Clostridium difficile colitis in patients undergoing lumbar spine surgery

Spine

Volumn 39, Issue 19, 2014, Pages

  Skovrlj, Branko ^a   Guzman, Javier Z ^a   Silvestre, Jason ^b   Al Maaieh, Motasem ^a   Qureshi, Sheeraz A ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Clostridium difficile; cost; incidence; infection; lumbar spine; mortality; outcome; spondylosis; stenosis; surgery; trend

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD CLOTTING DISORDER; CLOSTRIDIUM DIFFICILE INFECTION; COLITIS; COMORBIDITY; CONGESTIVE HEART FAILURE; DIABETES MELLITUS; ELIXHAUSER COMORBIDITY INDEX; FEMALE; HOSPITAL CHARGE; HUMAN; KIDNEY FAILURE; LENGTH OF STAY; LUMBAR SPINE; LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; MEDICAID; MEDICALLY UNINSURED; NEUROLOGICAL COMPLICATION; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SPINAL CORD DECOMPRESSION; SPINE FUSION; SPINE SURGERY; CARDIOVASCULAR DISEASES; CLOSTRIDIUM INFECTIONS; CROSS INFECTION; ECONOMICS; HEALTH CARE COST; HOSPITAL; HOSPITAL BED CAPACITY; INCIDENCE; ISOLATION AND PURIFICATION; KIDNEY DISEASES; LUMBAR VERTEBRA; LUNG DISEASES; MICROBIOLOGY; MIDDLE AGED; MORTALITY; OBESITY; PEPTOCLOSTRIDIUM DIFFICILE; POSTOPERATIVE COMPLICATIONS; SPINAL DISEASES; STATISTICS AND NUMERICAL DATA; UNITED STATES;

AGED; CARDIOVASCULAR DISEASES; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; COLITIS; COMORBIDITY; CROSS INFECTION; DIABETES MELLITUS; FEMALE; HEALTH CARE COSTS; HOSPITAL BED CAPACITY; HOSPITAL MORTALITY; HOSPITALS, URBAN; HUMANS; INCIDENCE; KIDNEY DISEASES; LENGTH OF STAY; LUMBAR VERTEBRAE; LUNG DISEASES; MALE; MEDICAID; MEDICALLY UNINSURED; MIDDLE AGED; OBESITY; POSTOPERATIVE COMPLICATIONS; RISK FACTORS; SPINAL DISEASES; SPINAL FUSION; UNITED STATES;

EID: 84907423629     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0000000000000487     Document Type: Article

References (31)

1. Bae HW, Rajaee SS, Kanim LE. Nationwide trends in the surgical management of lumbar spinal stenosis. Spine 2013;38:916-26.
2. Atlas SJ, Keller RB, Robson D, et al. Surgical and nonsurgical management of lumbar spinal stenosis: four-year outcomes from the Maine lumbar spine study. Spine 2000;25:556-62.
3. Bobo LD, Dubberke ER, Kollef M. Clostridium difficile in the ICU: the struggle continues. Chest 2011;140:1643-53.
4. Miller BA. The impact of hospital-onset health care facility associated (HO-HCFA) Clostridium difficile infection (CDI) in community hospitals: surpassing methicillin-resistant Staphylococcus aureus (MRSA) as the new superbug. Paper presented at: Fifth International Conference on Healthcare-Associated Infections (ICHAI); March 20, 2010;Atlanta, GA.
5. Lo Vecchio A, Zacur GM. Clostridium difficile infection: an update on epidemiology, risk factors, and therapeutic options. Curr Opin Gastroenterol 2012;28:1-9.
6. Maltenfort MG, Rasouli MR, Morrison TA, et al. Clostridium difficile colitis in patients undergoing lower-extremity arthroplasty: rare infection with major impact. Clin Orthop Relat Res 2013;471:3178-85.
7. Griniatsos J, Dimitriou N, Tyritzis S, et al. Toxic megacolon due to fulminant Clostridium difficile colitis. Acta Gastroenterol Belg 2011;74:359-60.
8. Jobe BA, Grasley A, Deveney KE, et al. Clostridium difficile colitis: an increasing hospital-acquired illness. Am J Surg 1995;169:480-3.
9. Morris AM, Jobe BA, Stoney M, et al. Clostridium difficile colitis: an increasingly aggressive iatrogenic disease? Arch Surg 2002;137:1096-100.
10. Wang L, Stewart DB. Increasing hospital costs for Clostridium difficile colitis: type of hospital matters. Surgery 2011;150:727-35.
11. Zerey M, Paton BL, Lincourt AE, et al. The burden of Clostridium difficile in surgical patients in the United States. Surg Infect 2007;8:557-66.
12. HCUP Nationwide Inpatient Sample (NIS). Healthcare Cost and Utilization Project (HCUP). Rockville, MD: Agency for Healthcare Research and Quality. 2002-2011. Available at: www.hcup-us.ahrq.gov/nisoverview.jsp. Accessed February 23, 2014.
13. van Walraven C, Austin PC, Jennings A, et al. A modification of the Elixhauser comorbidity measures into a point system for hospital death using administrative data. Med Care 2009;47:626-33.
14. Elixhauser A, Steiner C, Harris DR, et al. Comorbidity measures for use with administrative data. Med Care 1998;36:8-27.
15. Sharabiani MT, Aylin P, Bottle A. A systematic review of comorbidity indices for administrative data. Med Care 2012;50:1109-18.
16. HCUP Cost-to-Ratio Files (CCR). Healthcare Cost and Utilization Project (HCUP). Rockville, MD: Agency for Healthcare Research and Quality; 2002-2011. Available at: http://www.hcup-us.ahrq.gov/db/state/costtocharge.jsp. Accessed August 1, 2014.
17. Bureau of Labor Statistics. CPI inflation calculator. 2006. Available at: http//:data.bls.gov/cgi-bin/cpicalc.pl. Accessed December 19, 2013.
18. Carignan A, Allard C, Pepin J, et al. Risk of Clostridium difficile infection after perioperative antibacterial prophylaxis before and during an outbreak of infection due to a hypervirulent strain. Clin Infect Dis 2008;46:1838-43.
19. Pepin J, Valiquette L, Alary ME, et al. Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003:a changing pattern of disease severity. CMAJ 2004;171:466-72.
20. Pepin J, Valiquette L, Cossette B. Mortality attributed to nosocomial Clostridium difficile-associated disease during an epidemic caused by a hypervirulent strain in Quebec. CMAJ 2005;173:1037-42.
21. Clark HJ, Jinnah RH, Byank RP, et al. Clostridium difficile infection in orthopaedic patients. J Bone Joint Surg Am 1990;72:1056-59.
22. Stewart DB, Hollenbeak CS. Clostridium difficile colitis: factors associated with outcome and assessment of mortality at a national level. J Gastrointest Surg 2011;15:1548-55.
23. Hassan SA, Rahman RA, Huda N, et al. Hospital-acquired Clostridium difficile infection among patients with type 2 diabetes mellitus in acute medical wards. J R Coll Physicians Edinb 2013;43:103-7.
24. Shakov R, Salazar RS, Kagunye SK, et al. Diabetes mellitus as a risk factor for recurrence of Clostridium difficile infection in the acute care hospital setting. Am J Infect Control 2011;39:194-8.
25. Mullane KM, Cornely OA, Crook DW, et al. Renal impairment and clinical outcomes of Clostridium difficile in two randomized trials. Am J Nephrol 2011;38:1-11.
26. Keddis MT, Khanna S, Noheria A, et al. Clostridium difficile infection in patients with chronic kidney disease. Mayo Clin Proc 2012;87:1046-53.
27. Kurd MF, Pulido L, Joshi A, et al. Clostridium difficile infection after total joint arthroplasty: United States from 2005 to 2030. J Bone Joint Surg Am 2007;89:780-5.
28. Slobogean GP, Kennedy SA, Davidson D, et al. Single-versus multiple-dose antibiotic prophylaxis in the treatment of closed fractures: a meta-analysis. J Orthop Trauma 2008;22:264-9.
29. Al-Obaydi W, Smith CD, Foguet P. Changing prophylactic antibiotic protocol for reducing Clostridium difficile-associated diarrheal infections. J Orthop Surg (Hong Kong) 2010;18:320-3.
30. Ricciardi R, Rothenberger DA, Madoff RD, et al. Increasing prevalence and severity of Clostridium difficile colitis in hospitalized patients in the United States. Arch Surg 2007;142:624-31.
31. American Society of Health-System Pharmacists. Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery. Bethesda, MD; ASHP. 2012. Available at: http://www.ashp.org/DocLibrary/BestPractices/TGSurgery.aspx. Accessed February 23, 2014.