Anticonvulsant effects of acute treatment with cyane-carvone at repeated oral doses in epilepsy models

Pharmacology Biochemistry and Behavior

Volumn 124, Issue , 2014, Pages 421-424

  Marques, Thiago Henrique Costa ^a   Marques, Maria Leonildes Boavista Gomes Castelo Branco ^a   Medeiros, Jand Venes Rolim ^a   Lima, Tamires Cardoso ^b   De Sousa, Damião Pergentino ^c   De Freitas, Rivelilson Mendes ^a  

^a FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

^b FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

^c FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

Author keywords

Anticonvulsant; Cyane carvone; Mice; Seizures; Terpene

Indexed keywords

ANTICONVULSIVE AGENT; CARVONE; CYANE CARVONE; DIAZEPAM; FLUMAZENIL; PENTETRAZOLE; PICROTOXIN; PILOCARPINE; UNCLASSIFIED DRUG; 5-ISOPROPENYL-2-METHYL-3-OXOCYCLOHEXANOCARBONITRILE; NITRILE; TERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EPILEPSY; LATENT PERIOD; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPEATED DRUG DOSE; SEIZURE; ANIMAL; DISEASE MODEL; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ANIMALS; ANTICONVULSANTS; DISEASE MODELS, ANIMAL; EPILEPSY; MALE; MICE; MONOTERPENES; NITRILES;

EID: 84907339392     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2014.06.016     Document Type: Article

References (25)

1. H. Blumenfeld New strategies for preventing epileptogenesis: perspective and overview Neurosci Lett 497 2011 153 154
2. E.N. Bum, M. Schmutz, C. Meyer, A. Rakotonirina, M. Bopelet, and C. Portet et al. Anticonvulsant properties of the methanolic extracts of Cypeus articulatus (Cyperaceae) J Ethnopharmacol 76 2001 145 150
3. G.C. Clark Isolation and identification of drugs 1st ed. 1978 William Clowes London 870
4. D.A. Costa, G.A. De Oliveira, T.C. Lima, P.S. Dos Santos, D.P. De Sousa, and R.M. De Freitas Anticonvulsant and antioxidant effects of cyano-carvone and its action on acetylcholinesterase activity in mice hippocampus Cell Mol Neurobiol 32 4 2012 633 640
5. D.A. Costa, G.A.L. Oliveira, J.P. Costa, G.F. Souza, D.P. De Sousa, and R.M. Freitas Evaluation of acute toxicity and anxiolytic effect of a synthetic derivative of carvone Rev Bras Ciênc Saúde 16 2012 303 310
6. D.A. Costa, G.A.L. Oliveira, D.P. Sousa, and R.M. Freitas Avaliação do potencial antioxidante in vitro do composto ciano-carvona Rev Ciênc Farm Básica Apl 33 4 2012 567 575
7. D.P. De Sousa, F.F.F. Nóbrega, and R.N. De Almeida Influence of the chirality of (R)-(-)- and (S)-(+)-carvone in the central nervous system: a comparative study Chirality 19 2007 264 268
8. D.P. De Sousa, E. Raphael, and T.J. Brocksom Synthesis of (R)-(-)-carvone derivatives Z Naturforsch 65 2010 1381 1383
9. R.M. Freitas The evaluation of effects of lipoic acid on the lipid peroxidation, nitrite formation and antioxidant enzymes in the hippocampus of rats after pilocarpine-induced seizures Neurosci Lett 455 2009 140 144
10. J.C.R. Gonçalves, A.M.H. Alves, A.E.V. Araújo, J.S. Cruz, and D.A.M. Araújo Distinct effects of carvone analogues on the isolated nerve of rats Eur J Pharmacol 645 1 2010 108 112
11. V.Y. Hatano, A.S. Torricelli, A.C.C. Giassi, L.A. Coslope, and M.B. Viana Anxiolytic effects of repeated treatment with an essential oil from Lippia alba and (R)-(-)-carvone in the elevated T-maze Braz J Med Biol Res 45 3 2012 238 243
12. M. Kesim, E. Yulug, M. Kadioglu, I. Erkoseoglu, D.A. Aykan, and N.I. Kalyoncu et al. The effect of simvastatin on picrotoxin-induced seizure in mice JPMA J. Pak. Med. Assoc. 62 2012 1187 1191
13. B. Lasztoczi, G. Nyitrai, L. Heja, and J. Kardos Synchronization of GABAergic inputs to CA3 pyramidal cells precedes seizure like event onset in juvenile rat hippocampal slices J Neurophysiol 102 2009 2538 2553
14. J. Lehmann, A. Hutchison, S.E. McPherson, C. Mondadori, M. Schmutz, and C.M. Sinton et al. CGS 19755 a selective and competitive N-methyl-D-aspartate- type excitatory amino acid receptor antagonist J Pharmacol Exp Ther 246 1988 65 75
15. M. Li, R. Kang, J. Shi, G. Liu, and J. Zhang Anticonvulsant activity of B2, an adenosine analog, on chemical convulsant-induced seizures PLoS One 8 6 2013 1 10
16. J.A. Loeb Identifying targets for preventing epilepsy using systems biology Neurosci Lett 497 2011 205 212
17. M.W. Lopes, F.M.S. Soares, N. De Mello, J.C. Nunes, A.G. Cajado, and D. De Brito et al. Time-dependent modulation of AMPA receptor phosphorylation and mRNA expression of NMDA receptors and glial glutamate transporters in the rat hippocampus and cerebral cortex in a pilocarpine model of epilepsy Exp Brain Res 226 2 2013 153 163
18. A.K. Njamnshi, A.C.Z.K. Bissek, F.N. Yepnjio, E.N. Tabah, S.A. Angwafor, and C.T. Kuate et al. A community survey of knowledge, perceptions, and practice with respect to epilepsy among traditional healers in the Batibo Health District, Cameroon Epilepsy Behav 17 2010 95 102
19. T.C. Okoye, P.A. Akah, E.O. Omeje, F.B.C. Okoye, and C.S. Nworu Anticonvulsant effect of kaurenoic acid isolated from the root bark of Annona senegalensis Pharmacol Biochem Behav 109 2013 38 43
20. S.F. Ramos, B.P. Mendonça, D.D. Leffa, R. Pacheco, A.P. Damiani, and G. Hainzenreder et al. Effects of neuropeptide S on seizures and oxidative damage induced by pentylenetetrazole in mice Pharmacol Biochem Behav 103 2012 197 203
21. L. Saxona, S. Borga, and A.J. Hiltunenb Reduction of aggression during benzodiazepine withdrawal: effects of flumazenil Pharmacol Biochem Behav 96 2010 148 151
22. M. Smith, K.S. Wilcox, and H.S. White Discovery of antiepileptic drugs Neurotherapeutics 4 2007 12 17
23. F.V. Souza, M.B. da Rocha, D.P. de Souza, and R.M. Marçal (-)-Carvone: antispasmodic effect and mode of action Fitoterapia 85 2013 20 24
24. P.C.P. Telles Filho, A.R. Chagas, M.L.P. Pinheiro, A.M.J. Lima, and M.A.S. Durão Utilização de benzodiazepínicos por idosos de uma estratégia de saúde da família: implicações para enfermagem Esc Anna Ner 15 3 2011 581 586
25. W.A. Turski, E.A. Cavalheiro, M. Schwarz, S.J. Czuczwar, Z. Kleinrok, and L. Turski Limbic seizures produced by pilocarpine in rats: a behavioural, electroencephalographic and neuropathological study Behav Brain Res 9 1983 315 335