GluA1 phosphorylation contributes to postsynaptic amplification of neuropathic pain in the insular cortex

Journal of Neuroscience

Volumn 34, Issue 40, 2014, Pages 13505-13515

  Qiu, Shuang ^a,b,d   Zhang, Ming ^b,c   Liu, Yan ^c   Guo, Yanyan ^b   Zhao, Huan ^b,c   Song, Qian ^b   Zhao, Minggao ^b   Huganir, Richard L ^e   Luo, Jianhong ^a   Xu, Hui ^b,c   Zhuo, Min ^b,d  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF TORONTO   (Canada)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

GluA1; Insular cortex; Mouse; Neuropathic pain; Phosphorylation; PKA

Indexed keywords

ADENYLATE CYCLASE; AMPA RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; GLUTAMATE RECEPTOR 1; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMINO ACID RECEPTOR BLOCKING AGENT; ENZYME INHIBITOR; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 1; PICROTOXIN; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN;

ADULT; ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CELL FRACTIONATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE DELETION; GENE TRANSLOCATION; INSULA; MALE; MOUSE; NERVE INJURY; NERVE LIGATION; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PERONEUS NERVE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIOIMMUNOPRECIPITATION; SYNAPSE; SYNAPTIC TRANSMISSION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BRAIN CORTEX; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; GENETICS; IN VITRO STUDY; MEMBRANE POTENTIAL; METABOLISM; MUTATION; NEURALGIA; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; TRANSGENIC MOUSE;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; GABA ANTAGONISTS; IN VITRO TECHNIQUES; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEURALGIA; PHOSPHORYLATION; PICROTOXIN; RECEPTORS, AMPA; SODIUM CHANNEL BLOCKERS; SUBCELLULAR FRACTIONS; SYNAPTIC TRANSMISSION; TETRODOTOXIN;

EID: 84907486243     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1431-14.2014     Document Type: Article

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