The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis

Pharmacological Research

Volumn 87, Issue , 2014, Pages 151-159

  Navarria, Andrea ^a   Tamburella, Alessandra ^a   Iannotti, Fabio A ^b   Micale, Vincenzo ^a,c   Camillieri, Giovanni ^a   Gozzo, Lucia ^a   Verde, Roberta ^b   Imperatore, Roberta ^b   Leggio, Gian Marco ^a   Drago, Filippo ^a   Di Marzo, Vincenzo ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b CNR   (Italy)

^c MASARYK UNIVERSITY   (Czech Republic)

Author keywords

FAAH; HPA axis; N Arachidonoylserotonin; Stress; TRPV1

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ANANDAMIDE; BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; FATTY ACID AMIDASE; FATTY ACID AMIDASE INHIBITOR; N ARACHIDONOYLSEROTONIN; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST; 2-ARACHIDONYLGLYCEROL; ACYLGLYCEROL; AMIDASE; AMIDE; ARACHIDONIC ACID DERIVATIVE; ARACHIDONOYLSEROTONIN; ENDOCANNABINOID; FATTY-ACID AMIDE HYDROLASE; SEROTONIN; TRPV1 PROTEIN, RAT; VANILLOID RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; FORCED SWIM TEST; HIPPOCAMPUS; HOPELESSNESS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMOBILIZATION STRESS; MALE; MEDIAL PREFRONTAL CORTEX; NEUROPHARMACOLOGY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TASK PERFORMANCE; TREATMENT RESPONSE; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; BRAIN; DRUG EFFECTS; DRUG THERAPY; EXERCISE; GENETICS; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MENTAL STRESS; METABOLISM; SWIMMING; WISTAR RAT;

AMIDOHYDROLASES; ANIMALS; ARACHIDONIC ACIDS; BEHAVIOR, ANIMAL; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; ENDOCANNABINOIDS; GLYCERIDES; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; PITUITARY-ADRENAL SYSTEM; POLYUNSATURATED ALKAMIDES; RATS; RATS, WISTAR; RESTRAINT, PHYSICAL; SEROTONIN; STRESS, PSYCHOLOGICAL; SWIMMING; TRPV CATION CHANNELS;

EID: 84907356119     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2014.04.014     Document Type: Article

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