Propylene cross-bridged macrocyclic bifunctional chelator: A new design for facile bioconjugation and robust 64cu complex stability

Journal of Medicinal Chemistry

Volumn 57, Issue 17, 2014, Pages 7234-7243

  Pandya, Darpan N ^a   Bhatt, Nikunj ^a   An, Gwang Il ^b   Ha, Yeong Su ^a   Soni, Nisarg ^a   Lee, Hochun ^c   Lee, Yong Jin ^b   Kim, Jung Young ^b   Lee, Woonghee ^a   Ahn, Heesu ^a   Yoo, Jeongsoo ^a  

^a Kyungpook National University   (South Korea)

^b Korea Institute of Radiation and Medical Science   (South Korea)

^c Daegu Gyeongbuk Institute of Science and Technology   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

4,11 BIS(CARBOXYMETHYL) 1,4,8,11 TETRAAZABICYCLO[6,6,3]HEXADECANE ISOTHIOCYANATE CYCLIC ARGINYLGLYCYLASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; CARBOXYLIC ACID; CHELATING AGENT; COORDINATION COMPOUND; COPPER 64; PROPYLENE; UNCLASSIFIED DRUG; ALKENE; ARGINYL-GLYCYL-ASPARTIC ACID; COPPER; CYCLAM; HETEROCYCLIC COMPOUND; MACROCYCLIC COMPOUND; OLIGOPEPTIDE;

ALKYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DEPROTECTION REACTION; DRUG CONJUGATION; DRUG DESIGN; DRUG DISTRIBUTION; DRUG STABILITY; DRUG SYNTHESIS; ELECTROCHEMISTRY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; MOUSE; NONHUMAN; PARTITION COEFFICIENT; POSITRON EMISSION TOMOGRAPHY; TISSUE DISTRIBUTION; ANIMAL; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; GLIOBLASTOMA; HUMAN; METABOLISM; NUDE MOUSE; PATHOLOGY; PROCEDURES; RAT; SYNTHESIS; XENOGRAFT;

ALKENES; ANIMALS; CHELATING AGENTS; COORDINATION COMPLEXES; COPPER; COPPER RADIOISOTOPES; DRUG DESIGN; GLIOBLASTOMA; HETEROCYCLIC COMPOUNDS; HUMANS; MACROCYCLIC COMPOUNDS; MICE; MICE, NUDE; MODELS, CHEMICAL; MOLECULAR STRUCTURE; OLIGOPEPTIDES; POSITRON-EMISSION TOMOGRAPHY; RATS; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 84907211109     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm500348z     Document Type: Article

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