Carvone: Antispasmodic effect and mode of action

Fitoterapia

Volumn 85, Issue 1, 2013, Pages 20-24

  Souza, Fábia Valéria M ^a   Da Rocha, Marcelly Barbosa ^a   De Souza, Damião P ^a   Marçal, Rosilene Moretti ^a  

^a FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

Author keywords

( ) Carvone; Antispasmodic; Calcium channel blocker

Indexed keywords

CALCIUM ION; CARBACHOL; CARVONE; HISTAMINE; MORPHINE; POTASSIUM ION; SPASMOLYTIC AGENT; VERAPAMIL;

ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; FEMALE; IC 50; ILEUM CONTRACTION; INTESTINAL SPASM; INTESTINE MUSCLE; MALE; NONHUMAN; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION;

ANIMALS; BARIUM COMPOUNDS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CARBACHOL; CHLORIDES; DRUG EVALUATION, PRECLINICAL; FEMALE; GUINEA PIGS; HISTAMINE; ILEUM; MALE; MENTHA SPICATA; MONOTERPENES; MUSCLE, SMOOTH; PARASYMPATHOLYTICS; POTASSIUM CHANNELS; POTASSIUM CHLORIDE; VERAPAMIL;

EID: 84874709281     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2012.10.012     Document Type: Article

References (15)

1. M. Lahlou Essential oils and fragrance compounds: bioactivity and mechanisms of action Flavour Fragrance J 19 2004 159
2. G. Buchbauer, W. Jäger, A. Gruber, and H. Dietrich R-(+)- and S-(-)-carvone: influence of chirality on locomotion activity in mice Flavour Fragrance J. 20 2005 686
3. D.P. de Sousa, F.F. de Farias Nóbrega, and R.N. de Almeida Influence of the chirality of (R)-(-)- and (S)-(+)-carvone in the central nervous system: a comparative study Chirality 19 2007 264
4. E. Heuberger, T. Hongratanaworakit, C. Bohm, R. Weber, and G. Buchbauer Effects of chiral fragrances on human autonomic nervous system parameters and self-evaluation Chem Senses 26 2001 281
5. D.P. de Sousa, G.A. Júnior, L.N. Andrade, F.R. Calasans, X.P. Nunes, and J.M. Barbosa-Filho Structure and spasmolytic activity relationships of monoterpene analogues found in many aromatic plants Z Naturforsch 63 2008 808
6. G. Edwards, M. Henshaw, M. Miller, and A.H. Weston Comparison of the effects of several potassium-channel openers on rat bladder and rat portal vein in vitro Br J Pharmacol 102 1991 679
7. S.V.F. Madeira, F.J.A. Matos, J.H. Leal-Cardoso, and D.N. Criddle Relaxant effects of the essential oil of Ocimum gratissimum on isolated ileum of the guinea pig J Ethnopharmacol 81 2002 1
8. H. Karaki, H. Ozaki, M. Hori, M. Mitsui-Saito, K. Amano, and K. Harada Calcium movements, distribution, and functions in smooth muscle Pharmacol Rev 49 1997 157
9. K. Lawson, and I. Cavero Effects of Ca2 + antagonists and K +-channel activators on K +-induced contractions in the rat aorta J Auton Pharmacol 9 1989 329
10. W.D. Paton The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum Br J Pharmacol Chemother 12 1957 119
11. European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes. European Treaty Series, Strasbourg, ETS-123 http://conventions.coe.int/Treaty/en/Treaties/html/123.htm/ [30 May 2012]
12. A.C. Carvalho, D.S. Almeida, M.G. Melo, S.C. Cavalcanti, and R.M. Marçal Evidence of the mechanism of action of Erythrina velutina Willd (Fabaceae) leaves aqueous extract J Ethnopharmacol 122 2009 374
13. J.C. Gonçalves, F. de S. Oliveira, R.B. Benedito, D.P. de Sousa, R.N. de Almeida, and D.A. de Araújo Antinociceptive activity of (-)-carvone: evidence of association with decreased peripheral nerve excitability Biol Pharm Bull 31 2008 1017
14. H. Gurdal, Y. Sara, and F.C. Tulunay Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats Pharmacology 44 1992 290
15. H.F. Miranda, D. Bustamante, V. Kramer, T. Pelissier, H. Saavedra, and C. Paeile Antinociceptive effects of Ca2 + channel blockers Eur J Pharmacol 217 1992 137