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Volumn 34, Issue 5, 2014, Pages 565-570

Exposure to anticholinergic and sedative drugs, risk of falls, and mortality: An elderly inpatient, multicenter cohort

Author keywords

aging; anticholinergic drugs; falls; safety management; sedative drugs

Indexed keywords

CHOLINERGIC RECEPTOR BLOCKING AGENT; SEDATIVE AGENT; HYPNOTIC SEDATIVE AGENT;

EID: 84907423440     PISSN: 02710749     EISSN: 1533712X     Source Type: Journal    
DOI: 10.1097/JCP.0000000000000195     Document Type: Article
Times cited : (58)

References (43)
  • 1
    • 0345731432 scopus 로고    scopus 로고
    • Inappropriate medication use among frail elderly inpatients
    • Hanlon JT, ArtzMB, Pieper CF, et al. Inappropriate medication use among frail elderly inpatients. Ann Pharmacother. 2004;38:9-14.
    • (2004) Ann Pharmacother , vol.38 , pp. 9-14
    • Hanlon, J.T.1    Artzmb Pieper, C.F.2
  • 2
    • 27644480374 scopus 로고    scopus 로고
    • Impact of inappropriate drug use among hospitalized older adults
    • OnderG, Landi F, Liperoti R, et al. Impact of inappropriate drug use among hospitalized older adults. Eur J Clin Pharmacol. 2005;61:453-459.
    • (2005) Eur J Clin Pharmacol , vol.61 , pp. 453-459
    • Onderg Landi, F.1    Liperoti, R.2
  • 3
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
    • Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies. JAMA. 1998; 279:1200-1205.
    • (1998) JAMA , vol.279 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 4
    • 0042707810 scopus 로고    scopus 로고
    • When drug therapy gets old: Pharmacokinetics and pharmacodynamics in the elderly
    • Turnheim K. When drug therapy gets old: Pharmacokinetics and pharmacodynamics in the elderly. Exp Gerontol. 2003;38:843-853.
    • (2003) Exp Gerontol , vol.38 , pp. 843-853
    • Turnheim, K.1
  • 5
    • 33846042587 scopus 로고    scopus 로고
    • Is inappropriate medication use a major cause of adverse drug reactions in the elderly?
    • LarocheML, Charmes JP, Nouaille Y, et al. Is inappropriate medication use a major cause of adverse drug reactions in the elderly? Br J Clin Pharmacol. 2007;63:177-186.
    • (2007) Br J Clin Pharmacol , vol.63 , pp. 177-186
    • Laroche, M.L.1    Charmes, J.P.2    Nouaille, Y.3
  • 7
    • 84874948673 scopus 로고    scopus 로고
    • Falls among adult patients hospitalized in the United States: Prevalence and trends
    • Bouldin EL, Andresen EM, Dunton NE, et al. Falls among adult patients hospitalized in the United States: Prevalence and trends. J Patient Saf. 2013;9:13-17.
    • (2013) J Patient Saf , vol.9 , pp. 13-17
    • Bouldin, E.L.1    Andresen, E.M.2    Dunton, N.E.3
  • 8
    • 33846293306 scopus 로고    scopus 로고
    • Strategies to prevent falls and fractures in hospitals and care homes and effect of cognitive impairment: Systematic review and meta-analyses
    • Oliver D, Connelly JB, Victor CR, et al. Strategies to prevent falls and fractures in hospitals and care homes and effect of cognitive impairment: Systematic review and meta-analyses. BMJ. 2007;334:82.
    • (2007) BMJ , vol.334 , pp. 82
    • Oliver, D.1    Connelly, J.B.2    Victor, C.R.3
  • 9
    • 79952508981 scopus 로고    scopus 로고
    • The cost of serious fall-related injuries at three Midwestern hospitals
    • Wong CA, Recktenwald AJ, JonesML, et al. The cost of serious fall-related injuries at three Midwestern hospitals. Jt Comm J Qual Patient Saf. 2011; 37:81-87.
    • (2011) Jt Comm J Qual Patient Saf , vol.37 , pp. 81-87
    • Wong, C.A.1    Recktenwald, A.J.2    Jones, M.L.3
  • 10
    • 0037326921 scopus 로고    scopus 로고
    • Predictors of a nursing home placement from a non-acute geriatric hospital
    • Aditya BS, Sharma JC, Allen SC, et al. Predictors of a nursing home placement from a non-acute geriatric hospital. Clin Rehabil. 2003;17:108-113.
    • (2003) Clin Rehabil , vol.17 , pp. 108-113
    • Aditya, B.S.1    Sharma, J.C.2    Allen, S.C.3
  • 11
    • 0029153512 scopus 로고
    • Serious falls in hospitalized patients: Correlates and resource utilization
    • Bates D, Pruess K, Souney P, et al. Serious falls in hospitalized patients: Correlates and resource utilization. Am J Med. 1995;99:137-143.
    • (1995) Am J Med , vol.99 , pp. 137-143
    • Bates, D.1    Pruess, K.2    Souney, P.3
  • 12
    • 84865219960 scopus 로고    scopus 로고
    • Is it possible to identify risks for injurious falls in hospitalized patients?
    • Mion LC, ChandlerAM,Waters TM, et al. Is it possible to identify risks for injurious falls in hospitalized patients?. Jt Comm J Qual Patient Saf. 2012; 38:408-413.
    • (2012) Jt Comm J Qual Patient Saf , vol.38 , pp. 408-413
    • Mion, L.C.1    Chandler, A.M.2    Waters, T.M.3
  • 13
    • 20544445759 scopus 로고    scopus 로고
    • Psychotropic medications and risk of falls among community-dwelling frail older people: An observational study
    • Landi F, Onder G, Cesari M, et al. Psychotropic medications and risk of falls among community-dwelling frail older people: An observational study. J Gerontol A Biol Sci Med Sci. 2005;60:622-626.
    • (2005) J Gerontol A Biol Sci Med Sci , vol.60 , pp. 622-626
    • Landi, F.1    Onder, G.2    Cesari, M.3
  • 15
    • 79951913300 scopus 로고    scopus 로고
    • Effects of anticholinergic drugs on verbal episodic memory function in the elderly: A retrospective, cross-sectional study
    • Fortin MP, Rouch I, Dauphinot V, et al. Effects of anticholinergic drugs on verbal episodic memory function in the elderly: A retrospective, cross-sectional study. Drugs Aging. 2011;28:195-204.
    • (2011) Drugs Aging , vol.28 , pp. 195-204
    • Fortin, M.P.1    Rouch, I.2    Dauphinot, V.3
  • 16
    • 68949118279 scopus 로고    scopus 로고
    • Inappropriate medication use and risk of falls a prospective study in a large community-dwelling elderly cohort
    • Berdot S, BertrandM, Dartigues JF, et al. Inappropriate medication use and risk of falls-a prospective study in a large community-dwelling elderly cohort. BMC Geriatr. 2009;23:30.
    • (2009) BMC Geriatr , vol.23 , pp. 30
    • Berdot, S.1    Bertrand, M.2    Dartigues, J.F.3
  • 17
    • 0036799385 scopus 로고    scopus 로고
    • Drugs and falls: Rethinking the approach to medication risk in older adults
    • Agostini JV, Tinetti ME. Drugs and falls: Rethinking the approach to medication risk in older adults. J Am Geriatr Soc. 2002;50:1744-1745.
    • (2002) J Am Geriatr Soc , vol.50 , pp. 1744-1745
    • Agostini, J.V.1    Tinetti, M.E.2
  • 18
    • 67749103704 scopus 로고    scopus 로고
    • Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: The 3-city study
    • Carriere I, Fourrier-Reglat A, Dartigues JF, et al. Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: The 3-city study. Arch Intern Med. 2009;169:1317-1324.
    • (2009) Arch Intern Med , vol.169 , pp. 1317-1324
    • Carriere, I.1    Fourrier-Reglat, A.2    Dartigues, J.F.3
  • 19
    • 84885174473 scopus 로고    scopus 로고
    • Pharmaceutical sales representatives and patient safety: A comparative prospective study of information quality in Canada, France and the United States
    • Mintzes B, Lexchin J, Sutherland JM, et al. Pharmaceutical sales representatives and patient safety: A comparative prospective study of information quality in Canada, France and the United States. J Gen Intern Med. 2013;28:1368-1375.
    • (2013) J Gen Intern Med , vol.28 , pp. 1368-1375
    • Mintzes, B.1    Lexchin, J.2    Sutherland, J.M.3
  • 20
    • 34247547047 scopus 로고    scopus 로고
    • A drug burden index to define the functional burden of medications in older people
    • Hilmer SN, Mager DE, Simonsick EM, et al. A drug burden index to define the functional burden of medications in older people. Arch Intern Med. 2007;167:781-787.
    • (2007) Arch Intern Med , vol.167 , pp. 781-787
    • Hilmer, S.N.1    Mager, D.E.2    Simonsick, E.M.3
  • 21
    • 79955982494 scopus 로고    scopus 로고
    • Associations between drug burden index and falls in older people in residential aged care
    • Wilson NM, Hilmer SN, March LM, et al. Associations between drug burden index and falls in older people in residential aged care. JAmGeriatr Soc. 2011;59:875-880.
    • (2011) JAmGeriatr Soc , vol.59 , pp. 875-880
    • Wilson, N.M.1    Hilmer, S.N.2    March, L.M.3
  • 22
    • 72049093999 scopus 로고    scopus 로고
    • Drug burden index score and functional decline in older people
    • Hilmer SN, Mager DE, Simonsick EM, et al. Drug burden index score and functional decline in older people. Am J Med. 2009;122:1142-1149.
    • (2009) Am J Med , vol.122 , pp. 1142-1149
    • Hilmer, S.N.1    Mager, D.E.2    Simonsick, E.M.3
  • 23
    • 84863419766 scopus 로고    scopus 로고
    • Effects of drug burden index on cognitive function in older men
    • Gnjidic D, Le Couteur DG, Naganathan V, et al. Effects of drug burden index on cognitive function in older men. J Clin Phychopharmacol. 2012; 32:273-277.
    • (2012) J Clin Phychopharmacol , vol.32 , pp. 273-277
    • Gnjidic, D.1    Le Couteur, D.G.2    Naganathan, V.3
  • 24
    • 84857238588 scopus 로고    scopus 로고
    • High-risk prescribing and incidence of frailty among older community-dwelling men
    • Gnjidic D, Hilmer SN, Blyth FM, et al. High-risk prescribing and incidence of frailty among older community-dwelling men. Clin Pharmacol Ther. 2012;91:521-528.
    • (2012) Clin Pharmacol Ther , vol.91 , pp. 521-528
    • Gnjidic, D.1    Hilmer, S.N.2    Blyth, F.M.3
  • 25
    • 84863012031 scopus 로고    scopus 로고
    • Associations between drug burden index and mortality in older people in residential aged care facilities
    • Wilson NM, Hilmer SN, March LM, et al. Associations between drug burden index and mortality in older people in residential aged care facilities. Drugs Aging 2012;29:157-165.
    • (2012) Drugs Aging , vol.29 , pp. 157-165
    • Wilson, N.M.1    Hilmer, S.N.2    March, L.M.3
  • 26
    • 84870458315 scopus 로고    scopus 로고
    • Drug burden index, physical function, and adverse outcomes in older hospitalized patients
    • Lowry E, Woodman RJ, Soiza RL, et al. Drug burden index, physical function, and adverse outcomes in older hospitalized patients. J Clin Pharmacol 2012;52:1584-1591.
    • (2012) J Clin Pharmacol , vol.52 , pp. 1584-1591
    • Lowry, E.1    Woodman, R.J.2    Soiza, R.L.3
  • 27
    • 84880277651 scopus 로고    scopus 로고
    • A standard international version of drug burden index for cross-sectional comparison of the functional burden of medications in older people
    • Faure R, Dauphinot V, Krolak-Salmon P, et al. A standard international version of drug burden index for cross-sectional comparison of the functional burden of medications in older people. J Am Geriatr Soc. 2013; 61:1227-1228.
    • (2013) J Am Geriatr Soc , vol.61 , pp. 1227-1228
    • Faure, R.1    Dauphinot, V.2    Krolak-Salmon, P.3
  • 28
    • 84871994905 scopus 로고    scopus 로고
    • Zolpidem is independently associated with increased risk of inpatient falls
    • Kolla BP, Lovely JK, Mansukhani MP, et al. Zolpidem is independently associated with increased risk of inpatient falls. J Hosp Med. 2013;8:1-6.
    • (2013) J Hosp Med , vol.8 , pp. 1-6
    • Kolla, B.P.1    Lovely, J.K.2    Mansukhani, M.P.3
  • 29
    • 70349329580 scopus 로고    scopus 로고
    • Medication use and increased risk of falls in hospitalized elderly patients: A retrospective, case-control study
    • Rhalimi M, Helou R, Jaecker P. Medication use and increased risk of falls in hospitalized elderly patients: A retrospective, case-control study. Drugs Aging. 2009;26:847-852.
    • (2009) Drugs Aging , vol.26 , pp. 847-852
    • Rhalimi, M.1    Helou, R.2    Jaecker, P.3
  • 30
    • 79953833792 scopus 로고    scopus 로고
    • Medical conditions and medications as risk factors of falls in the inpatient older people: A case-control study
    • Chang CM, Chen MJ, Tsai CY, et al. Medical conditions and medications as risk factors of falls in the inpatient older people: A case-control study. Int J Geriatr Psychiatry. 2011;26:602-607.
    • (2011) Int J Geriatr Psychiatry , vol.26 , pp. 602-607
    • Chang, C.M.1    Chen, M.J.2    Tsai, C.Y.3
  • 31
    • 0037315114 scopus 로고    scopus 로고
    • Serum anticholinergic activity in a community-based sample of older adults: Relationship with cognitive performance
    • Mulsant BH, Pollock BG, KirshnerM, et al. Serum anticholinergic activity in a community-based sample of older adults: Relationship with cognitive performance. Arch Gen Psychiatry. 2003;60:198-203.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 198-203
    • Mulsant, B.H.1    Pollock, B.G.2    Kirshner, M.3
  • 32
    • 84862880757 scopus 로고    scopus 로고
    • Safety and tolerability of antipsychotic pharmacy
    • Gallego JA, Nielsen J, De Hert M, et al. Safety and tolerability of antipsychotic pharmacy. Expert Opin Drug Saf. 2012;11:527-542.
    • (2012) Expert Opin Drug Saf , vol.11 , pp. 527-542
    • Gallego, J.A.1    Nielsen, J.2    De Hert, M.3
  • 33
    • 16544367049 scopus 로고    scopus 로고
    • Pharmacologic management of insomnia
    • Walsj JK. Pharmacologic management of insomnia. J Clin Psychiatry. 2004;65:41-45.
    • (2004) J Clin Psychiatry , vol.65 , pp. 41-45
    • Walsj, J.K.1
  • 34
    • 84859717078 scopus 로고    scopus 로고
    • Outcomes of polypharmacy in nursing home residents
    • Tamura BK, Bell CL, Inaba M, et al. Outcomes of polypharmacy in nursing home residents. Clin Geriatr Med. 2012;28:217-236.
    • (2012) Clin Geriatr Med , vol.28 , pp. 217-236
    • Tamura, B.K.1    Bell, C.L.2    Inaba, M.3
  • 35
    • 33644922935 scopus 로고    scopus 로고
    • Polypharmacy and falls in the middle age and elderly population
    • Ziere G, Dieleman JP, Hofman A, et al. Polypharmacy and falls in the middle age and elderly population. Br J Clin Pharmacol. 2006;61: 218-223.
    • (2006) Br J Clin Pharmacol , vol.61 , pp. 218-223
    • Ziere, G.1    Dieleman, J.P.2    Hofman, A.3
  • 36
    • 84892706799 scopus 로고    scopus 로고
    • Investigating polypharmacy and drug burden index in hospitalised older people
    • Best O, Gnjidic D, Hilmer SN, et al. Investigating polypharmacy and drug burden index in hospitalised older people. Intern Med J. 2013;43:912-918.
    • (2013) Intern Med J , vol.43 , pp. 912-918
    • Best, O.1    Gnjidic, D.2    Hilmer, S.N.3
  • 37
    • 84255204768 scopus 로고    scopus 로고
    • Psychotropic drug-induced falls in older people: A review of interventions aimed at reducing the problem
    • Hill KD,Wee R. Psychotropic drug-induced falls in older people: A review of interventions aimed at reducing the problem. Drugs Aging. 2012;29: 15-30.
    • (2012) Drugs Aging , vol.29 , pp. 15-30
    • Hill Kdwee, R.1
  • 38
    • 80054950171 scopus 로고    scopus 로고
    • Withdrawal of psychotropic drugs decreases the risk of falls requiring treatment
    • Salonoja M, Salminen M, Vahlberg T, et al. Withdrawal of psychotropic drugs decreases the risk of falls requiring treatment. Arch Gerontol Geriatr. 2012;54:160-167.
    • (2012) Arch Gerontol Geriatr , vol.54 , pp. 160-167
    • Salonoja, M.1    Salminen, M.2    Vahlberg, T.3
  • 39
    • 84860514785 scopus 로고    scopus 로고
    • The role of cognitive impairment in fall risk among older adults: A systematic review and meta-analysis
    • Muir SW, Gopaul K, Montero Odasso MM. The role of cognitive impairment in fall risk among older adults: A systematic review and meta-analysis. Age Ageing. 2012;41:299-308.
    • (2012) Age Ageing , vol.41 , pp. 299-308
    • Muir, S.W.1    Gopaul, K.2    Montero Odasso, M.M.3
  • 40
    • 0035984842 scopus 로고    scopus 로고
    • Falls in cognitive impairment and dementia
    • Shaw FE. Falls in cognitive impairment and dementia. Clin Geriatr Med. 2002;18:159-173.
    • (2002) Clin Geriatr Med , vol.18 , pp. 159-173
    • Shaw, F.E.1
  • 41
    • 0035788616 scopus 로고    scopus 로고
    • Prospective assessment of falls in Parkinson's disease
    • Bloem BR, Grimbergen YA, Cramer M, et al. Prospective assessment of falls in Parkinson's disease. J Neurol. 2001;248:950-958.
    • (2001) J Neurol , vol.248 , pp. 950-958
    • Bloem, B.R.1    Grimbergen, Y.A.2    Cramer, M.3
  • 42
    • 0036259137 scopus 로고    scopus 로고
    • Incidence and prediction of falls in Parkinson's disease: A prospective multidisciplinary study
    • Wood BH, Bilclough JA, Bowron A, et al. Incidence and prediction of falls in Parkinson's disease: A prospective multidisciplinary study. J Neurol Neurosurg Psychiatry. 2002;72:721-725.
    • (2002) J Neurol Neurosurg Psychiatry , vol.72 , pp. 721-725
    • Wood, B.H.1    Bilclough, J.A.2    Bowron, A.3
  • 43
    • 61449171103 scopus 로고    scopus 로고
    • Falls in English and Welsh hospitals: A national observational study based on retrospective analysis of 12months of patient safety incident reports
    • Healey F, Scobie S, Oliver D, et al. Falls in English and Welsh hospitals: A national observational study based on retrospective analysis of 12months of patient safety incident reports. Qual Saf Health Care. 2008; 17:424-430.
    • (2008) Qual Saf Health Care , vol.17 , pp. 424-430
    • Healey, F.1    Scobie, S.2    Oliver, D.3


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