Determination of tacrolimus crystalline fraction in the commercial immediate release amorphous solid dispersion products by a standardized X-ray powder diffraction method with chemometrics

International Journal of Pharmaceutics

Volumn 475, Issue 1, 2014, Pages 462-470

  Rahman, Ziyaur ^a   Siddiqui, Akhtar ^a   Bykadi, Srikant ^a   Khan, Mansoor A ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Amorphous solid dispersion; Partial least square regression; Principle component regression; Tacrolimus; X ray powder diffraction

Indexed keywords

EXCIPIENT; TACROLIMUS;

ARTICLE; CALIBRATION; CHEMOMETRIC ANALYSIS; CHEMOMETRICS; CONTROLLED STUDY; DISPERSION; DRUG DETERMINATION; MEASUREMENT ACCURACY; PARTICLE SIZE; POLYMERASE CHAIN REACTION; STANDARD; SUSTAINED DRUG RELEASE; X RAY POWDER DIFFRACTION; CHEMISTRY; CRYSTALLIZATION; DRUG RELEASE; MEDICINAL CHEMISTRY; PRINCIPAL COMPONENT ANALYSIS; PROCEDURES; SOLUBILITY; X RAY DIFFRACTION;

CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG LIBERATION; PRINCIPAL COMPONENT ANALYSIS; SOLUBILITY; TACROLIMUS; X-RAY DIFFRACTION;

EID: 84907279960     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.08.050     Document Type: Article

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