Inappropriate Medication Use among Frail Elderly Inpatients

Annals of Pharmacotherapy

Volumn 38, Issue 1, 2004, Pages 9-14

  Hanlon, Joseph T ^a,b,c   Artz, Margaret B ^b   Pieper, Carl F ^a,d   Lindblad, Catherine I ^b,c   Sloane, Richard J ^d   Ruby, Christine M ^d,e,f   Schmader, Kenneth E ^d,f  

^a Dept of Exp and Clin Pharmacology ^*

^b UNIVERSITY OF MINNESOTA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF NORTH CAROLINA   (United States)

^f Ctr Stud Aging/Hum Devmt   (United States)

Author keywords

Drug utilization; Elderly; Epidemiology; Quality of care

Indexed keywords

DRUG;

AGED; ARTICLE; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; CLASSIFICATION; DEMOGRAPHY; DRUG USE; DRUG UTILIZATION; FEMALE; GASTROINTESTINAL TRACT; HEALTH CARE QUALITY; HEALTH STATUS; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; INFORMATION PROCESSING; MAJOR CLINICAL STUDY; MALE; MEDICATION ERROR; PATIENT; PHARMACIST; PHYSICIAN; POLYPHARMACY; PRESCRIPTION; PREVALENCE; PRIORITY JOURNAL; PUBLIC RELATIONS; SOLDIER;

EID: 0345731432     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1D313     Document Type: Article

References (24)

1. Hanlon JT, Schmader KE, Samsa G, Weinberger M, Uttech K, Lewis IK, et al. A method for assessing drug therapy appropriateness. J Clin Epidemiol 1992;45:1045-51.
2. Schmader K, Hanlon JT, Weinberger M, Landsman PB, Samsa GP, Lewis I, et al. Appropriateness of medication prescribing in ambulatory elderly patients. J Am Geriatr Soc 1994;42:1241-7.
3. Hanlon JT, Schmader KE, Ruby CM, Weinberger M. Suboptimal prescribing in elderly inpatients and outpatients. J Am Geriatr Soc 2001;49:200-9.
4. Avorn J, Gurwitz JH. Drug use in the nursing home. Ann Intern Med 1995;123:195-204.
5. Edwards RF, Harrison TM, Davis SM. Potentially inappropriate prescribing for geriatric inpatients: an acute care of the elderly unit compared to a general medicine service. Consult Pharm 2003;18:37-42, 47-9.
6. Oborne CA, Batty GM, Maskrey V, Swift CG, Jackson SH. Development of prescribing indicators for elderly medical inpatients. Br J Clin Pharmacol 1997;43:91-7.
7. Owens NJ, Sherburne NJ, Silliman RA, Fretwell MD. The senior care study: the optimal use of medications in acutely ill older patients. J Am Geriatr Soc 1990;38:1082-7.
8. Schmader KE, Hanlon JT, Pieper CF, Sloane R, Ruby CM, Twersky J, et al. Effectiveness of geriatric evaluation and management on adverse drug reactions and suboptimal prescribing in the frail elderly. Am J Med (in press).
9. Cohen HJ, Feussner JR, Weinberger M, Carnes M, Hamdy RC, Hsieh F, et al. A controlled trial of inpatient and outpatient geriatric evaluation and management. N Engl J Med 2002;346:905-12.
10. Samsa G, Hanlon JT, Schmader KE, Weinberger M, Clipp EC, Uttech K, et al. A summated score for the Medication Appropriateness Index: development and assessment of clinimetric properties including content validity. J Clin Epidemiol 1994;47:891-6.
11. Beers MH. Explicit criteria for determining potentially inappropriate medication by the elderly. Arch Int Med 1997;157:1531-6.
12. Andersen RM. Revisiting the behavioral model and access to medical care: does it matter? J Health Soc Behav 1995;36:1-10.
13. Charlson ME, Pompei P, Ales KL, MacKenzie CB. A new method for classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373-83.
14. Katz S, Akpom CA. A measure of primary sociobiologic functions. Int J Health Serv 1976;6:493-507.
15. Veterans Affairs Medication Classification System. In. USP drug information. 20th ed. Appendix IV. Rockville, MD: MICROMEDEX Thompson Healthcare 2000:3220-37.
16. Kleinbaum DG, Kupper LL, Muller KE. Applied liner regression analysis and other multivariable methods. Belmont, CA: Duxbury Press, 1988.
17. Sweitzer NK, Frishman WH, Stevenson LW. Drug therapy of heart failure caused by systolic dysfunction in the elderly. Clin Geriatr Med 2000;16:513-34.
18. Chertow GM, Lee J, Kuperman GJ, Burdick E, Horsky J, Seger DL, et al. Guided medication dosing for inpatients with renal insufficiency. JAMA 2001;286:2839-44.
19. Fijn R, Van den Bemt PM, Chow M, De Blaey CJ, De Jong-Van den Berg LT, Brouwers JR. Hospital prescribing errors: epidemiological assessment of predictors. Br J Clin Pharmacol 2002;53:326-31.
20. Tamblyn RM, McLeod PJ, Abrahamowicz M, Monette J, Gayton DC, Berkson L, et al. Questionable prescribing for elderly patients in Quebec. Can Med Assoc J 1994;150:1801-9.
21. Kirking DM, Ascione FJ. Evaluating variables associated with potential drug-related problems in an older population. J Geriatr Drug Ther 1995;9:29-45.
22. Stuck AE, Beers MH, Steiner A, Aronow HU, Rubenstein LZ, Beck JC. Inappropriate medication use in community residing older persons. Arch Intern Med 1994;154:2195-200.
23. Hanlon JT, Schmader KE, Boult C, Artz MB, Gross CR, Fillenbaum GG, et al. Use of inappropriate prescription drugs by older people. J Am Geriatr Soc 2002;50:26-34.
24. Aparasu RR, Sitzman SJ. Inappropriate prescribing for elderly outpatients. Am J Health Syst Pharm 1999;56:433-9.