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Volumn 17, Issue 5, 2014, Pages 649-654

"Quadruple whammy"- A preventable newly described syndrome of post-operative AKI in CKD II and CKD III patients on combination "triple whammy" medications: A Mayo Clinic Health System, Eau Claire, Wisconsin experience

Author keywords

Acute kidney injury; Angiotensin converting enzyme inhibitors; Chronic kidney disease; Diuretics; Non steroidal anti infl ammatory drugs; Post operative hypotension; Quadruple whammy; Serum creatinine; Triple whammy

Indexed keywords

ALKANONE; ANTIHYPERTENSIVE AGENT; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; HYDROCHLOROTHIAZIDE; HYDROCHLOROTHIAZIDE, LISINOPRIL DRUG COMBINATION; LISINOPRIL; NABUMETONE; PYRAZOLE DERIVATIVE; SULFONAMIDE;

EID: 84907514704     PISSN: 11193077     EISSN: None     Source Type: Journal    
DOI: 10.4103/1119-3077.141440     Document Type: Article
Times cited : (9)

References (29)
  • 1
    • 84875908203 scopus 로고    scopus 로고
    • The nephrotoxic "triple whammy" of combining diuretics, ACE inhibitors, and NSAIDs [corrected]
    • Onuigbo MA. The nephrotoxic "triple whammy" of combining diuretics, ACE inhibitors, and NSAIDs [corrected]. BMJ 2013;346:f678
    • (2013) BMJ , vol.346 , pp. f678
    • Onuigbo, M.A.1
  • 2
    • 0034696251 scopus 로고    scopus 로고
    • Diuretics, ACE inhibitors and NSAIDs-The triple whammy
    • Thomas MC. Diuretics, ACE inhibitors and NSAIDs-the triple whammy. Med J Aust 2000;172:184-5
    • (2000) Med J Aust , vol.172 , pp. 184-185
    • Thomas, M.C.1
  • 3
    • 0034605320 scopus 로고    scopus 로고
    • COX-2 inhibitors and renal failure: The triple whammy revisited
    • Boyd IW, Mathew TH, Thomas MC. COX-2 inhibitors and renal failure: The triple whammy revisited. Med J Aust 2000;173:274
    • (2000) Med J Aust , vol.173
    • Boyd, I.W.1    Mathew, T.H.2    Thomas, M.C.3
  • 4
    • 13444263481 scopus 로고    scopus 로고
    • Drug combinations and impaired renal function - The 'triple whammy'
    • Loboz KK, Shenfield GM. Drug combinations and impaired renal function - the 'triple whammy'. Br J Clin Pharmacol 2005;59:239-43
    • (2005) Br J Clin Pharmacol , vol.59 , pp. 239-243
    • Loboz, K.K.1    Shenfield, G.M.2
  • 5
    • 0142198884 scopus 로고    scopus 로고
    • Lessons from early large-scale adoption of celecoxib and rofecoxib by Australian general practitioners
    • Kerr SJ, Mant A, Horn FE, McGeechan K, Sayer GP. Lessons from early large-scale adoption of celecoxib and rofecoxib by Australian general practitioners. Med J Aust 2003;179:403-7
    • (2003) Med J Aust , vol.179 , pp. 403-407
    • Kerr, S.J.1    Mant, A.2    Horn, F.E.3    McGeechan, K.4    Sayer, G.P.5
  • 6
    • 84907539831 scopus 로고    scopus 로고
    • Quadruple Whammy", a new syndrome of potentially preventable yet iatrogenic acute kidney injury in the ICU
    • Rapid Response, Published online. Available From:, [Last accessed on 2013 Feb 25]
    • Onuigbo MA, Onuigbo NT. "Quadruple Whammy", a new syndrome of potentially preventable yet iatrogenic acute kidney injury in the ICU. BMJ 2013: Rapid Response, Published online. Available From: http://www.bmj.com/content/346/bmj.f678/rr/632570 [Last accessed on 2013 Feb 25]
    • (2013) BMJ
    • Onuigbo, M.A.1    Onuigbo, N.T.2
  • 7
    • 84907539830 scopus 로고    scopus 로고
    • A second case of "quadruple Whammy" in a week in a Northwestern Wisconsin hospital
    • Rapid Response, Published online. Available From:, [Last accessed on 2013 Mar 1]
    • Onuigbo MA, Onuigbo NT. A second case of "Quadruple Whammy" in a week in a Northwestern Wisconsin hospital. BMJ 2013: Rapid Response, Published online. Available From: http://www.bmj.com/content/346/bmj.f678/rr/633687. [Last accessed on 2013 Mar 1]
    • (2013) BMJ
    • Onuigbo, M.A.1    Onuigbo, N.T.2
  • 9
    • 84872295339 scopus 로고    scopus 로고
    • Concurrent use of diuretics, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers with non-steroidal anti-inflammatory drugs and risk of acute kidney injury: Nested case-control study
    • Lapi F, Azoulay L, Yin H, Nessim SJ, Suissa S. Concurrent use of diuretics, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers with non-steroidal anti-inflammatory drugs and risk of acute kidney injury: Nested case-control study. BMJ 2013;346:e8525
    • (2013) BMJ , vol.346 , pp. e8525
    • Lapi, F.1    Azoulay, L.2    Yin, H.3    Nessim, S.J.4    Suissa, S.5
  • 10
    • 61649098176 scopus 로고    scopus 로고
    • Reno-prevention vs. Reno-protection: A critical re-appraisal of the evidence-base from the large RAAS blockade trials after ONTARGET-A call for more circumspection
    • Onuigbo MA. Reno-prevention vs. reno-protection: A critical re-appraisal of the evidence-base from the large RAAS blockade trials after ONTARGET-a call for more circumspection. QJM 2009;102:155-67
    • (2009) QJM , vol.102 , pp. 155-167
    • Onuigbo, M.A.1
  • 11
    • 84858973666 scopus 로고    scopus 로고
    • Laboratory monitoring of patients treated with antihypertensive drugs and newly exposed to non steroidal anti-inflammatory drugs: A cohort study
    • Fournier JP, Lapeyre-Mestre M, Sommet A, Dupouy J, Poutrain JC, Montastruc JL. Laboratory monitoring of patients treated with antihypertensive drugs and newly exposed to non steroidal anti-inflammatory drugs: A cohort study. PLoS One 2012;7:e34187
    • (2012) PLoS One , vol.7 , pp. e34187
    • Fournier, J.P.1    Lapeyre-Mestre, M.2    Sommet, A.3    Dupouy, J.4    Poutrain, J.C.5    Montastruc, J.L.6
  • 12
    • 84895534782 scopus 로고    scopus 로고
    • Drug interactions between antihypertensive drugs and non-steroidal anti-inflammatory agents: A descriptive study using the French Pharmacovigilance database
    • Fournier JP, Sommet A, Durrieu G, Poutrain JC, Lapeyre-Mestre M, Montastruc JL. Drug interactions between antihypertensive drugs and non-steroidal anti-inflammatory agents: A descriptive study using the French Pharmacovigilance database. Fundam Clin Pharmacol 2012
    • (2012) Fundam Clin Pharmacol
    • Fournier, J.P.1    Sommet, A.2    Durrieu, G.3    Poutrain, J.C.4    Lapeyre-Mestre, M.5    Montastruc, J.L.6
  • 13
    • 84907539829 scopus 로고    scopus 로고
    • The "triple whammy" challenge revisited - ACEIs, diuretics and NSAIDs: A european 21st century perspective
    • In: Onuigbo MA, editor, New York: NY. NOVA Publishers;
    • Fournier J-P. The "Triple Whammy" Challenge Revisited - ACEIs, Diuretics and NSAIDs: A European 21st Century Perspective. In: Onuigbo MA, editor. ACE inhibitors: Medical uses, mechanisms of action, potential adverse effects and related topics. New York: NY. NOVA Publishers; 2013
    • (2013) ACE Inhibitors: Medical Uses, Mechanisms of Action, Potential Adverse Effects and Related Topics
    • Fournier, J.-P.1
  • 14
    • 84872481961 scopus 로고    scopus 로고
    • Renoprevention: A new concept for reengineering nephrology care-An economic impact and patient outcome analysis of two hypothetical patient management paradigms in the CCU
    • Onuigbo MA. Renoprevention: A new concept for reengineering nephrology care-an economic impact and patient outcome analysis of two hypothetical patient management paradigms in the CCU. Ren Fail 2013;35:23-8
    • (2013) Ren Fail , vol.35 , pp. 23-28
    • Onuigbo, M.A.1
  • 15
    • 26944443877 scopus 로고    scopus 로고
    • Late onset renal failure from angiotensin blockade (LORFFAB): A prospective thirty-month Mayo Health System clinic experience
    • Onuigbo MA, Onuigbo NT. Late onset renal failure from angiotensin blockade (LORFFAB): A prospective thirty-month Mayo Health System clinic experience. Med Sci Monit 2005;11:CR462-9
    • (2005) Med Sci Monit , vol.11 , pp. CR462-CR469
    • Onuigbo, M.A.1    Onuigbo, N.T.2
  • 16
    • 41549134762 scopus 로고    scopus 로고
    • Late-onset renal failure from angiotensin blockade (LORFFAB) in 100 CKD patients
    • Onuigbo MA, Onuigbo NT. Late-onset renal failure from angiotensin blockade (LORFFAB) in 100 CKD patients. Int Urol Nephrol 2008;40:233-9
    • (2008) Int Urol Nephrol , vol.40 , pp. 233-239
    • Onuigbo, M.A.1    Onuigbo, N.T.2
  • 17
    • 38149108349 scopus 로고    scopus 로고
    • Late onset azotemia from RAAS blockade in CKD patients with normal renal arteries and no precipitating risk factors
    • Onuigbo MA, Onuigbo NT. Late onset azotemia from RAAS blockade in CKD patients with normal renal arteries and no precipitating risk factors. Ren Fail 2008;30:73-80
    • (2008) Ren Fail , vol.30 , pp. 73-80
    • Onuigbo, M.A.1    Onuigbo, N.T.2
  • 18
    • 78649521468 scopus 로고    scopus 로고
    • The impact of stopping inhibitors of the renin-angiotensin system in patients with advanced chronic kidney disease
    • Ahmed AK, Kamath NS, El Kossi M, El Nahas AM. The impact of stopping inhibitors of the renin-angiotensin system in patients with advanced chronic kidney disease. Nephrol Dial Transplant 2010;25:3977-82
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 3977-3982
    • Ahmed, A.K.1    Kamath, N.S.2    El Kossi, M.3    El Nahas, A.M.4
  • 19
    • 77950278288 scopus 로고    scopus 로고
    • The impact of stopping inhibitors of the renin-angiotensin system in patients with advanced chronic kidney disease
    • Onuigbo MA. The impact of stopping inhibitors of the renin-angiotensin system in patients with advanced chronic kidney disease. Nephrol Dial Transplant 2010;25:1344-5
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 1344-2135
    • Onuigbo, M.A.1
  • 20
    • 82955217247 scopus 로고    scopus 로고
    • Stopping renin-angiotensin system inhibitors in chronic kidney disease: Predictors of response
    • Gonçalves AR, Khwaja A, Ahmed AK, El Kossi M, El Nahas M. Stopping renin-angiotensin system inhibitors in chronic kidney disease: Predictors of response. Nephron Clin Pract 2011;119:c348-54
    • (2011) Nephron Clin Pract , vol.119 , pp. c348-c354
    • Gonçalves, A.R.1    Khwaja, A.2    Ahmed, A.K.3    El Kossi, M.4    El Nahas, M.5
  • 21
    • 79952324464 scopus 로고    scopus 로고
    • Can ACE inhibitors and angiotensin receptor blockers be detrimental in CKD patients?
    • Onuigbo MA. Can ACE inhibitors and angiotensin receptor blockers be detrimental in CKD patients? Nephron Clin Pract 2011;118:c407-19
    • (2011) Nephron Clin Pract , vol.118 , pp. c407-c419
    • Onuigbo, M.A.1
  • 22
    • 84872295339 scopus 로고    scopus 로고
    • Concurrent use of diuretics, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers with non-steroidal antiinflammatory drugs and risk of acute kidney injury: Nested case-control study
    • January, Rapid Response, Published online January 17 2013
    • Onuigbo MA. Concurrent use of diuretics, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers with non-steroidal antiinflammatory drugs and risk of acute kidney injury: nested case-control study. BMJ January 2013: Rapid Response, Published online January 17 2013. http://www.bmj.com/content/346/bmj.e8525/rr/625431
    • (2013) BMJ
    • Onuigbo, M.A.1
  • 23
    • 84871707306 scopus 로고    scopus 로고
    • Continuous renal-replacement therapy for acute kidney injury
    • Tolwani A. Continuous renal-replacement therapy for acute kidney injury. N Engl J Med 2012;367:2505-14
    • (2012) N Engl J Med , vol.367 , pp. 2505-2514
    • Tolwani, A.1
  • 24
    • 84944152057 scopus 로고    scopus 로고
    • Acute kidney injury on chronic kidney disease-The rainbow syndrome of too many colors: A Mayo Clinic Health System case series report
    • Onuigbo MA, editor, New York: NOVA Publishers
    • Onuigbo MA , Achebe NJ. Acute kidney injury on chronic kidney disease-The rainbow syndrome of too many colors: A Mayo Clinic Health System case series report. In: Onuigbo MA, editor. ACE Inhibitors: Medical Uses, Mechanisms of Action, Potential Adverse Effects and Related Topics. New York: NOVA Publishers; 2013
    • (2013) ACE Inhibitors: Medical Uses, Mechanisms of Action, Potential Adverse Effects and Related Topics
    • Onuigbo, M.A.1    Achebe, N.J.2
  • 26
    • 77957907974 scopus 로고    scopus 로고
    • Perioperative outcomes among patients with the modified metabolic syndrome who are undergoing noncardiac surgery
    • Glance LG, Wissler R, Mukamel DB, Li Y, Diachun CA, Salloum R, et al. Perioperative outcomes among patients with the modified metabolic syndrome who are undergoing noncardiac surgery. Anesthesiology 2010;113:859-72
    • (2010) Anesthesiology , vol.113 , pp. 859-872
    • Glance, L.G.1    Wissler, R.2    Mukamel, D.B.3    Li, Y.4    Diachun, C.A.5    Salloum, R.6
  • 28
    • 84877093010 scopus 로고    scopus 로고
    • Acute kidney injury in patients undergoing cardiac surgery
    • Coppolino G, Presta P, Saturno L, Fuiano G. Acute kidney injury in patients undergoing cardiac surgery. J Nephrol 2013;26:32-40
    • (2013) J Nephrol , vol.26 , pp. 32-40
    • Coppolino, G.1    Presta, P.2    Saturno, L.3    Fuiano, G.4
  • 29
    • 84880570163 scopus 로고    scopus 로고
    • Acute kidney injury, renal function, and the elderly obese surgical patient: A matched case-control study
    • Kelz RR, Reinke CE, Zubizarreta JR, Wang M, Saynisch P, Even-Shoshan O, et al. Acute kidney injury, renal function, and the elderly obese surgical patient: A matched case-control study. Ann Surg 2013;258:359-63.
    • (2013) Ann Surg , vol.258 , pp. 359-363
    • Kelz, R.R.1    Reinke, C.E.2    Zubizarreta, J.R.3    Wang, M.4    Saynisch, P.5    Even-Shoshan, O.6


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