NFκB2/p100 is a key factor for endotoxin tolerance in human monocytes: A demonstration using primary human monocytes from patients with sepsis

Journal of Immunology

Volumn 193, Issue 8, 2014, Pages 4195-4202

  Cubillos Zapata, Carolina ^a   Hernández Jiménez, Enrique ^a   Toledano, Víctor ^a   Esteban Burgos, Laura ^a   Fernández Ruíz, Irene ^a   Gómez Piña, Vanesa ^a   Del Fresno, Carlos ^b   Siliceo, María ^a   Prieto Chinchiñ, Patricia ^c   De Diego, Rebeca Pérez ^a   Boscá, Lisardo ^a,c   Fresno, Manuel ^d   Arnalich, Francisco ^a   López Collazo, Eduardo ^a  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^b CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^c INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^d UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NF KAPPA L CHAIN ENHANCER OF ACTIVATED B CELLS 2; PROTEIN P100; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AGED; ANIMAL CELL; ARTICLE; BACTEREMIA; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG TOLERANCE; ENDOTOXIN TOLERANCE; ESCHERICHIA COLI; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; INFLAMMATION; KNOCKOUT MOUSE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RNA ISOLATION; SEPSIS; URINARY TRACT INFECTION; WESTERN BLOTTING; BIOSYNTHESIS; GENE INACTIVATION; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; RNA INTERFERENCE;

AGED; DOWN-REGULATION; ENDOTOXINS; GENE KNOCKOUT TECHNIQUES; HUMANS; IMMUNE TOLERANCE; INFLAMMATION; MONOCYTES; NF-KAPPA B P52 SUBUNIT; RNA INTERFERENCE; RNA, SMALL INTERFERING; SEPSIS;

EID: 84907487379     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400721     Document Type: Article

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