-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin, D. M., Bray, F., Ferlay, J. and Pisani, P. (2005) Global cancer statistics, 2002. CA Cancer J. Clin. 55, 74-108
-
(2005)
CA Cancer J. Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
2
-
-
77950616983
-
A meta-analysis of survival rates of untreated patients in randomized clinical trials of hepatocellular carcinoma
-
Cabibbo, G., Enea, M., Attanasio, M., Bruix, J., Craxi, A. and Camma, C. (2010) A meta-analysis of survival rates of untreated patients in randomized clinical trials of hepatocellular carcinoma. Hepatology 51, 1274-1283
-
(2010)
Hepatology
, vol.51
, pp. 1274-1283
-
-
Cabibbo, G.1
Enea, M.2
Attanasio, M.3
Bruix, J.4
Craxi, A.5
Camma, C.6
-
3
-
-
0141491273
-
Hepatocellular carcinoma
-
Llovet, J. M., Burroughs, A. and Bruix, J. (2003) Hepatocellular carcinoma. Lancet 362, 1907-1917
-
(2003)
Lancet
, vol.362
, pp. 1907-1917
-
-
Llovet, J.M.1
Burroughs, A.2
Bruix, J.3
-
4
-
-
34250020201
-
Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
-
El Serag, H. B. and Rudolph, K. L. (2007) Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132, 2557-2576
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El Serag, H.B.1
Rudolph, K.L.2
-
5
-
-
0033545541
-
Rising incidence of hepatocellular carcinoma in the United States
-
El Serag, H. B. and Mason, A. C. (1999) Rising incidence of hepatocellular carcinoma in the United States. N. Engl. J. Med. 340, 745-750
-
(1999)
N. Engl. J. Med
, vol.340
, pp. 745-750
-
-
El Serag, H.B.1
Mason, A.C.2
-
6
-
-
31344442795
-
Increasing hepatitis C virus-associated hepatocellular carcinoma mortality and aging: long term trends in Japan
-
Taura, N., Yatsuhashi, H., Hamasaki, K., Nakao, K., Daikoku, M., Ueki, T., Yano, K., Matsumoto, T., Ishibashi, H. and Eguchi, K. (2006) Increasing hepatitis C virus-associated hepatocellular carcinoma mortality and aging: long term trends in Japan. Hepatol. Res. 34, 130-134
-
(2006)
Hepatol. Res
, vol.34
, pp. 130-134
-
-
Taura, N.1
Yatsuhashi, H.2
Hamasaki, K.3
Nakao, K.4
Daikoku, M.5
Ueki, T.6
Yano, K.7
Matsumoto, T.8
Ishibashi, H.9
Eguchi, K.10
-
7
-
-
33750606061
-
Long-term follow-up of patients with NAFLD and elevated liver enzymes
-
Ekstedt, M., Franzen, L. E., Mathiesen, U. L., Thorelius, L., Holmqvist, M., Bodemar, G. and Kechagias, S. (2006) Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 44, 865-873
-
(2006)
Hepatology
, vol.44
, pp. 865-873
-
-
Ekstedt, M.1
Franzen, L.E.2
Mathiesen, U.L.3
Thorelius, L.4
Holmqvist, M.5
Bodemar, G.6
Kechagias, S.7
-
8
-
-
7044272630
-
Hepatocellular carcinoma in cirrhosis: incidence and risk factors
-
Fattovich, G., Stroffolini, T., Zagni, I. and Donato, F. (2004) Hepatocellular carcinoma in cirrhosis: incidence and risk factors. Gastroenterology 127, S35-S50
-
(2004)
Gastroenterology
, vol.127
, pp. S35-S50
-
-
Fattovich, G.1
Stroffolini, T.2
Zagni, I.3
Donato, F.4
-
9
-
-
0032879468
-
Prognosis of hepatocellular carcinoma: the BCLC staging classification
-
Llovet, J. M., Bru, C. and Bruix, J. (1999) Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin. Liver Dis. 19, 329-338
-
(1999)
Semin. Liver Dis
, vol.19
, pp. 329-338
-
-
Llovet, J.M.1
Bru, C.2
Bruix, J.3
-
10
-
-
38649114052
-
Diagnosis of hepatic nodules 20 mm or smaller in cirrhosis: prospective validation of the noninvasive diagnostic criteria for hepatocellular carcinoma
-
Forner, A., Vilana, R., Ayuso, C., Bianchi, L., Sole, M., Ayuso, J. R., Boix, L., Sala, M., Varela, M., Llovet, J. M. et al. (2008) Diagnosis of hepatic nodules 20 mm or smaller in cirrhosis: prospective validation of the noninvasive diagnostic criteria for hepatocellular carcinoma. Hepatology 47, 97-104
-
(2008)
Hepatology
, vol.47
, pp. 97-104
-
-
Forner, A.1
Vilana, R.2
Ayuso, C.3
Bianchi, L.4
Sole, M.5
Ayuso, J.R.6
Boix, L.7
Sala, M.8
Varela, M.9
Llovet, J.M.10
-
11
-
-
79952231921
-
Management of hepatocellular carcinoma: an update
-
Bruix, J. and Sherman, M. (2011) Management of hepatocellular carcinoma: an update. Hepatology 53, 1020-1022
-
(2011)
Hepatology
, vol.53
, pp. 1020-1022
-
-
Bruix, J.1
Sherman, M.2
-
12
-
-
33749238553
-
Discovery and development of sorafenib: a multikinase inhibitor for treating cancer
-
Wilhelm, S., Carter, C., Lynch, M., Lowinger, T., Dumas, J., Smith, R. A., Schwartz, B., Simantov, R. and Kelley, S. (2006) Discovery and development of sorafenib: a multikinase inhibitor for treating cancer. Nat. Rev. Drug Discov. 5, 835-844
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 835-844
-
-
Wilhelm, S.1
Carter, C.2
Lynch, M.3
Lowinger, T.4
Dumas, J.5
Smith, R.A.6
Schwartz, B.7
Simantov, R.8
Kelley, S.9
-
13
-
-
79961083736
-
Anti-angiogenesis in hepatocellular carcinoma treatment: current evidence and future perspectives
-
Welker, M. W. and Trojan, J. (2011) Anti-angiogenesis in hepatocellular carcinoma treatment: current evidence and future perspectives. World J. Gastroenterol. 17, 3075-3081
-
(2011)
World J. Gastroenterol
, vol.17
, pp. 3075-3081
-
-
Welker, M.W.1
Trojan, J.2
-
14
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet, J. M., Ricci, S., Mazzaferro, V., Hilgard, P., Gane, E., Blanc, J. F., de Oliveira, A. C., Santoro, A., Raoul, J. L., Forner, A. et al. (2008) Sorafenib in advanced hepatocellular carcinoma. N. Engl. J. Med. 359, 378-390
-
(2008)
N. Engl. J. Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.F.6
de Oliveira, A.C.7
Santoro, A.8
Raoul, J.L.9
Forner, A.10
-
15
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
-
Cheng, A. L., Kang, Y. K., Chen, Z., Tsao, C. J., Qin, S., Kim, J. S., Luo, R., Feng, J., Ye, S., Yang, T. S. et al. (2009) Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol. 10, 25-34
-
(2009)
Lancet Oncol
, vol.10
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
Tsao, C.J.4
Qin, S.5
Kim, J.S.6
Luo, R.7
Feng, J.8
Ye, S.9
Yang, T.S.10
-
16
-
-
79957804864
-
Optimized management of advanced hepatocellular carcinoma: four long-lasting responses to sorafenib
-
Abbadessa, G., Rimassa, L., Pressiani, T., Carrillo-Infante, C., Cucchi, E. and Santoro, A. (2011) Optimized management of advanced hepatocellular carcinoma: four long-lasting responses to sorafenib. World J. Gastroenterol. 17, 2450-2453
-
(2011)
World J. Gastroenterol
, vol.17
, pp. 2450-2453
-
-
Abbadessa, G.1
Rimassa, L.2
Pressiani, T.3
Carrillo-Infante, C.4
Cucchi, E.5
Santoro, A.6
-
17
-
-
84872689584
-
Rapid long-lasting biochemical and radiological response to sorafenib in a case of advanced hepatocellular carcinoma
-
Gerardi, A. M., Stoppino, L. P., Liso, A., Macarini, L. and Landriscina, M. (2013) Rapid long-lasting biochemical and radiological response to sorafenib in a case of advanced hepatocellular carcinoma. Oncol. Lett. 5, 975-977
-
(2013)
Oncol. Lett
, vol.5
, pp. 975-977
-
-
Gerardi, A.M.1
Stoppino, L.P.2
Liso, A.3
Macarini, L.4
Landriscina, M.5
-
18
-
-
67651095716
-
Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma in consideration of concomitant stage of liver cirrhosis
-
Worns, M. A., Weinmann, A., Pfingst, K., Schulte-Sasse, C., Messow, C. M., Schulze-Bergkamen, H., Teufel, A., Schuchmann, M., Kanzler, S., Duber, C. et al. (2009) Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma in consideration of concomitant stage of liver cirrhosis. J. Clin. Gastroenterol. 43, 489-495
-
(2009)
J. Clin. Gastroenterol
, vol.43
, pp. 489-495
-
-
Worns, M.A.1
Weinmann, A.2
Pfingst, K.3
Schulte-Sasse, C.4
Messow, C.M.5
Schulze-Bergkamen, H.6
Teufel, A.7
Schuchmann, M.8
Kanzler, S.9
Duber, C.10
-
19
-
-
84907191940
-
Use of sorafenib in advanced hepatocellular carcinoma-a case study of a German Liver Center
-
Welker, M. W., Lubomierski, N., Gog, C., Herrmann, E., Engels, K., Vogl, T., Bechstein, W., Zeuzem, S. and Trojan, J. (2010) Use of sorafenib in advanced hepatocellular carcinoma-a case study of a German Liver Center. Onkologie 33, 86-86
-
(2010)
Onkologie
, vol.33
, pp. 86-86
-
-
Welker, M.W.1
Lubomierski, N.2
Gog, C.3
Herrmann, E.4
Engels, K.5
Vogl, T.6
Bechstein, W.7
Zeuzem, S.8
Trojan, J.9
-
20
-
-
84862640821
-
Usefulness of alpha-fetoprotein response in patients treated with sorafenib for advanced hepatocellular carcinoma
-
Personeni, N., Bozzarelli, S., Pressiani, T., Rimassa, L., Tronconi, M. C., Sclafani, F., Carnaghi, C., Pedicini, V., Giordano, L. and Santoro, A. (2012) Usefulness of alpha-fetoprotein response in patients treated with sorafenib for advanced hepatocellular carcinoma. J. Hepatol. 57, 101-107
-
(2012)
J. Hepatol
, vol.57
, pp. 101-107
-
-
Personeni, N.1
Bozzarelli, S.2
Pressiani, T.3
Rimassa, L.4
Tronconi, M.C.5
Sclafani, F.6
Carnaghi, C.7
Pedicini, V.8
Giordano, L.9
Santoro, A.10
-
21
-
-
79952754331
-
MicroRNA dysregulation in cancer: opportunities for the development of microRNA-based drugs
-
Nana-Sinkam, S. P. and Croce, C. M. (2010) MicroRNA dysregulation in cancer: opportunities for the development of microRNA-based drugs. IDrugs 13, 843-846
-
(2010)
IDrugs
, vol.13
, pp. 843-846
-
-
Nana-Sinkam, S.P.1
Croce, C.M.2
-
22
-
-
67651002343
-
Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell
-
Sotiropoulou, G., Pampalakis, G., Lianidou, E. and Mourelatos, Z. (2009) Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. RNA 15, 1443-1461
-
(2009)
RNA
, vol.15
, pp. 1443-1461
-
-
Sotiropoulou, G.1
Pampalakis, G.2
Lianidou, E.3
Mourelatos, Z.4
-
23
-
-
79955372708
-
MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a
-
Toffanin, S., Hoshida, Y., Lachenmayer, A., Villanueva, A., Cabellos, L., Minguez, B., Savic, R., Ward, S. C., Thung, S., Chiang, D. Y. et al. (2011) MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a. Gastroenterology 140, 1618-1628
-
(2011)
Gastroenterology
, vol.140
, pp. 1618-1628
-
-
Toffanin, S.1
Hoshida, Y.2
Lachenmayer, A.3
Villanueva, A.4
Cabellos, L.5
Minguez, B.6
Savic, R.7
Ward, S.C.8
Thung, S.9
Chiang, D.Y.10
-
24
-
-
0041842492
-
Image-guided tumor ablation: proposal for standardization of terms and reporting criteria
-
Goldberg, S. N., Charboneau, J. W., Dodd, III, G. D., Dupuy, D. E., Gervais, D. A., Gillams, A. R., Kane, R. A., Lee, Jr, F. T., Livraghi, T., McGahan, J. P. et al. (2003) Image-guided tumor ablation: proposal for standardization of terms and reporting criteria. Radiology 228, 335-345
-
(2003)
Radiology
, vol.228
, pp. 335-345
-
-
Goldberg, S.N.1
Charboneau, J.W.2
Dodd III, G.D.3
Dupuy, D.E.4
Gervais, D.A.5
Gillams, A.R.6
Kane, R.A.7
Lee Jr, F.T.8
Livraghi, T.9
McGahan, J.P.10
-
25
-
-
0032919364
-
KEGG: Kyoto encyclopedia of genes and genomes
-
Ogata, H., Goto, S., Sato, K., Fujibuchi, W., Bono, H. and Kanehisa, M. (1999) KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 27, 29-34
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 29-34
-
-
Ogata, H.1
Goto, S.2
Sato, K.3
Fujibuchi, W.4
Bono, H.5
Kanehisa, M.6
-
26
-
-
0001677717
-
Controlling the false discovery rate: a practical and powerful approach to multiple testing
-
Benjamini, Y. and Hochberg, Y. (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J.R. Statist. Soc. B 57, 289-300
-
(1995)
J.R. Statist. Soc. B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
27
-
-
84864464973
-
DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways
-
Vlachos, I. S., Kostoulas, N., Vergoulis, T., Georgakilas, G., Reczko, M., Maragkakis, M., Paraskevopoulou, M. D., Prionidis, K., Dalamagas, T. and Hatzigeorgiou, A. G. (2012) DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways. Nucleic Acids Res. 40, W498-W504
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. W498-W504
-
-
Vlachos, I.S.1
Kostoulas, N.2
Vergoulis, T.3
Georgakilas, G.4
Reczko, M.5
Maragkakis, M.6
Paraskevopoulou, M.D.7
Prionidis, K.8
Dalamagas, T.9
Hatzigeorgiou, A.G.10
-
28
-
-
79955401037
-
Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma
-
Villanueva, A., Hoshida, Y., Battiston, C., Tovar, V., Sia, D., Alsinet, C., Cornella, H., Liberzon, A., Kobayashi, M., Kumada, H. et al. (2011) Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma. Gastroenterology 140, 1501-1512
-
(2011)
Gastroenterology
, vol.140
, pp. 1501-1512
-
-
Villanueva, A.1
Hoshida, Y.2
Battiston, C.3
Tovar, V.4
Sia, D.5
Alsinet, C.6
Cornella, H.7
Liberzon, A.8
Kobayashi, M.9
Kumada, H.10
-
29
-
-
34548781396
-
Genetic diversity of hepatocellular carcinomas and its potential impact on targeted therapies
-
Zucnan-Rossi, J. and Laurent-Puig, P. (2007) Genetic diversity of hepatocellular carcinomas and its potential impact on targeted therapies. Pharmacogenomics 8, 997-1003
-
(2007)
Pharmacogenomics
, vol.8
, pp. 997-1003
-
-
Zucnan-Rossi, J.1
Laurent-Puig, P.2
-
30
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros, V. (2004) The functions of animal microRNAs. Nature 431, 350-355
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
31
-
-
78650436438
-
The microRNA miR-139 suppresses metastasis and progression of hepatocellular carcinoma by down-regulating Rho-kinase 2
-
Wong, C. C., Wong, C. M., Tung, E. K., Au, S. L., Lee, J. M., Poon, R. T., Man, K. and Ng, I. O. (2011) The microRNA miR-139 suppresses metastasis and progression of hepatocellular carcinoma by down-regulating Rho-kinase 2. Gastroenterology 140, 322-331
-
(2011)
Gastroenterology
, vol.140
, pp. 322-331
-
-
Wong, C.C.1
Wong, C.M.2
Tung, E.K.3
Au, S.L.4
Lee, J.M.5
Poon, R.T.6
Man, K.7
Ng, I.O.8
-
32
-
-
77950602604
-
Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma
-
Xiong, Y., Fang, J. H., Yun, J. P., Yang, J., Zhang, Y., Jia, W. H. and Zhuang, S. M. (2010) Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma. Hepatology 51, 836-845
-
(2010)
Hepatology
, vol.51
, pp. 836-845
-
-
Xiong, Y.1
Fang, J.H.2
Yun, J.P.3
Yang, J.4
Zhang, Y.5
Jia, W.H.6
Zhuang, S.M.7
-
33
-
-
84883476367
-
Clinical significance and prognostic value of microRNA expression signatures in hepatocellular carcinoma
-
Wei, R., Huang, G. L., Zhang, M. Y., Li, B. K., Zhang, H. Z., Shi, M., Chen, X. Q., Huang, L., Zhou, Q. M., Jia, W. H. et al. (2013) Clinical significance and prognostic value of microRNA expression signatures in hepatocellular carcinoma. Clin. Cancer Res. 19, 4780-4791
-
(2013)
Clin. Cancer Res
, vol.19
, pp. 4780-4791
-
-
Wei, R.1
Huang, G.L.2
Zhang, M.Y.3
Li, B.K.4
Zhang, H.Z.5
Shi, M.6
Chen, X.Q.7
Huang, L.8
Zhou, Q.M.9
Jia, W.H.10
-
34
-
-
84881028557
-
MicroRNA-216a/217- induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer
-
Xia, H., Ooi, L. L. and Hui, K. M. (2013) MicroRNA-216a/217- induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer. Hepatology 58, 629-641
-
(2013)
Hepatology
, vol.58
, pp. 629-641
-
-
Xia, H.1
Ooi, L.L.2
Hui, K.M.3
-
35
-
-
84887014620
-
MiR-146a enhances angiogenic activity of endothelial cells in hepatocellular carcinoma by promoting PDGFRA expression
-
Zhu, K., Pan, Q., Zhang, X., Kong, L. Q., Fan, J., Dai, Z., Wang, L., Yang, X. R., Hu, J., Wan, J. L. et al. (2013) MiR-146a enhances angiogenic activity of endothelial cells in hepatocellular carcinoma by promoting PDGFRA expression. Carcinogenesis 34, 2071-2079
-
(2013)
Carcinogenesis
, vol.34
, pp. 2071-2079
-
-
Zhu, K.1
Pan, Q.2
Zhang, X.3
Kong, L.Q.4
Fan, J.5
Dai, Z.6
Wang, L.7
Yang, X.R.8
Hu, J.9
Wan, J.L.10
-
36
-
-
79751484450
-
Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma
-
Hou, J., Lin, L., Zhou, W., Wang, Z., Ding, G., Dong, Q., Qin, L., Wu, X., Zheng, Y., Yang, Y. et al. (2011) Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell 19, 232-243
-
(2011)
Cancer Cell
, vol.19
, pp. 232-243
-
-
Hou, J.1
Lin, L.2
Zhou, W.3
Wang, Z.4
Ding, G.5
Dong, Q.6
Qin, L.7
Wu, X.8
Zheng, Y.9
Yang, Y.10
-
37
-
-
38949184246
-
Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival
-
Jiang, J., Gusev, Y., Aderca, I., Mettler, T. A., Nagorney, D. M., Brackett, D. J., Roberts, L. R. and Schmittgen, T. D. (2008) Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival. Clin. Cancer Res. 14, 419-427
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 419-427
-
-
Jiang, J.1
Gusev, Y.2
Aderca, I.3
Mettler, T.A.4
Nagorney, D.M.5
Brackett, D.J.6
Roberts, L.R.7
Schmittgen, T.D.8
-
38
-
-
51349165812
-
Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype
-
Connolly, E., Melegari, M., Landgraf, P., Tchaikovskaya, T., Tennant, B. C., Slagle, B. L., Rogler, L. E., Zavolan, M., Tuschl, T. and Rogler, C. E. (2008) Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype. Am. J. Pathol. 173, 856-864
-
(2008)
Am. J. Pathol
, vol.173
, pp. 856-864
-
-
Connolly, E.1
Melegari, M.2
Landgraf, P.3
Tchaikovskaya, T.4
Tennant, B.C.5
Slagle, B.L.6
Rogler, L.E.7
Zavolan, M.8
Tuschl, T.9
Rogler, C.E.10
-
39
-
-
34447117003
-
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma
-
Gramantieri, L., Ferracin, M., Fornari, F., Veronese, A., Sabbioni, S., Liu, C. G., Calin, G. A., Giovannini, C., Ferrazzi, E., Grazi, G. L. et al. (2007) Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Res. 67, 6092-6099
-
(2007)
Cancer Res
, vol.67
, pp. 6092-6099
-
-
Gramantieri, L.1
Ferracin, M.2
Fornari, F.3
Veronese, A.4
Sabbioni, S.5
Liu, C.G.6
Calin, G.A.7
Giovannini, C.8
Ferrazzi, E.9
Grazi, G.L.10
-
40
-
-
68349160639
-
Bead-based microarray analysis of microRNA expression in hepatocellular carcinoma: miR-338 is downregulated
-
Huang, X. H., Wang, Q., Chen, J. S., Fu, X. H., Chen, X. L., Chen, L. Z., Li, W., Bi, J., Zhang, L. J., Fu, Q. et al. (2009) Bead-based microarray analysis of microRNA expression in hepatocellular carcinoma: miR-338 is downregulated. Hepatol. Res. 39, 786-794
-
(2009)
Hepatol. Res
, vol.39
, pp. 786-794
-
-
Huang, X.H.1
Wang, Q.2
Chen, J.S.3
Fu, X.H.4
Chen, X.L.5
Chen, L.Z.6
Li, W.7
Bi, J.8
Zhang, L.J.9
Fu, Q.10
-
41
-
-
0034856294
-
Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver
-
J. Hepatol
-
Bruix, J., Sherman, M., Llovet, J. M., Beaugrand, M., Lencioni, R., Burroughs, A. K., Christensen, E., Pagliaro, L., Colombo, M. and Rodes, J. (2001) Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. J. Hepatol. 35, 421-430
-
(2001)
, vol.35
, pp. 421-430
-
-
Bruix, J.1
Sherman, M.2
Llovet, J.M.3
Beaugrand, M.4
Lencioni, R.5
Burroughs, A.K.6
Christensen, E.7
Pagliaro, L.8
Colombo, M.9
Rodes, J.10
-
42
-
-
33646157967
-
Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues
-
Murakami, Y., Yasuda, T., Saigo, K., Urashima, T., Toyoda, H., Okanoue, T. and Shimotohno, K. (2006) Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene 25, 2537-2545
-
(2006)
Oncogene
, vol.25
, pp. 2537-2545
-
-
Murakami, Y.1
Yasuda, T.2
Saigo, K.3
Urashima, T.4
Toyoda, H.5
Okanoue, T.6
Shimotohno, K.7
-
43
-
-
42449151984
-
Evaluation and validation of total RNA extraction methods for microRNA expression analyses in formalin-fixed, paraffin-embedded tissues
-
Doleshal, M., Magotra, A. A., Choudhury, B., Cannon, B. D., Labourier, E. and Szafranska, A. E. (2008) Evaluation and validation of total RNA extraction methods for microRNA expression analyses in formalin-fixed, paraffin-embedded tissues. J. Mol. Diagn. 10, 203-211
-
(2008)
J. Mol. Diagn
, vol.10
, pp. 203-211
-
-
Doleshal, M.1
Magotra, A.A.2
Choudhury, B.3
Cannon, B.D.4
Labourier, E.5
Szafranska, A.E.6
-
44
-
-
79958289412
-
MicroRNA isolation from formalin-fixed, paraffin-embedded tissues
-
Liu, A. and Xu, X. (2011) MicroRNA isolation from formalin-fixed, paraffin-embedded tissues. Methods Mol. Biol. 724, 259-267
-
(2011)
Methods Mol. Biol
, vol.724
, pp. 259-267
-
-
Liu, A.1
Xu, X.2
-
45
-
-
84870527046
-
Plasma microRNA profile as a predictor of early virological response to interferon treatment in chronic hepatitis B patients
-
Zhang, X., Chen, C., Wu, M., Chen, L., Zhang, J., Zhang, X., Zhang, Z., Wu, J., Wang, J., Chen, X. et al. (2012) Plasma microRNA profile as a predictor of early virological response to interferon treatment in chronic hepatitis B patients. Antivir. Ther. 17, 1243-1253
-
(2012)
Antivir. Ther
, vol.17
, pp. 1243-1253
-
-
Zhang, X.1
Chen, C.2
Wu, M.3
Chen, L.4
Zhang, J.5
Zhang, X.6
Zhang, Z.7
Wu, J.8
Wang, J.9
Chen, X.10
-
46
-
-
34447117003
-
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma
-
Gramantieri, L., Ferracin, M., Fornari, F., Veronese, A., Sabbioni, S., Liu, C. G., Calin, G. A., Giovannini, C., Ferrazzi, E., Grazi, G. L. et al. (2007) Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Res. 67, 6092-6099
-
(2007)
Cancer Res
, vol.67
, pp. 6092-6099
-
-
Gramantieri, L.1
Ferracin, M.2
Fornari, F.3
Veronese, A.4
Sabbioni, S.5
Liu, C.G.6
Calin, G.A.7
Giovannini, C.8
Ferrazzi, E.9
Grazi, G.L.10
-
47
-
-
78649561463
-
Hsa-let-7g inhibits proliferation of hepatocellular carcinoma cells by downregulation of c-Myc and upregulation of p16(INK4A)
-
Lan, F. F., Wang, H., Chen, Y. C., Chan, C. Y., Ng, S. S., Li, K., Xie, D., He, M. L., Lin, M. C. and Kung, H. F. (2011) Hsa-let-7g inhibits proliferation of hepatocellular carcinoma cells by downregulation of c-Myc and upregulation of p16(INK4A). Int. J. Cancer 128, 319-331
-
(2011)
Int. J. Cancer
, vol.128
, pp. 319-331
-
-
Lan, F.F.1
Wang, H.2
Chen, Y.C.3
Chan, C.Y.4
Ng, S.S.5
Li, K.6
Xie, D.7
He, M.L.8
Lin, M.C.9
Kung, H.F.10
-
48
-
-
84874324650
-
miR-126&126.*restored expressions play a tumor suppressor role by directly regulating ADAM9 and MMP7 in melanoma
-
Felli, N., Felicetti, F., Lustri, A. M., Errico, M. C., Bottero, L., Cannistraci, A., De Feo, A., Petrini, M., Pedini, F., Biffoni, M. et al. (2013) miR-126&126.*restored expressions play a tumor suppressor role by directly regulating ADAM9 and MMP7 in melanoma. PloS One 8, e56824
-
(2013)
PloS One
, vol.8
, pp. e56824
-
-
Felli, N.1
Felicetti, F.2
Lustri, A.M.3
Errico, M.C.4
Bottero, L.5
Cannistraci, A.6
De Feo, A.7
Petrini, M.8
Pedini, F.9
Biffoni, M.10
-
49
-
-
66449136951
-
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
-
Kota, J., Chivukula, R. R., O'Donnell, K. A., Wentzel, E. A., Montgomery, C. L., Hwang, H. W., Chang, T. C., Vivekanandan, P., Torbenson, M., Clark, K. R. et al. (2009) Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137, 1005-1017
-
(2009)
Cell
, vol.137
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'Donnell, K.A.3
Wentzel, E.A.4
Montgomery, C.L.5
Hwang, H.W.6
Chang, T.C.7
Vivekanandan, P.8
Torbenson, M.9
Clark, K.R.10
-
50
-
-
81855183267
-
microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer
-
Braconi, C., Kogure, T., Valeri, N., Huang, N., Nuovo, G., Costinean, S., Negrini, M., Miotto, E., Croce, C. M. and Patel, T. (2011) microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. Oncogene 30, 4750-4756
-
(2011)
Oncogene
, vol.30
, pp. 4750-4756
-
-
Braconi, C.1
Kogure, T.2
Valeri, N.3
Huang, N.4
Nuovo, G.5
Costinean, S.6
Negrini, M.7
Miotto, E.8
Croce, C.M.9
Patel, T.10
-
51
-
-
80054694898
-
MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma
-
Li, D., Liu, X., Lin, L., Hou, J., Li, N., Wang, C., Wang, P., Zhang, Q., Zhang, P., Zhou, W. et al. (2011) MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma. J. Biol. Chem. 286, 36677-36685
-
(2011)
J. Biol. Chem
, vol.286
, pp. 36677-36685
-
-
Li, D.1
Liu, X.2
Lin, L.3
Hou, J.4
Li, N.5
Wang, C.6
Wang, P.7
Zhang, Q.8
Zhang, P.9
Zhou, W.10
-
52
-
-
84867742828
-
Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression
-
Petrelli, A., Perra, A., Schernhuber, K., Cargnelutti, M., Salvi, A., Migliore, C., Ghiso, E., Benetti, A., Barlati, S., Ledda-Columbano, G. M. et al. (2012) Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression. Oncogene 31, 4517-4526
-
(2012)
Oncogene
, vol.31
, pp. 4517-4526
-
-
Petrelli, A.1
Perra, A.2
Schernhuber, K.3
Cargnelutti, M.4
Salvi, A.5
Migliore, C.6
Ghiso, E.7
Benetti, A.8
Barlati, S.9
Ledda-Columbano, G.M.10
-
53
-
-
0034767501
-
Transforming growth factor beta and the liver
-
Bissell, D. M., Roulot, D. and George, J. (2001) Transforming growth factor beta and the liver. Hepatology 34, 859-867
-
(2001)
Hepatology
, vol.34
, pp. 859-867
-
-
Bissell, D.M.1
Roulot, D.2
George, J.3
-
54
-
-
33745552897
-
Dysregulation of growth factor signaling in human hepatocellular carcinoma
-
Breuhahn, K., Longerich, T. and Schirmacher, P. (2006) Dysregulation of growth factor signaling in human hepatocellular carcinoma. Oncogene 25, 3787-3800
-
(2006)
Oncogene
, vol.25
, pp. 3787-3800
-
-
Breuhahn, K.1
Longerich, T.2
Schirmacher, P.3
-
55
-
-
84869194238
-
Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells
-
Grabinski, N., Ewald, F., Hofmann, B. T., Staufer, K., Schumacher, U., Nashan, B. and Jucker, M. (2012) Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells. Mol. Cancer 11, 85
-
(2012)
Mol. Cancer
, vol.11
, pp. 85
-
-
Grabinski, N.1
Ewald, F.2
Hofmann, B.T.3
Staufer, K.4
Schumacher, U.5
Nashan, B.6
Jucker, M.7
-
56
-
-
0035906821
-
Expression and clinical significance of erb-B receptor family in hepatocellular carcinoma
-
Ito, Y., Takeda, T., Sakon, M., Tsujimoto, M., Higashiyama, S., Noda, K., Miyoshi, E., Monden, M. and Matsuura, N. (2001) Expression and clinical significance of erb-B receptor family in hepatocellular carcinoma. Br. J. Cancer 84, 1377-1383
-
(2001)
Br. J. Cancer
, vol.84
, pp. 1377-1383
-
-
Ito, Y.1
Takeda, T.2
Sakon, M.3
Tsujimoto, M.4
Higashiyama, S.5
Noda, K.6
Miyoshi, E.7
Monden, M.8
Matsuura, N.9
-
57
-
-
0036632368
-
The phosphatidylinositol 3-kinase AKT pathway in human cancer
-
Vivanco, I. and Sawyers, C. L. (2002) The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat. Rev. Cancer 2, 489-501
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
58
-
-
84894728095
-
MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer
-
Lim, L., Balakrishnan, A., Huskey, N., Jones, K. D., Jodari, M., Ng, R., Song, G., Riordan, J., Anderton, B., Cheung, S. T. et al. (2014) MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer. Hepatology 59, 202-215
-
(2014)
Hepatology
, vol.59
, pp. 202-215
-
-
Lim, L.1
Balakrishnan, A.2
Huskey, N.3
Jones, K.D.4
Jodari, M.5
Ng, R.6
Song, G.7
Riordan, J.8
Anderton, B.9
Cheung, S.T.10
-
59
-
-
76049107610
-
High expression of microRNA-15b predicts a low risk of tumor recurrence following curative resection of hepatocellular carcinoma
-
Chung, G. E., Yoon, J. H., Myung, S. J., Lee, J. H., Lee, S. H., Lee, S. M., Kim, S. J., Hwang, S. Y., Lee, H. S. and Kim, C. Y. (2010) High expression of microRNA-15b predicts a low risk of tumor recurrence following curative resection of hepatocellular carcinoma. Oncol. Rep. 23, 113-119
-
(2010)
Oncol. Rep
, vol.23
, pp. 113-119
-
-
Chung, G.E.1
Yoon, J.H.2
Myung, S.J.3
Lee, J.H.4
Lee, S.H.5
Lee, S.M.6
Kim, S.J.7
Hwang, S.Y.8
Lee, H.S.9
Kim, C.Y.10
-
60
-
-
84861309121
-
Identification of postoperative prognostic microRNA predictors in hepatocellular carcinoma
-
Huang, Y. H., Lin, K. H., Chen, H. C., Chang, M. L., Hsu, C. W., Lai, M. W., Chen, T. C., Lee, W. C., Tseng, Y. H. and Yeh, C. T. (2012) Identification of postoperative prognostic microRNA predictors in hepatocellular carcinoma. PLoS One 7, e37188
-
(2012)
PLoS One
, vol.7
, pp. e37188
-
-
Huang, Y.H.1
Lin, K.H.2
Chen, H.C.3
Chang, M.L.4
Hsu, C.W.5
Lai, M.W.6
Chen, T.C.7
Lee, W.C.8
Tseng, Y.H.9
Yeh, C.T.10
-
61
-
-
78649697501
-
miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines
-
Henry, J. C., Park, J. K., Jiang, J., Kim, J. H., Nagorney, D. M., Roberts, L. R., Banerjee, S. and Schmittgen, T. D. (2010) miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines. Biochem. Biophys. Res. Commun. 403, 120-125
-
(2010)
Biochem. Biophys. Res. Commun
, vol.403
, pp. 120-125
-
-
Henry, J.C.1
Park, J.K.2
Jiang, J.3
Kim, J.H.4
Nagorney, D.M.5
Roberts, L.R.6
Banerjee, S.7
Schmittgen, T.D.8
-
62
-
-
77953773201
-
MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells
-
Fornari, F., Milazzo, M., Chieco, P., Negrini, M., Calin, G. A., Grazi, G. L., Pollutri, D., Croce, C. M., Bolondi, L. and Gramantieri, L. (2010) MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells. Cancer Res. 70, 5184-5193
-
(2010)
Cancer Res
, vol.70
, pp. 5184-5193
-
-
Fornari, F.1
Milazzo, M.2
Chieco, P.3
Negrini, M.4
Calin, G.A.5
Grazi, G.L.6
Pollutri, D.7
Croce, C.M.8
Bolondi, L.9
Gramantieri, L.10
-
63
-
-
80054959463
-
Underexpressed microRNA-199b-5p targets hypoxia-inducible factor-1alpha in hepatocellular carcinoma and predicts prognosis of hepatocellular carcinoma patients
-
Wang, C., Song, B., Song, W., Liu, J., Sun, A., Wu, D., Yu, H., Lian, J., Chen, L. and Han, J. (2011) Underexpressed microRNA-199b-5p targets hypoxia-inducible factor-1alpha in hepatocellular carcinoma and predicts prognosis of hepatocellular carcinoma patients. J. Gastroenterol. Hepatol. 26, 1630-1637
-
(2011)
J. Gastroenterol. Hepatol
, vol.26
, pp. 1630-1637
-
-
Wang, C.1
Song, B.2
Song, W.3
Liu, J.4
Sun, A.5
Wu, D.6
Yu, H.7
Lian, J.8
Chen, L.9
Han, J.10
|