EPA's SHEDS-multimedia model: Children's cumulative pyrethroid exposure estimates and evaluation against NHANES biomarker data

Environment International

Volumn 73, Issue , 2014, Pages 304-311

  Xue, Jianping ^a   Zartarian, Valerie ^a   Tornero Velez, Rogelio ^a   Tulve, Nicolle S ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Cumulative; Dose; Exposure; Model; Pyrethroids; SHEDS Multimedia

Indexed keywords

HOUSING; MODELS; PESTICIDES;

CUMULATIVE; DOSE; EXPOSURE; PYRETHROIDS; SHEDS-MULTIMEDIA;

LOADING;

CYFLUTHRIN; CYPERMETHRIN; PERMETHRIN; PYRETHROID; BIOLOGICAL MARKER; PESTICIDE;

BIOMARKER; CHILD HEALTH; CYPERMETHRIN; METABOLITE; PERMETHRIN; PYRETHROID;

ADULT; AGE DISTRIBUTION; ARTICLE; CHILD; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DATA BASE; DIETARY INTAKE; ENVIRONMENTAL EXPOSURE; EPA SHEDS MULTIMEDIA MODEL; EVALUATION STUDY; HOUSEHOLD; HUMAN; INFORMATION STORAGE; MODEL; MULTIMEDIA; PESTICIDE SPRAYING; POPULATION RESEARCH; PRESCHOOL CHILD; PRIORITY JOURNAL; RESIDENTIAL AREA; RISK ASSESSMENT; SKIN ABSORPTION; BIOLOGICAL MODEL; FEMALE; MALE; NUTRITION;

ADULT; BIOLOGICAL MARKERS; CHILD, PRESCHOOL; ENVIRONMENTAL EXPOSURE; FEMALE; HUMANS; MALE; MODELS, BIOLOGICAL; MULTIMEDIA; NUTRITION SURVEYS; PESTICIDES; PYRETHRINS;

EID: 84907332003     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2014.08.008     Document Type: Article

References (31)

1. Barr D.B., Olsson A.O., Wong L.Y., Udunka S., Baker S.E., Whitehead R.D., et al. Urinary concentrations of metabolites of pyrethroid insecticides in the general U.S. population: National Health and Nutrition Examination Survey 1999-2002. Environ Health Perspect 2010, 118(6):742-748.
2. Eadsforth C.V., Bragt P.C., van Sittert N.J. Human dose-excretion studies with pyrethroid insecticides cypermethrin and alpha-cypermethrin: relevance for biological monitoring. Xenobiotica 1988, 18:603-614.
3. EPA OPP Pyrethrins/pyrethroid cumulative risk assessment http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPP-2011-0746-0003.
4. FIFRA SAP A set of scientific issues being considered by the environmental protection agency regarding: review of EPA/ORD/NERL's SHEDS-multimedia model aggregate version 3, SAP Minutes No. 2007-06. August 14-15, 2007 FIFRA Scientific Advisory Panel Meeting, Arlington, VA 2007, [http://www.epa.gov/scipoly/sap/meetings/2007/081407_mtg.htm].
5. FIFRA SAP A set of scientific issues being considered by the environmental protection agency regarding: SHEDS-multimedia version 4, peer consult on PBPK modeling, and a SHEDS-PBPK permethrin study. SAP Minutes No. 2010-06. July 20-22, 2010. FIFRA Scientific Advisory Panel Meeting, Arlington, VA 2010, [http://www.epa.gov/scipoly/sap/meetings/2010/july/072010minutes.pdf; http://www.regulations.gov/#!docketDetail;D=EPA-HQ-OPP-2010-0383].
6. Glen G., Smith L., Isaacs K., Mccurdy T., Langstaff J. A new method of longitudinal diary assembly for human exposure modeling. J Expo Sci Environ Epidemiol 2008, 18:299-311.
7. Glen G., Zartarian V.G., Smith L., Xue J. The stochastic human exposure and dose simulation model for multimedia, multipathway chemicals (SHEDS-multimedia): residential module. Draft technical manual, June 16, 2010 2010, U.S. Environmental Protection Agency, [http://www.epa.gov/heasd/products/sheds_multimedia/files/SHEDS_Residentialv4_Techmanual_06-16-2010.Final.pdf].
8. Heudorf U., Angerer J. Metabolites of pyrethroid insecticides in urine specimens: current exposure in an urban population in Germany. Environ Health Perspect 2001, 109:213-217.
9. Isaacs K., Stallings C., Zartarian V.G., Glen G. Stochastic human exposure and dose simulation (SHEDS) model for multimedia, multipathway chemicals: version 4 residential module. user guide. Prepared for the July 20-22, 2010 EPA FIFRA SAP, Crystal City, VA 2010.
10. Isaacs K., Xue J., Stallings C., Zartarian V.G. Stochastic human exposure and dose simulation (SHEDS) model for multimedia, multipathway chemicals: version 1 SHEDS-dietary module user guide. Prepared for the July 20-22, 2010 EPA FIFRA SAP, Crystal City, VA 2010.
11. Jacobs L., Driver J., Pandian M., Jacobs L., Driver J., Pandian M. Residential exposure joint venture: national pesticide use survey - design, implementation, analysis methods and results: Lab Project Number: 03-REJV-4M-001: 030-REJV-4M-001: 8D 2003, Unpublished study prepared by, NFO WorldGroup and infoscientific.com, Inc., [8515 p., cited in EPA MRID 45870701, March 3].
12. Kissel J.C. The mismeasure of dermal absorption. J Expo Sci Environ Epidemiol 2011, 21:302-309.
13. Lu C., Barr D.B., Pearson M., Bartell S., Bravo R. A longitudinal approach to assessing urban and suburban children's exposure to pyrethroid pesticides. Environ Health Perspect 2006, 114(9):1419-1423.
14. Morgan M.K., Sheldon L.S., Croghan C.W., Jones P.A., Robertson G.L., Chuang J.C., et al. Exposures of preschool children to chlorpyrifos and its degradation product 3,5,6-trichloro-2-pyridinol in their everyday environments. J Expo Anal Environ Epidemiol 2005, 15(4):297-309.
15. Morgan M.K., Sheldon L.S., Croghan C.W., Jones P.A., Chuang J.C., Wilson N.K. An observational study of 127 preschool children at their homes and daycare centers in Ohio: environmental pathways to cis- and trans-permethrin exposure. Environ Res 2007, 104(2):266-274.
16. Nishi K., Huang H., Kamita S.G., Kim I.H., Morisseau C., Hammock B.D. Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2. Arch Biochem Biophys 2006, 445:115-123.
17. Shafer T., Meyer D., Crofton K. Developmental neurotoxicity of pyrethroid insecticides: critical review and future research needs. Environ Health Perspect 2005, 113:123-136.
18. Tomalik-Scharte D., Lazar A., Meins J., Bastian B., Ihrig M., Wachall B., et al. Dermal absorption of permethrin following topical administration. Eur J Clin Pharmacol 2005, 61:399-404.
19. Tulve N.S., Egeghy P.P., Fortmann R.C., Xue J., Evans J., Whitaker D.A., et al. Methodologies for estimating cumulative human exposures to current-use pyrethroid pesticides. J Expo Sci Environ Epidemiol 2011, 21(3):317-327.
20. U.S.EPA Exposure factors handbook 1997, U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Washington, DC, [August].
21. U.S.EPA Guidance on selecting age groups for monitoring and assessing childhood exposures to environmental contaminants. Risk assessment forum, EPA/630/P-03/003F 2005, NCEA, Washington, DC.
22. U.S.EPA Child-specific exposure factors handbook 2008, U.S. Environmental Protection Agency, Washington, D.C, [EPA/600/R-06/096F].
23. U.S.EPA Standard operating procedures for residential pesticide exposure assessment 2012, Health Effects Division, Office of Pesticide Programs, Office of Chemical Safety and Pollution Prevention, U.S. Environmental Protection Agency, Washington, DC, [October, http://www.epa.gov/pesticides/science/residential-exposure-sop.html].
24. Woollen B.H., Marsh J.R., Laird W.J.D., Lesser J.E. The metabolism of cypermethrin in man: differences on urinary metabolite profiles following oral and dermal administration. Xenobiotica 1992, 22:983-991.
25. Xue J., Zartarian V., Ozkaynak H., Dang W., Glen G., Smith L., et al. A probabilistic arsenic exposure assessment for children who contact CCA-treated playsets and decks, part 2: sensitivity and uncertainty analyses. Risk Anal 2006, 26(2):533-541.
26. Xue J., Zartarian V., Wang S.-W., Liu S.V., Georgopolous P. Probabilistic modeling of dietary arsenic exposure and dose and evaluation with 2003-2004 NHANES data. Environ Health Perspect 2010, 118(3):345-350.
27. Xue J., Zartarian V.G., Nako S. The stochastic human exposure and dose simulation (SHEDS)-dietary model technical manual. Prepared for the July 20-22, 2010 EPA FIFRA SAP, Crystal City, VA 2010, [http://www.epa.gov/heasd/documents/SHEDSDietary_TechManual_2012.pdf].
28. Xue J., Zartarian V.G., Liu S.V., Geller A. Methyl mercury exposure from fish consumption in vulnerable racial/ethnic populations: probabilistic SHEDS-dietary model analyses using 1999-2006 NHANES and 1990-2002 TDS data. Sci Total Environ 2012, 414(1):373-379.
29. Zartarian V., Xue J., Özkaynak H., Dang W., Glen G., Smith L., et al. A probabilistic arsenic exposure assessment for children who contact chromated copper arsenate (CCA)-treated playsets and decks, part 1: model methodology, variability results, and model evaluation. Risk Anal 2006, 26(2):515-531.
30. Zartarian V.G., Glen G., Smith L., Xue J. SHEDS-Multimedia model version 3 technical manual 2008, U.S. Environmental Protection Agency, [EPA/600/R-08/118].
31. Zartarian V.G., Xue J., Glen G., Smith L., Tulve N.S., Tornero-Velez R. Quantifying children's aggregate (dietary and residential) exposure and dose to permethrin: application and evaluation of EPA's probabilistic SHED-Multimedia model. J Expo Sci Environ Epidemiol 2012, 22(3):267-273.