Outcomes of a nurse-managed service for stable HIV-positive patients in a large South African public sector antiretroviral therapy programme

Tropical Medicine and International Health

Volumn 19, Issue 9, 2014, Pages 1029-1039

  Grimsrud, Anna ^a   Kaplan, Richard ^a   Bekker, Linda Gail ^a   Myer, Landon ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Antiretroviral therapy (highly active); Decentralization; Loss to follow up; Programme outcomes; Retention; Task shifting

Indexed keywords

ANTIRETROVIRUS AGENT; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

DECENTRALIZATION; HEALTH RISK; HUMAN IMMUNODEFICIENCY VIRUS; MORTALITY RISK; PUBLIC HEALTH;

ADULT; ARTICLE; COHORT ANALYSIS; FEMALE; FOLLOW UP; HEALTH SERVICE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; NURSE MANAGER; OUTCOME ASSESSMENT; PATIENT CARE; PRIMARY MEDICAL CARE; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; SOUTH AFRICAN; TREATMENT FAILURE; ANTIRETROVIRAL THERAPY (HIGHLY ACTIVE); COMPARATIVE STUDY; DECENTRALIZATION; DESCENTRALIZACIÓN; DÉCENTRALISATION; DÉLÉGATION DES TÂCHES; HEALTH CARE DELIVERY; HEALTH CARE PLANNING; HUMAN IMMUNODEFICIENCY VIRUS; LOSS TO FOLLOW-UP; MANPOWER; NURSE; ORGANIZATION AND MANAGEMENT; OUTPATIENT DEPARTMENT; PATIENT REFERRAL; PERDU AU SUIVI; PÉRDIDA DURANTE EL SEGUIMIENTO; PHYSICIAN; POLITICS; PRIMARY HEALTH CARE; PROGRAMME OUTCOMES; RESULTADOS DE PROGRAMA; RETENCIÓN; RETENTION; RÉSULTATS DU PROGRAMME; RÉTENTION; ROTACIÓN DE TAREAS; SOUTH AFRICA; TASK SHIFTING; TERAPIA ANTIRRETROVIRAL (ALTAMENTE ACTIVA); THÉRAPIE ANTIRÉTROVIRALE (TRÈS ACTIVE); VIROLOGY;

CAPE TOWN; SOUTH AFRICA; WESTERN CAPE;

ANTIRETROVIRAL THERAPY (HIGHLY ACTIVE); DECENTRALIZATION; DESCENTRALIZACIÓN; DÉCENTRALISATION; DÉLÉGATION DES TÂCHES; LOSS TO FOLLOW-UP; PERDU AU SUIVI; PÉRDIDA DURANTE EL SEGUIMIENTO; PROGRAMME OUTCOMES; RESULTADOS DE PROGRAMA; RETENCIÓN; RETENTION; RÉSULTATS DU PROGRAMME; RÉTENTION; ROTACIÓN DE TAREAS; TASK SHIFTING; TERAPIA ANTIRRETROVIRAL (ALTAMENTE ACTIVA); THÉRAPIE ANTIRÉTROVIRALE (TRÈS ACTIVE);

ADULT; AMBULATORY CARE FACILITIES; ANTI-HIV AGENTS; DELIVERY OF HEALTH CARE; FEMALE; HEALTH RESOURCES; HEALTH SERVICES; HIV; HIV INFECTIONS; HUMANS; LOST TO FOLLOW-UP; MALE; NURSES; PHYSICIANS; POLITICS; PRIMARY HEALTH CARE; PROPORTIONAL HAZARDS MODELS; PUBLIC SECTOR; REFERRAL AND CONSULTATION; SOUTH AFRICA; TREATMENT FAILURE;

EID: 84907285434     PISSN: 13602276     EISSN: 13653156     Source Type: Journal    
DOI: 10.1111/tmi.12346     Document Type: Article

References (35)

1. Alamo ST, Colebunders R, Ouma J et al. (2012) Return to normal life after AIDS as a reason for lost to follow-up in a community-based antiretroviral treatment program. Journal of Acquired Immune Deficiency Syndromes 60, e36-e45.
2. Bekker LG, Orrell C, Reader L et al. (2003) Antiretroviral therapy in a community clinic-early lessons from a pilot project. South African Medical Journal 93, 458-462.
3. Bekker L-G, Myer L, Orrell C, Lawn S & Wood R (2006) Rapid scale-up of a community-based HIV treatment service: programme performance over 3 consecutive years in Guguletu, South Africa. South African Medical Journal 96, 315-320.
4. Bemelmans M, Van Den Akker T, Ford N et al. (2010) Providing universal access to antiretroviral therapy in Thyolo, Malawi through task shifting and decentralization of HIV/AIDS care. Tropical Medicine & International Health 15, 413-420.
5. Boulle A, Van Cutsem G, Hilderbrand K et al. (2010) Seven-year experience of a primary care antiretroviral treatment programme in Khayelitsha, South Africa. AIDS 24, 563-572.
6. Brennan AT, Long L, Maskew M et al. (2011) Outcomes of stable HIV-positive patients down-referred from a doctor-managed antiretroviral therapy clinic to a nurse-managed primary health clinic for monitoring and treatment. AIDS 25, 2027-2036.
7. Brinkhof MW, Dabis F, Myer L et al. (2008) Early loss of HIV-infected patients on potent antiretroviral therapy programmes in lower-income countries. Bulletin of the World Health Organization 86, 559-567.
8. Brinkhof MWG, Pujades-Rodriguez M & Egger M (2009) Mortality of patients lost to follow-up in antiretroviral treatment programmes in resource-limited settings: systematic review and meta-analysis. PLoS One 4, e5790.
9. Cornell M, Grimsrud A, Fairall L et al. (2010) Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007. AIDS 24, 2263-2270.
10. Decroo T, Panunzi I, das Dores C et al. (2009) Lessons learned during down referral of antiretroviral treatment in Tete, Mozambique. Journal of the International AIDS Society 12, 6.
11. Decroo T, Telfer B, Biot M et al. (2011) Distribution of antiretroviral treatment through self-forming groups of patients in Tete Province, Mozambique. Journal of Acquired Immune Deficiency Syndromes 56, e39-e44.
12. Fatti G, Grimwood A & Bock P (2010) Better antiretroviral therapy outcomes at primary healthcare facilities: an evaluation of three tiers of ART services in four South African provinces. PLoS One 5, e12888.
13. Ford N & Mills EJ (2011) Simplified ART delivery models are needed for the next phase of scale up. PLoS Medicine 8, e1001060.
14. Fox MP, Brennan A, Maskew M, MacPhail P & Sanne I (2010) Using vital registration data to update mortality among patients lost to follow-up from ART programmes: evidence from the Themba Lethu Clinic, South Africa. Tropical Medicine & International Health 15, 405-413.
15. Geng EH, Nash D, Kambugu A et al. (2010) Retention in care among HIV-infected patients in resource-limited settings: emerging insights and new directions. Current HIV/AIDS Reports 7, 234-244.
16. Grimsrud AT, Cornell M, Egger M, Boulle A & Myer L (2013) Impact of definitions of loss to follow-up (LTFU) in antiretroviral therapy program evaluation: variation in the definition can have an appreciable impact on estimated proportions of LTFU. Journal of Clinical Epidemiology 66, 1006-1013.
17. Harries AD, Zachariah R, Lawn SD & Rosen S (2010) Strategies to improve patient retention on antiretroviral therapy in sub-Saharan Africa. Tropical Medicine & International Health 15 (Suppl. 1), 70-75.
18. Lawn SD, Kaplan R, Wood R & Bekker LG (2007) Promoting retention in care: an effective model in an antiretroviral treatment service in South Africa. Clinical Infectious Diseases 45, 803.
19. Lehmann U, Van Damme W, Barten F & Sanders D (2009) Task shifting: the answer to the human resources crisis in Africa? Human Resources for Health 7, 49.
20. Long L, Brennan A, Fox MP et al. (2011) Treatment outcomes and cost-effectiveness of shifting management of stable ART patients to nurses in South Africa: an observational cohort. PLoS Medicine 8, e1001055.
21. Luque-Fernandez MA, Van Cutsem G, Goemaere E et al. (2013) Effectiveness of patient adherence groups as a model of care for stable patients on antiretroviral therapy in Khayelitsha, Cape Town, South Africa. PLoS One 8, e56088.
22. McGuire M, Pinoges L, Kanapathipillai R et al. (2012) Treatment initiation, program attrition and patient treatment outcomes associated with scale-up and decentralization of HIV care in rural Malawi. PLoS One 7, e38044.
23. McMahon JH, Elliott JH, Hong SY, Bertagnolio S & Jordan MR (2013) Effects of physical tracing on estimates of loss to follow-up, mortality and retention in low and middle income country antiretroviral therapy programs: a systematic review. PLoS One 8, e56047.
24. Mutevedzi PC, Lessells RJ, Heller T, Barnighausen T, Cooke GS, Newell ML (2010) Scale-up of a decentralized HIV treatment programme in rural KwaZulu-Natal, South Africa: does rapid expansion affect patient outcomes? Bulletin of the World Health Organization 88, 593-600.
25. Ochieng-Ooko V, Ochieng D, Sidle JE et al. (2010) Influence of gender on loss to follow-up in a large HIV treatment programme in western Kenya. Bulletin of the World Health Organization 88, 681-688.
26. Sanne I, Orrell C, Fox MP et al. (2010) Nurse versus doctor management of HIV-infected patients receiving antiretroviral therapy (CIPRA-SA): a randomised non-inferiority trial. Lancet 376, 33-40.
27. Schneider H & Lehmann U (2010) Lay health workers and HIV programmes: implications for health systems. AIDS Care 22 (Suppl. 1), 60-67.
28. Selke HM, Kimaiyo S, Sidle JE et al. (2010) Task-shifting of antiretroviral delivery from health care workers to persons living with HIV/AIDS: clinical outcomes of a community-based program in Kenya. Journal of Acquired Immune Deficiency Syndromes 55, 483-490.
29. Sherr K, Pfeiffer J, Mussa A et al. (2009) The role of nonphysician clinicians in the rapid expansion of HIV care in Mozambique. Journal of Acquired Immune Deficiency Syndromes 52 (Suppl. 1), S20-S23.
30. UNAIDS (2013) Global Report: UNAIDS Report on the Global AIDS Epidemic in 2013. UNAIDS, Geneva.
31. Van Cutsem G, Ford N, Hildebrand K et al. (2011) Correcting for mortality among patients lost to follow up on antiretroviral therapy in South Africa: a cohort analysis. PLoS One 6, e14684.
32. World Health Organization (2013a) Global Update on HIV Treatment 2013: Results, Impact and Opportunities. World Health Organization, Geneva.
33. World Health Organization (2013b) Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach. World Health Organization, Geneva.
34. World Health Organization (2014) March 2014 Supplement to the 2013 Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection. Recommendations for A Public Health Approach. World Health Organization, Geneva.
35. Zachariah R, Ford N, Philips M et al. (2009) Task shifting in HIV/AIDS: opportunities, challenges and proposed actions for sub-Saharan Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene 103, 549-558.