Caveolin-1 deletion exacerbates cardiac interstitial fibrosis by promoting M2 macrophage activation in mice after myocardial infarction

Current Therapeutic Research - Clinical and Experimental

Volumn 76, Issue , 2014, Pages 84-93

  Shivshankar, Pooja ^a   Halade, Ganesh V ^a,c   Calhoun, Cheresa ^a   Escobar, Gladys P ^a   Mehr, Ali J ^a   Jimenez, Fabio ^a   Martinez, Cindy ^a   Bhatnagar, Harshita ^a   Mjaatvedt, Corey H ^b   Lindsey, Merry L ^a,d   Le Saux, Claude Jourdan ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c University of Alabama at Birmingham   (United States)

^d UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Caveolin 1; Inflammation; Interstitial fibrosis; Macrophage polarization; Myocardial infarction; Transforming growth factor 1 (TGF 1)

Indexed keywords

ARGINASE 1; CAVEOLIN 1; COLLAGEN; INTERLEUKIN 4;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL INVASION; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE EXACERBATION; ECHOCARDIOGRAPHY; FEMALE; FIBROBLAST; GENE DELETION; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE FIBROSIS; HISTOPATHOLOGY; IN VITRO STUDY; INFLAMMATION; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PROTEIN DOMAIN; PROTEIN FUNCTION; ANIMAL; C57BL MOUSE; FIBROSIS; GENE INACTIVATION; GENETICS; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART VOLUME; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ANIMALS; CARDIAC VOLUME; CAVEOLIN 1; FEMALE; FIBROSIS; GENE KNOCKOUT TECHNIQUES; MACROPHAGE ACTIVATION; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; MYOCARDIUM; VENTRICULAR FUNCTION, LEFT;

EID: 84907485564     PISSN: 0011393X     EISSN: 18790313     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2014.07.020     Document Type: Article

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