Adenosine deaminase acting on RNA-1 (ADAR1) Inhibits HIV-1 replication in human alveolar macrophages

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Weiden, Michael D ^a   Hoshino, Satomi ^a   Levy, David N ^b   Li, Yonghua ^a   Kumar, Rajnish ^a,c   Burke, Sean A ^b   Dawson, Rodney ^d   Hioe, Catarina E ^a,c   Borkowsky, William ^a   Rom, William N ^a   Hoshino, Yoshihiko ^a,e  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY COLLEGE OF DENTISTRY   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF CAPE TOWN   (South Africa)

^e NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ADENOSINE DEAMINASE ACTING ON RNA 1; ANTIRETROVIRUS AGENT; CELL ENZYME; ETHAMBUTOL; GUANINE; ISONIAZID; PYRAZINAMIDE; RECOMBINANT GAMMA INTERFERON; RIFAMPICIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ADAR1 PROTEIN, HUMAN; ADENOSINE DEAMINASE; GAMMA INTERFERON; GLYCOPROTEIN GP 120; HIV ENVELOPE PROTEIN GP120 (305-321); ISOPROTEIN; PEPTIDE FRAGMENT; RNA BINDING PROTEIN;

ADJUVANT THERAPY; AEROSOL; ARTICLE; CELL NUCLEUS; CELL TRANSFORMATION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INDUCTION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IN VITRO STUDY; LUNG ALVEOLUS MACROPHAGE; LUNG TUBERCULOSIS; MACROPHAGE; MIXED INFECTION; MONOCYTE; MONOCYTE DERIVED MACROPHAGE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN PROCESSING; T LYMPHOCYTE; VIRUS CELL INTERACTION; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS TRANSCRIPTION; AMINO ACID SUBSTITUTION; BRONCHOALVEOLAR LAVAGE FLUID; CHEMISTRY; CLASSIFICATION; GENE EXPRESSION; GENE SILENCING; GENETICS; GENOTYPE; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; METABOLISM; MUTATION; PHYSIOLOGY; TUBERCULOSIS; VIRAL TROPISM; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ADENOSINE DEAMINASE; AMINO ACID SUBSTITUTION; BRONCHOALVEOLAR LAVAGE FLUID; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GENOTYPE; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HIV-1; HUMANS; INTERFERON-GAMMA; MACROPHAGES, ALVEOLAR; MUTATION; PEPTIDE FRAGMENTS; PROTEIN ISOFORMS; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; TUBERCULOSIS; VIRAL TROPISM; VIRUS REPLICATION;

EID: 84907486322     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108476     Document Type: Article

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