Relationship between early postoperative C-reactive protein elevation and long-term postoperative major adverse cardiovascular and cerebral events in patients undergoing off-pump coronary artery bypass graft surgery: A retrospective study

British Journal of Anaesthesia

Volumn 113, Issue 3, 2014, Pages 391-401

  Min, J J ^a,e   Nam, K ^a   Kim, T K ^a   Kim, H J ^c   Seo, J H ^a   Hwang, H Y ^b   Kim, K B ^b   Murkin, J M ^d   Hong, D M ^a   Jeon, Y ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

^d WESTERN UNIVERSITY   (Canada)

^e Samsung Medical Center   (South Korea)

Author keywords

C reactive protein; Complication; Off pump coronary artery bypass; Outcomes assessment; Postoperative

Indexed keywords

C REACTIVE PROTEIN; TROPONIN I; BIOLOGICAL MARKER;

ADULT; AGED; ALKALOSIS; ARTICLE; BODY TEMPERATURE; CEREBROVASCULAR ACCIDENT; ELECTRONIC MEDICAL RECORD; ERYTHROCYTE TRANSFUSION; FEMALE; FOLLOW UP; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HEART RATE; HUMAN; LONG TERM CARE; MAJOR ADVERSE CARDIOVASCULAR AND CEREBRAL EVENT; MAJOR CLINICAL STUDY; MALE; OFF PUMP CORONARY SURGERY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; BLOOD; CARDIOVASCULAR DISEASES; CEREBROVASCULAR DISORDERS; INFLAMMATION; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PROPORTIONAL HAZARDS MODEL; TREATMENT OUTCOME; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; CEREBROVASCULAR DISORDERS; CORONARY ARTERY BYPASS, OFF-PUMP; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFLAMMATION; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; POSTOPERATIVE PERIOD; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84907325663     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aeu099     Document Type: Article

References (30)

1. Libby P. Inflammation in atherosclerosis. Nature 2002;420: 868-74
2. Libby P, Theroux P. Pathophysiology of coronary artery disease. Circulation 2005; 111: 3481-8
3. Chalela JA. Evaluating the carotid plaque: going beyond stenosis. Cerebrovasc Dis 2009; 27: 19-24
4. Elkind MS. Inflammatory markers and stroke. Curr Cardiol Rep 2009; 11: 12-20
5. Parolari A, Camera M, Alamanni F, et al. Systemicinflammationafter on-pump and off-pump coronary bypass surgery: a one-month follow-up. Ann Thorac Surg 2007; 84: 823-8
6. Tomic V, Russwurm S, Moller E, et al. Transcriptomic and proteomic patterns of systemic inflammation in on-pump and off-pump coronary artery bypass grafting. Circulation 2005; 112: 2912-20
7. Ridker PM, Rifai N, Rose L, Buring JE, Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 2002; 347: 1557-65
8. Perry TE, Muehlschlegel JD, Liu KY, et al. Preoperative C-reactive protein predicts long-term mortality and hospital length of stay after primary, nonemergent coronary artery bypass grafting. Anesthesiology 2010; 112: 607-13
9. Padayachee L, Rodseth RN, Biccard BM. A meta-analysis of the utility of C-reactive protein in predicting early, intermediate-term and long term mortalityand majoradverse cardiac events in vascular surgical patients. Anaesthesia 2009; 64: 416-24
10. Choi JH, Cho DK, Song YB, et al. Preoperative NT-proBNP and CRP predict perioperative major cardiovascular events in non-cardiac surgery. Heart 2010; 96: 56-62
11. Gomma AH, Hirschfield GM, Gallimore JR Jr, Lowe GD, Pepys MB, Fox KM. Preproceduralinflammatory markersdo not predict restenosis after successful coronary stenting. Am Heart J 2004; 147: 1071-7
12. Cole DS, Watts A, Scott-Coombes D, Avades T. Clinical utility of perioperative C-reactive protein testing in general surgery. Ann R Coll Surg Engl 2008; 90: 317-21
13. van Genderen ME, Lima A, de Geus H, et al. Serum C-reactive protein as a predictor of morbidity and mortality in intensive care unit patients after esophagectomy. Ann Thorac Surg 2011; 91: 1775-9
14. Kangasniemi O-P, Biancari F, Luukkonen J, et al. Preoperative C-reactive protein is predictive of long-term outcome after coronary artery bypass surgery. Eur J Cardiothorac Surg 2006; 29: 983-5
15. Yi G, Joo HC, Yoo KJ. Impact of preoperative C-reactive protein on midterm outcomes after off-pump coronaryartery bypass grafting. Thorac Cardiovascu Surg 2013; 61: 682-6
16. Li X, Liu XH, Nie SP, et al. Prognostic value of baseline C-reactive protein levels in patients undergoing coronary revascularization. Chin Med J 2010; 123: 1628-32
17. Kouvelos GN, Milionis HJ, Arnaoutoglou EM, et al. Postoperative levels of cardiac troponin versus CK-MB and high-sensitivity C-reactive proteinfor thepredictionof1-yearcardiovascularoutcomeinpatients undergoing vascular surgery. Coron Artery Dis 2011; 22: 428-34
18. Corral L, Carrio ML, Ventura JL, et al. Is C-reactive protein a biomarker for immediate clinical outcome after cardiac surgery? J Cardiothorac Vasc Anesth 2009; 23: 166-9
19. Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 2003; 107: 363-9
20. Alves RL, Aragao e Silva AL, Kraychete NC, Campos GO, Martins Mde J, Modolo NS. Intraoperative lactate levels and postoperative complications of pediatric cardiac surgery. Paediatr Anaesth 2012; 22: 812-7
21. Demers P, Elkouri S, Martineau R, Couturier A, Cartier R. Outcome with high blood lactate levels during cardiopulmonary bypass in adult cardiac operation. Ann Thorac Surg 2000; 70: 2082-6
22. Miyaji K, Miyamoto T, Kohira S, et al. The influences of red blood cell transfusion on perioperative inflammatory responses using a miniaturized biocompatible bypass with an asanguineous prime. Int Heart J 2009; 50: 581-9
23. Hod EA, Zhang N, Sokol SA, et al. Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation. Blood 2010; 115: 4284-92
24. Mangalmurti NS, Xiong Z, Hulver M, et al. Loss of red cell chemokine scavenging promotes transfusion-related lung inflammation. Blood 2009; 113: 1158-66
25. Steinvil A, Rogowski O, Banai S, et al. Anemia and inflammation have an additive value in risk stratification of patients undergoing coronary interventions. J Cardiovasc Med (Hagerstown) 2013, doi:10.2459/JCM. 0b013e32836380b4
26. Kulik A, Ruel M. Statins and coronary artery bypass graft surgery: preoperative and postoperative efficacy and safety. Expert Opin Drug Saf 2009; 8: 559-71
27. Knatterud GL, Rosenberg Y, Campeau L, et al. Long-term effects on clinical outcomes of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation in the post coronary artery bypass graft trial. Post CABG Investigators. Circulation 2000; 102: 157-65
28. White CW, Gobel FL, Campeau L, et al. Effect of an aggressive lipid-lowering strategy on progression of atherosclerosis in the left main coronary artery from patients in the post coronary artery bypass graft trial. Circulation 2001; 104: 2660-5
29. Kulik A, Brookhart MA, Levin R, Ruel M, Solomon DH, Choudhry NK. Impact of statin use on outcomes after coronary artery bypass graft surgery. Circulation 2008; 118: 1785-92
30. Gao Y, Jia ZM, Sun YJ, Zhang ZH, Ren LN, Qi GX. Effect of high-dose rosuvastatin loading before percutaneous coronary intervention in female patients with non-ST-segment elevation acute coronary syndrome. Chin Med J 2012; 125: 2250-4