Caffeic acid directly targets ERK1/2 to attenuate solar UV-induced skin carcinogenesis

Cancer Prevention Research

Volumn 7, Issue 10, 2014, Pages 1056-1066

  Yang, Ge ^a,b,c   Fu, Yang ^a,c   Malakhova, Margarita ^a   Kurinov, Igor ^d   Zhu, Feng ^a   Yao, Ke ^a   Li, Haitao ^a   Chen, Hanyong ^a   Li, Wei ^e   Lim, Do Young ^a   Sheng, Yuqiao ^a,b,c   Bode, Ann M ^a   Dong, Ziming ^b   Dong, Zigang ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b ZHENGZHOU UNIVERSITY   (China)

^c THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^d Cornell University ^*  (United States)

^e CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CAFFEIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ANTINEOPLASTIC AGENT; CAFFEIC ACID DERIVATIVE; MAPK1 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INCIDENCE; CHEMOSENSITIVITY; COLONY FORMATION; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTALLIZATION; DRUG TARGETING; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MALIGNANT TRANSFORMATION; MOUSE; MOUSE MODEL; NONHUMAN; PROTEIN EXPRESSION; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; SKIN CANCER; SKIN CARCINOGENESIS; TUMOR VOLUME; TUMOR XENOGRAFT; ULTRAVIOLET RADIATION; ANIMAL; BINDING COMPETITION; CANCER TRANSPLANTATION; CARCINOGENESIS; CHEMISTRY; DRUG EFFECTS; KERATINOCYTE; METABOLISM; NEOPLASMS, RADIATION-INDUCED; NUDE MOUSE; PHOSPHORYLATION; RADIATION RESPONSE; SKIN; SKIN NEOPLASMS;

ANIMALS; ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; CAFFEIC ACIDS; CARCINOGENESIS; CRYSTALLIZATION; FEMALE; HUMANS; KERATINOCYTES; MICE; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEOPLASM TRANSPLANTATION; NEOPLASMS, RADIATION-INDUCED; PHOSPHORYLATION; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SKIN; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 84907519021     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-14-0141     Document Type: Article

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