Energetics and bacterial growth. Organic Compounds in Aquatic Environment 1971, 495-531. Marcel Dekker Inc., New York, NY. S.J. Faust, J.V. Hunter (Eds.).
27. McCarty P.L. Thermodynamic electron equivalents model for bacterial yield prediction: modifications and comparative evaluations. Biotechnol. Bioeng. 2007, 97:377-388.
28. Metz B., Davidson O., de Coninck H., Loos M., Meyer L. IPCC Special Report on Carbon Dioxide Capture and Storage 2005, Cambridge University Press, New York, NY, ISBN: 13978-0-521-86643-9.
29. Metzger P., Largeau C. Botryococcus braunii: a rich source for hydrocarbons and related ether lipids. Appl. Microbiol. Biotechnol. 2005, 66:486-496.
30. Myers, J., 2013. The scaled-up process design and economic analysis of an electorfuels platform for producing botryococcene as an alternative transportation fuel (thesis). The Pennsylvania State University. URL < >. https://honors.libraries.psu.edu/paper/17879/.
31. Nebraska, 2014. Ethanol facilities capacity by state and plant [WWW Document]. URL <>. http://www.neo.ne.gov/statshtml/122.htm.
32. Ohta K., Beall D., Mejia J., Shanmugam K., Ingram L. Genetic improvement of Escherichia coli for ethanol production: chromosomal integration of Zymomonas mobilis genes encoding pyruvate decarboxylase and alcohol. Appl. Environ. Microbiol. 1991, 57:893-900.
33. Okada S., Devarenne T., Murakami M., Abe H., Chappell J. Characterization of botryococcene synthase enzyme activity, a squalene synthase-like activity from the green microalga Botryococcus braunii, Race B. Arch. Biochem. 2004, 422:110-118.
34. Pirt S.J. The maintenance energy of bacteria in growing cultures. Proc. R. Soc. London. Ser. B 1965, 163:224-231.
35. Reiss L.P. Cocurrent Gas-Liquid Contacting in Packed Columns. Ind. Eng. Chem. Process Des. Dev. 1967, 6:486-499.
36. REN21, 2013. Renewables 2013: global status report. URL <>. http://www.ren21.net/portals/0/documents/resources/gsr/2013/gsr2013_lowres.pdf.
37. Saur, G., 2008. wind-to-hydrogen project: electrolyzer capital cost study. URL <>. http://www.nrel.gov/docs/fy09osti/44103.pdf.
38. Solomon B.D., Barnes J.R., Halvorsen K.E. Grain and cellulosic ethanol: history, economics, and energy policy. Biomass Bioenergy 2007, 31:416-425.
39. Steinbrenner J., Sandmann G. Transformation of the green alga Haematococcus pluvialis with a phytoene desaturase for accelerated astaxanthin biosynthesis. Appl. Environ. Microbiol. 2006, 72:7477-7484.
40. 2 by high cell density autotrophic cultivation of Alcaligenes eutrophus. Biotechnol. Bioeng. 1995, 45:268-275.
41. Tuerk, A., 2011. An Assessment of Photosynthetic Biofuels and Electrofuels Technologies Under Rate-Limited Conditions (thesis), The Pennsylvania State University. URL <>. https://etda.libraries.psu.edu/paper/12318/.
42. Van Bodegom P. Microbial maintenance: a critical review on its quantification. Microb. Ecol. 2007, 53:513-523.
43. Van't Riet K. Review of Measuring Methods and Results in Nonviscous Gas-Liquid Mass Transfer in Stirred Vessels. Ind. Eng. Chem. Process Des. Dev. 1979, 18:357-364.
44. Verwaal R., Wang J., Meijnen J.-P., Visser H., Sandmann G., van den Berg J.A., van Ooyen A.J.J. High-level production of beta-carotene in Saccharomyces cerevisiae by successive transformation with carotenogenic genes from Xanthophyllomyces dendrorhous. Appl. Environ. Microbiol. 2007, 73:4342-4350.