Inappropriate medication use and risk of falls - A prospective study in a large community-dwelling elderly cohort

BMC Geriatrics

Volumn 9, Issue 1, 2009, Pages

  Berdot, Sarah ^a,b   Bertrand, Marion ^a,b   Dartigues, Jean François ^a   Fourrier, Annie ^c   Tavernier, Béatrice ^d   Ritchie, Karen ^e   Alpérovitch, Annick ^a,b  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITÉ DE BORDEAUX   (France)

^d DIJON UNIVERSITY HOSPITAL   (France)

^e Montpellier 1 University   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; CHOLINERGIC RECEPTOR BLOCKING AGENT; HYPNOTIC AGENT; NEUROLEPTIC AGENT; VASODILATOR AGENT; PRESCRIPTION DRUG; PSYCHOTROPIC AGENT;

AGED; ANTICHOLINERGIC EFFECT; ARTICLE; DEMOGRAPHY; DEPRESSION; DOSE RESPONSE; DRUG USE; FALLING; FEMALE; FOLLOW UP; FRANCE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICATION ERROR; PRESCRIPTION; PROSPECTIVE STUDY; SELF REPORT; SOCIAL ASPECT; CLINICAL TRIAL; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; STATISTICS;

ACCIDENTAL FALLS; AGED; AGED, 80 AND OVER; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MEDICATION ERRORS; PRESCRIPTION DRUGS; PROSPECTIVE STUDIES; PSYCHOTROPIC DRUGS; RESIDENCE CHARACTERISTICS; RISK FACTORS;

EID: 68949118279     PISSN: None     EISSN: 14712318     Source Type: Journal    
DOI: 10.1186/1471-2318-9-30     Document Type: Article

References (49)

1. National health expenditures, 1988. Office of National Cost Estimates. RH Arnett III LA Blank AP Brown, Health Care Financ Rev 1990 11 1 41
2. Elderly people and drugs (Personnes gées et médicaments). Académie nationale de Pharmacie, 2005 http://www.acadpharm.org/
3. Suboptimal prescribing in older inpatients and outpatients. JT Hanlon KE Schmader CM Ruby M Weinberger, J Am Geriatr Soc 2001 49 200 209
4. Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine. MH Beers JG Ouslander I Rollingher DB Reuben J Brooks JC Beck, Arch Intern Med 1991 151 1825 1832
5. Explicit criteria for determining potentially inappropriate medication use by the elderly. An update. MH Beers, Arch Intern Med 1997 157 1531 1536
6. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. DM Fick JW Cooper WE Wade JL Waller JR Maclean MH Beers, Arch Intern Med 2003 163 2716 2724
7. Potentially inappropriate medications in the elderly: a French consensus panel list. ML Laroche JP Charmes L Merle, Eur J Clin Pharmacol 2007 63 725 73117554532
8. Defining inappropriate practices in prescribing for elderly people: a national consensus panel. PJ McLeod AR Huang RM Tamblyn DC Gayton, CMAJ 1997 156 385 391
9. Inappropriate prescribing for elderly Americans in a large outpatient population. LH Curtis T Ostbye V Sendersky, Arch Intern Med 2004 164 1621 1625
10. Potentially inappropriate medication use among elderly home care patients in Europe. D Fialova E Topinkova G Gambassi, JAMA 2005 293 1348 1358 (Pubitemid 40381487)
11. Frequency and risk factors of potentially inappropriate medication use in a community-dwelling elderly population: results from the 3C Study. N Lechevallier-Michel M Gautier-Bertrand A Alperovitch, Eur J Clin Pharmacol 2005 60 813 819
12. Inappropriate medication use among hospitalized older adults in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly. G Onder F Landi M Cesari G Gambassi P Carbonin R Bernabei, Eur J Clin Pharmacol 2003 59 157 162
13. Trends in the prescription of inappropriate drugs for the elderly between 1995 and 1999. B Stuart S Kamal-Bahl B Briesacher, Am J Geriatr Pharmacother 2003 1 61 74
14. Is inappropriate medication use a major cause of adverse drug reactions in the elderly? ML Laroche JP Charmes Y Nouaille N Picard L Merle, Br J Clin Pharmacol 2007 63 177 186
15. Hospitalization and death associated with potentially inappropriate medication prescriptions among elderly nursing home residents. DT Lau JD Kasper DE Potter A Lyles RG Bennett, Arch Intern Med 2005 165 68 74
16. Impact of inappropriate drug use among hospitalized older adults. G Onder F Landi R Liperoti D Fialova G Gambassi R Bernabei, Eur J Clin Pharmacol 2005 61 453 459
17. The risk of adverse drug events and hospital-related morbidity and mortality among older adults with potentially inappropriate medication use. RL Page JM Ruscin, Am J Geriatr Pharmacother 2006 4 297 305
18. Medication use and falls in community-dwelling older persons. KD Kelly W Pickett N Yiannakoulias, Age Ageing 2003 32 503 509
19. Association between falls in elderly women and chronic diseases and drug use: cross sectional study. DA Lawlor R Patel S Ebrahim, BMJ 2003 327 712 717
20. Drugs and falls in older people: a systematic review and meta-analysis: II. Cardiac and analgesic drugs. RM Leipzig RG Cumming ME Tinetti, J Am Geriatr Soc 1999 47 40 50
21. Drugs and falls in older people: a systematic review and meta-analysis: I. Psychotropic drugs. RM Leipzig RG Cumming ME Tinetti, J Am Geriatr Soc 1999 47 30 39
22. Psychotropic drug use and the risk of hip fracture. WA Ray MR Griffin W Schaffner DK Baugh LJ Melton III, N Engl J Med 1987 316 363 369
23. Benzodiazepines of long and short elimination half-life and the risk of hip fracture. WA Ray MR Griffin W Downey, JAMA 1989 262 3303 3307
24. A 5-year prospective assessment of the risk associated with individual benzodiazepines and doses in new elderly users. R Tamblyn M Abrahamowicz R du Berger P McLeod G Bartlett, J Am Geriatr Soc 2005 53 233 241
25. Risk factors for falls among elderly persons living in the community. ME Tinetti M Speechley SF Ginter, N Engl J Med 1988 319 1701 1707
26. Guideline for the prevention of falls in older persons. American Geriatrics Society, British Geriatrics Society, and American Academy of Orthopaedic Surgeons Panel on Falls Prevention, J Am Geriatr Soc 2001 49 664 672
27. Vascular factors and risk of dementia: design of the Three-City Study and baseline characteristics of the study population. Neuroepidemiology 2003 22 316 325
28. Relationship between body mass index and different domains of disability in older persons: the 3C study. S Larrieu K Peres L Letenneur, Int J Obes Relat Metab Disord 2004 28 1555 1560
29. A Guttman health scale for the aged. I Rosow N Breslau, J Gerontol 1966 21 556 559
30. Collaborating Centre for Drug Statistics Methodology Guidelines for ATC Classification and DDD assignment. WHO, WHO, Geneva 1996
31. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. DM Fick JW Cooper WE Wade JL Waller JR Maclean MH Beers, Arch Intern Med 2003 163 2716 2724
32. Potentially inappropriate medications in the elderly: a French consensus panel list. ML Laroche JP Charmes L Merle, Eur J Clin Pharmacol 2007 63 725 731
33. Psychotropic medications and risk for falls among community-dwelling frail older people: an observational study. F Landi G Onder M Cesari C Barillaro A Russo R Bernabei, J Gerontol A Biol Sci Med Sci 2005 60 622 626
34. Association between falls in elderly women and chronic diseases and drug use: cross sectional study. DA Lawlor R Patel S Ebrahim, BMJ 2003 327 712 717
35. Drugs and falls in older people: a systematic review and meta-analysis: I. Psychotropic drugs. RM Leipzig RG Cumming ME Tinetti, J Am Geriatr Soc 1999 47 30 39
36. Benzodiazepines and injurious falls in community dwelling elders. A Pariente JF Dartigues J Benichou L Letenneur N Moore A Fourrier-Reglat, Drugs Aging 2008 25 61 70
37. Drugs and falls in older people: a systematic review and meta-analysis: I. Psychotropic drugs. RM Leipzig RG Cumming ME Tinetti, J Am Geriatr Soc 1999 47 30 39
38. Psychotropic medications and risk for falls among community-dwelling frail older people: an observational study. F Landi G Onder M Cesari C Barillaro A Russo R Bernabei, J Gerontol A Biol Sci Med Sci 2005 60 622 626 15972615
39. A 5-year prospective assessment of the risk associated with individual benzodiazepines and doses in new elderly users. R Tamblyn M Abrahamowicz R du Berger P McLeod G Bartlett, J Am Geriatr Soc 2005 53 233 241
40. Inappropriate prescribing for elderly Americans in a large outpatient population. LH Curtis T Ostbye V Sendersky, Arch Intern Med 2004 164 1621 1625
41. Trends in the prescription of inappropriate drugs for the elderly between 1995 and 1999. B Stuart S Kamal-Bahl B Briesacher, Am J Geriatr Pharmacother 2003 1 61 74
42. Potentially inappropriate medication use in the community-dwelling elderly: findings from the 1996 Medical Expenditure Panel Survey. C Zhan J Sangl AS Bierman, JAMA 2001 286 2823 2829
43. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. DM Fick JW Cooper WE Wade JL Waller JR Maclean MH Beers, Arch Intern Med 2003 163 2716 2724
44. The French Drug Database Thériaque. 2008 http://www.theriaque.org
45. Psychotropic medication withdrawal and a home-based exercise program to prevent falls: a randomized, controlled trial. AJ Campbell MC Robertson MM Gardner RN Norton DM Buchner, J Am Geriatr Soc 1999 47 850 853
46. Améliorer la prescription des psychotropes chez les personnes gées. Haute Autorité de Santé 2007 http://www.has-sante.fr
47. Benzodiazepine use in an elderly community-dwelling population. Characteristics of users and factors associated with subsequent use. A Fourrier L Letenneur JF Dartigues N Moore B Bégaud, Eur J Clin Pharmacol 2001 57 419 425
48. Progressive trends in the prevalence of benzodiazepine prescribing in older people in Ontario, Canada. K Tu MM Mamdani JE Hux JB Tu, J Am Geriatr Soc 2001 49 1341 1345
49. New evidence on benzodiazepine use and falls: the time factor. CI Neutel JP Hirdes CJ Maxwell SB Patten, Age Ageing 1996 25 273 278