Randomized trial comparing ferric carboxymaltose vs oral ferrous glycine sulphate for postoperative anaemia after total knee arthroplasty

British Journal of Anaesthesia

Volumn 113, Issue 3, 2014, Pages 402-409

  Bisbe, E ^a,b   Molto L ^a   Arroyo, R ^a   Muniesa, J M ^a   Tejero, M ^a  

^a HOSPITAL DE L ESPERANÇA   (Spain)

^b HOSPITAL DEL MAR   (Spain)

Author keywords

Anaemia; Ferric carboxymaltose; I.v. iron; Iron deficiency; Patient bloodmanagement; Surgery

Indexed keywords

ANTIANEMIC AGENT; FERRIC CARBOXYMALTOSE; FERROUS GLYCINE SULPHATE; HEMOGLOBIN; IRON; UNCLASSIFIED DRUG; FERRIC ION; FERROGLYCINE SULFATE; FERROUS ION; GLYCINE; MALTOSE;

ADULT; AGED; ALLERGIC REACTION; ANEMIA; ARTICLE; BLOOD TRANSFUSION; CAROLI DISEASE; CHOLANGITIS; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; FEMALE; FERRITIN BLOOD LEVEL; FOLLOW UP; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPERTRANSAMINASEMIA; HYPOTENSION; INTENTION TO TREAT ANALYSIS; IRON STORAGE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; OPERATIVE BLOOD LOSS; OUTCOME ASSESSMENT; PHYSICAL PERFORMANCE; POSTOPERATIVE ANEMIA; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SWELLING; TASK PERFORMANCE; TIBIA FRACTURE; TOTAL KNEE REPLACEMENT; URINARY TRACT INFECTION; WAKEFULNESS; WOUND COMPLICATION; ANALOGS AND DERIVATIVES; COMPARATIVE STUDY; KNEE ARTHROPLASTY; MIDDLE AGED; ORAL DRUG ADMINISTRATION; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDY; SINGLE BLIND PROCEDURE; SPAIN; TREATMENT OUTCOME; VERY ELDERLY;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; ANEMIA; ARTHROPLASTY, REPLACEMENT, KNEE; FEMALE; FERRIC COMPOUNDS; FERROUS COMPOUNDS; GLYCINE; HUMANS; MALE; MALTOSE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; SINGLE-BLIND METHOD; SPAIN; TREATMENT OUTCOME;

EID: 84907300088     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aeu092     Document Type: Article

References (40)

1. Saleh E, McClelland DB, Hay A, Semple D, Walsh TS. Prevalence of anaemia before major joint arthroplasty and the potential impact of preoperative investigation and correction on perioperative blood transfusions. Br J Anaesth 2007; 99: 801-8
2. Shander A, Knight K, Thurer R, Adamson J, Spence R. Prevalenceand outcomes of anemia in surgery: a systematic review of the literature. Am J Med 2004; 116(Suppl. 7A): 58-69S
3. Spahn DR. Anemia and patient blood management in hip and knee surgery: a systematic reviewof the literature. Anesthesiology 2010; 113: 482-95
4. Beattie WS, Karkouti K, Wijeysundera DN, Tait G. Risk associated with preoperative anemia in noncardiac surgery: a single-center cohort study. Anesthesiology 2009; 110: 574-81
5. Carson JL, Duff A, Berlin JA, et al. Perioperative blood transfusion and postoperative mortality. J Am Med Assoc 1998; 279: 199-205
6. Dunne JR, Malone D, Tracy JK, Gannon C, Napolitano LM. Perioperative anemia: an independent risk factor for infection, mortality, and resource utilization in surgery. J Surg Res 2002; 102: 237-44
7. Glance LG, Dick AW, Mukamel DB, et al. Association between intraoperative blood transfusionand mortalityand morbidity in patients undergoing noncardiac surgery. Anesthesiology 2011;114: 283-92
8. Musallam KM, Tamim HM, Richards T, et al. Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study. Lancet 2011; 378: 1396-407
9. Sabate S, Mases A, Guilera N, et al. Incidenceandpredictors ofmajor perioperative adverse cardiac and cerebrovascular events in noncardiac surgery. Br J Anaesth 2011; 107: 879-90
10. Wu WC, Schifftner TL, Henderson WG, et al. Preoperativehematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery. J Am Med Assoc 2007; 297: 2481-8
11. Goodnough LT, Shander A. Patient blood management. Anesthesiology 2012; 116: 1367-76
12. Kotze A, Carter LA, Scally AJ. Effect of a patient blood management programme on preoperative anaemia, transfusion rate, and outcome after primary hip or knee arthroplasty: a quality improvement cycle. Br J Anaesth 2012; 108: 943-52
13. Shander A, Van AH, Colomina MJ, et al. Patient blood management in Europe. Br J Anaesth 2012; 109: 55-68
14. Spahn DR, Moch H, Hofmann A, Isbister JP. Patient blood management: the pragmatic solution for the problems with blood transfusions. Anesthesiology 2008; 109: 951-3
15. Bisbe E, Molto L. Pillar2: minimising bleeding and blood loss. Best Pract Res Clin Anaesthesiol 2013; 27: 99-110
16. Vuille-Lessard E, Boudreault D, Girard F, Ruel M, Chagnon M, Hardy JF. Postoperative anemia does not impede functional outcome and quality of life early after hip and knee arthroplasties. Transfusion 2012; 52: 261-70
17. Robertsson O, Bizjajeva S, Fenstad AM, et al. Knee arthroplasty in Denmark, Norway and Sweden. Acta Orthop 2010; 81: 82-9
18. Singh JA, Vessely MB, Harmsen WS, et al. A population-based study of trends in the use of total hip and total knee arthroplasty, 1969-2008. Mayo Clin Proc 2010; 85: 898-904
19. Mont MA, Jacobs JJ. AAOS clinical practice guideline: preventing venous thromboembolic disease in patients undergoing elective hip and knee arthroplasty. J Am Acad Orthop Surg 2011; 19: 777-8
20. Lasocki S, Krauspe R, Mezzacasa A, von Heymann C, Spahn DR. Postoperative anaemia and the need for effective patient blood management (PBM) are major concerns in elective orthopaedic surgery-a multicentre observational study (PREPARE). Eur J Anaesthesiol 2012; 29: 97-8
21. van Iperen CE, Kraaijenhagen RJ, Biesma DH, Beguin Y, Marx JJ, van de Wiel A. Iron metabolism and erythropoiesis after surgery. Br J Surg 1998; 85: 41-5
22. Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005; 352: 1011-23
23. Gombotz H, Rehak PH, Shander A, Hofmann A. Blood use in elective surgery: the Austrian benchmark study. Transfusion 2007; 47: 1468-80
24. Bisbe E. Role of iron replacement in the management of preoperative anemia. Transfus Altern Transfus Med 2012; 12: 150-6
25. Goodnough LT, Maniatis A, Earnshaw P, et al. Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines. Br J Anaesth 2011; 106: 13-22
26. Leal-Noval SR, Muñoz M, Asuero M, et al. Spanish Consensus Statement on alternatives to allogeneic blood transfusion: the 2013 update of the "SevilleDocument". Blood Transfus 2013; 11: 585-610
27. Beris P, Munoz M, Garcia-Erce JA, Thomas D, Maniatis A, Van der Linden P. Perioperative anaemia management: consensus statement on the role of intravenous iron. Br J Anaesth 2008; 100: 599-604
28. Munoz M, Breymann C, Garcia-Erce JA, Gomez-Ramirez S, Comin J, Bisbe E. Efficacy and safety of intravenous iron therapy as an alternative/ adjunct to allogeneic blood transfusion. Vox Sang 2008; 94: 172-83
29. Mundy GM, Birtwistle SJ, Power RA. The effect of iron supplementation on the level of haemoglobin after lower limb arthroplasty. J Bone Joint Surg Br 2005; 87: 213-7
30. Lachance K, Savoie M, Bernard M, et al. Oral ferrous sulfate does not increase preoperative hemoglobin in patients scheduled for hip or knee arthroplasty. Ann Pharmacother 2011; 45: 764-70
31. Anker SD, Comin CJ, Filippatos G, et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med 2009; 361: 2436-48
32. Munoz M, Naveira E, Seara J, Cordero J. Effects of postoperative intravenous iron on transfusion requirements after lower limb arthroplasty. Br J Anaesth 2012; 108: 532-4
33. Bisbe E, Garcia-Erce JA, Diez-Lobo AI, Munoz M. A multicentre comparativestudyonthe efficacyof intravenousferric carboxymaltose and iron sucrose for correcting preoperative anaemia in patients undergoing major elective surgery. Br J Anaesth 2011; 107: 477-8
34. Streja E, Kovesdy CP, Greenland S, et al. Erythropoietin, iron depletion, and relative thrombocytosis: a possible explanation for hemoglobin-survival paradox in hemodialysis. Am J Kidney Dis 2008; 52: 727-36
35. Kulnigg-Dabsch S, Evstatiev R, Dejaco C, Gasche C. Effect of iron therapy on platelet counts in patients with inflammatory bowel disease-associated anemia. PLoS One 2012; 7: e34520
36. Henry DH, Dahl NV, Auerbach MA. Thrombocytosis and venous thromboembolism in cancer patients with chemotherapy induced anemia may be related to ESA induced iron restricted erythropoiesis and reversed by administration of IV iron. Am J Hematol 2012; 87: 308-10
37. Cuenca J, Garcia-Erce JA, Martinez F, Perez-Serrano L, Herrera A, Munoz M. Perioperative intravenous iron, with or without erythropoietin, plus restrictive transfusion protocol reduce the need for allogeneic blood after knee replacement surgery. Transfusion 2006; 46: 1112-9
38. Serrano-Trenas JA, Ugalde PF, Cabello LM, Chofles LC, Lazaro PS, Benitez PC. Role of perioperative intravenous iron therapy in elderly hip fracture patients: a single-center randomized controlled trial. Transfusion 2011; 51: 97-104
39. Bailie GR, Horl WH, Verhof JJ. Differences in spontaneously reported hypersensitivity and serious adverse events for intravenous iron preparations: comparison of Europe and North America. Drug Res 2011; 61: 267-75
40. Chertow GM, Mason PD, Vaage-Nilsen O, Ahlmen J. Update on adverse drug events associated with parenteral iron. Nephrol Dial Transplant 2006; 21: 378-82